The application of casting technologies in the production of parts and assemblies of small-size gas turbine engines is justified in the paper. The technology of vacuum casting in gypsum molds was tested during the production of an experimental centrifugal compressor of a small-size gas turbine engine. On the basis of a 3D model of the designed centrifugal compressor, computational studies of vacuum casting were carried out and rational parameters of the technological process were determined. Prototypes of the developed centrifugal compressor of a small-size gas turbine engine were made. The results of calculations and the performed technological experiment confirmed the fill rate of the gating form and the absence of short pour. The distribution of shrinkage porosity and cavities corresponds to the design values and is concentrated in the central part of the casting that is subjected to subsequent machining. The area of the blades, disc and sleeve is formed without defects. The use of casting technologies in the production of parts and assemblies of small-size gas turbine engines assures the required quality with a comparatively low price of the finished product, making it possible to achieve the balance between the cost of the technology and the quality of the product made according to this technology.