Future Development Research Articles

Exploring the Future of Indoor Navigation: AR Technology

Indoor navigation within complex environments remains a recurring challenge in the age of rapid technological advancement. Traditional methods often fall short when applied to intricate indoor spaces like shopping malls, airports, and corporate campuses. This paper introduces ARNav, an innovative Augmented Reality (AR) based indoor navigation system designed to enhance indoor navigation accuracy and user experience. ARNav utilizes AR technology to overlay digital information, such as arrows, markers, and directional cues, onto the real-time camera view of users' devices. This dynamic overlay simplifies navigation while offering an immersive experience. The system achieves precise indoor positioning through sensor fusion and mapping techniques, boasts an intuitive user-centric design, and implements robust data security measures. Energy efficiency optimization ensures longer battery life, and the system seamlessly integrates with external data sources, offering real-time information on points of interest and events within indoor spaces. A user feedback mechanism allows for continuous improvement, placing user needs at the forefront of development. This paper discusses the design and implementation of ARNav, highlighting the technologies and mathematical models for accurate positioning and AR overlay. ARNav represents a promising solution for indoor wayfinding, combining AR technology with precise indoor navigation to enhance user experiences. The paper explores potential future developments, including advanced AR features, machine learning integration, and compatibility with various devices and platforms, thus contributing to the field of indoor navigation and AR technology.

A soft wearable exoglove for rehabilitation assistance: a novel application of knitted shape-memory alloy as a flexible actuator

We developed the knitted shape-memory alloy (SMA) as a flexible actuator and applied it to a soft wearable exoglove for rehabilitation assistance. Based on user needs and anthropometric data, we custom-designed the exoglove for three hemiplegic patients using the knitted-SMA actuator and evaluated its bending performance, gripping force and wearability under the four simulation conditions (S1–S4). To address the specific needs, both SMA plain- and double-knit modules were applied to the exoglove based on the patients’ finger joint range of motion (ROMs). The joint ROMs of all fingers increased by 13.71% and the skin temperature increased by 2.21 °C after actuating the glove (p = 0.006). The gripping force increased as much as 55.01%, when compared to the baseline. All patients were able to don and doff the developed glove independently, and positively evaluated their subjective satisfaction and thermal perception. The findings suggested the potential of the knitted SMA for the future development of soft wearable robots.

Research progress and future development direction of Alzheimer's therapy

Dementia has become a global crisis, numbering over 50 million people in the world, more than half of whom are Alzheimers disease (AD)s patients. AD is a heterogeneous disease that has complex pathobiologic properties. The exact AD mechanism is unclear at this point, but the pathological hallmarks constitute amyloid- (A) plaques and tau neurofibrillary tangles and most treatments are based on this. AD has a serious impact on society and on humanity, but drugs approved to treat AD are few and ineffective. The article analyzes the possible causes of pathological hallmarks and describes existing treatment options, as well as their shortcomings and potential future treatments. It also speculates on the direction of possible future therapeutic options providing reference for more new technologies and methods of treating AD in the future. However, there are still many unclear pathogenic mechanisms and more effective treatments are needed for further research on AD in the future.

How Constructivist Learning Impacts Secondary Girls’ STEM Career Interests

This is a quantitative study that examines how constructivist learning in a summer camp impacted middle school and high school girls’ STEM knowledge, self-efficacy, and ultimately, their interests in future STEM learning and growth. An online survey was used to collect information from thirty-one girls at the end of a five-week summer camp. The results are mostly confirmative of past studies that used student-centered project-based authentic STEM learning with significant gains in students’ understanding of STEM, self-efficacy, and interests in STEM for future development. The unique contribution of the study, though, is the finding that, when given the opportunity to engage in active learning and problem-solving, girls’ interest in STEM subjects could be substantially boosted; the constructivist learning environment along with their gains in STEM knowledge can compensate any insufficiency in self-efficacy in this regard. This study provides insight about the importance of instructional approach in STEM education.

