Future Generations Research Articles

Analyzing meteorological parameters using Pearson correlation coefficient and implementing machine learning models for solar energy prediction in Kuching, Sarawak

Solar energy is one of the clean renewable energy sources that can offset the rising consumption of fossil fuels. However, the meteorological parameters, such as solar irradiance, ambient and solar module temperatures, relative humidity, etc., constantly change, and so does the solar power generation. Such variations cause instability in the power grid operation due to injecting an unpredicted amount of power. Hence, solar energy prediction models capable of learning from past weather data and predicting future energy generation are highly desired for grid operation and planning. The objective of this study is to determine the suitable meteorological parameters for the solar energy prediction model based on the Pearson correlation coefficient and to implement them in different machine learning models. It is found in this study that five meteorological parameters, namely Air temperature, cloud opacity, global tilted irradiance, relative humidity, and zenith angle, correlate highly with solar energy generation. Later, based on the correlations, four machine-learning models were implemented to predict the solar power for Kuching, Sarawak. The accuracy of the models is measured through standard matrices such as root mean square error, mean square error, mean absolute error, and R-squared value.

Can social adversity alter the epigenome, trigger oral disease, and affect future generations?

The nature versus nurture debate has intrigued scientific circles for decades. Although extensive research has established a clear relationship between genetics and disease development, recent evidence has highlighted the insufficiency of attributing adverse health outcomes to genetic factors alone. In fact, it has been suggested that environmental influences, such as socioeconomic position (SEP), may play a much larger role in the development of disease than previously thought, with extensive research suggesting that low SEP is associated with adverse health conditions. In relation to oral health, a higher prevalence of caries (tooth decay) exists among those of low SEP. Although little is known about the biological mechanisms underlying this relationship, epigenetic modifications resulting from environmental influences have been suggested to play an important role. This review explores the intersection of health inequalities and epigenetics, the role of early-life social adversity and its long-term epigenetic impacts, and how those living within the lower hierarchies of the socioeconomic pyramid are indeed at higher risk of developing diseases, particularly in relation to oral health. A deeper understanding of these mechanisms could lead to the development of targeted interventions for individuals of low SEP to improve oral health or identify those who are at higher risk of developing oral disease.

Artificial Intelligence - ai - Present and Future. The New Revolution in Global Informatics; it is for Sure for Future Generations to Engulf and get used to.

Artificial Intelligence - ai - Present and Future. The New Revolution in Global Informatics; it is for Sure for Future Generations to Engulf and get used to.

Exploring memory synchronization and performance considerations for FPGA platform using the high-abstracted OpenCL framework: Benchmarks development and analysis.

A key benefit of the Open Computing Language (OpenCL) software framework is its capability to operate across diverse architectures. Field programmable gate arrays (FPGAs) are a high-speed computing architecture used for computation acceleration. This study investigates the impact of memory access time on overall performance in general FPGA computing environments through the creation of eight benchmarks within the OpenCL framework. The developed benchmarks capture a range of memory access behaviors, and they play a crucial role in assessing the performance of spinning and sleeping on FPGA-based architectures. The results obtained guide the formulation of new implementations and contribute to defining an abstraction of FPGAs. This abstraction is then utilized to create tailored implementations of primitives that are well-suited for this platform. While other research endeavors concentrate on creating benchmarks with the Compute Unified Device Architecture (CUDA) to scrutinize the memory systems across diverse GPU architectures and propose recommendations for future generations of GPU computation platforms, this study delves into the memory system analysis for the broader FPGA computing platform. It achieves this by employing the highly abstracted OpenCL framework, exploring various data workload characteristics, and experimentally delineating the appropriate implementation of primitives that can seamlessly integrate into a design tailored for the FPGA computing platform. Additionally, the results underscore the efficacy of employing a task-parallel model to mitigate the need for high-cost synchronization mechanisms in designs constructed on general FPGA computing platforms.

