Functional Harmony Research Articles

Full mouth rehabilitation of a patient with Restorative Space Issues and loss of VDO by replacing maxillary arch with fixed prosthesis opposing a flexible removable partial denture in mandibular arch: A case report

Primary objective of full mouth rehabilitation is the restoring the teeth to optimal physiological and functional balance . Planning a comprehensive course of treatment for a number of missing teeth can be difficult, particularly when the vertical dimension (VD) of the occlusion is reduced. In this case report the sequential methodical interdisciplinary approach employed to treat multiple missing teeth with a loss of VD is described. The patient receives a temporary prosthesis by increasing the vertical dimension.A definitive reconstruction using a fixed prosthesis in the maxillary arch and mandibular ant region and a flexible partial denture in the mandibular arch was carried out following validation of the newly established restorative vertical dimension. A dentist can improve a patient's quality of life by providing functional harmony and aesthetic comfort through appropriate diagnosis and treatment planning

Modified Combined Impression Technique for Cawood & Howell Class V/VI Mandibular Ridges: A Case Report

Geriatric prosthodontic rehabilitation with compromised residual ridge has become challenging, the principal concern being rejuvenating and maintaining complex stomatognathic functional harmony with severe residual ridge resorption (RRR). Modification of contemporary treatment techniques should be considered to achieve a patient’s functional and esthetic requirements. Contemporary prosthodontics utilizing combination of Neutral zone technique (NZ) and all green impression (AGI) for the management of Cawood & Howell Class V/VI (severely resorbed) ridges are innovative techniques for the construction of removable prosthesis with a profound effect in denture stability and retention, particularly in mandible. NZ implies the principle of synergistic activity of Oro-muscular function in denture stability by arranging the prosthetic teeth within the neutral zone area, hence preventing their interfere with the oro-muscular function, while AGI aimed at achieving prosthesis retention through functional moulding and the viscosity of impression material helps disseminate the forces transmitted to the denture-bearing area reducing the potential for discomfort arise from the soft tissue folds over atrophic ridge. This case report attempts to present a combination of modified impression techniques utilizing all green impression techniques and neutral zone techniques in a 66-year-old patient for C&H Class V mandibular ridge. The goal of this technique is to provide optimal stability covering the maximum denture bearing area and selectively distributing the pressure and to produce a denture molded by oro-muscular function in harmony with its surrounding structures thereby enhancing stability and retention.

Role of Sheeta Upanaha in the Management of Vipadika – A Case Study

Skin is the mirror which reflects the harmony of Internal functions of body. Psoriasis is a non-infective inflammatory, Proliferative, Chronic skin disease in which there are scaly papules and plaques that can involve any part of body. Palmoplantar psoriasis refers to psoriasis that develops on palms and soles. Vipadika is included in Kshudra kusta having sign and symptoms similar to Palmoplantar psoriasis. In this case study, A 65-year-old male patient a known case of Palmoplantar psoriasis approached with symptoms of Scales and fissures over both palms and soles with Pain, Severe itching and burning sensation for the past 1year. After clinical examination and history of the patient he was advised, Deepana & Pachana, Shamana Snehapana and Seetha Upanaha as module of treatment. Even though treatment principles such as Deepana, Pachana, Shamana Snehapana might have helped in the overall result, but it was Seetha Upanaha Chikitsa observed to be quite significant in this case, as patient started feeling better after starting of Seetha upanaha. After implementation of treatment plan patient has become completely symptom free and there was no recurrence even after six months.

Soft-tissue paradigm: A review

Facial esthetics and balanced facial proportions are the expectations of the orthodontic patient. Promising and achieving the desired facial esthetic outcome, with functional harmony are the major orthodontic challenges. A detailed study of facial hard and soft-tissue structures is required for an orthodontist to evaluate, diagnose, and treat the chief complaints of an individual orthodontic patient. Orthodontic treatment has evolved from the angles paradigm to the soft-tissue paradigm. Evaluation in terms of facial esthetics requires a thorough understanding of the concept of the soft-tissue paradigm. This review article summarizes existing major facial esthetic parameters comprehensively and will also act as a guide for the detailed scientific evaluation of soft-tissue proportions in achieving treatment goals in orthodontics and dentofacial orthopedics.