Nanogenerators: A Strong Backing for Human‐Centered Intelligent Self‐Powered Medical Systems

With the progress of modern biotechnology and people's strong attention to the quality of life and health, intellectualization and individuation have become a new trend of biomedicine development. Nanogenerators which can collect energy from the surrounding environment and convert mechanical energy into electricity become an ideal choice for self‐powered medical systems. In this review article, two types of nanogenerators, friction triboelectric nanogenerators (TENG), and piezoelectric nanogenerators (PENG), which are commonly used in self‐powered medical systems, are mainly introduced. The working mechanism and operation mode of PENG and TENG are introduced, and the mechanism and research progress of human‐centered intelligent self‐powered medical technologies based on PENG and TENG are focused on in the fields of drug delivery, wound healing, treatment for cardiovascular diseases and tumor, neuromodulation, and so on. In addition, also the opportunities and challenges facing the future development of wearable or implanted nanogenerators are introduced. In this review, it is hoped that a comprehensive overview and clarity will be provided for readers committed to self‐powered medical devices.

Envisioning the Future: Nanomicelles Revolutionizing Ocular Drug Delivery.

Due to the complexities of the eye's anatomy and physiology, achieving targeted drug delivery with minimal harm to healthy eye tissues has proven to be difficult. The focus of the review is on the potential of lipid and polymer micelle-based drug delivery systems, specifically nanomicelles, to overcome these challenges and improve the absorption of insoluble drugs. Nanomicelles offer several advantages, such as enhanced drug release kinetics, increased drug incorporation, and improved formulation of hydrophobic medicines. The review provides insights into various excipients, preparation methods, and evaluation techniques used in nanomicellar-based drug delivery systems. Furthermore, the review highlights current research and patents related to nanomicelles in ocular drug delivery, suggesting growing interest and potential for future developments in this field. Nanomicelles present a promising approach that may revolutionize ocular drug delivery and open new possibilities for treating various ocular diseases while minimizing adverse effects on healthy eye tissues.

Determination Methods and Influencing Factors of Grain Mechanical Properties

Grain is extremely vulnerable to external loads during production and processing, resulting in the deterioration of grain quality. Deteriorated grain not only affects the economic value of grain but also affects the safety of storage. This has a very important relationship with the biomechanical properties of grains. It is of great significance to explore the mechanical properties of grain under different conditions and analyze the relationship between its physical and chemical properties and mechanical properties for improving its processing and eating quality. In this paper, the research methods of the mechanical properties of grains are reviewed. Various factors influencing the mechanical properties of cereals were analyzed. The relationship between the internal organizational structure of grain and its mechanical properties was discussed. This paper puts forward the shortcomings in the current research on the mechanical properties of grains and puts forward the prospect and analysis of its importance in future development in order to provide a reference for reducing crushing in the grain processing process.

Dams in the Mekong: a comprehensive database, spatiotemporal distribution, and hydropower potentials

Abstract. Dams have proliferated along the Mekong, spurred by energy demands from economic development and capital from private companies. Swift dam evolution has rendered many databases outdated, in which mismatches arise from differing compilation methods. Without a comprehensive database, up-to-date spatial assessment of dam growth is unavailable. Looking at future development, hydropower potential specifically within the Mekong remains to be systematically evaluated. In this paper, we offer (1) an open-access and unified database of 1055 dams, (2) a spatiotemporal analysis of dams on a sub-basin and country level from the 1980s to the post-2020s, and (3) a grid-based assessment of the theoretical basin-wide hydropower potential using present-day discharge from the CaMa-Flood model (2011–2015, 0.05°) and future discharge from the WaterGAP2 model used for ISIMIP2b (2021–2040, 0.5°). The dam count of 1055 is more than twice the largest existing database, with 608 hydropower dams generating a boom in hydropower capacity from 1242 MW in the 1980s to 69 199 MW post-2020s. While China had the largest capacity increase from the 2000s to the 2010s (+16 854 MW), Laos has the most planned dams and the highest projected growth post-2020s (+18 223 MW). Based on present-day discharge, we estimate a basin-wide hydropower potential of 1 334 683 MW, where Laos is the highest at 514 887 MW. Based on future discharge modeled with climate change, hydropower potential could grow to over 2 000 000 MW. Laos and China are the highest at around 900 000 MW each, together forming over 80 % of the total potential. Our database facilitates research on dam-induced hydrological and ecological alterations, while spatiotemporal analysis of hydropower capacity could illuminate the complex transboundary electricity trade. Through both spatiotemporal and hydropower potential evaluation, we address the current and future vulnerability of countries to dam construction, highlighting the need for better planning and management in the future hydropower hotspot Laos. The Mekong dam database is publicly available at https://doi.org/10.21979/N9/ACZIJN (Ang et al., 2023).

