Further Loss Of Life Research Articles

Hesitancy in COVID-19 Vaccine Uptake and Its Correlated Factors Using Multi-Theory Model among Adult Women: A Cross-Sectional Study in Three States of Somalia.

In developing countries, access to information, awareness, and availability of COVID-19 vaccines are key challenges. Somalia launched the COVID-19 vaccination in March 2021; however, the uptake of the vaccination is slow, which creates fear of further loss of life in the country unless intentional and organized campaigning and efforts are made to improve both the availability of the vaccine and its acceptance by the community. This study aimed to understand the current level of awareness, accessibility, trust, and hesitancy toward the COVID-19 vaccine among women in Somalia. To assess COVID-19 vaccine uptake, acceptance, community awareness, and hesitancy rates in Somalia, we carried out a cross-sectional mixed methods study in three regions of Somalia that were selected randomly out of the 18 regions of Somalia. A multi-theory model (MTM) was developed to identify correlated factors associated with the hesitancy or non-hesitancy toward COVID-19 vaccination among women of all ages (18 years and above). A total of 999 eligible women (333 in each district) of 18-98 years old were interviewed in March 2022. About two-thirds (63.76%) of participants reported hesitancy about receiving the COVID-19 vaccine. The theory model initiation construct indicated that behavioral confidence in the vaccine (b = 0.476, p < 0.001), participatory dialogue (at b = 0.136, p < 0.004), and changes in the physical environment (b = 0.248, p = 0.015) were significantly associated with COVID-19 vaccine acceptance among women who were not hesitant to take the vaccine. The availability of COVID-19 vaccines may not translate into their uptake. The decision to get the vaccine was determined by multiple factors, including the perceived value of the vaccination, previous experience with the vaccine, perceived risk of infection, accessibility and affordability, and trust in the vaccine itself. Public health education programming and messaging must be developed to encourage vaccine uptake among women with varying levels of vaccine hesitancy.

Oštećenja AB zgrada u İzmiru nakon potresa u Egejskom moru 30. listopada 2020.

An earthquake with a magnitude of Mw = 6.6 and a depth of approximately 16.5 km occurred on 30 October 2020 off the cost of Samos, a Greek island 35 km southwest of Seferihisar, a town in İzmir. The earthquake caused several collapses and severe structural damage in approximately 6,000 buildings, specifically in the Bayraklı District in İzmir Bay. This paper presents the observations and findings of a technical team that visited the earthquake-affected areas immediately after an earthquake. Eleven partially or fully collapsed buildings and several severely damaged reinforced concrete buildings were investigated. Based on the site observations, we observed that almost all of the collapsed or severely damaged reinforced concrete buildings in the region were built between 1975 and 2000. Site observations also confirmed that the construction of these collapsed or damaged buildings did not conform to the requirements outlined in the Turkish Earthquake Codes used at the time. The failures and severe damage to buildings in earthquake-affected areas are primarily related to inadequate reinforcement configuration, poor material quality, the absence of geotechnical studies, and framing problems related to their lateral load-carrying systems. Therefore, it is recommended that all the buildings located in and around İzmir Bay, particularly those built between 1975 and 2000, be structurally evaluated to prevent any further loss of life and property during future earthquakes.

A new Covid-19 diagnosis strategy using a modified KNN classifier

Covid-19 is a very dangerous disease as a result of the rapid and unprecedented spread of any previous disease. It is truly a crisis that threatens the world since its first appearance in December 2019 until our time. Due to the lack of a vaccine that has proved sufficiently effective so far, the rapid and more accurate diagnosis of this disease is extremely necessary to enable the medical staff to identify infected cases and isolate them from the rest to prevent further loss of life. In this paper, Covid-19 diagnostic strategy (CDS) as a new classification strategy that consists of two basic phases: Feature selection phase (FSP) and diagnosis phase (DP) has been introduced. During the first phase called FSP, the best set of features in laboratory test findings for Covid-19 patients will be selected using enhanced gray wolf optimization (EGWO). EGWO combines both types of selection techniques called wrapper and filter. Accordingly, EGWO includes two stages called filter stage (FS) and wrapper stage (WS). While FS uses many different filter methods, WS uses a wrapper method called binary gray wolf optimization (BGWO). The second phase called DP aims to give fast and more accurate diagnosis using a hybrid diagnosis methodology (HDM) based on the selected features from FSP. In fact, the HDM consists of two phases called weighting patient phase (WP2) and diagnostic patient phase (DP2). WP2 aims to calculate the belonging degree of each patient in the testing dataset to class category using naïve Bayes (NB) as a weight method. On the other hand, K-nearest neighbor (KNN) will be used in DP2 based on the weights of patients in the testing dataset as a new training dataset to give rapid and more accurate detection. The suggested CDS outperforms other strategies according to accuracy, precision, recall (or sensitivity) and F-measure calculations that are equal to 99%, 88%, 90% and 91%, respectively, as showed in experimental results.

