Gain Factor Research Articles

THE EFFECTIVENESS OF THE THINK TALK WRITE (TTW) LEARNING MODEL ON STUDENTS’ SCIENTIFIC COMMUNICATION SKILLS ON ECOSYSTEMS

Learning model plays a crucial role in improving students' communication skills. This research aims to determine the level of effectiveness of the Think Talk Write learning model on students' scientific communication skills on ecosystem material in class X MAS Al-Wardah. This type of research is descriptive research using a one group pretest-posttest design. The data collected in this research is attitude data on scientific communication skills and written scientific communication skills which are constructed based on six indicators of scientific communication skills. Attitude data on scientific communication skills were collected using the observation method and data on students' written scientific communication skills were collected using the test method. The research results showed that students' scientific communication skills attitudes increased with a gain factor of 0.31 in the medium category and also students' scientific communication skills in writing with an average gain of 0.4 in the medium category. Based on these results, it can be concluded that the Think Talk Write learning model is still less effective in improving students' scientific communication skills.

Exploring the modulatory effects of sotagliflozin on dyslipidemia in mice: The role of glucagon, fibroblast growth factor 21 and glucagon-like peptide 1.

Sotagliflozin is the first dual SGLT1/2 inhibitor antidiabetic drug approved by the US Food and Drug Administration for the management of heart failure. SGLT1/2 inhibition is observed to potentiate the secretion of the incretin hormone, glucagon-like peptide-1 (GLP-1). The current preclinical research sought to investigate the effect of sotagliflozin on the secretion of fat-regulating peptides such as GLP-1, glucagon and fibroblast growth factor 21 (FGF21) and their prospective association with sotagliflozin's potential beneficial effects on dyslipidaemia. During an oral fat tolerance test in mice, sotagliflozin substantially increased GLP-1 and insulin concentrations. Although sotagliflozin alone did not ameliorate postprandial lipemia, its combination with linagliptin (DPP-IV inhibitor) significantly improved lipid tolerance comparable to orlistat (lipase inhibitor). In a triton-induced hypertriglyceridemia model, sotagliflozin, along with other medications (fenofibrate, exenatide and linagliptin) reduced fat excursion; however, co-administration with linagliptin provided no extra advantage. Furthermore, sotagliflozin stimulated glucagon secretion in the alpha TC1.6 cells and healthy mice, which resulted in an increased circulating FGF21 and β-hydroxybutyrate concentration. Finally, chronic treatment of sotagliflozin in high-fat diet (HFD)-fed obese mice resulted in reduced body weight gain, liver triglyceride, cholesterol, interleukin-6 (IL-6) and tumour necrosis factor alpha (TNF-α) levels compared with the placebo group. However, the addition of linagliptin did not provide any additional benefit. In conclusion, sotagliflozin was found to have an effect on GLP-1 and also stimulate the release of glucagon and FGF21, which are important for regulating fat metabolism. Therefore, sotagliflozin might represent a potential therapeutic approach for the treatment of diabetic dyslipidemia and steatohepatitis.

Assessment of weight gain in adult patients living with HIV receiving first-line dolutegravir-based or efavirenz-based ART regimens in routine care clinics in Tshwane district, South Africa: An observational study.

Although dolutegravir (DTG) is deemed stable, safe, cost-effective, and clinically beneficial, it also carries the risk of side effects, including observed weight gain among patients on DTG-based antiretroviral therapy (ART) regimens. We compared weight changes among adults (≥18 years) initiating tenofovir disoproxil fumarate, lamivudine, and dolutegravir (TLD) or tenofovir disoproxil fumarate, emtricitabine, and efavirenz (TEE) regimens and those switching from TEE to TLD (TEE-to-TLD switchers) in three large primary care facilities in South Africa METHODS: We conducted a retrospective longitudinal record review using patient medical records, extracting relevant demographic and clinical data from October 2018 to June 2021 from randomly selected adults who initiated TLD or TEE (initiators) and adult TEE-to-TLD switchers. We assessed weight, body mass index (BMI), and percentage weight changes for both groups and fitted linear regression and generalized linear models to determine factors associated with weight and BMI change and percentage weight change ≥10%, respectively, among treatment initiators. We fitted linear mixed-effect models among TEE-to-TLD switchers to consider repeated measures. Of 860 initiators, 450 (52.3%) initiated on TEE and 410 (47.7%) on TLD, with median follow-up of 1.4 years and 1.0 year, respectively. At initiation, 43.3% on TEE and 40.8% on TLD were overweight or obese. TLD initiators had an adjusted higher mean weight gain of 1.6 kg (p < 0.001) and mean BMI gain of 0.51 kg/m2 (p < 0.001) than TEE initiators. Independent risk factors for higher mean weight and BMI included age ≥50 years, male, on ART for >12 months, initial BMI of <18.5 kg/m2, and CD4 counts <200 cells/μL. Of 298 TEE-to-TLD switchers, 36.6% were overweight or obese at TEE initiation. Comparing before and after TLD switch, TEE-to-TLD switchers had an adjusted mean weight of 1.2 kg less while on TLD (p = 0.026). Being overweight and CD4 counts >350 cells/μL were independent risk factors for lower weight gain after TLD switch. We report more weight gain among TLD than among TEE initiators, although to a lesser extent than previously reported. TEE-to-TLD switchers experienced less weight gain after TLD switch; return to health before receiving TLD may be a contributory factor. The current findings are reassuring for those switching to a DTG-based regimen.

