ABSTRACT During the “12th Five-Year Plan” period (2011–2015), the safety production situation of coal mines in Guizhou province was generally good. The main types of accidents are gas, flood and roof accidents. The average fatalities for each type of accident were 6.2, 6.8 and 1.2, respectively. During the “12th Five-Year Plan” period, 45 gas accidents occurred and 277 people died, accounting for 18.03% and 48.94% of the total accidents, respectively; 10 flood accidents caused 68 deaths, accounting for 4.1% and 12.01% of the total accidents, respectively; 106 roof accidents caused 129 deaths, accounting for 43.44% and 22.79% of the total accidents, respectively. The number of accidents and casualties is decreasing year by year. Compared with 2015 and 2010, the number of accidents and fatalities decreased by 213 and 324, decreased by 96.82% and 95.27%, respectively. The accident rate of state-owned coal mines was relatively high, and the rate of decline was higher than that of private coal mines. After 2012, the accident rate of production mines was lower than that of construction mines, and preventive measures were explained in terms of safety law enforcement, supervision and technology. The research results have certain reference significance for the government supervision departments to strengthen coal mine safety production, and help to take safety precautions to avoid coal mine accidents.