Re: “Commentary” by Rothrock et al. “Meta-Analyses Did Not Establish Improved Mortality With Ivermectin Use in COVID-19”

Re: “Commentary” by Rothrock et al. “Meta-Analyses Did Not Establish Improved Mortality With Ivermectin Use in COVID-19”

COVID-19 Vaccines: Current Conditions and Future Prospects.

Simple SummaryThe coronavirus disease 2019 (COVID-19) pandemic, caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first encountered in December of 2019 in Wuhan, China. As of now, there have been over 200 million infections and 4 million deaths attributed to the virus. Due to this, it has been a priority to find an effective preventative measure, and numerous vaccines have been developed. Although the developed vaccines share the target of blocking viral entry by the spike protein, their pharmacology and efficacy differs. As such, the mechanism of action and the elicited immune response of the most common COVID-19 vaccines have been compared to help determine which vaccine is most efficacious and is best suited to prevent reinfection and address viral mutations.It has been over a year since SARS-CoV-2 was first reported in December of 2019 in Wuhan, China. To curb the spread of the virus, many therapies and cures have been tested and developed, most notably mRNA and DNA vaccines. Federal health agencies (CDC, FDA) have approved emergency usage of these S gene-based vaccines with the intention of minimizing any further loss of lives and infections. It is crucial to assess which vaccines are the most efficacious by examining their effects on the immune system, and by providing considerations for new technological vaccine strategies in the future. This paper provides an overview of the current SARS-CoV-2 vaccines with their mechanisms of action, current technologies utilized in manufacturing of the vaccines, and limitations in this new field with emerging data. Although the most popular COVID-19 vaccines have been proven effective, time will be the main factor in dictating which vaccine will be able to best address mutations and future infection.

The missing season: The impacts of the COVID-19 pandemic on influenza

Throughout the COVID-19 pandemic, many have worried that the additional burden of seasonal influenza would create a devastating scenario, resulting in overwhelmed healthcare capacities and further loss of life. However, many were pleasantly surprised: the 2020 Southern Hemisphere and 2020–2021 Northern Hemisphere influenza seasons were entirely suppressed. The potential causes and impacts of this drastic public health shift are highly uncertain, but provide lessons about future control of respiratory diseases, especially for the upcoming influenza season.

Haiti's Cholera Epidemic: When the Unexpected Must be Expected

Cholera has been around for centuries but in our modern history there has been a resurgence with at least 7 devastating global outbreaks occurring worldwide in in the last century each claiming thousands of innocent lives. Cholera infects 1.3 to 4 million people around the world, killing 21,000 to 143,000 people annually according to the World Health Organization (WHO). It is thus imperative to research this bacterial disease and come up with ways of shedding light on effective prevention and cure. Cholera is an illness of multi-causal origin where biological, environmental, social, political, and cultural factors intervene. This disease continues to resurge as a sanitary problem of great magnitude in many countries and emerged in Haiti following the January 12, 2010 magnitude 7.0 earthquake some 16 miles from the capital city of Port-au-Prince, where it caused massive damage to roads, buildings, and the environment. Although Haiti is among the poorest countries in the Americas, and its capital city lacked much in the way of modern public sanitation at the time of the earthquake, the country had been cholera free for at least 150 years or more at the time of the earthquake. By mid-October 2010, the first cases of cholera began to appear, and by the end of the decade would infect some 800,000 Haitians (~10% of the population of Haiti) and approximately 10,000 deaths. The source of the infection was traced to the Artibonite River, a main source of water in Haiti, which was believed to have become unknowingly contaminated by well-intentioned foreign workers from Nepal following the earthquake. The strain of cholera found in Haiti was similar to the one found in Nepal (CDC). Haiti employed measures of Cholera prevention and eradication efforts including water treatment, sanitation and hygiene measures, education, oral vaccination, and addressing climate variability issues, history, epidemiology, clinical diagnosis, and treatment, monitoring and prevention of this disease to prevent further loss of life. By 2020, no new cases of cholera have been reported for over 12 months, indicating that Haiti may soon be cholera free once again. Results/Conclusion: Effective hygienic conditions, timely medical intervention including supportive care, access to the appropriate antibiotics, availability of clean drinking water, hand washing, and other prevention protocols can help curb the loss of life associated with cholera. Cholera can kill a healthy person within 12 to 24 hours from the onset of diarrhea, as it is quite virulent. The current situation of cholera in the world (particularly in Haiti), and the extensive collaborative relation and the geographical proximity to Haiti makes the epidemiological risk in neighboring countries increase; therefore, immediate action is required in the organization of health services to prevent yet another epidemic.