GIS-MCE based suitability analysis for sustainable estate development in Ede North LGA Osun State, Nigeria

Ideal areas for housing developments that are, for the most part, sustainable present critical issues in the planning and development of eco-friendly urban settlements. With this in mind and explicitly, Ede North LGA of Osun State was chosen as the case study, where a methodological framework for a land suitability analysis was adopted to identify suitable lands for real estate development with sustainability as a focus in the realization of global UN goals. This present study falls within the framework of the Multi-Criteria Evaluation (MCE) analysis, which can be integrated into Geographic Information Systems (GIS) together with the Analytic Hierarchical Process (AHP), useful for decision-making in site selection studies. For this purpose, computed relative weights from the pairwise comparisons (AHP) of 5 sub-models, i.e., terrain, environmental, socio-economic, available land, and soil factors, were inserted into the suitability analysis function of GIS and combined in a ‘Weighted Sum’ overlay operation to produce a final suitability map on a scale of 1–5, with 5 being the highest preference. Lastly, the ‘Locate Region’ Spatial Analyst tool was applied to the final suitability map to locate three (3) optimum locations to site the estate developments. Conclusively, in view of the analysis and discoveries made in this research, finding optimum locations via the GIS-MCE-based land suitability model for future housing development needs may prove highly resourceful. Hence, this study can likewise give a significant direction to future land use changes and practical and cost-effective arrangements in urban areas where conditions are similar to those in Ede North LGA.

Leadership development in the Hong Kong Civil Service: Accessing social resources through guanxi networks

AbstractDrawing on guanxi and conservation of resources theory we explore how close personal ties between middle managers who participated in leadership development, constitutes an important social resource in an East Asian public sector context. We contribute to studies exploring the importance of informal leadership development opportunities and techniques, specifically utilised to overcome public sector structural barriers. We gathered qualitative data from 44 middle managers who had completed formal leadership development within the Hong Kong Civil Service. Our data revealed that high quality Superior‐to‐Subordinate Guanxi helped study participants to gain access to important development resources including further developmental opportunities, stretch assignments, developmental support and feedback. High quality Peer‐to‐Peer Guanxi helped them to gain access to peer tacit knowledge, participation in collaborative development projects and positive peer developmental feedback. Our findings inform future leadership development design and are relevant to East Asian public sector context's where guanxi ties are significant.

Special Educators’ Training and Preparedness to Write Individualized Education Programs

Over the last decade, there has been ample evidence reporting the lack of high-quality and compliant Individualized Education Programs (IEPs) in the United States. This problem has many consequences, including poor student outcomes and failure to follow legal due process. Despite these consequences, research has not thoroughly examined the perspectives and needs of special educators on IEP development or the role of pre-service training on special educators’ ability to write high-quality, compliant IEPs. To address this gap, this study surveys 218 Pennsylvania special educators to examine their perspectives on the sufficiency of their pre-service training to write high-quality IEPs. Data on the types of training and support special educators need to successfully write IEPs were also gathered. Results provide information on needed teacher preparation program components, supports for in-service special educators when writing IEPs, and areas for future professional development. Implications and future directions for training on writing IEPs are discussed.