Effect of valproic acid monotherapy on serum leptin and ghrelin levels in epileptic children (literature review)

The incidence of epilepsy varies between industrialized countries and developing ones. Anti-epileptic drugs are the standard of care for epilepsy management with sodium valproate being the most commonly prescribed anti-epileptic drug in children with epilepsy. Valproic acid (VPA) is a first generation anti-epileptic drug used widely as a monotherapy or part of polytherapy for a variety of seizures in children more than two years of age. It is stated that long-term treatment with VPA is associated with risks such as weight gain, hyperinsulinemia, metabolic syndrome, and cardiovascular disease. However,the exact pathogenesis of weight gain has not been clearly identified pathogenetically. Studying the effect of VPA monotherapy on possible causative factors (leptin and ghrelin levels) of weight gain would help in undertaking appropriate preventive actions alongside VPA therapy. We review the available literature on the research carried out on this subject in the following sections.

Cohort profile: Life-course experiences and pregnancy (LEAP)-A retrospective pregnancy cohort for life-course reproductive health research.

Life course factors may be associated with pre-pregnancy body mass index and gestational weight gain; however, collecting information on pre-pregnancy exposures and pregnancy health in the same cohort is challenging. The Life-course Experiences And Pregnancy (LEAP) study aims to identify adolescent and young adult risk factors for pre-pregnancy weight and gestational weight gain (GWG). We built upon an existing cohort study to overcome challenges inherent to studying life course determinants of pregnancy health. Participants in an ongoing prospective cohort study of weight-related health who identified as women. Retrospective cohort study. In 2019-2020, 1,252 women participating since adolescence in a cohort study of weight-related health were invited to complete an online reproductive history survey. Participants who reported a live birth were invited to release their prenatal, delivery, and postpartum medical records for validation of survey reports. Descriptive analyses were conducted to assess the characteristics of the overall cohort and the medical record validation subsample, and to describe adolescent and young adult characteristics of those with high (>80th percentile), moderate (20th-80th percentile), and low (<20th percentile) GWG z-score for gestational age and pre-pregnancy weight status. Nine hundred seventy-seven women (78%) completed the LEAP survey and 656 reported a live birth. Of these, 379 (58%) agreed to release medical records, and 250 records were abstracted (66% of the 379). Of the 977 survey respondents 769 (79%) reported attempting a pregnancy, and 656 (67%) reported at least one live birth. The validation subsample was similar to the overall cohort. Women with a high GWG had a higher adolescent BMI percentile and prevalence of unhealthy weight control behaviors than those with moderate or low GWG. LEAP offers a valuable resource for identifying life course factors that may influence the health of pregnant people and their offspring.

The Prevalence of Weight Gain After Obtaining Employment: A Cross-Sectional Survey of Employees at the Ministry of National Guard Health Affairs, Eastern Region, Saudi Arabia.

