Functionality Of System Research Articles

التناص: تحولات الشعرية البلاغية إلى الوظيفة النسقية

The study revolves around the intertextuality orbit in terms of its systemic attachment with cultural critique, where this rhetoric approach assumes a rhetoric capacity that exceeds the deliberative dimensions which are based on showing the poetic aspect of intertextuality and its ability to express the ideas of the text and that is done through creating a new post for it. This post is known as the systemic post and is originally associated with cultural critique and is based on procedural tools designed to create the cultural trick through which the profound meaning is passed. The meaning which Strauss added to the hidden meaning and Iceberger drafted in the underlying structure of the text. The study followed the possibility of this post manifesting itself in Arabic rhetoric and the western intertextuality theory, and did not find a clear impact. Therefore, it assumes that this post is new to intertextuality and this assumption is proven by an applied study which has been conducted on a creative text from the Abbasid Era. This text is Sahl bin Haroun’s letter on stinginess. The research concluded after careful study with results: intertextuality - the rhetorical device known in both Arab and foreign cultures - has a well-known pragmatic function related to the aesthetic and intellectual enrichment of the text linked with various quotations; intertextuality can be utilized in cultural critical studies by establishing the systemic function it possesses. In light of a systemic reading of intertextuality in the message of Sahl ibn Harun on miserliness, it became evident that the writer challenged the image of Arabs by reversing the trait of generosity and placed it on a low moral scale. Therefore, The study recommends following Arabic rhetoric research and studying it within a new vision so that the procedural tools are effective in adopting cultural critique.

Correction of Aero-Optical Effect with Blow–Suction Control for Hypersonic Vehicles

High-speed turbulence induces significant aero-optical effects that severely disrupt the functionality of imaging systems of hypersonic vehicles. In this study, the aero-optical correction of various jet cooling modes is investigated using a Terminal High Altitude Area Defense (THAAD)-like seeker model and the imaging impact of high-speed flow field and flow control on the optical window is analyzed by the Delayed Detached Eddy Simulation (DDES) method. The findings reveal that a jet mode parallel to the window exhibits better cooling effectiveness compared to a perpendicular jet mode along the body axis; however, it introduces additional wavefront distortion, leading to degraded imaging quality. Although micro-vortex generators (MVGs) can reduce density fluctuations near the window from a refractive index perspective, they do not effectively mitigate wavefront distortion or improve window cooling efficiency. Finally, incorporating suction control, a comprehensive flow control solution, significantly improves the flow field structure near the window, resulting in a more uniform temperature distribution and reduced wavefront distortion. Applying this flow control method results in a 14.7% reduction in wavefront distortion at 3 Ma and an approximately 20% maximum value reduction at 5 Ma. This study proposes a novel and comprehensive flow control method to effectively mitigate the aero-optical effect in hypersonic flows, providing a new avenue for subsequent researchers in this field.

Extraction of the Jugular Venous Pulse and carotid profile using a cervical contact plethysmography system

The Jugular Venous Pulse (JVP) is considered a reliable parameter for the assessment of Central Venous Pressure (CVP). Here, the functionality of a cervical contact plethysmography system designed for non-invasive and operator-independent acquisition of the JVP signal, is shown. To validate the signal, it was recorded in supine and sitting positions, together with the reference Electrocardiography (ECG), on 26 healthy subjects. In the supine acquired signal, the characteristic JVP waves (a, c, v) and the negative deflections (x, y) are well recognizable. In the sitting recorded signal, the systolic peak b and the d incisura of the Common Carotid Artery (CCA) waveform are recognized. For each signal, we calculated the Fraction of the Cardiac Cycle (ccf) represented by the time intervals between the JVP peaks and the ECG peaks, in the form: ΔtaP, ΔtcR, ΔtxP, ΔtvT, Δtyv, Δtvx, and Δtxa. The same was done for the CCA waveform, in the form: ΔtbS, ΔtbT, Δtdb, ΔtdS, and ΔtdT. This system could mitigate risks and costs associated with central venous catheterization and its potential extends to applications in telemedicine, sports medicine, and space medicine.

Relationship between obesity, cardiac hemodynamics, and heart failure in adults with coarctation of aorta.

