Future Opportunities Research Articles

The Treatment of a New Entity in Advanced Non-Small Cell Lung Cancer: MET exon 14 Skipping Mutation.

MET (MET Proto-Oncogene, Receptor Tyrosine Kinase) exon 14 skipping mutation represents one of the most common MET alterations, accounting for approximately 1-3% of all mutations in advanced lung adenocarcinomas. While until 2020 no specific treatment was available for this subset of patients, as of today, three MET Tyrosine Kinase Inhibitors (TKIs) are currently approved in this setting, namely capmatinib, tepotinib and savolitinib. This article aims to provide an extensive overview of the current therapeutic standard of care for exon 14 skipped advanced Non-Small Cell Lung Cancer (NSCLC) patients, alongside with mentions of the main future challenges and opportunities. FDA-approved MET-TKIs currently represent the best option for treating exon 14 skipped advanced NSCLC patients, thanks to their excellent efficacy profile, alongside their manageable safety and tolerability. However, we currently lack specific agents to treat patients progressing on capmatinib or tepotinib, due to a limited understanding of the mechanisms underlying both on- and off-target resistance. In this respect, on-target mutations presently constitute the most explored ones from a mechanistic point of view, and type II MET-TKIs are currently under investigation as the most promising agents capable of overcoming the acquired resistance.

Opportunities for Interventional Radiology in Paediatric Oncology

Interventional oncology (IO) has emerged as a pivotal field within interventional radiology (IR), gaining prominence in the past three decades. It has transcended its initial role in cancer care, expanding beyond biopsies and vascular access to offer a spectrum of percutaneous and transarterial procedures, transforming into a curative and palliative discipline. However, implementing IO in children presents distinctive challenges. While the technical aspects of IO procedures mirror those in adults, paediatric cases require specialised considerations. Radiologists must possess an in-depth understanding of the paediatric disease, tailor imaging modalities to the case, discern unique risks, and interpret disease markers specific to children. Notably, paediatric tumour biopsies demand significantly larger tissue samples for genetic sequencing, staging, and prognostication. Paediatric IO also confronts procedural disparities. Tumours in children may be larger relative to body size, necessitating precise radioembolisation dose calculations. The proximity of critical structures in small bodies amplifies the risk of collateral damage. When performing percutaneous ablation and endovascular therapies, these challenges must also be faced so that radiologists can navigate these complex clinical and technical considerations to ensure safe and effective interventions, all while prioritising the well-being of their young patients. This review summarises the current role and future opportunities for IO in paediatric cancer.

Observations of the 2022 September 5 Solar Energetic Particle Event at 15 Solar Radii

On 2022 September 5, Parker Solar Probe (Parker) observed a large solar energetic particle (SEP) event at the unprecedented distance of only 15 R S from the Sun. The observations from the Integrated Science Investigation of the Sun (IS⊙IS) obtained over the course of this event are remarkably rich, and an overview is presented here. IS⊙IS is capable of measuring ions from 20 keV to over 100 MeV nuc−1 and electrons from 30 keV to 6 MeV; here, we primarily focus on the proton and helium measurements above 80 keV. Among the surprising results are evidence of inverse velocity dispersion at energies above 1 MeV during the onset of the event, a sharp decrease in the energetic particle intensities at all energies at the interplanetary shock crossing, and repeated short durations of highly anisotropic sunward flow. Many changes in the SEP intensities, anisotropy, and spectral steepness are coincident with solar wind structure boundaries identified using the Parker solar wind magnetic field and plasma data. However, there are significant changes that are not correlated with any clearly visible solar wind variation. The observations presented here serve as an introduction to a complex event with numerous opportunities for future, more in-depth studies.

Endowing Metal-Organic Coordination Materials with Chiroptical Activity by a Chiral Anion Strategy.

