Functionalized Core Shell Research Articles

Synthesis of phosphonic acid and amide functionalized core–shell magnetic composite and its mechanisms for synergistic adsorption of thorium from strongly acidic solution

To develop adsorbents for the preeminent extraction of thorium in strongly acidic solutions is very imperative, due to strong inorganic acids are frequently used in the fuel cycle of thorium. Herein, a robust core–shell magnetic nanocomposite Fe3O4@SiO2/P (MBA-VPA-AM) possessing phosphonic acid and amide was developed via distillation-precipitation copolymerization of N, N'-methylene diacrylamide (MBA), vinylphosphonic acid (VPA) with acrylamide (AM) employing Fe3O4 decorated by SiO2 (Fe3O4@SiO2) as magnetic core. Due to the synergistic effect of phosphonic acid and amide ligand, the sorbent could capture thorium from concentrated HNO3 media efficiently, and the maximum adsorption capacity (qmax) at 4 mol L−1 of HNO3 solution reached up to 232.5 mg g−1, superior to that of all magnetic sorbents reported previously. Furthermore, the sorbent displayed good selectivity towards thorium in the presence of competitive metal ions including La3+, Nd3+, and Ce3+. The excellent thorium sorption behavior in strong hydrogen nitrate solution was merely ascribed to the complexation of thorium with phosphonic acid ligand, and the amide ligand could not complex with thorium, evidenced by XPS, FT-IR and DFT method. However, the presence of amide ligand could enhance the hydrophilicity of the sorbent and the free movement degree of phosphonic acid ligand to a certain extent, both of which could help to promote the thorium sorption on the sorbent in strong HNO3 media. Besides, due to its core–shell structure and superparamagnetism, the sorbent not only exhibited excellent acidic resistance in strong acid medias, but could be magnetically recouped, which could avoid tedious centrifugation or filtration of traditional adsorbents. This work provides a novel strategy to develop magnetic sorbent for the preeminent entrapment of thorium from strong acid solutions.

Highly selective removal of thorium from acidic solutions achieved on phosphonic acid functionalized core–shell magnetic nanocomposite: Understanding adsorption and binding mechanisms

Thorium has received widespread attention as potential nuclear fuel alternative for the next-generation thorium-based molten salt reactors. With the growth of nuclear energy, it is needful to exploit magnetic nanomaterials to remove thorium from aqueous solutions, owing to their superparamagnetism and large specific surface energy. Nevertheless, most of magnetic nanomaterials often suffered from low thorium selectivity and poor structural ability in acidic solutions. Herein, a novel core–shell magnetic nanocomposite Fe3O4@SiO2/P (AA-MMA-VPA) possessing phosphonic acid was developed by a controlled radical polymerization of vinylphosphonic acid (VPA) in the presence of Fe3O4 encapsulated by SiO2 (Fe3O4@SiO2). Due to the presence of the high content of phosphonic acid groups and the absence of any universal groups, Fe3O4@SiO2/P (AA-MMA-VPA) displayed exceptional selectivity for thorium in the presence of 11 co-existing cations. The separation factor STh/M value for Fe3O4@SiO2/P(AA-MMA-VPA) concerning all other competing cations surpassed 74.4, and the largest value for STh/M even amounted to 343.5. Further, Fe3O4@SiO2/P (AA-MMA-VPA) possessed a maximum adsorption capacity (qmax) of 485.4 mg g−1 at pH of 3.0, higher than that of other magnetic sorbents. By reason of its core–shell structure, the sorbent possessed an outstanding structure stability even after immersed into HNO3 solution at pH of 0.5 for 72 h. The sorbent could as well be magnetically recouped, and recycled at least six times without evident diminution in sorption amount. The sterling removal performance of the sorbent was assigned to the interaction of thorium with phosphonic acid, corroborated by FT-IR, XPS and DFT method. Thus, this study affords a new viewpoint for exploiting magnetic nanomaterials with sterling acidic resistance for the strongly selective entrapment of thorium from acidic media.

Exploring Quantum Dots Size Impact at Phase Diagram and Electrooptical Properties in 8CB Liquid Crystal Soft-Nanocomposites.

