We analyze 330 ks of Chandra X-ray imaging and spectra of the nearby, edge-on starburst and Seyfert type 2 galaxy NGC 4945 to measure the hot gas properties along the galactic outflows. We extract and model spectra from 15 regions extending from −0.55 to +0.85 kpc above and below the galactic disk to determine the best-fit parameters and metal abundances. We find that the hot gas temperatures and number densities peak in the central regions and decrease along the outflows. These profiles are inconsistent with a spherical, adiabatically expanding wind model, suggesting the need to include mass loading and/or a nonspherical outflow geometry. We estimate the mass outflow rate of the hot wind to be 1.6 M ⊙ yr−1. Emission from charge exchange is detected in the northern outflow, and we estimate it contributes 12% to the emitted, broadband (0.5–7 keV) X-ray flux.