Background and objective Even though obesity is a major global health concern, few studies in the literature have discussed obesity in the workplace. In light of this, we aimed to explore obesity in the workplace and its contributing factors. Methodology An online survey was distributed via official work emails. The survey assessed demographic variables and work environment-related factors, such as physical and mental well-being, lack of time, and social and personal habits. The total sample included 380 full-time employees, of which 16.67% were excluded for not meeting the inclusion criteria. Data were analyzed by using descriptive and inferential statistics. Results Of note, 79.87% of the participants reported an increase in weight after getting employed. The average weight gain was 10.4 kg for 8.2 years of experience. The physical and mental items and time-related items had the highest average scores of 3.24 and 3.44, respectively. The multivariable logistic regression showed a significant association between work experience (p = 0.0259) and time (p = 0.0363), as well as physical and mental domains (p = 0.0007). Conclusions Based on our findings, greater work experience, a lack of time, and negative mental and physical well-being are risk factors for weight gain among employees.

Dispersion‐Engineered Super‐Gain Parametric Amplification in Nanoscale Optical Cavities

The gain factor of the optical parametric amplification (OPA) process is known to be negligible in the small scale due to low‐interaction‐medium length. Hence, in the nanoscale, OPA is deemed as infeasible. Therefore, in small‐scale‐integrated optical devices, stimulated‐emission‐based amplifiers (lasers) are employed instead of OPAs. In contrast, the major advantage of OPAs over lasers is that unlike lasers which only provide amplification over a narrow spectral band, OPAs provide high‐gain amplification over a very large, user‐controlled spectral band. In this article, it is shown that OPA can yield wideband high‐gain amplification over a nanoscale beam propagation distance through dispersion engineering. This is achieved by a proper tuning of the pump (source) wave frequency, which can maximize the effective medium nonlinearity by a few orders of magnitude, while concurrently maximizing the intracavity energy density, thereby compensating for the small co‐propagation distance for the input (signal) and pump beams. In this study, it is shown that an input wave can be amplified by a factor in a nanoscale cavity via precise dispersion engineering. Both empirical and computational formulations are used for the investigation, which display a reasonable agreement.

VIIRS Version 2 Deep Blue Aerosol Products

AbstractNASA's Deep Blue aerosol project has developed global aerosol data records using consistent retrieval algorithms applied to various satellite sensors. The primary components of these data records are derived from the series of Visible Infrared Imaging Radiometer Suite (VIIRS) aboard the Suomi National Polar‐orbiting Partnership (SNPP) and the National Oceanic and Atmospheric Administration or NOAA‐20+ satellites as well as the Moderate Resolution Imaging Spectroradiometer (MODIS), among others. These instruments provide over 23 years of measurements with similar radiometric characteristics for aerosol retrievals. The algorithms used for the initial Version 1 SNPP VIIRS data set were based on the MODIS Collection 6.1 Deep Blue algorithm over land and Satellite Ocean Aerosol Retrieval (SOAR) algorithm over water. For VIIRS Version 2 data reprocessing, major updates have been made to the algorithm suite, including better accounting for effects of surface pressure, improved determination of surface reflectance, and the inclusion of fine‐mode aerosol optical models to better represent anthropogenic aerosols over land. Cross‐calibration gain factors are derived for the NOAA‐20 VIIRS measurements to be consistent with the SNPP VIIRS, which allows the use of a unified algorithm package for both instruments. Comparisons against AERONET observations indicate that the Version 2 AOD data from SNPP VIIRS are significantly better than the Version 1 counterpart over land and slightly degraded over water in exchange for better spatial coverage. The AOD data from SNPP and NOAA‐20 VIIRS are comparable, indicating that cross‐calibration enables the creation of consistent aerosol data records using the series of VIIRS sensors.

Blue mussel (Mytilus edulis) silage, a possible low trophic marine protein source for Atlantic salmon (Salmo salar L.)

