Gastric Flap Research Articles

EXPERIMENTAL USE OF A GASTRIC FLAP ON AN OMENTAL PEDICLE TO CLOSE DEFECTS IN THE TRACHEA, PHARYNX, OR CERVICAL ESOPHAGUS

The use of local or regional skin flaps for repairs after head and neck cancer surgery often increases the deformity of the patient. We present a new procedure using a gastric flap on an omental pedicle. It has been successful in dog experiments where we transferred it to the head and neck region, to serve as a substitute for the standard skin flaps.

A reversed jejunal segment interposition as feeding gastrostomy.

Permanent feeding gastrostomies are needed for prolonged alimentation in some patients with foregut obstruction. The usual gastric flap or tube may be limited in patients with previous gastric surgery or with a small stomach. In these patients, interposition of a short, vascularized jejunal segment between the anterior wall of the stomach and the outside may be valuable. Periodic intubation is easy. Tested initially in dogs and then applied to selected patients, we have not seen ulcers, regurgitation, soiling, pain, or other complications.

Paper electrophoretic study of protein-losing secretions from explanted gastric mucosa in rats.

Summary and conclusionsGastric secretions were collected from the stomachs of rats with ligated cardia and pylorus and from the explanted gastric flaps of male rats. Explantation of gastric flaps in male rats results in atrophy of the superficial elements of the gastric glands, obliteration of glandular ducts by overgrowth of cuboidal surface epithelium, and fibrosis and superficial ulceration of the explanted mucosa.The absence of all glandular components of gastric juice from the secretion of the explants, as previously reported by other workers. was confirmed. This was true of HCl, pepsin, ‘cathepsin’ and ‘glandular mucoprotein’ and their electrophoretic correlates, components P and M1, as well as of the cathodic component X2. Conversely, the presence of gastric mucoproteose and, on paper electrophoresis, the corresponding electrophoretic band M3, confirms the surface epithelial origin of these materials. The electrophoretic patterns of secretions from explanted gastric mucosa are similar to those obse...

Limitations of the Use of Indicators for Determination of Acidity in the Gastric Lumina

Hydrogen ion indicators were injected intravenously in dogs with an actively secreting exteriorized gastric flap. The flap was frozen, sectioned and observed microscopically at –18°C. Only neutral red and Prussian blue were seen microscopically in the lumina and then only when the secretory rate was depressed to essentially zero. Control experiments revealed that the indicators, when in true solution and in concentrations equal to the maximum obtained in gastric juice, cannot be seen microscopically when examined through depths comparable to the diameters of the lumina. They can be seen when precipitated or adsorbed to particulate matter. The implications of these findings with respect to the problem of the pH of the lumina are discussed.