We explore the influence of functionalized core-shell CdSe/ZnS quantum dots on the properties of the host liquid crystal compound 4-cyano-4'-octylbiphenyl (8CB) through electrooptical measurements. Two different diameters of quantum dots are used to investigate the size effects. We assess both the dispersion quality of the nanoparticles within the mixtures and the phase stability of the resulting anisotropic soft nanocomposites using polarizing optical microscopy. The temperature-mass fraction phase diagrams of the nanocomposites reveal deviations from the linear behavior in the phase stability lines. We measure the birefringence, the threshold voltage of the Fréedericksz transition, and the electrooptic switching times of the nanocomposite systems in planar cell geometry as functions of temperature, mass fraction, and diameter of the quantum dots. Beyond a critical mass fraction of the dopant nanoparticles, the nematic order is strongly reduced. Furthermore, we investigate the impact of the nanoparticle size and mass fraction on the viscoelastic coefficient. The anchoring energy at the interfaces of the liquid crystal with the cell and the quantum dots is estimated.

Fabrication of activated carbon fiber functionalized core–shell silver nanoparticles based in situ and low-cost technology for wound dressings with an enhanced antimicrobial activity and cell viability

• A uniformed dispersible & stable coating layer of poly(tannic acid) (PTA) on AgNPs was prepared. • Core–shell AgNPs@PTA with a high yield of 95.8% and minimal toxicity was prepared. • Chitosan improved the half maximal inhibitory concentration of AgNPs@PTA up to 1000 ppm . • A competitive wound dressing was engineered by integrating AgNPs@PTA into activated carbon fiber. Wound dressings are considered to be effective barriers against bacterial attack. They also facilitate wound healing in nursing-management functions. Silver nanoparticles (AgNPs) in wound dressings could overcome the problems associated with bacterial immunity, which is often observed in the use of conventional drugs. In the present work, a high concentration of cost effective and environmentally friendly AgNPs (16.3 ± 3.7 nm) with a uniform core–shell of poly(tannic acid) (PTA) was prepared. The preparation in high yield (95.8%) was based on an autoxidation-reduction reaction that was induced based on pH-responsive reduction affinity of tannic acid (TA). Despite the high antimicrobial activity of the prepared AgNPs@PTA, their cytotoxicity hindered their practical applications. The addition of different concentrations of natural cell viability enhancers, including TA and chitosan, to the prepared AgNPs@PTA solution improved significantly the cell viability. We have succeeded in improving the half maximal inhibitory concentration ( IC 50 ) from 1 to 1000 ppm with minimal cytotoxicity toward L929 cells and 99.99% antimicrobial performance against both E. coli and S. aureus . Finally, the prepared AgNPs@PTA was integrated in an activated carbon fibers for wound-dressing application and exhibited excellent performance when compared with some commercial wound-dressing products.

Application of magnetic nanoparticles modified with L-cysteine for pre-concentration and voltammetric detection of copper(II)

In the present study, magnetic solid-phase extraction (MSPE) was coupled with voltammetric method by using a magnetic carbon paste electrode (MCPE) to determine Cu(II) in aqueous mediums. For this purpose, L-cysteine functionalized core–shell Fe3O4@Au nanoparticles (Fe3O4@Au@L-cysteine) was used as an adsorbent during the extraction step. Following that, the magnetic adsorbent pre-concentrated with Cu(II) was collected on the surface of MCPE for electrochemical detection using differential pulse voltammetry. In the suggested assay, the extraction and determination of copper ions were carried out in a single electrochemical cell. The conditions of extraction and voltammetric determination were explored in detail. Under the optimal conditions (i.e., supporting electrolyte, phosphate buffer; sample pH, 5.0; Fe3O4@Au@L-cysteine amount, 10 mg L-1 (100 μL); agitation time, 120 s; reduction potential, −0.4 V; and reduction time, 90 s), the response currents were linear in 2.0 to 400.0 nmol L-1 Cu(II) concentration range. The limit of detection and reproducibility of the established method were calculated to be 0.4 nmol L-1 and 3.4%, respectively. The applicability of the suggested methodology was confirmed by analysis of Cu(II) in different water samples with recoveries of 96.4–103.6% (n = 3).