Patients with coarctation of aorta (COA) have arterial stiffening and left ventricular (LV) diastolic dysfunction similar to patients with heart failure with preserved ejection fraction (HFpEF) and obese subjects. However, the relationship between obesity, cardiac hemodynamics, and HF in adults with COA is unknown. The purpose of this study was to compare cardiac hemodynamics and prevalence of HFpEF between COA patients with vs without obesity, and to assess the relationship between obesity and HFpEF in this population. Adults with COA who underwent right heart catheterization were divided into an obese group (body mass index, BMI > 30 kg/m2) or a non-obese group (BMI ≤ 30 kg/m2). We also selected a control group of subjects without structural heart disease and with normal invasive hemodynamics at rest (n = 36). HFpEF was defined as having clinical symptoms of HF (exertional dyspnea or fatigue), LV ejection fraction of at least 50%, and pulmonary artery wedge pressure (PAWP) greater than 15 mm Hg at rest. Of 99 COA patients, 29 (29%) had obesity. The obese COA group had higher right atrial pressure and PAWP, and worse pulmonary and systemic vascular function compared with the non-obese COA group and the control group. The overall prevalence of HFpEF in adults with COA was 32%, and the prevalence was higher in COA patients with obesity (55%) compared with those without obesity (23%). Obesity was associated with HFpEF after adjustment for demographic indices, comorbidities, and vascular function. The abnormal hemodynamics and higher prevalence of HFpEF in COA patients with obesity underscores the need for intervention to address obesity in this population.

Seismic safety evaluation and resilient analysis of nuclear containment based on failure probability

This paper focuses on addressing seismic safety evaluation and resilience analysis of nuclear containment structure. Through the derivation of fragility formulas and the introduction of a new set of limit states (LSs), this paper accomplishes the fragility analysis and assesses failure probabilities comprehensively. Furthermore, safety evaluation and resilience analysis procedures, specifically for nuclear containment, are proposed alongside relevant determination criteria. In order to further improve the seismic performance of nuclear containment, the periodic foundation is analyzed. Theoretical formula is derived to determine the combination of 2 materials (concrete and rubber). Key findings include the safety demonstration of HUALONG 1 through probabilistic reliability analysis, the safety level (Level-I; basic integrity) and resilience level (Level-I). The effectiveness of periodic foundations is confirmed and supported by the average damping rates of concrete and liner strains, which can reach up to 6.154 % and 11.007 %, respectively. This research provides valuable insights for improving the seismic safety and resilience of containment, crucial for ensuring the integrity and functionality of this critical infrastructure system.

The Role of Smart Materials, Sustainable Engineering Practices, and IoT Integration in Advancing Engineering Solutions

This study explores the role of smart materials, sustainable engineering practices, and Internet of Things (IoT) integration in advancing modern engineering solutions. The primary objective is to qualitatively analyze the literature on how these innovative components contribute to the development of efficient, sustainable, and intelligent engineering systems. The research employs a qualitative literature review methodology, examining a broad range of academic articles, technical reports, and case studies related to smart materials, sustainable engineering, and IoT applications. The literature review methodology involves systematically collecting and analyzing relevant scholarly sources to identify key trends and insights. The study categorizes the literature into major themes, such as the properties and applications of smart materials, the principles and benefits of sustainable engineering, and the impact of IoT integration on engineering processes. By synthesizing findings from diverse sources, the research provides a comprehensive overview of the advancements and challenges associated with these technologies. The findings reveal that smart materials, such as shape-memory alloys, piezoelectric materials, and self-healing composites, offer significant potential for enhancing the functionality and durability of engineering systems. Sustainable engineering practices, including the use of renewable materials and energy-efficient designs, are critical for reducing environmental impact and promoting long-term sustainability. IoT integration enables real-time monitoring, data-driven decision-making, and improved system efficiency, thus transforming traditional engineering approaches.

Senso-immunology: the hidden relationship between sensory system and immune system.

