Gastrointestinal Polyps Research Articles

Risk factors of gastrointestinal polypectomy concurrent with bleeding in patients with liver cirrhosis

Objective: To investigate and analyze the occurrence and the related risk factors of gastrointestinal polypectomy accompanied by bleeding in patients with liver cirrhosis. Methods: 127 cases of gastrointestinal polyps with cirrhosis who had endoscopy at the Endoscopic Center of Tianjin Third Central Hospital between November 2017 and November 2020 were collected. At the same time, 127 cases of gastrointestinal polyps with non-cirrhosis that were treated by endoscopy were collected for comparison. The occurrence of hemorrhagic complications between the two groups was compared. The effects of age, sex, liver function, peripheral blood leukocytes, hemoglobin, platelets, blood glucose, the international normalized ratio (INR), polyp resection method, polyp location, size, number, endoscopic morphology, pathology, the presence or absence of diabetes, portal vein thrombosis, and esophageal varices on polypectomy bleeding in the cirrhosis group were analyzed. The measurement data between groups were compared using the t-test and rank sum test. The χ (2) test or Fisher's exact probability method, and multivariate logistic regression analysis were used for the comparison of categorical data between groups. Results: The number of polypectomy bleeding cases in the cirrhotic group was 21, with a bleeding rate of 16.5%. The number of bleeding cases in the non-cirrhotic group was 3, with a bleeding rate of 2.4%. The bleeding rate was higher in the cirrhosis group when polypectomy was performed (χ (2) = 14.909, P < 0.001). A univariate analysis of the risk factors for gastrointestinal polypectomy associated with bleeding in patients with liver cirrhosis showed that liver function grading, platelets, INR, hemoglobin, degree of esophageal and gastric varices, and the location, shape, size, and pathology of the polyps had a statistically significant impact on bleeding (P < 0.05). Multivariate logistic regression analysis showed that liver function grade, degree of varicose veins, and polyp location were independent risk factors for bleeding. Patients with Child-Pugh B or C grade liver function were more likely to bleed than those with Child-Pugh A grade (OR = 4.102, 95% CI 1.133 ~ 14.856), gastric polyps were more likely to bleed than colorectal polyps (OR = 27.763, 95% CI 5.567 ~ 138.460), and severe esophagogastric varices were more likely to bleed than no varices or mild to moderate varices (OR = 7.183, 95% CI 1.384 ~ 37.275). Conclusion: Cirrhotic population has higher risk of bleeding during endoscopic gastrointestinal polypectomy than the non-cirrhotic population. Cirrhotic patients with Child-Pugh grades B or C liver function, polyps located in the stomach, severe esophagogastric varices, and other high-risk factors should be listed as a relative contraindication for endoscopic polypectomy.

Peutz–Jeghers Syndrome: A Rare Genetic Cause of Intestinal Obstruction

Peutz–Jeghers syndrome (PJS) is a rare autosomal dominant disorder. The mutation is found in the serine threonine kinase (STK11)/ liver kinase B1 (LKB1) gene on chromosome 19. It impacts 1 out of 50000–200000 individuals. Clinical menifestations include hyperpigmented lesion in oral cavity, lips, fingertips and perianal region. Abdominal pain, Anaemia, Gastrointestinal (GI) bleeding, GI polyp, Intestinal obstruction (mostly due to intussusception) and malignancy are closely interlinked with the disease. We present a 21 years old lady with characteristic hyperpigmented lesions in lips and fingertips with multiple polyps in the GI tract. The patient was presented in general emergency department with abdominal pain and vomiting. Detail workout revealed the diagnosis as PJS. We have plotted the diagnosis according to the WHO criteria due to the lacking of genetic analysis facility. Patients with PJS are at high risk of intestinal and extraintestinal malignancy. Early diagnosis and polypectomy along with surveillance for recurrence may prolong cancer free lifetime.&#x0D; CBMJ 2023 January: Vol. 12 No. 01 P: 115- 120

A Rare PDGFRA Exon 15 Germline Mutation Identified in a Patient With Phenotypic Manifestations Concerning for GIST-Plus Syndrome: A Case Report and Review of Literature.