Blue mussel (Mytilus edulis) could be a promising marine protein source in fish feeds and is of great interest since it can be cultivated along the Norwegian coastline. However, the use of blue mussels in feeds is dependent on developing suitable preservation and processing methods to produce a feed grade raw material. The present studies were conducted to investigate whether blue mussel silage could be used in the feed for Atlantic salmon post-smolt. Two feeding experiments were conducted using the same reference diet with FM inclusion of 25%, giving a mix of ∼59–63% plant-based ingredients vs ∼34–36% marine ingredients to simulate a standard grower feed for salmon post-smolts in SW. In experiment 1, fish were fed diets containing three different inclusion levels of blue mussel silage (BMS 3, 7, and 11%), a diet containing blue mussel meal (BMM) (12%) as well as the reference feed. In this experiment, the fish that were fed a diet containing BMS had a decline in both weight gain and condition factor when compared to the fish given the reference and BMM. The daily feed intake was similar in all groups, but the feed conversion ratio (FCR) increased in the fish fed BMS. The inclusion of BMS and BMM did not affect the digestibility of nutrients, but reduced retention of whole-body lipid and protein retention was observed. Salmon given BMS in the diet also had lower iron (Fe) concentrations in liver and whole body, indicating lower Fe uptake, irrespective of inclusion level. These findings were followed up in a second feeding experiment aiming to investigate whether different processing methods of blue mussel silage could influence the bioavailability of iron, as well as feed utilization and growth. The reference feed was formulated similar to the feed in exp. 1. Additionally, fish were fed diets containing BMM (9%) and the same batch of BMS (9%) used in exp. 1 as well as two diets containing new productions of BMS (9%) using either a lower acid level or only formic acid at the same level. In experiment 2, no differences were seen in weight gain, feed intake, FCR, nutrient retention or body composition between fish given BMS and reference diet. The lower Fe status observed in experiment 1 was not seen in the second study. In both experiments, there were no differences in fish welfare indicators between the group of fish fed with BMS, BMM and the reference group.The present results show that blue mussel silage can be used in the diet for Atlantic salmon, however, the different processing and preservation methods to produce BMS influence the nutritional properties and consequently growth performance and feed utilization of Atlantic salmon post-smolts.

Prevalence and associated factors of obesity in patients with major depressive disorder at different ages of onset.

Major depressive disorder (MDD) and obesity are two serious public health problems. Although there have been some research on both, there have few studies on differences in obesity among MDD patients at different ages of onset. The study aims to evaluate the prevalence and factors associated with obesity in MDD patients at different ages of onset. This study totally recruited 1718 first-episode drug-naive MDD patients aged from 18 to 60years. All subjects were divided into two subgroups: early adulthood onset (EAO, 18-45years) and mid-adulthood onset (MAO, 45-60years). Clinical symptoms of patients were evaluated using the 17-item Hamilton Depression Rating Scale (HAMD-17), Hamilton Anxiety Scale (HAMA), and Positive and Negative Syndrome Scale (PANSS) positive subscale. Baseline parameters including body mass index (BMI), blood pressure, and hematological biochemical parameters were assessed to investigate the association between these parameters and weight gain risk. The percentages of overweight and obesity patients with MDD in EAO group were 54.4% and 4.1%, respectively, and the percentages of overweight and obesity patients with MDD in MAO group were 60.4% and 2.8%, respectively. MDD patients in the MAO group had a longer duration of illness and higher scores in HAMD, HAMA, and PANSS positive subscale. They also had higher levels of thyroid stimulating hormone (TSH), anti-thyroglobulin (TgAb), fasting blood glucose (FBG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), systolic and diastolic blood pressures (SBP and DBP) levels. BMI did not differ significantly between the two groups. In the EAO group, statistically significant differences were found among normal weight, overweight and obese group in duration of illness, age of onset, TSH, TgAb, thyroid peroxidase antibody (TPOAb), free thyroxine (FT4), TC, triglycerides (TG), SBP and DBP. The TSH, TgTb and SBP were identified as risk factors for weight gain. In the MAO group, statistically significant differences were found among normal weight, overweight and obese group in TSH and FBG. The two indicators were identified as risk factors for weight gain. There were no significant differences in the weight of MDD patients at different ages of onset, while the factors that could potentially lead to obesity did show some differences.

Rigorous Analysis and Design of Resistor-Loaded Patch Antennas with Flexible Gain for Indoor Radar Sensors

A high-precision cavity model of resistor-loaded patch antenna (RLPA) with adjustable gain is proposed and rigorously studied in this article. In our analysis, the loaded resistors are perceived as controlled current sources, thus the RLPA can be solved as a modified cavity model. Accurate expressions of field distribution, input impedance, and radiation patterns are derived in this way, and a gratifying agreement has been achieved between the calculated and simulated results. Based on this approach, RLPAs for indoor motion radar are designed and analyzed. Comprehensive analysis is conducted to reveal the loading effect on radiation gain, radiation efficiency, and quality factor of RLPAs under various circumstances. Through altering the value of the loaded resistance, its radiation gain and coverage range can be flexibly adjusted. Besides, enhanced operating bandwidth and improved performance stability are also achieved due to the loaded resistors. Last but not least, several indoor motion radars based on the proposed patches are carried out and measured, which demonstrates the validity of the proposed method and design.

