We present the first application of the weighted skew-spectra to analyze non-Gaussian information in galaxy survey data. Using the tree-level galaxy skew-spectra together with the one-loop power spectrum multipoles, we analyze the Sloan Digital Sky Survey (SDSS)-III Baryon Oscillation Spectroscopic Survey (BOSS) galaxy clustering data, and target our search towards the equilateral bispectrum shape of primordial non-Gaussianity. We use the Effective Field Theory model for the galaxy power spectrum and bispectrum, and account for systematic effects, such as the survey geometry. From our likelihood analysis, we find f NL equil = -34+296 -334 at 68% CL, consistent with previous works, while systematic errors from our treatment of the survey geometry lead to an unreliable estimation of f NL ortho. We further constrain the bias and counterterm parameters, while keeping the cosmology fixed to Planck 2018 values. As a check, we also validate our analysis pipeline using the Nseries simulation suite.
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