Molecular alterations in PDGFRA are well-described as drivers of sporadic gastrointestinal stromal tumors (GISTs) and inflammatory fibroid polyps (IFPs). However, a small number of families with germline PDGFRA mutations in exons 12, 14, and 18 have been reported, forming the basis of an autosomal dominant inherited disorder with incomplete penetrance and variable expressivity, now referred to as PDGFRA-mutant syndrome or GIST-plus syndrome. Phenotypic manifestations of this rare syndrome include multiple gastrointestinal GISTS, IFPs, fibrous tumors, and other variable features. Herein, we report the case of a 58-year-old female who presented with a gastric GIST and numerous small intestinal IFPs, found to harbor a previously undescribed germline PDGFRA exon 15 p.G680R mutation. Somatic tumor testing was performed on the GIST, a duodenal IFP, and an ileal IFP utilizing a targeted next-generation sequencing panel, revealing additional and distinct secondary PDGFRA exon 12 somatic mutations in each of the 3 tumors. Our findings raise important considerations regarding mechanisms of tumor development in patients with underlying germline PDGFRA alterations and highlight the potential utility of expanding currently available germline and somatic testing panels to include exons outside the typical hotspot regions.

Upper Gastrointestinal Screening of Polyp Load in Children With Familial Adenomatous Polyposis: Is It Required?

Patients with familial adenomatous polyposis (FAP) have a propensity to form not only large bowel polyps but also upper gastrointestinal (GI) polyps with malignant potential. International guidance suggests that upper GI screening need not begin until patients are at least into their twenties. It is our experience that patients develop upper GI polyps long before this point which have the potential for malignant change. A prospective record of all upper GI endoscopies in children (aged 9 to 17) with FAP was kept across a 12-year period by 1 surgeon in our center. For each scope performed, we recorded the location, histology, and treatment of upper GI polyps. Twent-eight patients aged 9 to 17 underwent a total of 48 esophagogastroduodenoscopies across a 12-year period. Thirty-eight esophagogastroduodenoscopies (79%) identified at least 1 gastric or duodenal polyp in 22 (79%) patients; 10 (36%) patients had gastric adenomas. Eight (29%) patients showed very high numbers of polyps. All 21 patients who had duodenal polyps had adenomas. None had yet developed malignancy, but 1 patient required extensive polyp excision and one is awaiting endoscopic mucosal resection. Our results demonstrate that young people with FAP are at the risk of developing upper GI polyps long before current guidance suggests screening the upper GI tract. We advocate for screening of the upper GI tract to start along with colonoscopy and happen at the same sitting for pediatric and young adult patients with FAP.

Esophageal squamous cell cancer with germline STK11 mutation - A possibility, a nightmare or the Peutz Jeghers Syndrome!

Background: Peutz Jeghers Syndrome (PJS) is characterized by multiple gastrointestinal hamartomatous polyps and muco-cutaneous pigmentation with increased risk of carcinomas of gastrointestinal tract, breast, lung and gynecological tumors. Only 2 % PJS have esophageal cancers, that too adenocarcinoma. So far esophageal Squamous Cell Carcinoma (SCC) has not been reported in association with PJS. We present a unique case in a young female with muco-cutaneous pigmentation who presented with esophageal SCC and was found to have germline Serine/Threonine Kinase 11 (STK11) mutation.

Identification of an Activating PDGFRA Deletion in a Novel Sinonasal Soft Tissue Neoplasm.

Spindle cell tumours in the sinonasal area are diagnostically challenging. We identified a neoplasm that defied histopathological classification using current criteria. The case was subjected to histopathological, immunohistochemical and molecular analysis using a large small variant DNA panel. The tumour comprised cytologically bland epithelioid spindle cells with a rich vasculature, which lack expression of actin and other smooth muscle markers, CD34 and beta-catenin. An activating insertion/deletion in exon 12 of the PDGFRA gene was detected. This alteration has previously been described in gastrointestinal stromal tumours and inflammatory fibroid polyps of the GI tract, but the site, histological, and immunophenotypic features in this tumour are distinct. We describe a novel sinonasal spindle cell tumour characterised by an activating insertion/deletion in exon 12 of PDGFRA. The diagnosis of PDGFRA-activated sinonasal spindle cell tumour should be considered in difficult to classify mesenchymal lesions at this site.

STK11 Causative Variants and Copy Number Variations Identified in Thai Patients With Peutz-Jeghers Syndrome.