Weight, weight gain and behavioural risk factors in women attending a breast cancer family history, risk and prevention clinic: an observational study

BackgroundWeight and health behaviours impact on breast cancer risk. We describe trends in weight and health behaviours in women at entry to a specialist breast cancer family history clinic in Manchester, UK, and changes after clinic entry.MethodsQuestionnaires were completed at clinic entry (1987–2019, n = 10,920), and updated in 2010–11 (n = 3283). Clinic entry characteristics were compared between joining periods 1989–98, 1999–2008 and 2009–18. Partial Least Squares analysis characterised trends in weight, smoking and alcohol intake by age at entry, year of entry and birth year. Weight changes were compared over time, between joining periods.ResultsObesity at clinic entry increased from 10.6% in 1989–98 to 20.5% in 2009–18. Alcohol intake above recommendations and smoking prevalence decreased from 20.1% to 13.8% and 33.5% to 16.1% respectively. Weight gain was median 9.7 (IQR 1.4–20.6) % between age 20 and clinic entry (mean duration 11.9 ± 5.6 years) and a further 4.5 (0.0–12.5) % between clinic entry and 2010–11 (31.1 ± 10.4 years). Weight gain between age 20 and clinic entry was highest in the most recent joining period.ConclusionsObesity and weight gain are common in women attending a breast cancer family history clinic suggesting a need for weight management advice and support.

The entanglement and nonclassical properties of multi-photon amplified added based two-mode entangled coherent states

We explore into the non-classical characteristics of a new entangled coherent state (CS), also known as a multi-photon addition amplified coherent state (MPAACS) gn̂â†m, which is produced by adding any quantity of photons to two-mode coherent states with various gain factor values. A superposition of photon-added amplified two-mode CSs (MPAACS) also exists in this novel entangled state. It is proven that the gain factor and Laguerre polynomials are related to the MPAACS normalization factor. Analytical discussion is also had regarding entanglement and quantum statistical properties. Regarding concurrence, our findings further suggest that by selecting suitable values for the gain factor g, photon added (m,n), and coherent amplitude, entanglement for the output state can occur. Specifically, the enhancement of the entanglement can be found at large g values at fixed (m,n) in comparison to (m,n) values at fixed g and small amplitude with ϕ=0 or pi. Besides that, the analyses of nonclassicality reveal that, when comparing the results for several values (m,n) at fixed g and with several values g at fixed (m,n), the low-order antibunching effect, the cross-correlation function, and the Wigner function all support the sub-Poissonian statistics. When analyses of the nonclassicality and the negative value of the WF for ϕ=0 are larger at fixed parameter (m,n), but larger at g fixed for ϕ=π, the TMAA-TMC states perform better.

Density affects rearing performance of juvenile landlocked fall Chinook Salmon

AbstractObjectiveDensity‐related information for landlocked fall Chinook Salmon Oncorhynchus tshawytscha shortly after first feeding is poorly understood. This study was undertaken to determine the effects of a range of rearing densities (low, intermediate, and high) on rearing performance and survival of newly feed‐trained juvenile landlocked fall Chinook Salmon.MethodsThe fish were reared for 66 days in 1.8‐m (diameter) tanks with approximate volume of 2036 L at one of three loadings of approximately 2500, 5000, or 10,000 fish/tank.ResultThe initial and final densities for each of the three loadings were 0.73 and 8.93, 1.45 and 16.41, and 2.90 and 26.86 kg/m3, respectively. At the end of the study, the specific growth rates were significantly lower, total lengths were significantly shorter, and feed conversion ratios were significantly greater in the fish from the highest‐density treatment relative to the fish in the other treatments. Percentage of weight gain, final weights, and condition factor were significantly reduced in fish from the highest‐density treatment relative those at the lowest density. There were no significant differences in any growth metrics between fish that were reared at the lowest and intermediate densities. The intermediate density (5000 fish/tank) produced intermediate results that did not significantly differ from either the highest or lowest densities. Mortality was not significantly different among the density treatments.ConclusionAn initial loading of 5000 fish in 1.8‐m (diameter) circular tanks, corresponding to initial and final densities of 1.45 and 16.41 kg/m3, respectively, is recommended to minimize the detrimental effects of density on newly feeding Chinook Salmon while maximizing their production in often limited hatchery space.

Recent Insights and Recommendations for Preventing Excessive Gestational Weight Gain.