Neo-Riemannian Analysis in the System of Theoretical Views of Richard Cohn

The purpose of the article is to highlight the main principles of the Neo-Riemannian method of analysis in the system of Richard Cohn’s theoretical views. The methodological basis of the work is a structural analysis and a special Neo-Riemannian method of pitch structure analysis, which consists of a set of analytical procedures aimed at identifying and graphically highlighting triadic transformations and projecting harmonic objects onto the hexatonic system of co-cycles with a description of the relationships between them. The scientific novelty of the article consists in bringing into Ukrainian musicology the methods of analysis of pitch structures proposed by the North American theorist R. Cohn, the presentation of the main works and theoretical innovations of the researcher. Conclusions. The Neo-Riemannian theory of the analysis of triadic pitch structures is one of the leading contemporary concepts developed by North American musicology on the basis of a neo-positivist approach. The theory is based on the idea of transforming a sound object (triad), which was laid down in the works of the German theorist Hugo Riemann. This idea was continued in the researches of the first Neo-Riemannian theorists – D. Lewin and B. Hyer – primarily in the form of three triadic transformations, designated as Neo-Riemannian Operations. The Neo-Riemannian approach offers an understanding of the triad as a structural unit, demonstrating the expediency of its use both in works with late romantic harmony and outside the context of tonal music, where the triad exhausts its potential as an element of functional harmony. The consideration of individual provisions of the Neo-Riemannian method in the works by R. Cohn (among them voice-leading parsimony, the hexatonic system, combined transformations) made it possible to see the technological possibilities of the method, which contribute to the understanding of the interrelationship of triads without focusing on the tonal-functional connection of chords and the central element of pitches systems. Keywords: Neo-Riemannian theory of analysis of triadic pitch structures, triadic transformations, voice-leading parsimony, hexatonic system, combined transformations, Richard Cohn’s theoretical system.

Regulatory TR3-56 Cells in the Complex Panorama of Immune Activation and Regulation.

The interplay between immune activation and immune regulation is a fundamental aspect of the functional harmony of the immune system. This delicate balance is essential to triggering correct and effective immune responses against pathogens while preventing excessive inflammation and the immunopathogenic mechanisms of autoimmunity. The knowledge of all the mechanisms involved in immune regulation is not yet definitive, and, probably, the overall picture is much broader than what has been described in the scientific literature so far. Given the plasticity of the immune system and the diversity of organisms, it is highly probable that numerous other cells and molecules are still to be ascribed to the immune regulation process. Here, we report a general overview of how immune activation and regulation interact, based on the involvement of molecules and cells specifically dedicated to these processes. In addition, we discuss the role of TR3-56 lymphocytes as a new cellular candidate in the immune regulation landscape.

When in Rome: A Meta-corpus of Functional Harmony

When in Rome: A Meta-corpus of Functional Harmony

A Systematic Generalisation of Chord Configuration Methods in Harmonic Writing Based on a Big Data Context

Abstract In this paper, we systematically summarize the chord configuration method in harmonic writing, start from the connection principle of functional harmony, and use the knowledge of harmonic theory to research and explain the harmonic variability writing and chord configuration method. Secondly, based on big data algorithms, it is proposed that according to the chord composition law and progression logic, a chord system construction objective function is proposed, and a dynamic planning algorithm for automatic chord arrangement is designed to realize automatic chord arrangement by machine. Then, after reducing the chord repetition rate of the generated music, it was found that the ideal style type of music could not be achieved. For this problem, a hidden Markov-based chord auto-configuration model is proposed for optimization and experimental analysis of the chord configuration method in harmonic writing is carried out. The results show that the emotional response of the major triad music fragment with an octave decrease in overall pitch is a positive emotion, and the intensity of the emotion is significantly reduced compared to the major triad with no pitch change. The emotional response to the music fragment of the major triad with an octave increase in overall pitch was positive, and the emotional intensity of the major triad with no pitch change was significantly increased. This study improved students’ musical aesthetics, cognitive abilities, and experiences.