Mental health clients’ receptiveness to and recommendations for integrating physical activity discussions into therapy: a mixed methods study

Objective The mental health benefits of physical activity are well-established. Integrating physical activity counseling into therapy would expand the reach of this evidence-based treatment for mental illness. This mixed methods study examined mental health clients’ receptiveness and recommendations for effectively discussing physical activity in therapy. Methods A diverse sample of U.S. adults in therapy (N = 478) completed a survey that included the open-ended question: What specific recommendations would you have for your therapist to effectively discuss physical activity with you? We conducted a qualitative content analysis to identify their most common recommendations. Results Most participants indicated they would be comfortable discussing physical activity with their therapist. The content analysis resulted in 26 unique categories; most common recommendations included: provide information about what to do (n = 81), discuss physical activity benefits (n = 63), be understanding and nonjudgmental (n = 49), provide accountability (n = 41), and consider physical/mental health conditions (n = 35). Overarching themes emphasized making mental health central to discussions, tailoring discussions to each client, and reframing physical activity as a feasible, enjoyable activity. Conclusions Mental health clients are open to discussing physical activity during therapy if it is approached in a supportive, understanding, and personalized way. Clients’ recommendations can inform future professional development for therapists.

Using Corpus Linguistics in Materials Development and Teacher Education

In published ELT materials, norms relating to written language often dominate, at the expense of spoken language. This dominance of writing typically arises as the features characteristic of everyday spoken language do not reflect the rather neat syllabi expected by teachers and students, globally. Furthermore, there are deeply held opinions relating to the usage and acceptability of features of spoken language. As a result, features of spoken language are often not represented in mainstream materials, despite a perennial request from learners for more ‘conversation’. One potential means to meet such a request is by employing corpus linguistics and spoken language research to inform ELT materials development and teacher education. Responding to this issue, this paper draws on findings from a corpus-based conversation analysis of spontaneous spoken British English to conduct workshops on materials development. The goal of these workshops is to gain a comprehensive perspective on the affordances of corpus linguistics for ELT materials development from core stakeholders: teachers. Through a grounded theory-based thematic analysis of lesson plans, recorded discussions, and survey responses, the findings of this study demonstrate that teachers find value in corpus linguistics research. Specifically, the teachers’ insights offer recourse for developing strategies for exploiting corpora better in future ELT materials development. Moreover, teachers signalled effective means through which corpus linguistics can be embedded in future teacher education.

Motivators and barriers to plant-based product consumption across Aotearoa New Zealand flexitarians

Limited knowledge exists concerning Aotearoa New Zealand (A-NZ) flexitarians and their respective motivators and barriers towards consumption of novel plant-based products (PBPs) heralded as aids for dietary meat reduction. This study aimed to determine if A-NZ flexitarians, who have tried novel PBPs, can be segmented based on different motivators and barriers to meat reduction and PBP consumption, if the consumer profile of the different segments varies according to identified gender, generation group, neophobia and meat and PBP consumption frequency. It also aimed to identify sensory characteristics novel PBPs need to possess to be attractive to A-NZ flexitarians and if these vary across segments. PBP-consuming flexitarians (n = 584), stratified according to age (Millennial/Gen X), identified gender and meat consumption frequency, completed an online survey regarding a) their level of agreement regarding statements related to factors driving PBP consumption and flexitarianism in general, and b) their satisfaction with the sensory experience of consuming current PBPs. ‘Tastes good’ was the top-rated factor for selecting PBPs for all consumers, but most were dissatisfied with the sensory characteristics of current PBPs. K-means cluster analysis identified three flexitarian segments based on similarities and differences in key motivations and barriers to consume PBPs. Attitudes and behaviours related to nutrition/health, and social status attained from eating both PBPs and meat products, accounted for most variation across the respondents. Overall, higher food neophobia was associated with higher PBP consumption, suggesting that neophobia itself is not necessarily a barrier to PBP consumption in A-NZ flexitarians. Improving the sensory profiles of PBPs whilst delivering nutritional requirements presented as key considerations for future product development and research. This research highlights the importance of understanding the distinct values, attitudes and behaviours of different flexitarian groups as opposed to generalised research aimed at flexitarians per se.