Tourism Governance in the aftermath of COVID-19: A Case Study of Nepal

The global pandemic of COVID 19 has had a severe effect in various developing economies, including Nepal itself, as it has seriously engulfed the strongest economies of the world. The tourism industry globally has been paralyzed, and it will take long ahead to get the industry back on track. There are challenges to revive this industry and ensure its tremendous contribution to revitalizing the ailed tourism sector. To drive this situation more efficiently and tactfully, the need for good governance through its leading agencies seem to be much demanding and prevailing. Visit Nepal 2020 has been postponed by the Nepal government due to the potential risk of an outbreak of COVID -19 and almost all the government efforts have now been centralized to combat the threat of COVID-19. Both domestic and international tourism is in its complete halt, creating a massive shortfall on revenue generation in the national economy. To combat the spread of COVID-19 into the community level and thus checking the further loss of lives and property, series of lockdown at the national level were imposed restraining the public mobility, factories, and industries are closed for indefinitely leaving the tourism activities completely at coma. As the tourism industry globally has come to a halt now, stopping all the tourism-based activities resulting cut off of a heavy chunk of revenue, it’s a high time to think over the noble strategies on what might be the forms and modality of governance in tourism sector globally.

Optimize Edilmiş ÇKA ile Covıd-19 Sınıflandırması için Kaynaştırılmış Derin Özelliklere Dayalı Sınıflandırma Çerçevesi

The new type of Coronavirus disease called COVID-19 continues to spread quite rapidly. Although it shows some specific symptoms, this disease, which can show different symptoms in almost every individual, has caused hundreds of thousands of patients to die. Although healthcare professionals work hard to prevent further loss of life, the rate of disease spread is very high. For this reason, the help of computer aided diagnosis (CAD) and artificial intelligence (AI) algorithms is vital. In this study, a method based on optimization of convolutional neural network (CNN) architecture, which is the most effective image analysis method of today, is proposed to fulfill the mentioned COVID-19 detection needs. First, COVID-19 images are trained using ResNet-50 and VGG-16 architectures. Then, features in the last layer of these two architectures are combined with feature fusion. These new image features matrices obtained with feature fusion are classified for COVID detection. A multi-layer perceptron (MLP) structure optimized by the whale optimization algorithm is used for the classification process. The obtained results show that the performance of the proposed framework is almost 4.5% higher than VGG-16 performance and almost 3.5% higher than ResNet-50 performance.

The Interaction of Natural and Vaccine-Induced Immunity with Social Distancing Predicts the Evolution of the COVID-19 Pandemic.

The existence and nature of immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are currently unknown; however, neutralizing antibodies are thought to play the major role and data from studying other coronaviruses suggest that partial clinical immunity lasting up to 1 year will occur postinfection. We show how immunity, depending on its durability, may work with current social practices to limit the spread of the virus. We further show that a vaccine that is 50% effective and taken by 50% of the population will prevent further loss of life, providing that social distancing is still practiced and that immunity does not wane quickly.IMPORTANCE The ability of our society to function effectively moving forward will depend on how the spread of the SARS-CoV-2 virus is contained. Immunity to the virus will be critical to this equation.