방송통신위원회의 독립성과 중립성에 관한 연구

The Korea Communications Commission was established to deal with new problems occurring in the face of changes in the media environment, specifically the blending of broadcasting and communications, and it can be considered an independent administrative agency. Such organizations characteristically have an autonomous aspect that is distinguishable from the hierarchy of traditional administrative organizations due to the professionalism and the neutrality that is expected in the execution of their respective fields, though the specific forms may not all be the same considering they may be shaped by the historical experience of individual countries in order to meet realistic needs. Regarding policies related to broadcasting and communications, the establishment and operation of the Korea Communications Commission is significant in terms of the guarantee of constitutional freedom of speech and the press. The Korea Communications Commission is expected to perform an autonomous function in its particular business area, but with the establishment of a relationship with the existing administrative system, it will take more than simply emphasizing that independent characteristic to achieve the best results. Although one aspect of this independent characteristic is to keep an already powerful government in check, realizing functional harmony with the government’s organizational system should also be considered given that the smooth execution of the institution’s original duties is also the main purpose of its establishment. The Commission must implement specific measures to strengthen professionalism to enhance its independence and neutrality, along with securing the democratic legitimacy of its institutional composition.

Harmony of Sacred Numbers Functions in the Works of Belles-Lettres from Islamic Perspective

Harmony of Sacred Numbers Functions in the Works of Belles-Lettres from Islamic Perspective

Ocular surface immune cell diversity in dry eye disease.

Dry eye disease (DED) is a multifactorial chronic ocular surface inflammatory condition. Disease severity has been directly related to the immuno-inflammatory status of the ocular surface. Any perturbation in the orchestrated functional harmony between the ocular surface structural cells and immune cells, both resident and trafficking ones, can adversely affect ocular surface health. The diversity and contribution of ocular surface immune cells in DED have been of interest for over a couple of decades. As is true with any mucosal tissue, the ocular surface harbors a variety of immune cells of the innate-adaptive continuum and some of which are altered in DED. The current review curates and organizes the knowledge related to the ocular surface immune cell diversity in DED. Ten different major immune cell types and 21 immune cell subsets have been studied in the context of DED in human subjects and in animal models. The most pertinent observations are increased ocular surface proportions of neutrophils, dendritic cells, macrophages, and T cell subsets (CD4+; CD8+; Th17) along with a decrease in T regulatory cells. Some of these cells have demonstrated disease-causal association with ocular surface health parameters such as OSDI score, Schirmer's test-1, tear break-up time, and corneal staining. The review also summarizes various interventional strategies studied to modulate specific immune cell subsets and reduce DED severity. Further advancements would enable the use of ocular surface immune cell diversity, in patient stratification, i.e. DED-immunotypes, disease monitoring, and selective targeting to resolve the morbidity related to DED.

The harmony of form and function in DNA nanotechnology.

The harmony of form and function in DNA nanotechnology.

Restoring esthetics and functional harmony in a patient with attrited dentition using Hobo twin-stage technique

Restoring esthetics and functional harmony in a patient with attrited dentition using Hobo twin-stage technique

Hearing functional harmony in jazz: A perceptual study of music-theoretical accounts of extended tonality

Functional harmony is an integral part of many repertoires in the Western musical practices, including both diatonic and extended tonality. In the latter context, music-theoretical accounts suggest that the three octatonic equivalence classes (OECs) consisting of pitch-classes related by stacked minor-third intervals may be associated with tonic (T), dominant (D), and subdominant (S) functions. Whether this theoretical description of music is also relevant to the perception of music has not yet been tested empirically. In this study, 100 participants familiar with Western repertoires were presented with jazz chord progressions containing chord substitutions. When each stimulus had been played, participants predicted how many more chords they would have expected to hear before the progression could reach a plausible conclusion. We computed the similarity of responses for pairs of stimuli containing different harmonic substitutions and modeled such similarity values based on different measures of harmonic relatedness between substitutions. Data show that the OEC membership of substitutions strongly predicts the similarity of participants’ completion ratings. Bayesian mixed-effects modeling of similarity values further showed a categorical distinction between D and S as functional categories, on one hand, and T, on the other hand. The data also appear to reflect the prevalent influence of rock and pop repertoires on the participants, encouraging further research into the influence of stylistic diversity and musical expertise. Overall, results contribute to the characterization of listeners’ implicit knowledge of the principles of harmonic structure in extended tonality and support the relevance of OECs not only as descriptors of extended-tonal compositional practices but also parsimonious predictors of perceived functionality.