Introduction Peutz-Jeghers syndrome (PJS) is a rare autosomal dominant inherited disorder caused by germline mutations in the serine-threonine kinase 11 (STK11) tumor suppressor gene. This syndrome is characterized by hamartomatous gastrointestinal polyps, mucocutaneous melanin pigmentation, and a higher risk of developing various cancers. Methods We summarized the clinical and molecular characteristics of five unrelated Thai patients with PJS. Denaturing high-performance liquid chromatography (DHPLC) screening, coupled with direct DNA sequencing and multiplex ligation-dependent probe amplification (MLPA), were applied for the molecular analysis of STK11. Results A total of four STK11 pathogenic changeswere identified in the five PJS patients, including two frameshift variants (a novel c.199dup, p.Leu67ProfsTer96 and a known c.834_835del, p.Cys278TrpfsTer6) and two types of copy number variations (CNV), exon 1 deletion and exons 2-3 deletion. Among reported STK11 exonic deletions, exon 1 and exons 2-3 deletions were found to be the two most commonly deleted exons. Conclusion All identified STK11 mutations were null mutations that were associated with more severe PJS phenotypes and cancers. This study broadens the phenotypic and mutational spectrum of STK11 in PJS.

Juvenile-like (inflammatory/hyperplastic) mucosal polyps in neurofibromatosis type 1 – a case report

Neurofibromatosis type 1 (NF1) is a disease with an autosomal dominant inheritance caused by a mutation in the gene for neurofibromin. Recently a form of gastrointestinal polyp has been characterised which may be unique to NF1, described as non-mesenchymal non-adenomatous. Features include distorted and dilated crypts surrounded by a prominent inflamed stroma, with hyperplastic regenerative epithelial changes and hypervascularisation. The stroma is described as cellular with bland fibroblastic cells.

Risk factors of delayed post-polypectomy bleeding after treatment of gastrointestinal polyps with snare-assisted endoscopic sub-mucosal dissection.

Gastrointestinal polyps are common gastrointestinal diseases that involve localised hyperplastic masses derived from gastrointestinal mucosa. To investigate the risk factors of delayed post-polypectomy bleeding (DPPB) after the treatment of gastrointestinal polyps with snare-assisted endoscopic sub-mucosal dissection (ESD) and to construct a nomogram model to predict the risk of DPPB. A total of 226 patients who underwent snare-assisted ESD for gastrointestinal polyps from May 2018 to November 2020 were divided into DPPB group (n = 10) and non-DPPB group (n = 216). The correlations of clinical data and endoscopic data with DPPB were compared. Univariate analysis was performed to screen the influencing factors of DPPB. Multivariate logistic regression analysis was used to screen the risk factors of DPPB, which was employed to construct a nomogram prediction model. SPSS 16.0 software was utilised for statistical analysis. Numerical data were expressed as percentage (n [%]), and Chi-square test was performed for univariate analysis. The significant factors (P < 0.05) in univariate analysis were included in multivariate logistic regression analysis, and the variables with statistical significance (P < 0.05) were considered as independent risk factors. The factors were used to construct a nomogram model for predicting the risk of DPPB. Bootstrap method was employed to perform repeated sampling 1000 times for internal verification. The consistency index (C-index) was used to evaluate the discrimination of the model, and C-index ≥0.70 represented a good discrimination. Two-tailed P < 0.05 indicated that a difference was statistically significant. Univariate and multivariate logistic regression analyses revealed that hypertension, polyp location, polyp diameter, polyp morphology and intra-operative bleeding were the independent risk factors for DPPB (P < 0.05). The C-index of the nomogram model for predicting the risk of DPPB was 0.791, indicating a good discrimination. The calibration curve showed that the mean absolute error between predicted and actual DPPB occurrence risks was 0.014, indicating a high accuracy. Hypertension, polyp location, polyp diameter, polyp morphology and intra-operative bleeding are the independent risk factors for DPPB, and the nomogram model established based on these factors for prediction has good discrimination and accuracy. Therefore, it is recommended to perform targeted intervention for high-risk groups to reduce the incidence of DPPB.