Elaborate design of shell component for manipulating the sustained release behavior from core–shell nanofibres

BackgroundThe diversified combination of nanostructure and material has received considerable attention from researchers to exploit advanced functional materials. In drug delivery systems, the hydrophilicity and sustained–release drug properties are in opposition. Thus, difficulties remain in the simultaneous improve sustained–release drug properties and increase the hydrophilicity of materials.MethodsIn this work, we proposed a modified triaxial electrospinning strategy to fabricate functional core–shell fibres, which could elaborate design of shell component for manipulating the sustained-release drug. Cellulose acetate (CA) was designed as the main polymeric matrix, whereas polyethylene glycol (PEG) was added as a hydrophilic material in the middle layer. Cur, as a model drug, was stored in the inner layer.ResultsScanning electron microscopy (SEM) results and transmission electron microscopy (TEM) demonstrated that the cylindrical F2–F4 fibres had a clear core–shell structure. The model drug Cur in fibres was verified in an amorphous form during the X-ray diffraction (XRD) patterns, and Fourier transformed infrared spectroscopy (FTIR) results indicated good compatibility with the CA matrix. The water contact angle test showed that functional F2–F4 fibres had a high hydrophilic property in 120 s and the control sample F1 needed over 0.5 h to obtain hydrophilic property. In the initial stage of moisture intrusion into fibres, the quickly dissolved PEG component guided the water molecules and rapidly eroded the internal structure of functional fibres. The good hydrophilicity of F2–F4 fibres brought relatively excellent swelling rate around 4600%. Blank outer layer of functional F2 fibres with 1% PEG created an exciting opportunity for providing a 96 h sustained-release drug profile, while F3 and F4 fibres with over 3% PEG provided a 12 h modified drug release profile to eliminate tailing–off effect.ConclusionHere, the functional F2–F4 fibres had been successfully produced by using the advanced modified triaxial electrospinning nanotechnology with different polymer matrices. The simple strategy in this work has remarkable potential to manipulate hydrophilicity and sustained release of drug carriers, meantime it can also enrich the preparation approaches of functional nanomaterials.Graphical

Surface chemistry modification of core-shell structured SiO2@LaOF:Eu3+/Li+ nanophosphors for advanced forensic applications

The fabrication of core–shell structured SiO 2 @LaOF:Eu 3+ , Li + nanophosphors and its surface functionalization with oleic acid (OA) by an ultrasonication route are reported. The X-ray diffraction profiles were well indexed to the tetragonal phase of LaOF. The energy band gap of the prepared samples was found in the range ∼4.32–4.21 eV. The morphological studies evidenced the spherical core–shell structure of the prepared nanophosphors. The photoluminescence emission spectra were found to consist of characteristic emission peaks at ∼591 nm ( 5 D 0 → 7 F 1 ), 610 nm ( 5 D 0 → 7 F 2 ), 651 nm ( 5 D 0 → 7 F 3 ) and 707 nm ( 5 D 0 → 7 F 4 ). The enhancement of about 3 times (3-fold) of the photoluminescence emission in the surface functionalized samples is ascribed as due to the efficient ligand energy transfer. The powder dusting technique was adopted to visualize the latent fingerprints using nanophosphor on several porous and non-porous surfaces under sunlight and ultraviolet (254 nm) light excitation. The developed fingerprints display the high sensitivity, selectivity and contrast by enabling up to two levels of friction ridge details. The above-mentioned results revealed that the surface functionalized core–shell structured nanophosphor can be successfully engaged in the area of solid state display and forensic science applications. • Intense red emitting surface functionalized core–shell SiO 2 @LaOF:Eu 3+ ,Li + nanophosphors via grafting oleic acid. • The 3-fold enhancement in the PL emission upon surface functionalized samples due to efficient ligand energy transfer. • Well defined fluorescence fingerprint images on variety of surfaces by revealing type I-II ridge characteristics. • Developed latent fingerprints shows superior contrast, sensitivity, selectivity and negligible background hindrance. • Fabricated invisible security ink and make it highly suitable for dip-pen mode.

PILs modified PMoW on silicon with hierarchical functional structure for ultra-deep oxidative desulfurization

In order to obtain the clean fuel, two types of inorganic–organic hybrid catalysts with core–shell structures have been prepared as efficient and reusable catalysts for oxidative desulfurization, in which ionic liquids (1-vinylimidazole and 4-vinylpyridine) were grafted and polymerized on the surface of silicon through free radical polymerization and polyoxometalates (H3PMo6W6O40, attributed as PMoW) was functionalized on the surface of silicon. The as-prepared catalysts were characterized by FT-IR, UV–Vis, N2 adsorption–desorption, SEM and TEM. It could be proved that these two types of catalysts show high sulfur removal efficiency over 98% in the model fuel with 2000 ppm of DBT under mild reaction condition. The effective catalytic abilities of synthesized catalysts are mainly attributed to the hierarchical functional core–shell structures. The successful preparation of the PILs-polyoxometalates based catalysts with high catalytic activities could provide the demonstration of the application of polymer in oxidative desulfurization.