Regulatory safeguards needed if preimplantation genetic testing for polygenic risk scores (PGT-P) is permitted in Singapore

Singapore, a highly affluent island city-state located in Southeast Asia, has increasingly leveraged new assisted reproductive technologies (ART) to overcome its dismal fertility rates in recent years. A new frontier...

Is problematic use of the Internet and smartphone predictor of unhealthy eating behaviors and abnormal body weight in Turkish young adults?

With technological progress, the use of the internet and smartphones has become an inseparable part of our lives and their use is increasing. The uncontrolled use of both the internet and smartphones is defined as problematic use. This study examined the effects of problematic internet and smartphone use on dietary behaviors and abnormal body weight status in young adults. Participants were 560 university students. Participants completed measures of demographics, dietary behaviors, internet and smartphone usage habits, Young's Internet Addiction Test and Smartphone Addiction Scale. Negative associations were found between dietary behaviors and problematic internet and smartphone use. Significant inverse associations were also found between these uses and recommended consumption levels of several food groups. For a healthy future generation, it is recommended that policies be developed to prevent or manage these problematic uses, especially in young adults with negative dietary behaviors and abnormal body weight.

Environmental Justice Education in Nepal: Policies and Practices

Environmental justice is fundamental to education and policy, ensuring clean environments and sustainable development. The curriculum and constitution of Nepal focus on this, addressing global gaps and encouraging comprehensive wellbeing measures for educational resilience. This paper analyzes how environmental justice is reflected through equitable treatment and meaningful participation of all people in the creation, implementation, and enforcement of environmental laws, regardless of their race, culture, education, and socioeconomic status. To analyze how environmental justice has been enforced in educational policies, interviews were conducted with five policymakers who have long experience in policymaking in the educational sector. The findings revealed that indigenous knowledge, cultural thought, and belief in environmental justice areas were considered major issues in education policies and practices. This study emphasizes the interconnectedness of local and global environmental issues and the need to bridge the gap. The integration of environmental justice in the national curriculum framework highlights the role of local expertise, indigenous knowledge, and practical application. The study recognizes the significance of environmental consciousness, sustainable development, and equal access to education. This study acknowledges constitutional provisions in Nepal supporting environmentally friendly and sustainable development. It emphasizes the importance of environmental education, equitable treatment, and compensation for environmental injustices to safeguard the environment for future generations.

Top predator status and trends: ecological implications, monitoring and mitigation strategies to promote ecosystem-based management

The conservation and management of marine ecosystems hinge on a comprehensive understanding of the status and trends of top predators. This review delves into the ecological significance of marine top predators, examining their roles in maintaining ecosystem stability and functioning through an integrated analysis of current scientific literature. We first assess the efficacy of various monitoring methods, ranging from traditional field observations to cutting-edge technologies like satellite tracking and environmental DNA (eDNA) analysis and evaluating their strengths and limitations in terms of accuracy, spatial coverage, and cost-effectiveness, providing resource managers with essential insights for informed decision-making. Then, by synthesizing data from diverse marine ecosystems, this study offers a comprehensive overview of the trends affecting top predator populations worldwide. We explore the multifaceted impacts of human activities, climate change, and habitat degradation on the abundance and distribution of these key species. In doing so, we shed light on the broader implications of declining top predator populations, such as trophic cascades and altered community structures. Following a thorough assessment of successful strategies for reversing the decline of top predators, a compilation of recommendations is presented, encompassing effective governance interventions. A crucial aspect of effective ecosystem-based management is the implementation of robust monitoring strategies. Mitigation measures are imperative to reverse the adverse impacts on marine top predators. We present a comprehensive array of mitigation options based on successful case studies. These include the establishment of marine protected areas, the enforcement of fisheries regulations, and the promotion of sustainable fishing practices. We deepen the synergies between these strategies and their potential to mitigate human-induced stressors on top predator populations to safeguard their pivotal role in maintaining marine ecosystem structure and function. By examining marine top predators’ ecological significance, analyzing population trends, discussing monitoring techniques, and outlining effective mitigation strategies, we provide a comprehensive resource for researchers, policymakers, and stakeholders engaged in fostering ecosystem-based management approaches. We conclude that integrating these insights into current management frameworks will be essential to safeguard both top predators and the broader marine environment for future generations.