A Critical Inquiry into ‘Abuse’ in EU Competition Law

Abstract Disagreement abounds on what exactly constitutes an ‘abuse’ within article 102 TFEU, EU competition law’s prohibition of an abuse of a dominant position. This situation is highly undesirable, given the important role this prohibition is expected to play in alleviating concerns about substantial market power and its use in important sectors, typified by actions against ‘Big Tech’. This article responds to this problem by analysing and synthesising the jurisprudence of the Court of Justice of the European Union and its evolution to establish the constituent elements of an exclusionary ‘abuse’. The article corrects crucial legal misconceptions, including the putative dichotomy between violations ‘by object’ and ‘by effect’; the assumed disparate legal tests for pricing and non-pricing conduct; and the lost distinction between the ‘as efficient competitor test’ and the ‘as efficient competitor standard’. This critical inquiry allows one to draw concrete predictions on the future development of this challenging, yet vital, area of law.

Recent Progress of the Application of Electropolymerization in Batteries and Supercapacitors: Specific Design of Functions in Electrodes

AbstractElectrochemical energy storage devices play a vital role in human life, and the requirements for their sustainability and environmental friendliness have been increasing in recent years. Electropolymerization, as a convenient method for polymer synthesis, has attracted increasing attentions in applications in the field of energy storage and conversion. It is not only commonly employed for the fabrication of various self‐supporting electrodes, but also is one of the most promising preparation strategies for organic electrode materials, internal interlayers within electrodes, functional protective layers, and current collector surface modifications. Previously published works have confirmed that the introduction of electropolymerization can effectively improve the electrochemical performance of various energy storage devices. However, there are still challenges in the universality of the synthesis route, in‐depth understanding of interface chemical behavior, and scaled‐up production. This mini review summarizes the main components in electropolymerization, material synthesis mechanisms, and their application principles in batteries and supercapacitors. Additionally, the current challenges and future development directions of electropolymerization have been discussed, offering some perspectives for further exploration.

Nontoxic, Biodegradable Hyperbranched Poly(β-amino ester)s for Efficient siRNA Delivery and Gene Silencing.

RNA interference (RNAi)-mediated gene silencing is a promising therapeutic approach to treat various diseases, but safe and efficient delivery remains a major challenge to its clinical application. Non-viral gene vectors, such as poly(β-amino esters) (pBAEs), have emerged as a potential candidate due to their biodegradability, low toxicity profile, ease of synthesis, and high gene transfection efficiency for both DNA and siRNA delivery. However, achieving significant gene silencing using pBAEs often requires a large amount of polymer carrier (with polymer/siRNA weight ratio >100) or high siRNA dose (>100 nM), which might potentially exacerbate toxicity concerns during delivery. To overcome these barriers, we designed and optimized a series of hyperbranched pBAEs capable of efficiently condensing siRNA and achieving excellent silencing efficiency at a lower polymer/siRNA weight ratio (w/w) and siRNA dose. Through modulation of monomer combinations and branching density, we identified the top-performing hyperbranched pBAEs, named as h(A2B3)-1, which possess good siRNA condensation ability, low cytotoxicity, and high cellular uptake efficiency. Compared with Lipofectamine 2000, h(A2B3)-1 achieved lower cytotoxicity and higher siRNA silencing efficiency in HeLa cells at a polymer/siRNA weight ratio of 30 and 30 nM siRNA dose. Notably, h(A2B3)-1 enhanced the gene uptake in primary neural cells and effectively silenced the target gene in hard-to-transfect primary cortical neurons and oligodendrocyte progenitor cells, with gene knockdown efficiencies of 34.8 and 53.4% respectively. By incorporating a bioreducible disulfide compartment into the polymer backbone, the cytocompatibility of the h(A2B3)-1 was greatly enhanced while maintaining their good transfection efficiency. Together, the low cytotoxicity and high siRNA transfection efficiency of hyperbranched h(A2B3)-1 in this study demonstrated their great potential as a non-viral gene vector for efficient siRNA delivery and RNAi-mediated gene silencing. This provides valuable insight into the future development of safe and efficient non-viral siRNA delivery systems as well as their translation into clinical applications.