Advanced approaches of Nanotechnology against COVID-19

The COVID-19 recrudescence has instigated a global demand for productive diagnosis, disseminating millions of people with no initial clear signs of decrement owing to the over extension, long incubation period and lack of established treatments or vaccines. The genome sequence and protein structure of the 2019-novel coronavirus (SARS-CoV-2) which were made available in record time, thus allowed the development of inactivated or attenuated viral vaccines making it a well promising solution to mitigate new viral strains. But along with classical vaccines, if we think about a better solution then the nanoscience and nanotechnology approaches can act as a very good alternative to help the medical, technical and scientific communities to fight the pandemic by evolving more advanced nanoparticles for effective detection, sanitation, therapies and vaccines, as SARS-CoV-2 can also be regarded as a functional core–shell nanoparticle which can interact with and remain attached to a variety of stuffs in its vicinity, preserving its bioactivity simultaneously . Nanoparticles inhibits interaction between angiotensin-converting enzyme 2 (ACE2), receptors with the viral S protein. This field comprises of multidisciplinary prospects chapters like "nano immunity" which help to design materials for immune modulation, which either stimulates or suppresses the immune response to help in giving counter-response against the cytokine storm or in developing vaccines. Additionally, nano sensors can aid in the diagnoses of COVID-19 even on asymptomatic patients. Also, nanoscale fibres can upgrade personal equipment protection and be reused for medical and economic benefits. Here, we review approaches of new applications of nanotechnology against COVID-19 and highlight its role and advanced manufacturing.

Highly efficient extraction of uranium from aqueous solution using imidazole functionalized core–shell sunflower-like superparamagnetic polymer microspheres: understanding adsorption and binding mechanisms

The core–shell sunflower-like magnetic polymer adsorbent Fe3O4/P (MBA-VIM) prepared by distillation–precipitation polymerization not only showed an outstanding adsorption efficiency for uranium, but also could be facilely isolated by using magnetic force.

Fibrinogen aptamer functionalized gold-coated iron-oxide nanoparticles for targeted imaging of thrombi.

Targeting of molecular constituents of thrombi with aptamer functionalized core-shell nanoparticles (CSN) allowed for high resolution clot delineation in T2-weighted magnetic resonance imaging. Meanwhile, the gold-coating demonstrated sufficient contrast capabilities in computed tomography (1697 HU μM-1). This targeted CSN formulation could allow for precise imaging of blood clots at low nanomolar concentrations.

Enhanced thermal conductivity and retained electrical insulation of epoxy composites filled with Cu@BaTiO3 core–shell particles

The application of polymer for thermal interface materials is limited by its low thermal conductivity. In this work, barium titanate coated Cu core–shell particles were prepared and then employed as thermal conductive fillers to reinforce epoxy matrix. The results indicate that thermal conductivity of the Cu@BaTiO3/epoxy composites reaches 1.09 W m-1K−1 at 10 vol% loading, achieving 580% elevation on neat epoxy matrix. Meanwhile, the composites retain high electrical insulation (7.90 × 1013 Ω·cm) due to the existence of insulative BaTiO3 layer on Cu surface. This study will provide a novel insight of the design of functionalized core–shell thermal conductive fillers and construction of high-performance thermal interface materials.

Large‐Scale Synthesis of Functionalized Nanowires to Construct Nanoelectrodes for Intracellular Sensing

AbstractA strategy for one‐pot and large‐scale synthesis of functionalized core–shell nanowires (NWs) to high‐efficiently construct single nanowire electrodes is proposed. Based on the polymerization reaction between 3,4‐ethylenedioxythiophene (EDOT) and noble metal cations, manifold noble metal nanoparticles‐polyEDOT (PEDOT) nanocomposites can be uniformly modified on the surface of any nonconductive NWs. This provides a facile and versatile approach to produce massive number of core–shell NWs with excellent conductivity, adjustable size, and well‐designed properties. Nanoelectrodes manufactured with such core–shell NWs exhibit excellent electrochemical performance and mechanical stability as well as favorable antifouling properties, which are demonstrated by in situ intracellular monitoring of biological molecules (nitric oxide) and unraveling its relevant unclear signaling pathway inside single living cells.

