To meet the needs of heat transfer and temperature uniformity in the heat dissipation of high-heat-flux electronic devices, a novel slit jet impingement heat sink with a protrusion in the stagnation region, droplet ribs in the wall jet region, and an inclined upper-plate (PDI-SJIHS) is proposed, the coolant is Al2O3-H2O nanofluid. The influences of the structural parameters of the above three components and the Reynolds number on the heat transfer and flow of the PDI-SJIHS are studied numerically. Using the comprehensive heat transfer and temperature standard deviation as objective functions, a multi-objective optimization of PDI-SJIHS is conducted using non-dominated sorting genetic algorithm-Ⅱ (NSGA-Ⅱ). The results indicate that the combination of the three components enhances the thermal performance of the PDI-SJIHS, compared with the slit jet impingement heat sink with only one of the above components. Rising the Reynolds number can enhance the thermal characteristics of the PDI-SJIHS. For a Reynolds number of 8000 and nanofluids with a 3% volume fraction, the average convective heat transfer coefficient, friction coefficient, and comprehensive heat transfer coefficient of the optimized PDI-SJIHS are increased by 182%, 153%, and 108%, respectively, and the standard deviation of temperature is 91% less than that of F-SJIHS.
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