Indigenous Knowledge and Agricultural Practices of Ifugao Ethno-Farming in Ifugao Village, Diffun, Quirino

This study endeavors to delve into the traditional knowledge and farming methods employed by Ifugao farmers residing in Barangay Ifugao Village, Diffun, Quirino. Despite the proven efficacy of Indigenous farming practices, they confront formidable challenges including climate change, biodiversity loss, and the erosion of Indigenous knowledge. The research aims to meticulously document and safeguard the wealth of knowledge and practices upheld by Ifugao farmers, recognizing their pivotal role in fostering environmental sustainability and cultural enrichment. Utilizing an ethnographic approach, this study endeavors to unravel the intricate interplay between farming techniques, traditional wisdom, and the multifaceted challenges posed by modernization. By employing key informant interviews conducted in the Ilocano dialect, the project seeks to elucidate how Ifugao farmers adapt their agricultural practices in response to evolving environmental and socioeconomic dynamics. Through purposive sampling, experienced Ifugao farmers are selected as key informants, ensuring a comprehensive examination of the methods, beliefs, practices, strategies, and knowledge that have underpinned Ifugao ethno-farming traditions. The study, spanning one month and focusing on seasoned Ifugao practitioners, guarantees a thorough exploration of the adaptive measures and customs intrinsic to Ifugao’s agricultural heritage. Reflexive thematic analysis serves as the analytical framework for interpreting the gathered data, with anticipated results offering valuable insights into the resilient techniques employed by Ifugao farmers to preserve their cultural heritage and navigate contemporary challenges. These findings underscore the imperative for collaborative endeavors aimed at safeguarding, documenting, and integrating Indigenous knowledge into agricultural practices, thereby fostering resilience and sustainability for present and future generations. Keywords: Ifugao, Ethno-farming, Indigenous Knowledge, Sustainability, Preservation, Agricultural Practices, Beliefs, Changes perceived, Adaptive Strategies

ASSESSING THE IMPACT OF ENGINEERED WOOD PRODUCTS ON SUSTAINABLE CONSTRUCTION: A COMPARATIVE STUDY WITH CONVENTIONAL CONCRETE BUILDING METHODS

Renewable-sourced EWPs offer enhanced dimensional stability, durability, and mechanical properties, facilitating larger and more complex structural elements, and contributing to faster construction times and better energy performance. The research investigates the feasibility and effectiveness of Engineered Wood Products (EWPs) as sustainable building materials in the construction sector by a comparison of their cost, performance, and environmental impact against conventional concrete. The research emphasises the importance of innovative design, recycling, and waste reduction in fostering sustainable construction methods that satisfy the demands of present and future generations while conserving energy. However, there are negative environmental impacts linked to the production of concrete, such as habitat destruction, atmospheric emissions, and waste generation. The research adopted a web-based survey to gather quantitative data from construction experts. The Relative Importance Index (RII) was adopted to analyze the respondents' perceptions of the benefits of EWP and concrete negative effects. The results of the research reflect respondents' significant preference for EWPs and are consistent with their outstanding environmental qualities. In conclusion, this paper argues that EWPs possess the potential to effectively revolutionise the construction industry by minimising its carbon footprint and encouraging sustainable construction practices that are required for addressing the expectations of both the present and the future.