Efficient Dye Degradation via Catalytic Persulfate Activation using Iron Oxide-Manganese Oxide Core-Shell Particle Doped with Transition Metal Ions

Organic-pollutants released into water bodies pose serious concerns because of its detrimental effects in aquatic biota, environment and economy. Water remediation using persulfate based advanced oxidation process is one of the emerging techniques. In this study, we have developed iron oxide-manganese oxide core–shell nanoparticles doped with transition metal ions for the efficient degradation of bromophenol blue dye, for the first time. Here, the transition metal ion doped MnOx shell enables efficient persulfate activation while the magnetic core facilitate in the effective recovery of used particles. The synthesized particles were characterized by X-ray powder diffraction, transmission electron microscopy, X-ray photoelectron spectroscopy and vibrating sample magnetometer. The presence of dopants is found to significantly change the ratio of Mn3+ to Mn4+, reactivity and mobility of lattice oxygen in doped samples. Silver ion doped MnOx showed the highest dye degradation efficiency of ~91% with 1.8 wt% nanoparticles, due to the enhanced reactivity and mobility of lattice oxygen activity of the core–shell nanoparticle in presence of Ag ions in persulfate activation. From the experimental results, the mechanism of activation of persulfate by nanoparticles is elucidated. Our findings provide a new platform for efficient water remediation using dual functional core shell magnetic nanoparticles.

Silk fibroin H-fibroin/poly(ε-caprolactone) core-shell nanofibers with enhanced mechanical property and long-term drug release

The scaffold materials with good mechanical and structural properties, controlled drug release performance, biocompatibility and biodegradability are important tenet in tissue engineering. In this work, the functional core–shell nanofibers with poly(ε-caprolactone) (PCL) as shell and silk fibroin heavy chain (H-fibroin) as core were constructed by emulsion electrospinning. The transmission electron microscopy confirmed that the nanofiber with core–shell structure were successfully prepared. The constructed nanofiber materials were characterized by the several characterization methods. The results showed that ethanol treatment could induce the formation of β-sheet of H-fibroin in composite nanofibers, thus improving the mechanical properties of PCL/H-fibroin nanofiber scaffold. In addition, we evaluated the potential of PCL/H-fibroin nanofiber membrane as a biological scaffold. It was found that PCL/H-fibroin nanofiber scaffold was more conducive to cell adhesion and proliferation with the increment of H-fibroin. Finally, in vitro drug release presented that PCL/H-fibroin core–shell nanofibers could effectively reduce the prophase burst of drug molecules and show the sustained drug release. The PCL/H-fibroin nanofiber scaffolds constructed in this work have good mechanical properties, biocompatibility, and display good potential in biomedical applications, such as drug carriers, tissue engineering and wound dressings, etc.

A facile, two-step synthesis and characterization of Fe 3 O 4 -L Cysteine -graphene quantum dots as a multifunctional nanocomposite.

In this research, a facile, two-step synthesis of Fe3O4–LCysteine–graphene quantum dots (GQDs) nanocomposite is reported. This synthesis method comprises the preparation of GQDs via hydrothermal route, which should be conjugated to the LCysteine functionalized core–shell magnetic structure with the core of about 7.5-nm iron oxide nanoparticle and 3.5-nm LCysteine shell. LCysteine, as a biocompatible natural amino acid, was used to link magnetite nanoparticles (MNPs) with GQDs. X-ray powder diffraction, Fourier-transform infrared spectroscopy, X-ray photoelectron spectroscopy, energy dispersive X-ray were used to investigate the presence and formation of MNPs, {text{L}}_{{{text{Cysteine}}}} functionalized MNPs, and final hybrid nanostructure. Morphology and size distribution of nanoparticles were demonstrated by scanning electron microscopy and transmission electron microscopy. Finally, the magnetic and optical properties of the prepared nanocomposite were measured by vibrating sample magnetometer, ultraviolet–visible, and photoluminescence spectroscopy. The results show that Fe3O4–LCysteine–GQDs nanocomposite exhibits a superparamagnetic behavior at room temperature with high saturation magnetization and low magnetic coercivity, which are 28.99 emu/g and 0.09 Oe, respectively. This nanocomposite also shows strong and stable emission at 460 nm and 530 nm when it is excited with the 235 nm wavelength. The magnetic GQDs structure also reveals the absorption wavelength at 270 nm. Therefore, Fe3O4–LCysteine–GQDs nanocomposite can be considered as a potential multifunctional hybrid structure with magnetic and optical properties simultaneously. This nanocomposite can be used for a wide range of biomedical applications like magnetic resonance imaging (MRI) contrast agents, biosensors, photothermal therapy, and hyperthermia.

Guanidine functionalized core-shell structured magnetic cobalt-ferrite: an efficient nanocatalyst for sonochemical synthesis of spirooxindoles in water.