The primary sensory neurons involved in pain perception express various types of receptor-type ion channels at their nerve endings. These molecules are responsible for triggering neuronal excitation, translating environmental stimuli into pain signals. Recent studies have shown that acute nociception, induced by neuronal excitation, not only serves as a sensor for signaling life-threatening situations but also modulates our pathophysiological conditions. This modulation occurs through the release of neuropeptides by primary sensory neurons excited by nociceptive stimuli, which directly or indirectly affect peripheral systems, including immune function. Senso-immunology, an emerging research field, integrates interdisciplinary studies of pain and immunology and has garnered increasing attention in recent years. This review provides an overview of the systemic pathophysiological functions regulated by receptor-type ion channels, such as transient receptor potential (TRP) channels in primary sensory neurons, from the perspective of senso-immunology.

Systemic Arterial Function after Multisystem Inflammatory Syndrome in Children Associated with COVID-19

Systemic Arterial Function after Multisystem Inflammatory Syndrome in Children Associated with COVID-19

Advancing psoriasis drug delivery through topical liposomes.

Psoriasis, recognized as a chronic inflammatory skin disorder, disrupts immune system functionality. Global estimates by the World Psoriasis Day consortium indicate its impact on approximately 130 million people, constituting 4 to 5 percent of the worldwide population. Conventional drug delivery systems, mainly designed to alleviate psoriasis symptoms, fall short in achieving targeted action and optimal bioavailability due to inherent challenges such as the drug's brief half-life, instability, and a deficiency in ensuring both safety and efficacy. Liposomes, employed indrug delivery systems, emerge as highly promising carriers for augmenting the therapeutic efficacy of topically applied drugs. These small unilamellar vesicles demonstrate enhanced penetration capabilities, facilitating drug delivery through the stratum corneum layer of skin. This comprehensive review article illuminates diverse facets ofliposomes as a promising drug delivery system to treat psoriasis. Addressing various aspects such as formulation strategies, encapsulation techniques, and targeted delivery, the review underscores the potential of liposomes in enhancing the efficacy and specificity of psoriasis treatments.

People 4.0 — A model for Human-in-the-Loop CPS-based systems

Technology has become ubiquitous, and humans are increasingly dependent on it. Concepts like Smart and Cyber–Physical Systems (CPS), and the Internet of Things (IoT), are frequently used to describe applications and systems that surround us. These concepts commonly encompass applications that are able to sense their environment, collect and process data, make inferences, and communicate with other applications. However, most of the systems that currently exist do not account for human actions and intents, treating humans as mere sources of data. Furthermore, even the few systems that consider the human factor only do so to a very limited extent. On the premise that technology is made by people for people, new human-centric paradigms are needed, in which emotions, human states, and actions can be conveyed into the system. In this paper, we delve into the concept of Human-in-the-Loop Cyber–Physical Systems (HiTLCPS) and the challenges it presents. Building upon this foundation, we propose a novel approach that integrates humans into all phases of the cyber–physical loop. This comprehensive integration entails influencing human emotions and states, and incorporating human actions into the system architecture and functionalities. Finally, to demonstrate the feasibility and effectiveness of our proposed model, we provide concrete implementation examples in this paper. These examples, along with associated case studies, offer insights into how our human-centric paradigm enhances system performance, user experience, and overall effectiveness.

Abnormally glymphatic system functional in patients with migraine: a diffusion kurtosis imaging study

BackgroundThe diffusion tensor imaging analysis along the perivascular space (DTI-ALPS) method has been used to evaluate glymphatic system function in patients with migraine. However, since the diffusion tensor model cannot accurately describe the diffusion coefficient of the nerve fibre crossing region, we proposed a diffusion kurtosis imaging ALPS (DKI-ALPS) method to evaluate glymphatic system function in patients with migraine.MethodsThe study included 29 healthy controls and 37 patients with migraine. We used diffusion imaging data from a 3T MRI scanner to calculate DTI-ALPS and DKI-ALPS indices of the two groups. We compared the DTI-ALPS and DKI-ALPS indices between the two groups using a two-sample t-test and performed correlation analyses with clinical variables.ResultsThere was no significant difference in DTI-ALPS index between the two groups. Patients with migraine showed a significantly increased right DKI-ALPS index compared to healthy controls (1.6858 vs. 1.5729; p = 0.0301). There was no significant correlation between ALPS indices and clinical variables.ConclusionsDKI-ALPS is a potential method to assess glymphatic system function and patients with migraine do not have impaired glymphatic system function.