Recommendations for weight gain during pregnancy are based on pre-pregnancy body mass index (BMI). Pregnancy is a risk factor for excessive weight gain and many endocrine problems, making it difficult to return to pre-pregnancy weight and increasing the risk of postpartum obesity and, consequently, type 2 diabetes and metabolic syndrome. Both excessive gestational weight gain (EGWG) and obesity are associated with an increased risk of gestational hypertension, pre-eclampsia, gestational diabetes, cesarean section, shoulder dystocia, and neonatal macrosomia. In the long term, EGWG is associated with increased morbidity and mortality, particularly from diabetes, cardiovascular disorders, and some cancers. This study aims to present recommendations from various societies regarding weight gain during pregnancy, dietary guidance, and physical activity. In addition, we discuss the pathophysiology of this complication and the differential diagnosis in pregnant women with EGWG. According to our research, inadequate nutrition might contribute more significantly to the development of EGWG than insufficient physical activity levels in pregnant women. Telehealth systems seem to be a promising direction for future EGWG prevention by motivating women to exercise. Although the importance of adequate pre-pregnancy weight and weight gain during pregnancy is well known, an increasing number of women gain excessive weight during pregnancy.

THE DIFFERENCE CHANGE IN WEIGHT FAMILY PLANNING INJECTION ACCEPTORS THREE MONTHS WITH ONE MONTH IN MUARA VILLAGE CIREBON DISTRICT

Injected contraception is the most contraception method chosen by Indonesian women. There are 2 types of injected contraception, 3 monthly injecion which consists of progesterone only and 1 monthly injection consists of a combination of oesterogen-progesterone. One of its side effect is increase weight, which is usually distressing for women due to the increase risk of suffering from many diseases such as heart attack, type-2 diabetes mellitus, sleep apnea, certain cancer, osteoarthritis, and asthma. The study aim was to identify the difference weight gain occurence between 3 monthly and 1 monthly injected contraception users in Muara Village- Suranenggala District. This research method uses comparative analytic studies using cross sectional resulting research which measured in interval scale. The sample is all 3 months KB injecting participants as much as 30 respondents and 1 month KB injections as much as 30 respondents. The data is analysis using t-test. The result showed a ρ value of 0,005 which meant there was a difference in weight gain occurence between the users of 3 monthly and 1 monthly injected contraception. The 3 monthly injection had been proven increasing the incidence of weight gain compared to the 1 monthly one. It was suggested that midwives should give proper counselling regarding to side effect of increasing weight gain during the use of 3 monthly contraceptive injection to be aware of by the users. Further investigation on other influencing factors of weight gain among contraceptive injection users.

Ka-band phased array antenna with waveguide power distributor

Known designs of Ka-band phased array antennas incorporate an optical feed or a radial waveguide feed. Significant disadvantage of an optical feed is microwave energy overflow through antenna aperture, which decreases aperture efficiency and increases a side lobe level. Optical feed requires additional space for feeding antenna location and increases overall antenna dimensions. The design of a phased array with a radial waveguide feed forces placement of the phase shifter control circuits outside the dimensions of the array and increases overall antenna dimensions. The purpose of the article is to design a Ka-band phased antenna array (PAA) with a waveguide feed with smallest overall dimensions and various aperture shapes. The manufactured prototype of PAA with a grid pitch of 6x6 mm and size of 300x40 mm showed acceptable results of the side lobe level, scanning sector ±45° and gain factor. Proposed Ka-band phased array antenna design allows one to construct the extremely compact radar of various types including airborne radars.

EFFECT OF STOCKING DENSITY ON PRODUCTIVE PERFORMANCE OF JUVENILE OF THE BLACKSTRIPE CICHLID Vieja fenestrata (CICHLIFORMES: CICHLIDAE)

