Gastric Duplication Cyst Research Articles

Prenatal diagnosis of gastric duplication cyst at the fundus

A male infant was born via normal spontaneous delivery at 39+4 weeks of gestation with a birth weight of 3135 g by a G2P0A0 mother. A spherical anechoic lesion (1.5 cm) abutting the gastric fundus was found on prenatal ultrasonography at 29+4 weeks of gestation. This cystic mass exhibited an indistinct “double-wall” sign with a hyperechoic inner layer and hypoechoic outer layer (Fig. 1A). For further differentiation of duplication, splenic, or suprarenal cysts, magnetic resonance imaging (MRI) was performed using a 1.5 T scanner at 30+5 weeks of gestation.

Pancreatic ductal adenocarcinoma in a patient with pancreas divisum and gastrointestinal duplication cyst: a case report

BackgroundThe complication of duplication of alimentary tracts and pancreas divisum (PD) is a rare malformation and the development of pancreatic ductal adenocarcinoma (PDAC) in this malformation is also extremely rare. There have been some reports of complication of malignancy in a gastric duplication cyst (GDC) and PD. However, there have been no reports of complication of PDAC in cases with GDC and PD.Case presentationA 54-year-old woman was followed up at the previous hospital due to a history of ovarian endometrial adenocarcinoma. She also had a surgical history of partial excision for a GDC and pancreatic tail of PD in her childhood. A gynecological follow-up computed tomography (CT) examination revealed the pancreatic body tumor and the bifurcated main pancreatic duct dilatation. Furthermore, magnetic resonance cholangiopancreatography also revealed that the ventral main pancreatic duct communicated with the GDC. The initial levels of tumor markers were high, but we could not achieve preoperative histopathological diagnosis. The preoperative diagnosis was PDAC occurring in a case with PD and GDC. She received two courses of neoadjuvant chemotherapy with gemcitabine and nab-paclitaxel. A CT examination after neoadjuvant chemotherapy revealed the shrinkage of the tumor, and then we performed distal pancreatectomy with splenectomy and GDC resection. A histopathological examination revealed invasive PDAC and lymph node metastases; pathological staging was T1N1M0, stage III. Furthermore, PD and GDC were also histopathologically detected. The postoperative course was uneventful, and she was discharged on the postoperative day 25. She received S-1 monotherapy for 6 months, and no recurrence has been detected at 1 year after radical resection.ConclusionsWe herein presented an extremely rare combined case of PD, GDC and PDAC. We successfully treated it by neoadjuvant chemotherapy and distal pancreatectomy with GDC resection, and postoperative chemotherapy.

Endoscopic resection of a complex gastric duplication cyst using a submucosal tunneling technique.

Endoscopic resection of a complex gastric duplication cyst using a submucosal tunneling technique.

A retroperitoneal supra-adrenal non-communicating gastric duplication cyst: a case report and comprehensive literature review

BackgroundGastric duplication cyst is a rare congenital anomaly. It is usually located in close proximity to the stomach. Nevertheless, there have been seldom reports in the literature that describe unusual locations. Retroperitoneal gastric duplications cysts are extremely rare and are usually confused with renal or adrenal cysts.Case presentationIn this case report, we are presenting a 2-year-old girl with a complaint of bouts of abdominal pain, found to have a retroperitoneal supra-adrenal cyst on imaging. She underwent laparoscopic resection of the cyst with uneventful post-operative course. The histopathological diagnosis was surprisingly gastric duplication cyst.ConclusionIn our review of the literature, the variability of this condition and its clinical manifestation are apparent. We also conclude that this diagnostic entity should be part of the differential diagnosis of intraperitoneal or retroperitoneal cysts and that laparoscopic resection of retroperitoneal cysts is the preferred approach.

Gastrik Duplikasyon Kisti: Ender Bir Olgu Sunum

Duplication cysts are developmental anomalies of gastrointestinal tract that can occur at any level from the oral cavity to the rectum, and are extremely rare in the stomach. Most patients show symptom and findings in the first year of life. The most common symptom and findings are abdominal pain, nausea, vomiting, anemia, weight loss and palpable mass. In this study, a gastric duplication cyst was presented in an 11-month-old patient.