The Effect of Vitamins on the Immune Systems of Pigs.

In modern pig farming, there are many environmental, physiological or social stresses that weaken the immune response and increase susceptibility to disease. Nutritional management has a significant impact on the efficiency of the immune system in pigs. Among the various nutrients, vitamins have been shown to have specific effects on immune system activity. However, the needs of modern genetic types are not met by the dietary recommendations for vitamins in pig diets. The present study therefore summarises the data on dietary integration with supranutritional doses of vitamins in gestating and lactating sows and post-weaning piglets in terms of the immune response. The present data highlight that high doses of dietary vitamins are an effective way to improve the immune system, antioxidant status and gut health. Further studies are needed to deepen the understanding of the role of dietary supplementation with vitamins in pigs on immune system and gut functionality.

A digital twin framework for efficient electric power restoration and resilient recovery in the aftermath of hurricanes considering the interdependencies with road network and essential facilities

The community's resilience in the face of natural hazards relies heavily on the rapid and efficient restoration of electric power networks, which plays a critical role in emergency response, economic recovery, and the functionality of essential lifeline and social infrastructure systems. Leveraging the recent data revolution, the digital twin (DT) concept emerges as a promising tool to enhance the effectiveness of post-disaster recovery efforts. This paper introduces a novel framework for post-hurricane electric power restoration using a hybrid DT approach that combines physics-based and data-driven models by utilizing a dynamic Bayesian network. By capturing the complexities of power system dynamics and incorporating the road network's influence, the framework offers a comprehensive methodology to guide real-time power restoration efforts in post-disaster scenarios. A discrete event simulation is conducted to demonstrate the proposed framework's efficacy. The study showcases how the electric power restoration DT can be monitored and updated in real-time, reflecting changing conditions and facilitating adaptive decision-making. Furthermore, it demonstrates the framework's flexibility to allow decision-makers to prioritize essential, residential, and business facilities and compare different restoration plans and their potential effect on the community.

State-led carbon data value chain development: a case study of the Republic of Korea

ABSTRACT Introduction: This study investigates the state-led development and management of the value chain for corporate carbon performance data. By tracing the progression path of the carbon data value chain in the Republic of Korea, we aim to assess the functionality of a state-led system. Discussion:The state-driven value chain development provides structured support, particularly in the early development phases. However, it also presents limitations and inefficiencies, including a mismatch between the expansive role of the public sector and the constrained market activities in the downstream segments of the value chain. These dynamics are significantly influenced by country-specific elements such as economic and industrial policies, market receptivity to the net-zero transition, and the decarbonization strategies of both the state and corporations. Conclusion: To advance the carbon data value chain towards greater maturity, we recommend enhancing capacity building, fostering private sector engagement, and improving data transparency, accessibility, and usability.

Pengembangan Aplikasi Stunting Care untuk Pemantauan Pertumbuhan Anak

Recording the results of conventional child growth measurements in the Maternal and Child Health book has long been carried out by health workers and posyandu cadres at the Bontoharu Community Health Center, Selayar Regency, and posyandu cadres in Bontotangnga Village. This form of recording takes quite a lot of time, is prone to errors, and the results do not display attractive visualizations, so a reliable form of recording is needed to monitor children's growth as an effort to prevent and treat stunting. The method used in this community service is Community Based Research (CBR). To overcome the problem of stunting early, the Stunting Care application was developed. Stunting Care is an application for monitoring children's growth periodically by entering data on the child's height and weight. This application will provide predicted results for children, whether they are stunting, at risk of stunting, normal or high normal and is equipped with various features. The Stunting Care application was developed using agile development software engineering methods and through black box testing. The test results of the Stunting Care application are classified as good, as indicated by the system functionality running smoothly.

Involving different stakeholders in prioritising outcomes to assess healthcare systems response for type 1 diabetes management: Using co-creation approaches in Peru.