Core/shell nanoparticles have a wide range of applications in the science of chemistry and biomedicine. The core–shell material can be different and modified by changing the ingredients or the ratio of core to the shell. In this research, a CoFe2O4@SiO2-guanidine nanocomposite was prepared and identified as an efficient catalyst for the one-pot synthesis of spirooxindole derivatives in water under ultrasonic irradiation conditions. The advantages of this method are in its simplicity, saving costs and energy, high yields, short reaction times, environmental friendliness, reusability and easy recovery of the catalyst using an external magnet. The catalyst was characterized by XRD, SEM, TEM, EDX, FT-IR, TGA and VSM techniques.

Functionalized Core–Shell Polystyrene Sphere-Supported Alkaline Imidazolium Ionic Liquid: An Efficient and Recyclable Catalyst for Knoevenagel Condensation

A supported alkaline imidazolium ionic liquid catalyst with an ionic liquid shell and polystyrene core was synthesized. The core–shell structure was achieved by swelling polymerization of 4-vinylbe...

Smart Synthesis of Trimethyl Ethoxysilane (TMS) Functionalized Core-Shell Magnetic Nanosorbents Fe3O4@SiO2: Process Optimization and Application for Extraction of Pesticides.

In the current study, a smart approach for synthesizing trimethyl ethoxysilane–decorated magnetic-core silica-nanoparticles (TMS-mcSNPs) and its effectiveness as nanosorbents have been exploited. While the magnetite core was synthesized using the modified Mössbauer method, Stöber method was employed to coat the magnetic particles. The objective of this work is to maximize the magnetic properties and to minimize both particle size (PS) and particle size distribution (PSD). Using a full factorial design (2k-FFD), the influences of four factors on the coating process was assessed by optimizing the three responses (magnetic properties, PS, and PSD). These four factors were: (1) concentration of tetraethyl-orthosilicate (TEOS); (2) concentration of ammonia; (3) dose of magnetite (Fe3O4); and (4) addition mode. Magnetic properties were calculated as the attraction weight. Scanning electron microscopy (SEM) was used to determine PS, and standard deviation (±SD) was calculated to determine the PSD. Composite desirability function (D) was used to consolidate the multiple responses into a single performance characteristic. Pareto chart of standardized effects together with analysis of variance (ANOVA) at 95.0 confidence interval (CI) were used to determine statistically significant variable(s). Trimethyl ethoxysilane–functionalized mcSNPs were further applied as nanosorbents for magnetic solid phase extraction (TMS-MSPE) of organophosphorus and carbamate pesticides.

Preparation and characterization of electrospun polyethersulfone/polyvinylpyrrolidone-zeolite core–shell composite nanofibers for creatinine adsorption

Dialysis needs innovative dialysis membranes. This method is the primary treatment for patients with kidney failure. Moreover, a wearable artificial kidney (WAK) has been proposed as one of the easy and effective approaches of daily dialysis for patients with the end-stage renal disease (ESRD). Therefore, this study developed a core–shell electrospinning composite nanofiber to remove creatinine for blood purification. Hence, functional core–shell structured composite nanofibers were prepared by electrospinning two polymers and two types of zeolite in a coaxial system. In addition, the blood compatible core–shell structured nanofibers consisted of varying concentrations of polyvinylpyrrolidone and zeolite (PVP and zeolite, shell) and polyethersulfone (PES, core). It has been found that PES/PVP-zeolite core–shell nanofiber could selectively adsorb creatinine. Moreover, scanning electron microscopy (SEM), Energy dispersive spectroscopy (EDS), Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), and X-ray diffraction (XRD) have been used to fully investigate the structure and properties of the obtained core–shell nanofibers. Furthermore, the study considered four important blood compatible factors, including Zeta potential, BSA adsorption, platelet adherent, and cytotoxicity for PES/PVP-zeolite core–shell nanofibers. The EDS results indicated that over 90% of zeolites in the solution has successfully incorporated into the PVP nanofibers. Consequently, performance of the core–shell nanofiber in the retention of bovine serum albumin (BSA) revealed the effectiveness of the negative charge. Finally, the effect of the core–shell nanofiber on the removal of creatinine from solution was evaluated, and it has been found that removal of creatinine significantly increased with the Beta zeolite (4831.19 µg/g). The MTT assay also revealed that core–shell nanofiber with the best performance was biocompatible to L929 fibroblast cells. As a result, no platelet adhesion has been seen on the PES/PVP-Beta zeolite core–shell nanofiber.