Lack of access to CDK4/6 inhibitors for premenopausal patients with metastatic breast cancer in Brazil: estimation of the number of premature deaths.

PurposeA CDK4/6 inhibitor (CDK4/6i) combined with endocrine therapy is the standard of care for patients with hormone receptor-positive (HR+) and HER2-negative (HER2-) metastatic breast cancer (MBC). However, the incorporation of these agents into clinical practice remains challenging. This study aims to estimate the impact of the lack of access to ribociclib on mortality of premenopausal patients with MBC in Brazil.MethodsBased on published epidemiological studies and national cancer registries, we estimated the number of premenopausal patients with potential indication of ribociclib as first-line treatment for MBC. Efficacy estimates were based on results from the Monaleesa-7 trial. Our analysis is made under the unrealistic assumption that all premenopausal MBC patients would be candidates for the treatment. To estimate the number of yearly premature deaths that could be prevented, we considered the largest absolute effect on mortality when sequentially applying the observed hazard ratio.ResultsWe estimated an annual incidence of 4,294 premenopausal HR+, HER2- MBC patients in Brazil. Considering these patients, at 12, 24 and 60 months, the number of surviving subjects would be 3,504, 2,859 and 1,553 for endocrine therapy (ET) alone; and 3,717, 3,217 and 2,086 for ET plus ribociclib. The largest difference between both groups was observed at the end of the sixth year when the use of ribociclib would prevent 538 premature deaths (survival of 1,805 versus 1,267 patients by the 72nd month).ConclusionWe estimate that lack of access to CDK4/6i for patients with HR+, HER2-, MBC will cause the premature death of a significant number of premenopausal women with MBC. The unavailability of effective therapies has measurable consequences. Progress in this area demands a concerted effort to prevent further loss of lives.

How much damage do serial homicide offenders wrought while the innocent rot in prison? A tabulation of preventable deaths as outcomes of sentinel events

ABSTRACT The criminal justice system has allowed serial homicide offenders (SHOs) to commit additional homicides by failing to identify them after their initial homicide. Recidivism has been possible in instances where the SHO benefited from the wrongful incarceration of an innocent person for one of their homicides. Data from the National Registry of Exonerations was utilized to tabulate the full extent of these sentinel events, defined as the number of deaths that could have been prevented. Additional research was conducted to identify where victims fell in the offender’s killing sequence. This ancillary data revealed the number of victims whose deaths could have been prevented had the offender been apprehended earlier in their series of homicides. Sixty-two SHOs were responsible for 249 deaths, 114 of which were committed after an innocent person was incarcerated for the SHO’s initial homicide. To prevent further loss of life, law enforcement must: act upon accurate information; lower the SHO evidentiary threshold; prevent personal bias from influencing investigative steps; obtain training in the behavior of SHOs; admit mistakes; and re-examine convictions if wrongdoing is suspected.

Nursing in the COVID‐19 pandemic and beyond: protecting, saving, supporting and honouring nurses

As the world tackles the largest public health event in more than a century, the COVID‐19 pandemic, the true value of nursing is being seen by politicians and the public. But while nurses are being praised for the vital work they do, many are being put into high‐risk situations, and some have died, because of a shortage of appropriate, high‐quality personal protective equipment. The International Council of Nurses has called for governments to make the provision of such equipment their number one priority to prevent further loss of life among the nurses caring for the world’s most vulnerable patients.

A wake-up call: COVID-19 and its impact on children's health and wellbeing

A wake-up call: COVID-19 and its impact on children's health and wellbeing

Characterization of structural failures founded on soils in Panyam and some parts of Mangu, Central Nigeria