Adenocarcinoma Arising From a Gastric Duplication Cyst With Lymph Node Metastasis

Gastric duplication cysts (GDCs) are a relatively rare congenital anomalies and are mostly diagnosed in the early years of life. Herein, we report a very rare surgical case of adenocarcinoma arising from a GDC with lymph node metastasis. A 78-year-old woman was referred to our hospital because of elevated serum levels of cancer antigen (CA) 19-9. Endoscopic ultrasound, contrast fistulography, and computed tomography showed a cystic lesion communicating with the lesser curvature of the stomach. The serum levels of CA 19-9 were high, and fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) imaging demonstrated a slightly enlarged lymph node with high FDG uptake after four months. The size of the cyst was unchanged. It was diagnosed as a GDC. The enlarged lymph node was highly likely to be malignant. Hence, we performed a distal gastrectomy involving the origin of entry and whole body of the GDC with en bloc regional lymphadenectomy. The postoperative pathology was consistent with GDC with moderately differentiated adenocarcinoma and lymph node metastasis. Adjuvant chemotherapy with tegafur-gimeracil-oteracil potassium (S-1) was administered for 12 months. At present, the patient is alive, with no recurrence of the lesion even four years after the operation. GDCs in adults are rare and may predispose to malignancy. Early diagnosis and prompt surgical intervention are important for favorable outcomes.

A Rare Case of Multiple Gastric Duplication Cysts in an Adult

A Rare Case of Multiple Gastric Duplication Cysts in an Adult

Complicated gastric duplication cyst presenting as cystic intraperitoneal collection: a case report

BackgroundAlimentary tract duplications are rare anomalies and any delay in the diagnosis may develop various complications. Infection, hemorrhage, or perforation of the duplication cyst may lead to an acute presentation. Occasionally, it may lead to a diagnostic and management dilemma. Herein, we report an unusual complication of gastric duplication cyst.Case presentationA 2.5-year-old girl presented with recurrent abdominal distension, fever, and abdominal pain. The imaging workup revealed a huge intraperitoneal collection. Intraoperatively, a huge pseudocyst was encountered communicating with the gastric duplication cyst. The gastric duplication cyst was sharing a common wall with the greater curvature of the stomach but was not communicating with the gastric lumen. Pseudocyst along with gastric duplication cyst was completely excised. The resultant seromuscular defect of the stomach was also closed. The postoperative period was uneventful.ConclusionPerforation of the gastric duplication cyst should be kept in differentials of intraperitoneal collection not amenable to multiple aspirations. Huge intraperitoneal collection secondary to perforation of gastric duplication is exceedingly rare and scarcely reported in the literature.

Gastric duplication cyst with localization in the pancreas in children

Introduction. Gastric duplication cyst is a rare clinical observation. More often, these cysts are localized in the fundus or body of the stomach and have a common muscle layers and blood supply. Even more rarely, duplication cysts are not anatomically connected to the stomach and are located in other parts of the abdominal cavity or in the retroperitoneal space. Cystic duplication of the gastrointestinal tract, which are localized in the pancreas, is extremely rare.
 The aim of the study is to demonstrate the possibility of using laparoscopy for this disease.
 Materials and methods. The paper describes three rare clinical observations of gastric duplication cyst topographically associated with the pancreas. In the first clinical observation, gastric duplication cyst was combined with mediastinal duplication cysts, an esophageal bronchial fistula, and extralobar pulmonary sequestrations. In the second observation, a duplication cyst had communication with the pancreatic duct system and was clinically manifested by recurrent bleeding. In the third case, a duplication cyst is diagnosed behind the body and tail of the pancreas.
 Results. In all cases, surgical treatment was carried out by the laparoscopic method, leading to complete recovery. Histological examination in all the described observations confirmed the gastric type of epithelium of the mucous membrane of the cysts. The article provides a review of the literature.
 Conclusion. Thus, the efficiency of laparoscopic interventions in children with gastric duplications topographically associated with the pancreas was demonstrated. The described rare clinical manifestations, a combination of defects, as well as the possible presence of heterotopy of the mucous membrane of the duplication cyst confirm the need for surgical correction of the disease.