Functional harmony ontology: Musical harmony analysis with Description Logics

Symbolic representations of music are emerging as an important data domain both for the music industry and for computer science research, aiding in the organization of large collections of music and facilitating the development of creative and interactive AI. An aspect of symbolic representations of music, which differentiates them from audio representations, is their suitability to be linked with notions from music theory that have been developed over the centuries. One core such notion is that of functional harmony, which involves analyzing progressions of chords. This paper proposes a description of the theory of functional harmony within the OWL 2 RL profile and experimentally demonstrates its practical use.

Exploring the eukaryotic Yip and REEP/Yop superfamily of membrane-shaping adapter proteins (MSAPs): A cacophony or harmony of structure and function?

Polytopic cargo proteins are synthesized and exported along the secretory pathway from the endoplasmic reticulum (ER), through the Golgi apparatus, with eventual insertion into the plasma membrane (PM). While searching for proteins that could enhance cell surface expression of olfactory receptors, a new family of proteins termed “receptor expression-enhancing proteins” or REEPs were identified. These membrane-shaping hairpin proteins serve as adapters, interacting with intracellular transport machinery, to regulate cargo protein trafficking. However, REEPs belong to a larger family of proteins, the Yip (Ypt-interacting protein) family, conserved in yeast and higher eukaryotes. To date, eighteen mammalian Yip family members, divided into four subfamilies (Yipf, REEP, Yif, and PRAF), have been identified. Yeast research has revealed many intriguing aspects of yeast Yip function, functions that have not completely been explored with mammalian Yip family members. This review and analysis will clarify the different Yip family nomenclature that have encumbered prior comparisons between yeast, plants, and eukaryotic family members, to provide a more complete understanding of their interacting proteins, membrane topology, organelle localization, and role as regulators of cargo trafficking and localization. In addition, the biological role of membrane shaping and sensing hairpin and amphipathic helical domains of various Yip proteins and their potential cellular functions will be described. Lastly, this review will discuss the concept of Yip proteins as members of a larger superfamily of membrane-shaping adapter proteins (MSAPs), proteins that both shape membranes via membrane-sensing and hairpin insertion, and well as act as adapters for protein-protein interactions. MSAPs are defined by their localization to specific membranes, ability to alter membrane structure, interactions with other proteins via specific domains, and specific interactions/effects on cargo proteins.

Orthognathic surgery and obstructive sleep apnea syndrome: a systematic review

Introduction: In the scenario of Obstructive Sleep Apnea Syndrome (OSAS), Orthognathic Surgery (OS) corrected the deformities of the maxillary and mandibular bones OS has evolved a lot in the last two decades. OS treats patients with moderate and severe facial deformities, allowing the achievement of functional balance and harmony in facial aesthetics. Objective: To present the current findings of the importance of orthognathic surgery in the treatment of obstructive sleep apnea syndrome. Methods: A total of 78 articles were found involving mesh terms about Orthognathic Surgery and OSAS. Initially, was held the exclusion of existing title and duplications following the interest described in this work. After this process, the summaries were evaluated, and a new exclusion was held. Thus, 20 articles were included and discussed in this study. Major considerations and conclusion: In recent years, with the involvement and deepening of oral medicine in the diagnosis and treatment of OSAS, the role of OS in OSAS has become increasingly recognized. Early appropriate diagnosis and treatment can significantly improve patients' quality of life, reduce sudden death, and prevent various complications. OS corrects maxillofacial deformities through an incision of the upper and lower jaws, which has a significant relief effect on the symptoms of OSAS in patients with upper airway stenosis, especially in small mandibular patients.