Engaging diverse stakeholders in developing core outcome sets (COSs) can produce more meaningful metrics as well as research responsive to patient needs. The most common COS prioritisation method, Delphi surveys, has limitations related to selection bias and participant understanding, while qualitative methods like group discussions are less frequently used. This study aims to test a co-creation approach to COS development for type 1 diabetes (T1DM) in Peru. Using a co-creation approach, we aimed to prioritise outcomes for T1DM management in Peru, incorporating perspectives from people with T1DM, caregivers, healthcare professionals, and decision-makers. A set of outcomes were previously identified through a systematic review and qualitative evidence synthesis. Through qualitative descriptive methods, including in-person workshops, each group of stakeholders contributed to the ranking of outcomes. Decision-makers also discussed the feasibility of measuring these outcomes within the Peruvian healthcare system. While priorities varied among participant groups, all underscored the significance of monitoring healthcare system functionality over mortality. Participants recognized the interconnected nature of healthcare system performance, clinical outcomes, self-management, and quality of life. When combining the rankings from all the groups, metrics related to economic impact on the individual and structural support, policies promoting health, and protecting those living with T1DM were deemed more important in comparison to measuring clinical outcomes. We present the first COS for T1DM focused on low-and-middle-income countriesand show aspects of care that are relevant in this setting. Diverse prioritisation among participant groups underscores the need of inclusive decision-making processes. By incorporating varied perspectives, healthcare systems can better address patient needs and enhance overall care quality.

Antioxidant and antibacterial efficiency of the ethanolic leaf extract of Kratom (Mitragyna speciosa (Korth.) Havil) and its effects on growth, health, and disease resistance against Edwardsiella tarda infection in Nile tilapia (Oreochromis niloticus)

The research examined the impact of an ethanolic extract from the leaves of Kratom (Mitragyna speciosa (Korth.) Havil.) on the growth, antioxidant capacity, immune-related gene expression, and resistance to disease caused by Edwardsiella tarda in Nile tilapia (Oreochromis niloticus). The findings revealed that the extract had the important phytochemical content in the extract included total phenolics content, total flavonoids content, vitamin C, and total antioxidant capacity and 5.42 % of the crude extract was mitragynine. The extract demonstrated antioxidant activity, as evidenced by its IC50 values against ABTS and DPPH radicals and its ferric reducing power in vitro. Moreover, the MIC-IC50 value of 0.625 mg/mL indicated that the growth of the bacteria was reduced by approximately 50 %, and the MBC was 2.50 mg/mL against E. tarda. Furthermore, the orally administered Kratom leaf extract to fingerling tilapia for 8 weeks exhibited a noticeable increase in oxidative stress, as demonstrated by the increase in MDA production in the 10 and 25 g/kg groups. It also exhibited an increase in acetylcholinesterase (AChE) activity in muscle tissue at the 50 g/kg group. However, when administered at a feeding rate of 5–10 g/kg feed, the extract showed an increase in the expression of immune-related genes (IL1, IL6, IL8, NF-kB, IFNγ, TNFα, Mx, CC-chemokine, CD4, TCRβ, MHC-IIβ, IgM, IgT, IgD) and enhanced resistance to E. tarda infection in fish. Conversely, administering the extract at 25–50 g/kg feed resulted in contrasting effects, suppressing and reducing the observed parameters. Nevertheless, feeding the extract at all concentrations for 8 weeks did not produce any changes in the histology or systemic functioning of the liver and intestines, as indicated by blood biochemistry. These findings suggest that the ethanolic leaf extract from Kratom has the potential to be used as a substitute for antibiotics in the management of bacterial infections in Nile tilapia culture, with a recommended dosage of 5–10 g/kg feed/day for a maximum of 8 weeks.