Recently, chiral metal-organic coordination materials have emerged as promising candidates for a wide range of applications in chiroptoelectronics, chiral catalysis, and information encryption, etc. Notably, the chiroptical effect of coordination chromophores makes them appealing for applications such as photodetectors, OLEDs, 3D displays, and bioimaging. The direct synthesis of chiral coordination materials using chiral organic ligands or complexes with metal-centered chirality is very often tedious and costly. In the case of ionic coordination materials, the combination of chiral anions with cationic, achiral coordination compounds through noncovalent interactions may endow molecular materials with desirable chiroptical properties. The use of such a simple chiral strategy has been proven effective in inducing promising circular dichroism and/or circularly polarized luminescence signals. This concept article mainly delves into the latest advances in exploring the efficacy of such a chiral anion strategy for transforming achiral coordination materials into chromophores with superb photo- or electro-chiroptical properties. In particular, ionic small-molecular metal complexes, metal clusters, coordination supramolecular assemblies, and metal-organic frameworks containing chiral anions are discussed. A perspective on the future opportunities on the preparation of chiroptical materials with the chiral anion strategy is also presented.

Local Renal Treatments for Acute Kidney Injury: A Review of Current Progress and Future Translational Opportunities.

Acute kidney injury (AKI) constitutes a significant public health concern, with limited therapeutic options to mitigate injury or expedite recovery. A novel therapeutic approach, local renal treatment, encompassing pharmacotherapy and surgical interventions, has exhibited positive outcomes in AKI management. Peri-renal administration, employing various delivery routes, such as the renal artery, intrarenal, and subcapsular sites, has demonstrated superiority over peripheral intravenous infusion. This review evaluates different drug delivery methods, analyzing their benefits and limitations, and proposes potential improvements. Renal decapsulation, particularly with the availability of minimally invasive techniques, emerges as an effective procedure warranting renewed consideration for AKI treatment. The potential synergistic effects of combined drug delivery and renal decapsulation could further advance AKI therapies. Clinical studies have already begun to leverage the benefits of local renal treatments, and with ongoing technological advancements, these modalities are expected to increasingly outperform systemic intravenous therapy.

Insurance business and social sustainability: A proposal

Sustainability issues are emerging as a major focus for the insurance institutions, who have to face a number of challenges of the immediate future regarding environmental, social and governance (ESG) factors, climate changes, and catastrophic events. Despite this, literature is still scarce. In this vein, our work contributes to the small but growing body of literature on sustainable finance insurances, by providing evidence of the positive role that insurance companies can play in realizing a more sustainable financial system. The study proposes an innovative securitized process, described as a financial cycle oriented to the achievement of the social objective of collective health. Sustainable instruments allow firms, insurance companies and investors to play a proactive role: virtuous companies, attentive to health protection of their employees, could benefit from premium discounts on the costs of insurance coverage for business risks. The analysis demonstrates how the securitization scheme supports projects with economic-social impact, underlining main actors’ roles, challenges, and opportunities for a sustainable future. Findings pave the way for designing new sustainable insurance solutions and have both practical and social implications.

A Review of Robust Machine Scheduling

Robust optimization (RO) has been recognized as an effective means to deal with unanticipated events in highly uncertain and risky environments. This paper systematically reviews two types of emerging RO machine scheduling approaches—robust machine scheduling (R-MS) and distributionally R-MS (DR-MS) methods—which usually offer tractable formulations and analytical results for machine scheduling problems under uncertainty. First, after highlighting the advantages of RO methods over the stochastic approach in terms of tractability and robustness, we use the bibliometric method to analyze the literature related to R-MS/DR-MS problems and classify them from the following aspects: (1) uncertain factors, (2) uncertainty descriptions, (3) robustness criteria, (4) machine environments and (5) solution methods. Second, we discuss the uncertainty descriptions, and the robust feasibility and robust optimality criteria. We further provide a state-of-the-art review of R-MS/DR-MS models in different machine environments and discuss the performance of the R-MS/DR-MS models. Third, we review and discuss the existing exact, approximation, online, and heuristic solution methods for solving R-MS/DR-MS models. Finally, we present future research opportunities in two promising areas: green machine scheduling problems and machine learning-enabled algorithms. <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Note to Practitioners</i> —Machine scheduling plays an essential role in industrial and service systems, such as manufacturing, power generation, transportation and medical systems. However, in practice, scheduling systems usually operate in highly uncertain environments due to noisy measurements, prediction errors, and implementation deviations. To ensure robust feasibility and robust optimality, robust machine scheduling (R-MS) and distributionally R-MS (DR-MS) approaches have been recently proposed to hedge against the uncertainties related to processing time, release time, due date, machine breakdown, etc. This paper provides a comprehensive review of the R-MS/DR-MS models and algorithms in different machine environments from the aspects of uncertainty descriptions, robustness criteria and solution methods. This paper further highlights the challenges of R-MS problems and provides promising and valuable research opportunities in terms of problem formulations and algorithm designs.