GastroNet: Gastrointestinal Polyp and Abnormal Feature Detection and Classification With Deep Learning Approach

GastroNet: Gastrointestinal Polyp and Abnormal Feature Detection and Classification With Deep Learning Approach

Gastrointestinal polyps with atypical presentations: A case series

Gastrointestinal polyps with atypical presentations: A case series

Clinical Efficacy of 755 nm Laser Treatment of Lip Mucosal Pigmentation in Children with Peutz–Jeghers Syndrome

Peutz–Jeghers syndrome (PJS) is a rare genetic disorder characterized by multiple gastrointestinal polyps and mucocutaneous pigmentation. Abnormal pigmentation typically develops in infancy or childhood. As PJS‐related facial pigmentation can lead to psychological burden due to its effects on esthetics, treatment is required. Herein, we report on the efficacy and safety of treatment of lip mucosal pigmentation using a Q‐switched 755 nm Alexandrite Laser in children with PJS, aged 2–12 years of age. A topical anesthetic was used prior to the application of laser therapy. A treatment efficacy of 100% was achieved with one to three treatments, with an excellent outcome achieved in five cases (62.5%) and a good outcome in three (37.5%). Recurrent pigmentation was observed in one case over the 6‐month follow‐up period. There were no adverse effects, such as scarring or hyperpigmentation or hypopigmentation. The treatment did cause pain, apprehension, and crying in some children, requiring special attention. Although our sample size is small, our findings do provide support of the high efficacy and safety of the Q‐switched 755 nm Alexandrite Laser for the treatment of lip mucosal pigmentation in children with PJS. Further studies are required to confirm these findings.

Retracted: Analysis of the Influence of Comprehensive Nursing Intervention on Vital Signs and Negative Emotions of Patients with Gastrointestinal Polyps Treated by Digestive Endoscopy.

[This retracts the article DOI: 10.1155/2022/5931588.].

Intraoperative endoscopy-assisted tumor debulking in pediatric peutz-jeghers syndrome with early onset massive polyp burden phenotype

Peutz-Jeghers Syndrome is an autosomal dominant disorder linked to abnormalities in STK11, and is associated with mucocutaneous pigmentation, sex cord tumors, and gastrointestinal polyps. While it is extremely rare in children under the age of 2, several cases of profound disease have been documented in this population. Here, we detail a case of Peutz-Jeghers Syndrome presenting initially as intussusception, where massive polyp burden nearly occluded the duodenum of a 15-month-old patient and required multimodal operative intervention. Further, we posit that race-based implicit bias may contribute to delays in care and the identification of patients at risk for rare diseases, particularly with atypical presentation, such as the child highlighted in this case. • Varying genetic anomalies may yield more aggressive expression of Peutz-Jeghers Syndrome. • Variance in phenotypic aggression may require alternative screening models. • Social determinants of health and disparities should be considered in screening guidelines.

HD2A-Net: A novel dual gated attention network using comprehensive hybrid dilated convolutions for medical image segmentation

The convolutional neural networks (CNNs) have been widely proposed in the medical image analysis tasks, especially in the image segmentations. In recent years, the encoder–decoder structures, such as the U-Net, were rendered. However, the multi-scale information transmission and effective modeling for long-range feature dependencies in these structures were not sufficiently considered. To improve the performance of the existing methods, we propose a novel hybrid dual dilated attention network (HD2A-Net) to conduct the lesion region segmentations. In the proposed network, we innovatively present the comprehensive hybrid dilated convolution (CHDC) module, which facilitates the transmission of the multi-scale information. Based on the CHDC module and the attention mechanisms, we design a novel dual dilated gated attention (DDGA) block to enhance the saliency of related regions from the multi-scale aspect. Besides, a dilated dense (DD) block is designed to expand the receptive fields. The ablation studies were performed to verify our proposed blocks. Besides, the interpretability of the HD2A-Net was analyzed through the visualization of the attention weight maps from the key blocks. Compared to the state-of-the-art methods including CA-Net, DeepLabV3+, and Attention U-Net, the HD2A-Net outperforms significantly, with the metrics of Dice, Average Symmetric Surface Distance (ASSD), and mean Intersection-over-Union (mIoU) reaching 93.16%, 93.63%, and 94.72%, 0.36 pix, 0.69 pix, and 0.52 pix, and 88.03%, 88.67%, and 90.33% on three publicly available medical image datasets: MAEDE-MAFTOUNI (COVID-19 CT), ISIC-2018 (Melanoma Dermoscopy), and Kvasir-SEG (Gastrointestinal Disease Polyp), respectively.

