Background: To assess the effectiveness of clinic-based vision therapy in adults with non-strabismic binocular vision anomalies. Methods: This retrospective study was conducted between January 2018 and December 2021 at a tertiary eye care center in Southern India. Elec-tronic medical records of adults aged 30 years and above diagnosed with non-strabismic binocular vision anomalies, and who underwent a mini-mum of five sessions of clinic-based vision therapy (VT), were reviewed. Clinical parameters of vergence and accommodation were analyzed pre and post-therapy. Results: A total of 44 participants meeting the inclusion criteria were included in the study, with a mean (SD) age of 36 (±6) years. The partic-ipants were categorized into two groups based on the completion of either five sessions (Group A) or ten sessions (Group B) of vision therapy (VT). The overall median (IQR) for near phoria was -4 (-8 to 0) PD, the near point of convergence break point was 8 (4 to 12) cm, fusional conver-gence amplitude for near was 25 (14 to 30) PD, and binocular accommo-dative facility and amplitude were 3 (0 to 6) cpm and 9 (7 to 10) D, respectively. Conclusion: Clinic-based vision therapy is efficacious in managing non-strabismic binocular vision anomalies in adult.