Перспективы применения нейронных сетей для процедурной генерации игрового контента в киберспорте

This article provides an overview of research and practices on using neural network technologies in the field of procedural content generation for esports games. The authors explore the history, current approaches to using artificial neural networks in creating game elements, including levels, characters and scenarios, with the aim of enhancing the gaming experience and increasing the uniqueness of the virtual game world. The article covers various aspects of using neural network methods, such as generative models, autoencoders, generative adversarial networks, deep learning, and recurrent neural networks, for creating dynamic and unpredictable content. Examples of the successful implementation of these technologies in popular esports games are discussed, and potential challenges and issues related to applying neural networks in this context are explored. The authors discuss the prospects for the further development of neural network technologies in esports and offer recommendations for their optimal implementation. Overall, the article presents an analysis of the current state and future opportunities for using neural network approaches for procedural content generation in esports scenarios.

A Study on Significant Challenges and Future Opportunities of Small Scale Firms towards Indian Economic Growth

Small scale firm are the limited scope enterprises and crucial to the advancement of a country. It represents over 40% of the gross modern worth added of the Indian economy. Because of its low capital force and high work retention, the SSI area has contributed altogether to work age and provincial industrialization. With the changing monetary climate, SSIs need to manage various difficulties like huge populace, far reaching joblessness and underemployment, and absence of capital assets, among others. Accordingly, the public authority has given specific explicit offices through different arrangements and projects to tackle the issues and support the development and advancement of little organizations. The business has been very energetic and dynamic throughout recent many years. It has come to the front in the financial development of the country. This area frequently had positive development patterns, in any event, when different areas of the economy experienced either negative or ostensible development. It is notable that a flourishing limited scope area is the way to monetary development in a nation like India. Tragically, SSI is confronting various issues that have made it uncompetitive and debilitated. In this specific circumstance, this study attempts to feature the significance of SSI in Indian economy, SSI strategy and hardships of SSI in Indian economy The Small Sale firms include encounters in solidification managerial proficiency and creation of cognizance on economic values of technologies. This paper incriminates the significant challenges and future opportunities of small scale firm. An attempt is made in this paper to focus on the development of Indian economic growth. Key words: Small Scale firm, Growth on SME, Indian Economy, Sustainable development

Literature Review: Exploring the Relationship Between Gender Cognition and Student Academics

In the course of human history, discussion regarding gender differences and sexual roles has never come to an end. In present-day society, cultural influences, together with the “discovered” physiological differences, have contributed to severe gender inequalities and bias that can be perceived in all aspects. Under this distressing situation, education should be an important aspect that must be paid attention to as it is a determining factor of societal development. Based on empirical research, it really should be concerned that the often biased gender cognition may have potentially contributed to educational impairment, for which the disparate attitudes, opinions, and assumptions that people hold about the two genders, based on sufficient empirical research, have strongly influenced students’ academic performance and have further facilitated the formation of inequalities in future learning opportunities, career path, etc.; it is fair to say that these series of connections have gradually formed a negative feedback loop worsening the current inequality situation. This paper will focus primarily on finding the connections between the tendentious beliefs on gender cognition and students’ academics; specifically, empirical research papers regarding how people’s gender cognition may affect different aged students’ academic performance and self-concepts at schools will be reviewed to look for possible relationships.

