<p>Multimedia learning and development depicts a long-standing challenge for immersive design and regenerative learning in education and industry. Contradictory findings for gaming learning outreach in relation to conventional learning mode seem to turn the learning gameplay challenge into an enduring one. Limited research outcomes exist not only for open innovation (inflow and outflow innovation aspects) but also for global citizenship reflecting sustainability in education and learning game technology, in particular. Therefore, this study rests on exploring open innovation and global citizenship attributes reflecting sustainability in traditional and learning gameplay modes within an IT and Telecom industry setting. We report on 59 Greek employees’ open innovation and global citizenship knowledge, attitudes and skills investigated after-workshop and after-Resilience gaming training in 2023. The attendees perceived the game as more constructive learning and development tool for open innovation and global citizenship capacity compared to conventional learning delivery. Open innovation was connected to aspects of global citizenship (diversity, interpersonal and problem-solving, and seeking knowledge about political/societal issues) that reflect sustainability post-Resilience gaming. Legal male gender and Athens municipality origin were associated with higher open innovation and diversity (element of global citizenship) attributes post-Resilience gameplay. The obtained evidence is discussed alongside theoretical and practical reflection and strands for additional research in learning game open innovation and global citizenship (sustainability) outreach in education and industry.</p>