20-year experience of treating esophageal polyps in children

Introduction. Gastrointestinal polyps are rare in newborn children, at the same time they are most common in children aged 2 to 10 years. Many aspects of endoscopic surgical treatment of polyps in children remain controversial, since they are not sufficiently covered in domestic and foreign literature.The aim was to conduct a retrospective analysis of surgical treatment of abdominal polyps of the esophagus in 52 children in the surgical and endoscopic department of the Regional Children's Clinical Hospital of Rostov-on-Don.Material and methods. For a 20-year period (2001-2020) and presentation of own material for the treatment of children with esophageal polyps based on modern pathogenetic views on the occurrence and development of this pathology. The main symptom of the disease in patients was dysphagia, which occurred in 79% of patients. Under anesthesia in the operating unit, patients underwent endoscopic polypectomy using diathermocoagulation, followed by covering the defect of the esophageal wall by clipping the edges of the mucous membrane.Results. The authors found that it is sufficient to perform polyp removal within the unaffected areas and continue antireflux therapy in order to get a full recovery of patients. Polyps of the transition zone between the esophagus and the stomach seem to have, among other things, also a morphological cause of their origin and development.The contact of two types of mucous membranes (esophagus and stomach) suggests, under certain conditions, the possibility of the development of polyps at the junction of two different morphological structure of mucous membranes. The benign nature of the polyps was confirmed histologically.Conclusion. The authors found that in the treatment of juvenile esophageal polyps, the suppression of gastroesophageal reflux disease should be considered mandatory both before and after surgery. There were no relapses of the disease.

Association of gallbladder diseases with risk of gastrointestinal polyps

BackgroundIt has not yet been determined whether gastroscopy and colonoscopy screening help patients with gallbladder diseases. We aim to retrospectively investigate the relationship between gallbladder diseases and gastrointestinal polyps in order to provide a theoretical basis for the early screening of gastrointestinal polyps in patients with gallbladder disease.MethodsThis is a retrospective cross-sectional study involving 1662 patients who underwent gastroscopy, colonoscopy, and abdominal ultrasound as part of their health check-up from January 2015 to July 2020. We also compared the patients with and without gallbladder diseases to determine the prevalence of gastrointestinal polyps.ResultsPatients with gallbladder polyps had greater odds of having colorectal polyps (adjusted odds ratio (OR)=1.77, 95% confidence interval [Cl]: 1.23 to 2.54, p=0.002) and gastric plus colorectal polyps (adjusted OR=2.94, 95%Cl: 1.62 to 5.32, p<0.001) than those without. Patients with multiple gallbladder polyps had greater odds of having colorectal polyps (adjusted OR=2.33, 95% CI: 1.33 to 4.07, p=0.003) and gastric plus colorectal polyps (adjusted OR=3.95, 95% CI: 1.72 to 9.11, p=0.001), and patients with gallbladder polyps had greater odds of having left-colon polyps (adjusted OR=1.90, 95% CI: 1.25 to 2.88, p=0.003) and colorectal adenoma (adjusted OR=1.78, 95% CI: 1.19 to 2.66, p=0.005). We also noted that women with gallbladder polyps had a higher prevalence of colorectal polyps (OR=2.13, 95% CI: 1.20 to 3.77, p=0.010) and gastric plus colorectal polyps (OR=3.69, 95% CI: 1.58 to 8.62, p=0.003). However, no positive correlation was observed between gallbladder stones and gastrointestinal polyps.ConclusionsGallbladder polyps are significant indicators of colorectal and gastric plus colorectal polyps. Hence, gastroscopy and colonoscopy screening should be performed for patients with gallbladder polyps, particularly female patients and those with multiple gallbladder polyps.

Enhanced segmentation of gastrointestinal polyps from capsule endoscopy images with artifacts using ensemble learning.

Endoscopy artifacts are widespread in real capsule endoscopy (CE) images but not in high-quality standard datasets. To improve the segmentation performance of polyps from CE images with artifacts based on ensemble learning. We collected 277 polyp images with CE artifacts from 5760 h of videos from 480 patients at Guangzhou First People's Hospital from January 2016 to December 2019. Two public high-quality standard external datasets were retrieved and used for the comparison experiments. For each dataset, we randomly segmented the data into training, validation, and testing sets for model training, selection, and testing. We compared the performance of the base models and the ensemble model in segmenting polyps from images with artifacts. The performance of the semantic segmentation model was affected by artifacts in the sample images, which also affected the results of polyp detection by CE using a single model. The evaluation based on real datasets with artifacts and standard datasets showed that the ensemble model of all state-of-the-art models performed better than the best corresponding base learner on the real dataset with artifacts. Compared with the corresponding optimal base learners, the intersection over union (IoU) and dice of the ensemble learning model increased to different degrees, ranging from 0.08% to 7.01% and 0.61% to 4.93%, respectively. Moreover, in the standard datasets without artifacts, most of the ensemble models were slightly better than the base learner, as demonstrated by the IoU and dice increases ranging from -0.28% to 1.20% and -0.61% to 0.76%, respectively. Ensemble learning can improve the segmentation accuracy of polyps from CE images with artifacts. Our results demonstrated an improvement in the detection rate of polyps with interference from artifacts.