From Copper Tolerance to Resistance in Pseudomonas aeruginosa towards Patho-Adaptation and Hospital Success.

The hospital environment constitutes a reservoir of opportunistic pathogens responsible for healthcare-associated infections (HCAI) such as Pseudomonas aeruginosa (Pa). Pa persistence within technological niches, the increasing emergence of epidemic high-risk clones in HCAI, the epidemiological link between plumbing strains and clinical strains, make it a major nosocomial pathogen. Therefore, understanding the mechanisms of Pa adaptation to hospital water systems would be useful in preventing HCAI. This review deciphers how copper resistance contributes to Pa adaptation and persistence in a hospital environment, especially within copper water systems, and ultimately to its success as a causative agent of HCAI. Numerous factors are involved in copper homeostasis in Pa, among which active efflux conferring copper tolerance, and copper-binding proteins regulating the copper compartmentalization between periplasm and cytoplasm. The functional harmony of copper homeostasis is regulated by several transcriptional regulators. The genomic island GI-7 appeared as especially responsible for the copper resistance in Pa. Mechanisms of copper and antibiotic cross-resistance and co-resistance are also identified, with potential co-regulation processes between them. Finally, copper resistance of Pa confers selective advantages in colonizing and persisting in hospital environments but also appears as an asset at the host/pathogen interface that helps in HCAI occurrence.

Laurie Anderson’s Transmedia Storytelling

Laurie Anderson’s Transmedia Storytelling

Borrowed and Original Techniques in the Trio by Leonid Hrabovsky

Relevance of the study. During several years that preceded the creation of the Trio (1964), Leonid Hrabovsky wrote many other works in various genres and forms, ranging from suites and a sonata for solo instruments, a song cycle, and a cappella choruses, to large-scale compositions for orchestra and for mixed choir with orchestra, and even two one-act operas (piano scores). The composer’s stylistic priorities had been rapidly and strikingly evolving from “social realism with a human face” as evident in the Four Ukrainian Songs, towards a much more radical “sharp” expressionism and constructivism. This evolution caused the necessary changes in the techniques utilized by the composer. Hrabovsky was deeply impressed by the article Genealogia nowej muzyki (Genealogy of the new music) of the Polish musicologist Tadeusz Zieliński that was published in the magazine Ruch muzyczny, n. 20–21, 1963. Zieliński stated that, after historical periods of monody, polyphony and functional harmony, a new sonoric and timbral era had come. These ideas inspired Hrabovsky to move towards the radical avant-garde.
 The object of this research is the Trio by Leonid Hrabovsky.
 The purpose of the study is to reveal the inherent features that differentiate the piece from other avant-garde works of the early 1960s.
 Methods of research include technical analysis of the musical form and its dependence upon the pitch organization of the work, as well as comparative analysis.
 The results and conclusions. Being composed during several days in the spring of 1964, Trio became the first piece of Hrabovsky’s written in a definitely avant-garde style. It was premiered in 1966 and since then has become one of the composer’s most frequently performed works. The reason for such a success lies in the original concept of the piece that essentially differs from the other avant-garde works of that time. When discussing Trio, Hrabovsky always stresses the influence of the Polish avant-garde music attracting him during that period. Indeed, he borrowed a lot of devices from Miniatures for violin and piano by Krzysztof Penderecki, a score Hrabovsky knew and studied at that time. However, a comparative analysis of the two works reveals serious differences between them. While Penderecki operated with purely timbral (sonoric) objects and did not pay special attention to the pitch organization, Hrabovsky composed almost a classical three movement suite with the first movement in a ternary form and the last movement in the binary form. The classical principles of the pitch organization and the distribution of the pitch structures in Trio are similar to those in tonal music. These principles have been unusually applied to the sound material that has nothing in common with tonality. A combination of the traditional and new approaches to the form provided Hrabovsky’s Trio with unique qualities which made it not only an interesting artifact of the avant-garde period but one of the most valuable and artistically perfect works in the Ukrainian chamber music.