Wireless Communications Systems are at the centre of a new and passionate era for telecommunications characterised, in industrial terms, by the convergence of systems and technologies, a transition towards all-IP networks, and the development of technologies with a user-centric focus. On the other hand, in terms of Research and Development, researchers are already considering other, more futuristic, aspects beyond those just mentioned, and these days hot topics include things like the Internet of the Future, and all the Post-IP perspectives that come with it. In both grounds, that is the more industrial related one and the one nearer an academic perspective, there is still a long way to go, before many of the ideas being discussed today can see the light of day as a commercial product. In this context, the International Symposium on Wireless Communication Systems (ISWCS) has positioned itself as a dynamic forum for researchers and technologists to present and discuss original ideas and contributions in all fields related to mobile and wireless communication systems. ISWSC'06, the 3rd edition, held in Valencia, Spain, on September 2006, brought together leading and enthusiastic researchers and technologists, willing to identify and discuss the future technical challenges and business opportunities arising in the path towards the realisation of ambient wireless communication networks. Besides this, it was a good forum for Ph.D. students to present their work, and exchange their ideas. The idea of setting up a special issue of a journal with the very best papers of the conference was brought up by the excellent quality of some papers presented at the conference. The objective of a special issue of this kind is always to put together, beyond the conference proceedings, the best papers in an enhanced and revised version, enabling the journal to publish good papers with timely updated information in a very short time. This special issue of Wireless Communications and Mobile Computing contains the very best papers presented at ISWCS'06. An invitation was sent to a restricted number of papers, and an additional review procedure was held, beyond the conference one. At the end, this set of six papers was accepted. The papers in this issue address some of the hot topics being investigated these days, ranging from localisation and frequency sharing to multi carrier-code division multiple access (MC-CDMA) and multiple input multiple output (MIMO). This shows that the physical layer still attracts a lot of attention, and that it still has a lot of topics to be explored. The first two papers address MIMO channels, in modelling or measurement perspectives. Matthias Pätzold and Bjørn Olav Hogstad present a model for a wideband MIMO channel based on the geometric elliptical scattering one, which can be used as a starting point for the derivation of a frequency-selective space–time channel simulator, being also useful for studying MIMO channel capacity under various propagation conditions. Michail Matthaiou et al. bring a paper on dual frequency MIMO measurements around the ISM 2.4 GHz band, in indoor environments, with initial results being promising enough, as the joint spectra seem to be remarkably similar, implying that the underlying propagation mechanisms at the considered bands are also similar. Farrukh Rashid and Athanassios Manikas present one of the papers dealing with MC-CDMA, namely on arrayed reception in space-time diffused multipath vector channels; results show that the use of a diffused channel modelling in arrayed receivers yields better bit error rate (BER) and signal to noise plus interference ratio (SNIR) performance than receivers that ignore the presence of spatial and/or temporal diffusion. The other paper on MC-CDMA, from Nguyen Tran Khoa et al., addresses frequency sharing in hotspot communications for cellular networks; it proposes an overlap in the uplink of an OFDM hotspot system to an MC-CDMA cellular one, in the same frequency band, beam-forming being applied to eliminate inter-system interference. The paper for Barbara Mavì Masini et al. also deals with the coexistence of different systems, in particular on the benefits of diversity schemes for Bluetooth coverage extension in the presence of IEEE 802.11g interference, analysing packet error and coverage probabilities, among other parameters. Finally, Joseph Shmuel Picard and Anthony Joseph Weiss present a paper addressing localisation of networks using various ranging bias models, presenting a set of iterative algorithms that cope successfully with the various bias models and provide Maximum Likelihood position estimates.