Biochemical, Molecular, Postmortem and Histopathological Characterization of Bovine Theilerioses at Different Stages of Production and Reproduction

Theilerosis is the most important common vector (Tick) born and hemoprotozoan diseases (TBDS) which pose a serious threat to the livestock population in terms of mortality, reduced milk yield and lowered draft power. The disease is having impact on biochemistry and systemic functions affecting at different stages of production and reproduction of dairy cattle as well as there is lack of accurate diagnosis of this disease. A total 1900 cases were suspected for theileriosis on the basis of clinical signs and total 950 cases were found positive for theileriosis on the basis of blood smear examination. As per the stages of pregnancy and lactation, the cases were classified as cows in early pregnancy, cows in late pregnancy, cows in post parturient stage, cows in early and late lactation period. Biochemical alterations like increased AST, ALT and BUN level indicating liver and kidney dysfunctions in all the groups and significantly higher in post parturient group. The serum phosphorus, calcium and magnesium level decreased in all the affected groups and mostly in late pregnancy period and post parturient stage indicating metabolic disturbances during the disease which were aggravated during theileriosis. Through molecular diagnosis 114 cows (65.51%) were found positive for T. annulata and 41 cows (22.9%) were found positive for T. orientalis and 19 cows (10.9%) were found positive for both Theileria annulata and Theileria orientalis. Phylogenetic analysis revealed the accession number for Theileria annulata was OQ230445 which is having 100% similarity with puri isolate and 98% similarity with Khorda isolate and the accession number for T. orientalis was OQ 230446 having 85% similarity with Khorda isolate. On necropsy, the animals were weak, debilitated with atrophy of the muscles. In some cases, the liver was enlarged, markedly congested and in some cases yellowish tinged surface and cut edges with distension of gall bladder was evident. Abomasal ulcers were distinct and considered as pathognomonic. On histopathological examination, the liver revealed necrosis of hepatocytes with sinusoidal congestion and infiltration of mononuclear cells. In lymphnode, there was depletion of lymphocytes in lymphoid follicles with congestion and haemorrhage. Pulmonary edema was also evident in few cases. The combined approach involving biochemical, molecular, Post-mortem and histopathological characters were found to be fruitful in diagnosis of the bovine theileriosis at different stages of production and reproduction with optimum specificity.

Terahertz optical pattern recognition with rotation and scaling enhanced by a 3D-printed diffractive deep neural network.

Optical pattern recognition (OPR) has the potential to be a valuable tool in the field of terahertz (THz) imaging, with the advantage of being capable of image recognition with single-point detection, which reduces the overall system costs. However, this application is limited in the traditional OPR that rotation and scaling of the input image will bring about an offset of the recognition spot. Here we demonstrate a full-diffractive method to maintain the recognition spot at a fixed position, even when the input image is rotated or scaled, by using an all-optical diffractive deep neural network. The network is composed of two layers of diffractive optical elements (DOEs) without a 4f-system, and 3D-printed all-in-one. Experimental results show that our device can achieve a stable recognition of the input image regardless of its rotation (from 0° to 360°) or scaling (with a ratio from 1 to 1/1.9). This work is expected to provide enhanced functionality for compact THz systems in imaging and security applications.

NC Meets CN: Porous Photoanodes with Polymeric Carbon Nitride/ZnSe Nanocrystal Heterojunctions for Photoelectrochemical Applications.

The utilization of photoelectrochemical cells (PEC) for converting solar energy into fuels (e.g., hydrogen) is a promising method for sustainable energy generation. We demonstrate a strategy to enhance the performance of PEC devices by integrating surface-functionalized zinc selenide (ZnSe) semiconductor nanocrystals (NCs) into porous polymeric carbon nitride (CN) matrices to form a uniformly distributed blend of NCs within the CN layer via electrophoretic deposition (EPD). The achieved type II heterojunction at the CN/NC interface exhibits intimate contact between the NCs and the CN backbone since it does not contain insulating binders. This configuration promotes efficient charge separation and suppresses carrier recombination. The reported CN/NC composite structure serves as a photoanode, demonstrating a photocurrent density of 160 ± 8 μA cm-2 at 1.23 V vs a reversible hydrogen electrode (RHE), 75% higher compared with a CN-based photoelectrode, for approximately 12 h. Spectral and photoelectrochemical analyses reveal extended photoresponse, reduced charge recombination, and successful charge transfer at the formed heterojunction; these properties result in enhanced PEC oxygen production activity with a Faradaic efficiency of 87%. The methodology allows the integration of high-quality colloidal NCs within porous CN-based photoelectrodes and provides numerous knobs for tuning the functionality of the composite systems, thus showing promise for achieving enhanced solar fuel production using PEC.