Towards Sustainable Agriculture: Integrating Agronomic Practices, Environmental Physiology and Plant Nutrition

Sustainable agriculture aims to meet the growing global demand for food without compromising environmental integrity. This review paper explores the integration of agronomic practices, environmental physiology, and plant nutrition as pathways toward sustainable crop production. Intensive agricultural practices have led to significant problems such as soil degradation, loss of biodiversity, and environmental pollution. Recent advancements in plant physiology have enhanced our understanding of plant growth and response to biotic and abiotic stresses. Optimizing crop production in a sustainable manner depends on insights into key processes like photosynthesis, water use efficiency, and nutrient uptake. This review discusses the role of plant growth-promoting microorganisms (PGPMs) as biofertilizers, providing an alternative to harmful agrochemicals. PGPMs can improve soil health and promote plant growth when applied to soil, seeds, or plant surfaces, reducing reliance on synthetic fertilizers and pesticides. Additionally, nanotechnology in agriculture is examined, illustrating how nanomaterials (NMs) and nano-based fertilizers can enhance nutrient absorption and increase crop yields. Beyond these scientific approaches, there is an urgent need to implement novel agricultural practices that support sustainability. The world population is growing at a disquieting rate, placing tremendous pressure on natural resources. This threatens future generations' access to nutritious food and clean air. Innovative approaches like climate-smart agriculture, organic farming, biodynamic agriculture, sustainable intensification, and regenerative agriculture, along with practices such as integrated farming systems, precision agriculture, integrated nutrient management, and integrated pest management, have proven to safeguard agricultural sustainability. By integrating these innovative approaches and practices, it is possible to meet the increasing demands for food while preserving the environment.

The role of financial inclusion, technology innovation, energy and environmental degradation in determining sustainable growth in Asia

AbstractSustainable growth is a top priority for all economies as they work towards creating a prosperous and resilient future for current and future generations. This study empirically explores the important role of financial inclusion (FI), energy consumption, technological (TECH) innovation and environmental degradation in the economic growth of 13 selected developing Asian countries from 2000 to 2021. The feasible generalized least squares method is used for empirical examinations due to the nature of the data. The study focuses on three dimensions of FI: penetration, usage and availability of financial institutions. The results show that FI, energy consumption and TECH innovation encourage economic growth, whereas ecological footprint discourages economic growth in selected Asian countries. The empirical findings highlight the importance of promoting sustainable growth in Asia through enhanced FI, TECH innovation, sustainable energy practices and environmental conservation. Governments in these countries should prioritize strengthening the financial sector, investing in research and development and implementing effective policies to ensure a clean and green environment. This will lead to inclusive and environmentally responsible development that benefits both current and future generations in the region.

Terrestrial Laser Scanning (TLS) Survey and Building Information Modeling (BIM) of The Edmund Pettus Bridge: A Case Study

Abstract. The comprehensive digital documentation of the Edmund Pettus Bridge, a symbol of the American Civil Rights Movement located in Selma, Alabama, serves as an example of integrating Terrestrial Laser Scanning (TLS) and Building Information Modeling (BIM) technologies for the conservation of heritage infrastructure. This study aimed to employ advanced TLS and other Reality Capture (RC) techniques to generate a high-resolution, three-dimensional representation of the bridge, thereby aiding in its structural assessment and preservation. Utilizing TLS alongside 360-degree photography and UAV surveys, the project achieved detailed coverage of the bridge's architectural and structural features. The data collected was processed into a BIM model using Autodesk Revit, offering comprehensive analysis and preservation planning. The findings from this research highlighted previously undetected areas of material degradation and structural vulnerabilities, emphasizing the value of TLS and BIM in revealing critical insights into the condition of heritage structures. This project preserved the digital memory of an iconic Civil Rights landmark and set a framework for applying digital documentation technologies in heritage infrastructure conservation. The success of this methodology offers a valuable precedent for future conservation efforts, showcasing how RC technologies can enhance the preservation of historical sites and ensure their legacy is maintained for future generations.

A human papillomavirus 16 E2-TopBP1 dependent SIRT1-p300 acetylation switch regulates mitotic viral and human protein levels and activates the DNA damage response.