CARBON CAPTURE AND UTILIZATION (CCU): A REVIEW OF EMERGING APPLICATIONS AND CHALLENGES

As the global community grapples with the urgent need to mitigate the impacts of climate change, Carbon Capture and Utilization (CCU) has emerged as a promising and multifaceted strategy to address carbon emissions. This review paper provides a comprehensive examination of the current state of CCU technologies, focusing on both the emerging applications and the challenges inherent in their implementation. The first section offers an overview of diverse carbon capture methods, ranging from pre-combustion to direct air capture, highlighting key advancements in technologies such as chemical absorption, membrane separation, and adsorption. Subsequently, the paper delves into the various pathways of carbon utilization, exploring applications in the production of fuels, carbon-based materials, and chemical synthesis. Notable breakthroughs in power-to-gas technologies, utilization in construction materials, and industrial applications are discussed in detail. The core of the review is dedicated to unveiling the emerging applications of CCU, with a specific emphasis on its role in agriculture and soil enhancement, integration with renewable energy systems, and collaboration with other industries. The potential economic and environmental benefits of these applications are explored to underscore the transformative impact of CCU on sustainable development. However, the journey towards widespread CCU adoption is not without challenges. This paper identifies and analyzes technical hurdles related to efficiency, scalability, and cost-effectiveness. Additionally, it examines the regulatory, policy, and societal challenges that may hinder the seamless integration of CCU technologies. Case studies of successful CCU projects provide practical insights, emphasizing lessons learned and best practices. The paper concludes by outlining future prospects and opportunities in the field of CCU, emphasizing the need for continued research, development, and international collaboration. It calls for a concerted effort to overcome challenges and harness the full potential of CCU in contributing to global carbon reduction goals. This comprehensive review aims to serve as a valuable resource for researchers, policymakers, and industry professionals involved in climate change mitigation, providing a nuanced understanding of the current landscape, opportunities, and challenges associated with Carbon Capture and Utilization.&#x0D; Keywords: Carbon Capture and Utilization (CCU), Applications, Challenges.

Development and experiences of an internet-based acceptance and commitment training (I-ACT) intervention in ice hockey players: a qualitative feasibility study.

Internet-based psychological interventions have increased the accessibility of evidence-based treatments in clinical psychology but are still an unexplored delivery format in sport psychology research. This study describes the development and evaluates the experiences of an internet-based acceptance and commitment therapy/training (I-ACT) intervention in ice hockey players focusing on performance enhancement and a sustainable sport participation. I-ACT consisted of seven weekly modules and the feasibility of the intervention was investigated using a qualitative research design. Four national level ice hockey players took part of I-ACT and were interviewed about their experiences using a semi-structured protocol. Interview transcripts were analyzed using qualitative content analysis. Findings suggest that the content of I-ACT was comprehensible, relevant, and that it was possible to put the psychological skills into practice. I-ACT was described as helpful to the ice hockey players either in their sport performance or in their life outside of sport. The internet-format was generally perceived as positive, flexible, and a feasible option for delivering psychological interventions in an elite sport context. Some concerns were raised regarding the timing of the intervention at the end of the season, and some players also wished for more time to complete I-ACT. It was also expressed that some of the exercises could have been better adapted for goaltenders. Further trials are needed to evaluate the effects of I-ACT on performance and mental health outcomes in various sport populations using robust quantitative research methodology. Internet-based psychological interventions are a potential future opportunity to make evidence-based practices more accessible for athletes.

Bifunctional Electrocatalysts for Overall and Hybrid Water Splitting.

