Supercritical water gasification is a promising technology for renewable hydrogen production from high moisture content biomass. This work produces a machine learning surrogate model to predict the Levelised Cost of Hydrogen over a range of biomass compositions, processing capacities, and geographic locations. The model is published to facilitate early-stage economic analysis (doi.org/10.6084/m9.figshare.22811066). A process simulation using the Gibbs reactor provided the training data using 40 biomass compositions, five processing capacities (10–200 m3/h), and three geographic locations (China, Brazil, UK). The levelised costs ranged between 3.81 and 18.72 $/kgH2 across the considered parameter combinations. Heat and electricity integration resulted in low process emissions averaging 0.46 kgCO2eq/GJH2 (China and Brazil), and 0.37 kgCO2eq/GJH2 (UK). Artificial neural networks were most accurate when compared to random forests and support vector regression for the surrogate model during cross-validation, achieving an accuracy of MAPE: <4.6%, RMSE: <0.39, and R2: >0.99 on the test set.