Structural failure of buildings, roads, and other infrastructures has led to the loss of lives and monumental damage to the economy. In developing countries such as Nigeria, the failures are always attributed to the nature/type of soils in the area without considering other factors. With the increase in civil engineering constructions and the scramble for a limited portion of competent soils for such constructions, land, therefore, is becoming man’s most priced commodity for agriculture, residential and industrial purposes. No works of such have been done in the area, it is, therefore, imperative to study the cause(s) to prevent further loss of lives and the negative effects of such on the economy. The study was carried out at Panyam and some surrounding localities on latitudes N9021′ and N9026′ and longitudes 9011′E and 9016′E an area of 72 km2. A total of forty samples were collected out of which twenty were selected for swelling potentials determination due to their cohesive nature within the 1.5 m depth. To characterize the swelling of the soils, inferential testing methods; direct method comprising Liquid Limit and Plasticity Index with values ranging from 30% – 70% and 10% – 27% respectively, and the indirect method (Free Swell Index, FSI) whose values range from 9.1% – 90% were used. Most of the soils analyzed based on the geotechnical standards were categorized relatively safe for civil infrastructure. Structural studies employed the direct measurements of surface structures to get the orientations of structures measured. Landsat image and Total Magnetic Intensity (TMI) map of the area was acquired from the Nigerian Geological Survey Agency (NGSA) for subsurface structural analysis. The RTP-TMI (reduce to pole) grid data of the area were processed to improve magnetic anomalies associated with edges of surface/near-surface geological structures using the MAGMAP two-dimensional fast fourier transform (2D-FFT) filters package in Oasis Montaj v7.2 software. Geophysical studies using aeromagnetic data at a near-surface depth of 40 m and fractures measured on the surface both revealed a major trend in the NNE – SSW. It was observed that structures constructed across the major trend suffered little to moderate damage while those constructed along the major fractures trend suffered severe damage. It was concluded that both soils and fractures played individual roles in the collapse of infrastructure in the area.

Health and dignity of Palestine refugees at stake: a need for international response to sustain crucial life services at UNRWA

The UN Sustainable Development Goals affirm equality and dignity as essential to the enjoyment of basic human rights, including the right to the highest attainable standard of physical and mental health, which promotes global solidarity among all people, including refugees. The UN Relief and Works Agency for Palestine Refugees in the Near East (UNRWA) has provided support to Palestine refugees in Jordan, Lebanon, Syria, the Gaza Strip, and the West Bank since the 1950s. Today, however, conflict and violence, occupation, high levels of poverty, and other social determinants of health jeopardize the wellbeing of Palestine refugees. Health concerns include non-communicable diseases, mental health conditions, and access to hospital care. Additionally, UNRWA is continuing to face a severe funding crisis. Using a historical and health policy perspective, this Health Policy examines UNRWA strategies that facilitate continuous provision of health-care services for Palestine refugees. Given the increasingly volatile environment faced by this population, a multifaceted international response is needed to enable UNRWA to deliver sustainable services to Palestine refugees and avert further loss of life, dignity, and hope, pending a just and lasting solution to their plight in accordance with applicable international law and UN General Assembly resolutions.

