Full-term Girl Research Articles

Four siblings with hepatic disease leading to cirrhosis.

CIRRHOSIS been frequently reported in children, and reference has often been made to multiple cases in families. However, the familial and genetic aspects of cirrhosis are not generally recognized. It is the purpose of this communication, first, to report the histories of four sisters all of whom were seen by one of us (L. F. R.) and who died within the first three months of life with postmortem findings of cirrhosis of the liver, and second, to evaluate briefly familial factors underlying cirrhosis of the liver in children. REPORT OF CASES The parents of these children were of primarily Scandinavian extraction, unrelated by blood, and in good health. The mother's first pregnancy resulted in a boy infant who showed no abnormalities and is now living and well. Case1.—As a result of the second pregnancy, which was normal, a full-term girl was born Jan. 4, 1934, with a birth weight

THE KLIPPEL-FEIL SYNDROME

Hitherto, reports of cases of the Klippel-Feil syndrome have considered only the clinical manifestations. These have been described as shortening of the neck, low hair line, limitation of movements of the head, abnormal associated or mirror movements, clumsiness of the hands, disturbances of deep sensation in the hands and forms of ocular palsy, affecting chiefly the third cranial nerve. Roger, Arnaud and Audier1discussed the nervous manifestations associated with the Klippel-Feil syndrome, reporting an instance of their own and reviewing in detail the cases reported up to 1934. The following case is described, because pathologic reports on the changes in the spinal cord are lacking. REPORT OF A CASE History. —A deformed, full term girl (fig. 1) was delivered from a primipara aged 20, who had had a profuse vaginal discharge during the entire pregnancy and toxemia of nephritic origin in the last trimester. The general appearance of the

SECOND BIRTH WITH SPINA BIFIDA

To the Editor: —InThe Journal, March 24, page 997, it is stated that there is on record one case of spina bifida in a subsequent pregnancy. I know of a case in which a young primipara was delivered of a full term girl with a spina bifida in June, 1922. This child died at about the age of 7 months. In 1926 the woman became pregnant again and was delivered at term of another spina bifida baby. This child was operated on and died at about six weeks.

EARLY PREGNANCY FOLLOWING DELIVERY

To the Editor: —Mrs. C., aged 21, white, American, an only child, menstruated last, Sept. 22, 1923, and I delivered her of a normal full term girl baby, July 7, 1924, at White Cross Hospital. She left the hospital on the fifth day by ambulance, had a normal puerperium, and the lochia serosa stopped on the thirteenth day. I saw her in January this year, and she was again pregnant and showing some early signs of toxemia, which were readily relieved by diet, rest, etc., and, April 21 this year, I delivered her of twin girls, one weighing 5 pounds (2.3 kg.) and the other, 4 pounds, 12 ounces (2.1 kg.). The babies were normal and nursed the breast at the end of twelve hours. They left the hospital at the end of two weeks, having gained 6 and 8 ounces, respectively. If these babies were premature, it was slight,