Electrocatalytic water splitting driven by renewable electricity has been recognized as a promising approach for green hydrogen production. Different from conventional strategies in developing electrocatalysts for the two half-reactions of water splitting (e.g., the hydrogen and oxygen evolution reactions, HER and OER) separately, there has been a growing interest in designing and developing bifunctional electrocatalysts, which are able to catalyze both the HER and OER. In addition, considering the high overpotentials required for OER while limited value of the produced oxygen, there is another rapidly growing interest in exploring alternative oxidation reactions to replace OER for hybrid water splitting toward energy-efficient hydrogen generation. This Review begins with an introduction on the fundamental aspects of water splitting, followed by a thorough discussion on various physicochemical characterization techniques that are frequently employed in probing the active sites, with an emphasis on the reconstruction of bifunctional electrocatalysts during redox electrolysis. The design, synthesis, and performance of diverse bifunctional electrocatalysts based on noble metals, nonprecious metals, and metal-free nanocarbons, for overall water splitting in acidic and alkaline electrolytes, are thoroughly summarized and compared. Next, their application toward hybrid water splitting is also presented, wherein the alternative anodic reactions include sacrificing agents oxidation, pollutants oxidative degradation, and organics oxidative upgrading. Finally, a concise statement on the current challenges and future opportunities of bifunctional electrocatalysts for both overall and hybrid water splitting is presented in the hope of guiding future endeavors in the quest for energy-efficient and sustainable green hydrogen production.

Advancements and Challenges in Photovoltaic Cell Recycling: A Comprehensive Review

This review examines the complex landscape of photovoltaic (PV) module recycling and outlines the challenges hindering widespread adoption and efficiency. Technological complexities resulting from different module compositions, different recycling processes and economic hurdles are significant barriers. Inadequate infrastructure, regulatory gaps and limited awareness are also hampering progress. In addition, this analysis draws parallels between the development of PV module recycling and recycling technologies for other high-tech products, such as lithium-ion batteries, highlighting similarities in regulatory and technical feasibility challenges. Amid these challenges, however, lie opportunities for a sustainable future. Technological advances, stakeholder collaboration and the adoption of circular economy principles emerge as key ways forward. This review highlights the need for concerted action to overcome barriers and drive the development of efficient and sustainable PV module recycling practices.

The Implementation of Digital Entrepreneurship Learning in Higher Education: A Systematic Literature Review

The phenomenon and topic of digital entrepreneurship learning remain popular for analysis in the era of digitization. Previous literature reviews discussed the context and concept of digital entrepreneurship only. This article presents a literature review aimed at facilitating the search for research publications on digital entrepreneurship, in order to understand the track record, learning models, the impact of implementing digital entrepreneurship learning, and future research opportunities. The article has used the Systematic Literature Review (SLR) method using the Scopus database. This article has used "digital entrepreneurship" keyword for search the resources in January 2014 to May 2023 period. The result of the literature screening process yielded 19 relevant journals. The results of the literature review indicate that research on this topic has shown a significant increase and has the potential to continue to grow. Digital entrepreneurship learning can be designed using experiential learning approaches or the Internet of Things (IoT) and technology approaches. The implementation gives an impact on business opportunities, entrepreneurial intention, innovation, entrepreneurial attitude, and student problem-solving. This study contributes to providing an overview of learning models that can be replicated or modified in future research.&#x0D; Highlights:&#x0D; &#x0D; Growing research on digital entrepreneurship education; impactful learning approaches identified.&#x0D; Experiential and IoT-based methods enhance digital entrepreneurship learning outcomes.&#x0D; Positive impact on business opportunities, innovation, and entrepreneurial skills observed.&#x0D; &#x0D; Keywords: Digital Entrepreneurship, Entrepreneurship Learning, Learning Model