&lt;p class="18AbstractandKeywords"&gt;&lt;span class="Ninguno"&gt;&lt;strong&gt;&lt;span lang="EN-US"&gt;Background:&lt;/span&gt;&lt;/strong&gt;&lt;/span&gt;&lt;span class="Ninguno"&gt;&lt;span lang="EN-US"&gt; Native fish species are a developing alternative for sustainable aquaculture worldwide and in Mexico, the southern region is leading the efforts in freshwater species. &lt;strong&gt;Objective:&lt;/strong&gt; To assess the effect of different stocking densities on the productive performance of native fish juveniles of blackstripe cichlid (&lt;em&gt;Vieja fenestrata&lt;/em&gt;).&lt;em&gt; &lt;/em&gt;&lt;strong&gt;Methodology:&lt;/strong&gt; A one-factor randomized experimental design was used, evaluating in triplicate four stocking densities, 0.5 (L), 2 (M), 4 (H) and 6 (S) juvenile L&lt;sup&gt;-1&lt;/sup&gt;. The experiment lasted 30 days. Wet weight and total length were registered every 15 days and growth performance indices were obtained. &lt;strong&gt;Results:&lt;/strong&gt; Growth and survival were superior (P&amp;lt;0.05) for densities L and M. However, the M density showed a higher (P&amp;lt;0.05) growth rate, weight gain, and condition factor. &lt;strong&gt;Implications:&lt;/strong&gt; The stocking density showed an apparent effect on the growth and survival of juveniles of the blackstripe cichlid, with the M density showing the best results; however, a cost-benefit assessment is required before starting production of this tropical native species. &lt;strong&gt;Conclusion:&lt;/strong&gt; Our results suggest that a territorial and/or food competition was probably responsible for the survival and growth obtained. Although more studies are required, it appears that &lt;em&gt;Vieja fenestrata&lt;/em&gt; showed the typical patrons of behaviour of another most famous cichlids, as Nile tilapia, with high levels of aggression that depend on stoking density. &lt;/span&gt;&lt;/span&gt;&lt;/p&gt;

The role of lifestyle and mental health in the weight change of higher vocational college students in Fuzhou, China during COVID-19

ObjectivesThis study is aimed to explore the influence of higher vocational college students' lifestyle and mental health on weight change in Fuzhou during COVID-19. MethodsThis study adopted the cross-sectional study method and a total of 1426 students (1111 women and 315 men) were recruited from higher vocational college in Fuzhou. The questionnaire mainly included six dimensions: demographic characteristics, anthropometric measurements, dietary habits, physical activity, sleep quality and psychological status. ResultsAccording to the weight changes, the group was divided into weight loss group, constant weight group and weight gain group. More people in the weight gain group had increased their intake of various foods compared to the other groups (P < 0.001), in addition,the number of physical activity decreased and basically unchanged was more, and the number of sedentary time increased and basically unchanged was more in the three groups(P < 0.001). The incidence of poor sleep quality (60.3 %, 46.9 %, 57.5 %, P < 0.001), depressive symptoms (58.9 %, 47.5 %, 62.0 %, P < 0.001) and anxiety symptoms (42.5 %, 35.8 %, 45.3 %, P = 0.005) in the weight loss group and the weight gain group were significantly higher than those in the constant weight group. After adjusting for the potential confounders (including age, sex, grade, smoking, drinking, diet, etc.), decreased physical activity, depressive symptoms and anxiety symptoms were independent risk factors for weight gain compared with the constant weight group(OR = 1.643, P = 0.046; OR = 1.695, P < 0.001; OR = 1.389, P = 0.020). ConclusionsThe increased food intake, decreased physical activity, depressive symptoms and anxiety symptoms were positively correlated with weight gain.

Detection of sub-nmol amounts of the antiviral drug favipiravir in 19F MRI using photo-chemically induced dynamic nuclear polarization

In biological tissues, 19F magnetic resonance (MR) enables the non-invasive, background-free detection of 19F-containing biomarkers. However, the signal-to-noise ratio (SNR) is usually low because biomarkers are typically present at low concentrations. Measurements at low magnetic fields further reduce the SNR. In a proof-of-principal study we applied LED-based photo-chemically induced dynamic nuclear polarization (photo-CIDNP) to amplify the 19F signal at 0.6 T. For the first time, 19F MR imaging (MRI) and spectroscopy (MRS) of a fully biocompatible model system containing the antiviral drug favipiravir has been successfully performed. This fluorinated drug has been used to treat Ebola and COVID-19. Since the partially cyclic reaction scheme for photo-CIDNP allows for multiple data acquisitions, averaging further improved the SNR. The mean signal gain factor for 19F has been estimated to be in the order of 103. An in-plane resolution of 0.39 × 0.39 mm2 enabled the analysis of spatially varying degrees of hyperpolarization. The minimal detectable amount of favipiravir per voxel was estimated to about 500 pmol. The results show that 19F photo-CIDNP is a promising method for the non-invasive detection of suitable 19F-containing drugs and other compounds with very low levels of the substance.