Clinical, endoscopic features and histopathology classification of gastrointestinal polyps

Background: Gastrointestinal polyps are common, proliferative or neoplastic mucosal lesions protruding into the lumen of the digestive tract. Gastrointestinal polyps are considered to be precursors to cancer development. Therefore, the cancer potential can be reduced to a great extent by early detection and removal of polyps. Clinical symptoms of the disease are often poor and unclear so early detection and diagnosis are definitely based on endoscopy and especially histopathology to classify and evaluate benign or malignant potential of polyps. Objectives: 1. To describe some clinical and endoscopic features of gastrointestinal polyps. 2. To diagnose and classify histopathological types of gastrointestinal polyps, evaluate the correlation of some endoscopic features and histopathology. Materials and Methods: Cross-sectional research on 77 patients diagnosed by Endoscopy and histopathology at the Hospital of Hue University of Medicine and Pharmacy from 02.2020 to 01.2022. Results: Gastrointestinal polyps were common in patients ≥ 60 years (49.4%), the ratio of male/female was 1.4. Common reasons for hospital admission: abdominal pain (33.8%), hematochezia (31.2%). Common symptoms: abdominal pain 62.5%, hematochezia 35.1%. The majority of polyps were located in the colorectal at a rate of 89.6%. Number of polyps per patient: Single polyp (66.2%), multiple polyps (33.8%), no polyposis case. Polyps usually have the characteristics: peduncle (66.2%), clear boundary (80.5%), smooth surface (71.4%). Size of polyps: &lt; 1 cm (74%), &gt; 2 cm were very rare, accounting for 2.6%. Histopathological results showed that adenoma and hyperplasia polyps accounted for the highest proportion, respectively 46.8% and 40.3%. Level of dysplasia: no dysplasia (48%), low grade dysplasia (37.7%) and high grade dysplasia (14.3%). Adenocarcinoma polyps accounted for 5.2% (4 patients), of which 2 patients had carcinoma in situ and 2 patients with invasive adenocarcinoma. There was no statistically significant difference between the endoscopic features and the histopathological results. Conclusion: Endoscopy is a common and effective means to detect gastrointestinal polyps. However, the nature of these polyps has yet to be confirmed, especially the high risk ones of malignancy. For this reason, a biopsy or excision of the polyp is necessary for histopathology Key words: Gastrointestinal polyps, endoscopy, histopathology.

Investigation of Usability of Artificial Intelligence Semantic Video Processing Methods in Medicine

Aim: The goal of this study is to produce user-friendly software for healthcare professionals with various approaches such as detection, identification, classification, and tracking of polyps contained in endoscopic images utilizing appropriate video/image processing techniques and CNN architecture. &#x0D; Material and Method: There were 345 photos in total in the study. These photographs are images depicting anatomical milestones, clinical findings, or gastrointestinal procedures in the digestive tract that have been documented and validated by medical specialists (skilled endoscopists). Each class has hundreds of images. The photos were downloaded from https://datasets.simula.no/kvasir, which is a free source for educational and research purposes. In the modeling phase, CNN and the Max-Margin object detection technique (MMOD), one of the deep neural network designs in the Dlib package, were employed. The data set was separated as 80% training and 20% test dataset using the simple cross-validation method (hold-out). Precision, recall, F1-score, average precision (AP), mean average precision (mAP), ideal localization recall precision (oLRP), mean optimal LRP (moLRP), and intersection over union (IoU) were used to evaluate model performance.&#x0D; Results: When the previously described steps were performed on the open-access video image dataset of endoscopic polyps in the current study, all performance metrics examined in the training dataset received a value of 1, whereas, in the test dataset precision, sensitivity, F1-score, AP, mAP, oLRP, and moLRP were 98%, 90%, 94%, 89%, 89%, 48%, and 48% respectively.&#x0D; Conclusion: The proposed approach was found to make accurate predictions in the diagnosis of gastrointestinal polyps based on the values of the calculated performance criteria.