The New Cyberlinktech, Inc. Resilience to Creating Growth Model

The New Cyberlinktech, Inc. (TNCI) operates in a highly dynamic and evolving market, requiring the need for a strategic business plan to sustain growth and adaptability. The New Cyberlinktech, Inc. (TNCI) is one of the leading information technology providers for Private Emission Testing Centers (PETCs) under the Department of Transportation and the Land Transportation Office in the Philippines. TNCI faces significant challenges in the current market landscape, including increasing regulatory pressure against PETCs, the emergence of the Motor Vehicle Inspection System (MVIS) as an alternative mode of vehicle testing, and the frequent leadership changes and abrupt policy shifts at the Land Transportation Office (LTO) and the Department of Transportation (DOTr). To ensure sustainability and adaptability, this dissertation aims to develop a comprehensive business plan for The New Cyberlinktech, Inc. (TNCI) that addresses the challenges posed by the rapidly changing market landscape including a 5-year roadmap. The research design employs a mixed methods approach. The qualitative phase involves conducting interviews with key stakeholders within TNCI, including senior management, employees, and selected industry experts. Through these qualitative interactions, the study aims to identify the specific challenges faced by TNCI in the evolving market and explore potential strategic approaches to address them. In the quantitative phase, the focus is on using surveys among the current clients of the company to determine the preferred IT projects that they want the company to implement in the future. The quantitative analysis provides a comprehensive assessment of TNCI’s current performance, identifies potential risks and opportunities, and informs the development of strategic recommendations. The integrated analysis phase synthesizes the findings from the qualitative and quantitative data. By comparing and contrasting the insights gained from both approaches, a holistic understanding of the challenges and opportunities facing TNCI is achieved. The strategic business plan is formulated based on the integrated analysis, considering the specific needs and goals of TNCI. The plan encompasses strategies to address regulatory challenges, navigate the MVIS landscape, manage leadership changes, adapt to policy shifts, and recommend potential IT projects that the company can adapt and implement. Potential findings may include insights into the specific regulatory pressures faced by PETCs, the implications of the MVIS on TNCI’s business model, and strategies to mitigate the effects of leadership and policy changes. The implications of the research findings can inform TNCI’s decision-making process and help guide the company in sustaining growth and adaptability in the rapidly evolving market. This dissertation contributes to the body of knowledge by providing a comprehensive strategic business plan tailored to TNCI’s context. The findings and recommendations have practical implications for TNCI and other IT companies operating in similar environments. Future research opportunities may involve evaluating the implementation and effectiveness of the proposed business plan and exploring additional strategies to enhance TNCI’s competitive advantage in the PETC industry. Keywords: Strategic continuity, Business plan, Sustainability, Adaptability, Private Emission Testing Centers, Motor Vehicle Inspection System, Regulatory pressure, Leadership change, Policy shifts, mixed methods researc

Organizational change towards the circular economy: A systematic review of the literature

AbstractScholars have long studied how organizations can transition towards greater sustainability, but it is only recently that they have begun to investigate a fundamentally new stream in sustainability thinking: the circular economy paradigm. Instead of the ‘make‐use‐dispose’ approach of a linear economy, a circular economy aims at eliminating waste and avoiding damage to the environment by closing resource loops. Given the recent surge of scholarly interest in the ways in which organizations can change towards working in a more circular way, it is important and timely to verify what scholars have learnt, what remains contested, and what should be done next. To this end, we are reviewing literature on the emerging field of ‘Organizational Change towards a Circular Economy’ (OCCE). We identify and analyse research that sits at the interface of organizational change theory and the circular economy paradigm and provide a systematic literature review. Our review reveals consensus, ambiguities, and differences in the OCCE literature along three main dimensions of organizational change (i.e., content, process, and context). Furthermore, we develop a novel and encompassing conceptualization of OCCE as well as outline future research opportunities. Overall, our study brings together the growing but fragmented body of OCCE research and outlines scientific and practical avenues for making progress in a more unified and systematic way.