The Legacy of the Russell Tribunal

Reviews 183 c:\users\ken\documents\type3402\rj 3402 050 red.docx 2015-02-04 9:19 PM THE LEGACY OF THE RUSSELL TRIBUNAL Stefan Andersson stefankarlandersson@live.com Michael Uhl. Vietnam Awakening: My Journey from Combat to the Citizens’ Commission of Inquiry on U.S.War Crimes inVietnam. Jefferson, nc and London : McFarland, 2007. Pp. vii, 255. isbn: 978-0-7864-3074-1. us$28.45. n the introduction to The Vietnam War on Campus (2001), Marc Jason Gilbert writes: … though critics of the anti-war movement on campus remain loath to admit it, at the forefront of the allegedly elitist, ignorant, draft-evading, placard-carrying (and perhaps card-carrying) campus protesters were soldier-turned-scholar members of the Vietnam Veterans Against the War (vvaw). These students knew the war as intimately as did any Pentagon pundit. They were also aware that other veterans had concluded that the limits on American foreign policymaking imposed by the demonstrations of their compatriots at home were undermining the war in which they had fought. They were, however, not only willing, but often eager to lead their fellow students in what they saw as an effort to save their nation’s honor and to prevent the further loss of life in Southeast Asia. (P. xiii) Michael Uhl is an example of such a student. His book was written to satisfy, in part, the requirements of a doctoral program at the graduate school of the Union Institute. It consists of two major parts, the first covering Uhl’s background, growing up in a middle-class family on Long Island, and the f= 184 Reviews c:\users\ken\documents\type3402\rj 3402 050 red.docx 2015-02-04 9:19 PM circumstances that led him to join the Counterintelligence Corps in Vietnam, and a second in which he chronicles through contiguous episodes his postwar years as a “front line activist in the anti-Vietnam War veterans’ movement” (p. 2). In this review I will limit myself to Uhl’s experiences as a former gi and graduate student looking for ways to express his protests. This led him to Jeremy Rifkin, Tod Ensign1 and the Citizens’ Commission of Inquiry into United States War Crimes in Indochina (cci), which had been created by Bertrand Russell’s private secretary and head of the brpf in New York, Ralph Schoenman, in November 1969 in connection with the news about the My Lai Massacre, which had taken place in March in 1968. After the session of the iwct in Stockholm in May 1967, Schoenman went to Bolivia to be present at the trial of Régis Debray. When he tried to join the second session in Roskilde in November, American secret diplomacy was one step ahead of him. After several failed attempts to get into Denmark, he had to return to the us.2 This marked the beginning of the end of Schoenman’s relationship with the brpf, the iwct and Bertrand and Edith Russell. Back in the office on Fifth Avenue, he continued to handle the brpf correspondence . He succeeded in returning to the uk for a short time during the summer of 1968 and visited a surprised and concerned Russell in Wales, before he was deported. He returned to the New York brpf office. When the truth about the My Lai Massacre was revealed, Schoenman reacted immediately and started to organize the National Committee for a cci and look for former gis prepared to testify on war crimes, just as at the second session of the iwct in Roskilde.3 In “Organizing Veterans through War Crimes Documentation”, Ensign writes: While the Russell Tribunal hearings were known within the American peace movement, two more years passed before anyone began documenting u.s. war 1 Tod Ensign died in May 2014. I visited him at the Citizen Soldiers’ office in New York in June 2012 and had two long, exciting sittings with him when he told me stories about Schoenman, the cci, the failed cooperation with Jane Fonda, Mark Lane and the vvaw, Noam Chomsky, Richard Falk and much else, not all of it fit to print. He gave me a copy of G.I. Guinea Pigs (1980), which he...

Service use and unmet needs in youth suicide: a study of trajectories.

While 90% of suicide victims have suffered from mental health disorders, less than one-half are in contact with a mental health professional in the year preceding their death. Service use in the last year of life of young suicide victims and control subjects was studied in Quebec. We wanted to determine what kinds of health care services were needed and if they were actually received by suicide victims. We recruited 67 consecutive suicide victims and 56 matched living control subjects (aged 25 years and younger). We evaluated subjects' psychopathological profile and determined which services would have been indicated by conducting a needs assessment. We then compared this with what services were actually received. Suicide victims were more likely than living control subjects to have a psychiatric diagnosis. They were most in need of services to address substance use disorder, depression, interpersonal distress, and suicide-related problems. There were significant deficits in the domains of coordination and continuity of care, mental health promotion and training, and governance. Our results show that we need to urgently take action to address these identified deficits to prevent further loss of life in our young people.

Airdrop sites location problem and resources distribution for emergency relief

In emergency relief, airdropping and distributing of emergency resources to disaster-affected areas can effectively alleviate the sufferings of disaster victims and prevent further loss of lives and properties. In this study, an airdrop sites location and distribution model is developed to consider the distribution gaps between airdrop sites and demands sites when the distribution related resources are scare. The total cost of emergency relief and distribution is optimised, including airdrop cost, distribution cost, and transferring cost of the distribution devices. A simulation consisting of 16 alternative airdrop sites was analysed. The results showed that the model and algorithm are effective tools for scheduling airdrop and distribution in disaster relief. The study contributes to emergency management and disaster relief by linking the selection of airdrop and distribution sites. The model can be extended to the situation of multi-type emergency resources, multi-stage rescue, etc., to enhance the adaptability to real emergency logistics system.

The Lampedusa Disaster: How to Prevent Further Loss of Life at Sea?

Lampedusa – an Italian island barely 70 miles from northern Africa and 100 miles from Malta – has become a gateway to Europe for migrants. In some seasons, boats filled with asylum seekers arrive almost daily. However, yearly, hundreds of people die trying to cross the Mediterranean Sea. This paper will deal with the obligations of States towards seaborne migrants, the question of why so many people die near Lampedusa and the possible solutions in order to prevent further loss of life at sea.