Significance. Acute cerebrovascular accident also known as stroke is one of the most common causes of morbidity, mortality and disability in Russia and abroad. In this regard, constant efforts are being undertaken to improve and optimize the diagnosis and provision of emergency specialized medical care to patients with this condition. The purpose of the study is to demonstrate experience of a multidisciplinary team at the regional vascular center, set up at a multidisciplinary medical institution that also operates in an ambulance mode, City Clinical Hospital named after M.P. Konchalovsky of the Moscow Healthcare Department. Material and methods. The material of the study was performance evaluation of a multidisciplinary team at the City Clinical Hospital named after M.P. Konchalovsky for the period from 2019 to 2022 to optimize the diagnosis and choice of treatment for patients with stroke. Results. Optimizing routing of patients with suspected stroke upon admission made it possible to save time and reduce the timespan before the thrombolytic therapy or thromboextraction is initiated. The introduction of a multidisciplinary team made it possible to reduce time for making the right decisions related to the treatment of patients with stroke. The change in the concept of diagnosing and treating patients with stroke from “sequence” to “parallelism” has significantly reduced the time spent on making a diagnosis, initiating thrombolytic therapy, thromboextraction if necessary, and reducing disability and mortality in patients with stroke. Conclusion. Specialized vascular centers and departments have proven to be effective in improving the diagnosis, treatment and functional performance of patients with stroke. However, the lack of regulatory documents requires further development of algorithms of the work of multidisciplinary teams. The introduction of multidisciplinary teams at the Regional Vascular Center of the "stroke network" made it possible to: achieve medical efficiency by reducing the "door-to-needle" time, mortality and severity of disability indicators; attain cost effectiveness by reducing length of hospital stay and cost of inpatient treatment of patients with stroke. Scope of application. Public health and health organization