Human papillomaviruses (HPVs) are causative agents in around 5% of all human cancers. While there are prophylactic vaccines that will significantly alleviate HPV disease burden on future generations, there are currently no anti-viral strategies available for the treatment of HPV cancers. To generate such reagents, we must understand more about the HPV life cycle, and in particular about viral-host interactions. Here, we describe a novel mitotic complex generated by the HPV16 E2 protein interacting with the host protein TopBP1 that controls the function of the deacetylase SIRT1. The E2-TopBP1 interaction disrupts SIRT1 function during mitosis in order to enhance acetylation and stability of viral and host proteins. We also demonstrate that the E2-TopBP1 interaction activates the DDR. This novel complex is essential for the HPV16 life cycle and represents a novel anti-viral therapeutic target.

Finding synergies between agroecology and industrial ecology toward sustainable agricultural systems

The question of how humans will co-create better food and agricultural systems is ex­tremely complex, and responses vary significantly due to experiences, worldviews, and values. Those of us working on this question typically agree that the goal is to realize systems that are equitable, just, minimize harm to, and ultimately support healthy ecosystems for current and future generations. I will refer to this goal as sustainability. My training is in industrial ecology and civil and environmental engineering, and my professional research focuses on questions of the climate and nutrient impacts associated with agriculture and food products as they are in our time, i.e., dominated by commodity crops. I was introduced to agroecology about 15 years ago while looking into ways to reduce nutri­ent runoff and improve soil and ecosystems, such as alternative cropping systems, integrated farming practices, permaculture, and more. Eventually, I learned of agroecology as a science, movement, and practice, which increased my interest to learn more. Both industrial ecology and agroecology, and the many branches within them, earnestly pursue facets of sustainability in agriculture, food, and other bio-based systems, and collaboration could lead to synergistic efforts. . . .

A Residential Building Extension Prototype to face Post-Pandemic Needs: Foreseen Challenges and Impacts

The COVID-19 pandemic highlighted the importance of outdoor spaces for maintaining physical and mental well-being. However, many urban residents lack private outdoor areas, which led to harmful health consequences during lockdowns. The research project aims to address and solve this issue by developing a physical/digital prototype called “X-TEND” that extends living space outdoors by attaching it to existing multi-story residential building facades. This prototype intends to promote healthier lifestyles, improving the well-being of individuals and positively impacts the urban surroundings aesthetics. X-TEND prototype uses a light, modular, and prefabricated approach for cost-effectiveness and environmental sustainability. It incorporates generative processes for structural and bioclimatic optimisation complemented by green building strategies to reduce environmental impact while maximising thermal and energy performance. Ultimately, X-TEND prototype contributes to a more sustainable built environment, fostering healthier and more liveable cities for current and future generations.

Assessing the tradeoffs in emissions, air quality and health benefits from excess power generation due to climate-related policies for the transportation sector

As the transportation sector continues to decarbonize through electrification, there is growing interest in quantifying potential tradeoffs in air pollution and health impacts due to potential excess emissions from the power sector. This study investigates air pollution and health impacts of policy-driven changes in the transportation sector and the associated power generation demand in the Northeast and Mid-Atlantic United States. Five illustrative scenarios were designed to capture the effects of different policies under the first mandatory market-based program to reduce greenhouse gases in the US power sector (Regional Greenhouse Gas Initiative—RGGI) and the Transportation and Climate Initiative (TCI). Considering future power generation with new renewable energy investments to meet demands from decarbonized transportation, the scenarios were framed using: 1. 2030 reference cases for both sectors and a hybrid TCI portfolio, 2. Departure from the reference cases defined by Pennsylvania included or not in RGGI, and 3. Power grid emissions estimated under clean energy standard (CES) policy and hybrid TCI portfolio. While the cross-sectoral policy effect on domain-wide concentrations is modest (max ΔPM2.5 ∼ 0.06 μg m3, ΔNO2 ∼ 0.3 ppbv, ΔO3 ∼ 0.15 ppbv), substantial increases in Ohio and West Virginia were attributed to Pennsylvania joining RGGI. With CES enacted and Pennsylvania in RGGI, significant reductions are seen in average concentrations (max ΔPM2.5 ∼ 1.2 μg m3, ΔNO2 ∼ 1.1 ppbv, ΔO3 ∼ 1.7 ppbv) except for Louisiana and Mississippi with corresponding disbenefits. When focusing exclusively on emissions reductions from transportation, the hybrid TCI portfolio had health benefits of 530 avoided adult deaths, and 46 000 avoided asthma exacerbations. With a ‘business as usual’ power grid, these benefits remain comparable and are mainly driven by NO2, followed by PM2.5 and O3. However, if Pennsylvania joins RGGI, total health benefits and spatial distribution change substantially, with a large portion of adverse health impacts moving from TCI states to Ohio and West Virginia. The overall monetized impact of a CES scenario can substantially exceed the estimated average range of 66–69 Billion US$, depending on the interaction with transportation decarbonization strategies and other drivers of exposure.

