Gastric polyps (GP) are a serious clinical problem due to the high prevalence and tendency to malignant transformation with nonspecifi c symptoms. The literature does not describe clinical and anamnestic markers that make it possible to suspect the presence of GP, and tactics for the management of patients with GP are not proposed. Aim : a study the clinical, anamnestic features of patients with GP, infection with Helicobacter pylori . Materials and methods : 61 patients with hyperplastic GP (HGP) and 41 with adenomatous GP (AGP) were examined. We conducted a general clinical study of patients’ complaints, also clarifi ed the duration and features of the course of the disease, the association with Helicobacter pylori (HP), endoscopic and ultrasound examination of abdominal organs. Results : the clinical manifestations of GP are nonspecifi c: non-intense epigastric pain after eating or without connection with food intake, a combination of dyspeptic hyperacid complaints (heartburn) and dyskinetic (nausea, belching with air) character. Symptoms of chronic atrophic gastritis are typical for HGP. There was a high family burden on oncopathology — 21.4% of patients, one in ten had a burdened hereditary history of stomach cancer. In the group of HGP, polyps of other gastrointestinal tract localizations were detected in almost 40% of cases, with AGP in more than half — 25 (61%). Colon polyps and gallbladder polyps were detected in a quarter of patients with AGP. HP infection was detected in GP in more than half of the patients. Conclusion : patients with chronic atrophic gastritis, cholelithiasis and pathology of the biliary tract, polyps of other localization, burdened with hereditary oncopathology, should be considered at risk of detection of GP. All patients with GP are shown a follow-up examination to detect chronic atrophic gastritis, patology of the biliary tract, polyps and neoplasms.