Two-dimensional (2D) materials for 3D printed micro-supercapacitors and micro-batteries

Two-dimensional (2D) materials display a unique set of physical/chemical properties and are considered potential building blocks for the manufacturing of microstructured materials for a number of applications. Prominent applications range from advanced electronics to miniaturized electrochemical energy storage devices (EESDs). Herein, we present a comprehensive and critical review of the recent developments in design and microfabrication of 2D-driven microscale electrodes for three-dimensional (3D)-printed micro-supercapacitors and micro-batteries. Firstly, we systematically discuss the advantages and disadvantages associated with various microfabrication techniques such as stereolithography, fused deposition modeling, inkjet printing, and direct ink writing. Next, key parameters disclosing the relationship between the characteristics of 2D-based materials and extrusion-driven 3D printing process for the development of versatile and sustainable EESDs are highlighted. 2D materials utilized for the construction of microelectrodes for supercapacitors (e.g., electric double layer capacitors (EDLCs), pseudocapacitors, and hybrid capacitors) and batteries (e.g., Li-based systems and next-generation systems, e.g., sodium-ion batteries and zinc-ion batteries) along with their prominent electrochemical contributions in relation to obtained 3D-printed architectures are discussed in detail. To promote the development of 2D materials-driven high-performance microscale EESDs, the relevant challenges and future research opportunities are also addressed.

A Comparison of Autistic and Non-Autistic College Students' Perceived Challenges and Engagement in Self-Advocacy.

Autistic students experience lower college graduation rates than their peers, affecting future opportunities. Self-advocacy is crucial for successful adaptation in postsecondary settings and is documented as a challenge for autistic students. The purpose of the study was to examine autistic college students' engagement in self-advocacy and specific college-related challenges as compared to their neurodivergent and neurotypical peers. This study used a cross-sectional survey design to compare perceptions related to self-advocacy and college-related challenges across three groups of students: autistic students, students with a disability other than autism, and nondisabled students. Descriptive and inferential statistics were used to compare survey responses across groups. Differences in the groups' perceptions of their engagement in overall self-advocacy and specific self-advocacy strategies were evident. Autistic students rated themselves significantly lower on self-advocacy than did students with other disabilities. When compared to their nondisabled peers, the autistic students and those with other disabilities were less likely to report comfort interacting in the classroom, including less interest in group work, and more difficulty interacting with unfamiliar peers. In addition, the autistic students were more likely to report difficulty recognizing the need for academic assistance when compared to both peer groups. Autistic students also reported greater social challenges in the college setting than their nondisabled peers, and both neurodivergent groups of students reported significantly more challenges, overall, navigating the college setting than did their nondisabled peers. Findings highlight the need for systematic, individualized self-advocacy supports for autistic and other neurodivergent college students. In addition, findings show the need to educate peers and professors about autism and self-advocacy to foster a welcoming college environment. Finally, findings suggest the need for increased social support and opportunities for social integration within postsecondary settings. Speech-language pathologists play a critical role in implementing these next steps.

E-Tattoos: Toward Functional but Imperceptible Interfacing with Human Skin.

The human body continuously emits physiological and psychological information from head to toe. Wearable electronics capable of noninvasively and accurately digitizing this information without compromising user comfort or mobility have the potential to revolutionize telemedicine, mobile health, and both human-machine or human-metaverse interactions. However, state-of-the-art wearable electronics face limitations regarding wearability and functionality due to the mechanical incompatibility between conventional rigid, planar electronics and soft, curvy human skin surfaces. E-Tattoos, a unique type of wearable electronics, are defined by their ultrathin and skin-soft characteristics, which enable noninvasive and comfortable lamination on human skin surfaces without causing obstruction or even mechanical perception. This review article offers an exhaustive exploration of e-tattoos, accounting for their materials, structures, manufacturing processes, properties, functionalities, applications, and remaining challenges. We begin by summarizing the properties of human skin and their effects on signal transmission across the e-tattoo-skin interface. Following this is a discussion of the materials, structural designs, manufacturing, and skin attachment processes of e-tattoos. We classify e-tattoo functionalities into electrical, mechanical, optical, thermal, and chemical sensing, as well as wound healing and other treatments. After discussing energy harvesting and storage capabilities, we outline strategies for the system integration of wireless e-tattoos. In the end, we offer personal perspectives on the remaining challenges and future opportunities in the field.