Pyloric Obstruction Secondary to a Gastric Duplication Cyst

Pyloric Obstruction Secondary to a Gastric Duplication Cyst

Endoscopic submucosal dissection for gastric duplication cyst with heterotopic pancreas

Endoscopic submucosal dissection for gastric duplication cyst with heterotopic pancreas

Acute inflammation of gastric duplication cyst in a toddler

Gastric duplication cysts (GDC) are rare types of gastrointestinal tract duplications, with various clinical presentations described in the literature. We herein report a 15 months old male toddler who presented to the emergency department with an acute abdomen and septic shock. After initial resuscitation, an upper gastrointestinal contrast study was done and showed a filling defect at the great gastric curvature. Surgical exploration revealed an inflamed gastric duplication cyst which was excised completely. This is a rare presentation of GDC. Accurate diagnosis of these cysts before resection is important. The clinical picture, diagnosis, and management options are described and compared to findings in the literature. In our best knowledge, this is the first case of gastric duplication which presents for the first time with inflammation in a toddler.

Gastric duplication cyst in an infant: A case report

Abstract Gastrointestinal duplication is an infrequent congenital disorder, presenting a mucosal-covered muscle layer. Gastric duplication cysts comprise about 2–9% of all gastrointestinal duplication cysts. The clinical picture is usually characterized by epigastric pain, vomiting and palpable abdominal mass, which may present in other more frequent diseases. Diagnostic confirmation often requires complementary imaging exams and treatment is always surgical. We report the case of a 2 month-old girl, presenting with incoercible, non-bilious vomiting after feeding with an initial diagnosis of hypertrophic pyloric stenosis. After a more thorough investigation, she was diagnosed with a gastric duplication cyst in the pylorus region. A laparotomy was performed with complete cystic resection. The followup visits were uneventful with complete resolution of symptoms. Gastric duplication have less than 50 reported cases. When it is located in the pylorus, it presents with earlier symptoms, including in the neonatal period, simulating cases of pyloric hypertrophic stenosis, as in the case reported here. Clinical examination and imaging help to determine the most accurate diagnosis, allowing appropriate surgical treatment, avoiding future complications including malignant tumors.

Gastric duplication cyst fistulized with the colon in an adult: A case report

AbstractGastric duplication cyst is uncommon congenital malformation rarely seen in the adult population. Although complications related to duplication such as infection, haemorrhage, obstruction, and fistula formation with neighbouring structures had been previously reported, fistulization into the colon in adult has been previously never described to our knowledge. In this study, we present the case of a 36‐year‐old male patient with moderate mental retardation who presented with 10 months history of progressive abdominal pain, nausea, vomiting, and important weight loss. Clinical assessment and radiological investigations demonstrated the presence of non‐communicating gastric duplication cyst inserted on the greater curvature of the antrum and fistulized into the transverse colon. At laparotomy, the cyst was completely excised and the colon containing the fistula was resected with colo‐colonic anastomosis. Pathology confirmed gastric duplication and demonstrated that the inner surface of the cyst was lined by gastric type mucosa. The patient had an uneventful recovery and after 3 months of follow‐up, all symptoms disappeared. Also, he gained 11 kg in weight. This case highlights, therefore, the fact that all gastric duplication cysts should be removed in order to avoid the risk of serious complications.

Gastric duplication cyst with multiple ectopic pancreatic tissues: A case report and review of literature

A gastric duplication cyst (GDC) is a type of enteric duplication cyst. It can co-exist with an ectopic tissue. This was a female toddler with a GDC at the greater curvature. An abdominal ultrasound and a contrast-enhanced computed tomogram suggested the cyst. She had laparotomy, complete cyst and partial gastric excision with the removal of extragastric pancreatic tissue. The histology report came out as a cyst with associated intracystic and an extracystic pancreatic tissue. She made a clinical improvement. GDC can be associated with both intracystic and extracystic ectopic pancreatic tissues. This should be kept in mind when choosing the modality of treatment.