Desirable Futures: Write Me a Letter

<p>In this special issue, we propose the letter as a form with geographic potential. Building on prior work on letters in geography, Black feminism, and Indigenous studies, we draw on a collection of sixteen letters in the section to build a case for letters as time travel, anticolonial epistemology, feminist geographic method, and worldmaking praxis. We bring together letter writers who speak to their ancestors known and unknown, to future generations, to ideas, to activists, to places, and to strangers—and weave them into a messy and generative conversation on the kinds of spaces that letters make between and among us. Our intention is to build on recent work in geography to experiment with what the letter makes possible for us as geographers.</p><p> </p>

EFFICACY AND SAFETY OF NICORANDIL FOR PERIPROCEDURAL MYOCARDIAL INJURY IN PATIENTS UNDERGOING PCI

Coronary artery disease (CAD) remains a leading cause of morbidity and mortality globally, with percutaneous coronary intervention (PCI) being a typical therapeutic approach. Objectives: In this comparative study, we aimed to investigate the efficacy and safety of nicorandil for periprocedural myocardial injury in patients undergoing PCI. Methods: This comparative study was conducted at Ayub Teaching Hospital from September 2023 to December 2023. Data from 90 patients was recruited for the research using inclusion and exclusion screening standards. Our study was performed on 90 patients treated with percutaneous coronary intervention (PCI). Patients from Group 1 were different from those in Group 2. Group A: the critical study parameters will switch between those patients who received nicorandil and Group B: non-nicorandil patients. Baseline demographic data, past medical history, and relevant laboratory values and clinical characteristics were documented for all patients. In addition, an intraoperative laboratory investigation was conducted, including cardiac biomarkers. Results: Research data were drawn from 90 patients whose gender wasn't a factor based on the research protocol. In Group A, the mean age of the patients was 62 years. Players in group A played for 4 ± 8.5 years. In team B, the players had a slightly longer experience and played for 63. Humans on Earth could do the same, and it could significantly impact future generations: ± 7. 9 years. Of 58 men and 32 women in the control group, there were two persons and persons in the experimental group, respectively. Only one stent differed between the two groups; however, the number was similar. 8 ± 0. 6 mmol/l in the tricorandil group and 1. +9 ± 0 in Case 1. Patients in the Nicorandil group displayed the lowest level of heart problem-causing protein (troponin) at the peak (5. There is a statistically significant 1.8-fold (2 ng/mL versus seven ng/mL) decline in serum lysozyme levels in the group administered rhG-CSF. The treatment group exhibited a substantial increase in haemoglobin levels (t(12) = 3. 74, p-value <0.005) with a mean difference of 0. 5 ± 2 ng/mL. 001, 95% CI: 2. 1 to 3. 5). Conclusion: It is concluded that nicorandil shows positive results for the efficacy (the ability of a drug to bring the desired effect) and safety of the drug in reducing myocardial injury and in maintaining the function of myocardial during percutaneous coronary intervention in patients.

To the Anishinaabeg of the Future

<p>A letter written to future generations of Anishinaabeg expressing my desires for what they can accomplish, and how we can help them get there.</p>