Enhanced biomass and lipid production from olive processing wastewater using Scenedesmus obliquus in a two-stage cultivation strategy under salt stress

The study enhanced Scenedesmus obliquus cultivation via optimization of C/N and C/P ratios in synthetic media and evaluation of a two-stage cultivation strategy through application of salinity stress in olive processing wastewater-based feedstocks. S. obliquus under 40/1 C/N ratio performed biomass and lipid productivity that reached 0.15 and 34.1 mg L−1 d−1 respectively, demonstrating high glucose removal efficiency. Application of a two-stage cultivation strategy employing 0, 10, 20 and 30 g L−1 NaCl during the second bioprocess segment resulted in elevated biomass productivity (0.14–0.19 g L−1 d−1), which was reduced under batch mode yielding 0.11 g L−1 d−1. Two-stage cultivation triggered higher lipid productivity (4.2%-156.9%) following 3 d and 6 d upon the onset of the second stage (42.7–55.2 mg L−1 d−1) as compared to batch conditions, while the utilization of reducing sugars in exhausted olive pomace hydrolysates and table olive processing wastewater reached 53.6%-61.2%. Proline, glycerol and reactive oxygen species accumulated at considerable levels employing 20 and 30 g L−1 NaCl, indicating that S. obliquus expressed cellular stress under elevated salinity content, which was not notably stimulated using 10 g L−1 NaCl. The use of olive processing wastewater in a two-stage cultivation strategy under stress conditions enables future development of algal biorefinery systems for production of S. obliquus biomass and polyunsaturated fatty acids as high added-value products from biowaste.

Augmented Reality (AR) Solar System Objects Based on Marker Based 3D

This research implements Augmented Reality (AR) technology in solar system learning using a marker-based 3D object recognition method. The aim of this research is to create an interactive and immersive experience for users to learn about the solar system through an Android smartphone. The research development method follows the waterfall approach, which includes requirements analysis, system and software design, implementation, integration, testing, and maintenance. This AR application utilizes marker-based 3D object recognition technology on an Android smartphone. The test results demonstrate the success of the application in displaying 3D objects during the scanning process using marker cards. Distance testing indicates that the optimal range for recognizing solar system objects is 20-30 cm. Meanwhile, light intensity testing reveals that outdoor daylight conditions with an intensity of 90-120 Lux provide optimal results. In conclusion, this research successfully develops an application for recognizing solar system objects using AR technology. The application offers an interactive learning experience for the solar system. The utilization of the waterfall method and the positive test results are the strengths of this research. For future development, the consideration of employing the scrum method can accelerate the application development and testing processes.

Tailoring Sub‐Doppler Spectra of Thermal Atoms with a Dielectric Optical Metasurface Chip

AbstractCompact and robust structures to precisely control and acquire atomic spectra are increasingly important for the pursuit of widespread applications. Sub‐Doppler responses of thermal atoms are critical in constructing high‐precision devices and systems. In this study, a nanograting metasurface specifically is designed for atomic rubidium vapor and integrated it into a miniature vapor cell. Using the metasurface with built‐in multifunctional controls for light, pump‐probe atomic spectroscopy is established and sub‐Doppler responses are experimentally observed at low incident power. Moreover, the sub‐Doppler lineshape can be tailored by varying the incident polarization state. The spectrum transformation from absorption to transparency is observed. Using one of the sharp responses, laser stabilization with a stability of at 2 s can be achieved. This work reveals the effective control of atomic spectra with optical metasurface chips, which may have great potential for future developments in fundamental optics and novel optical applications.