Gastric duplication cyst in an infant presenting with melena

Gastric duplication cyst in an infant presenting with melena

Duodenal atresia type III showing distal bowel gas and atypical malrotation in association with gastric and bile duct duplications

Association of duodenal atresia (DA) with gastric duplication cyst is an extremely rare entity. Furthermore, DA type III with the presence of distal bowel gas is very rare. We report the case of a 13-day-old preterm male with neonatal intestinal obstruction. Radiological evaluation revealed duodenal obstruction at the second part with the presence of few distal bowel gas shadows. Laparotomy revealed dilated gastroduodenum, atypical malrotation, and a cystic structure (duplication cyst) identical to the stomach attached to its greater curvature along with type III atresia of the second part of the duodenum. Duodenotomies revealed the presence of bile along with air at either blind ends of the duodenum which could be explained by the presence of bile duct duplication at the distal end. We propose that this association is due to “defective mesenchyme formation during organogenesis,” which may explain multiple duplication abnormalities and DA.

Gastric outlet obstruction due to gastric duplication cysts with heterotopic pancreatic tissue treated by marsupialization

Abstract Gastric duplication cysts are rare congenital anomalies often treated with complete surgical excision, but this is not always possible. In such cases, resection and reconstruction have been advocated, but this may lead to significant morbidity. We present a unique case of a 3-year old girl who presented with complete gastric outlet obstruction due to multiple gastric duplication cysts with heterotopic pancreatic tissue treated with marsupialization and endoscopic surveillance as an alternative to gastric resection and reconstruction. This approach avoids morbidities from a more extensive procedure and in this case, alleviated the obstruction, averted sequelae secondary to heterotopic pancreatic tissue, and provides surveillance in the rare case of malignant degeneration. The child tolerated the procedure well and has been symptom free for the past year.

Gastric duplication cyst with internal hemorrhage after trauma: A case report and literature review

Gastric duplication cyst with internal hemorrhage after trauma: A case report and literature review

A case of gastric duplication presenting as a retroperitoneal cystic lesion

Gastric duplication is a rare congenital anomaly accounting to 4% of all gastrointestinal tract duplications. It is usually diagnosed pre-natally or during infancy. Retroperitoneal gastric duplication is very rare in adult patients. It is generally asymptomatic or presents with non-specific symptoms. The sensitivity of classical imaging modalities for retroperitoneal gastric duplication is weak. Retroperitoneal gastric duplication could be misdiagnosed as other retroperitoneal cystic lesions and it could be definitely diagnosed by typical findings of abdominal enhanced computed tomography (CT) and endoscopic ultrasonography (EUS) plus EUS:guided fine needle aspiration biopsy in gastric duplicated cyst. A female adult patient was diagnosed by an exceptional hospital CT as retroperitoneal cystic lesion and was admitted in our hospital in March 2019. The abdominal enhanced CT in our hospital preoperatively indicated a cystic lesion above the left kidney and the maximum cross section was 9.0 cm×5.2 cm. Lymphocysts and others should be identified and the lesion might be from the stomach. The retroperitoneal gastric duplication was not diagnosed before operation. In the operation laparoscopy revealed the cystic lesion in the retroperitoneum. The pancreas, left adrenal gland, and left kidney were compressed by the cystic lesion. The top of the lesion was connected with the small curvature of the stomach, but it was not communicated with the stomach. The retroperitoneal cystic lesion was completely excised and the surrounding organs were not damaged. The retroperitoneal gastric duplication was clearly diagnosed by the findings in the operation and the pathology of the lesion. The patient was discharged a week after surgery without gastrointestinal and pancreatic injuries. Therefore, the differential diagnosis of retroperitoneal cysts should consider the possibility of retroperitoneal gastric duplication. For patients with typical CT findings or unclear boundaries between the tumor and the stomach wall, gastric duplication could be diagnosed by EUS plus EUS:guided fine needle aspiration biopsy in the cyst. Retroperitoneal gastric duplication cyst could be completely excised by laparoscopy through abdominal cavity and the stomach wall could be completely repaired.