Full Removal Research Articles

Nose Reconstruction Using Bilobed Flap: A Case Report

This document illustrates the formatting process for authors, who would be preparing their papers for publication in the International Journal of Scientific Advances (IJSCIA). It behooves the prospective authors the skillset, scientific or scholarly acumen and wherewithal to ensure that their manuscript contents are original and have never been submitted to other journals while under review in the IJSCIA. Background: Basal cell carcinoma (BCC) is a slow-growing, locally destructive malignant skin tumor. The nasal location is considered a high-risk feature of BCC because of its anatomical features and problems in identifying the tumor preoperatively. Surgery is the cornerstone of nasal BCC treatment and various techniques have been developed to combine full 3D tumor removal with good aesthetic and functional results. Case Presentation: We report a circular black discoloration of a 64-year-old male patient on the left side of the nose within 2 years. The patient was scheduled for surgical removal and reconstruction of the defect using a bilobed flap. The flap consists of two lobes with a common semicircular base marked around the transverse portion of the nasalis muscle and its aponeurosis. The flap then removes the skin from the triangular peninsula at the base of the defect. After removal, the flap is moved into the defect and placed with 5-0 Prolene with a simple suture. Conclusion: The bilobed flap has multipurpose in all ways. The main benefit of this flap include the similarity color and texture relative to the defect site, ease of reproducibility, low complication rates, and the ability to design it in different sizes and tissue compositions.

Quality and Tool Stability Improvement in Turning Operation Using Plastic Compliant Damper

The major hindrance for any production industry in obtaining higher yield is the lack of achieving full material removal rate in the machine tools. If achieved, the surface quality of the machined works will be compromised. An attempt was made in this work to reduce the compromise of surface finish by integrating a plastic compliant damper that is capable of reducing the effects of unwanted vibrations generated during the machining process. The damper is designed to degenerate the effects of vibration and thereby improve product finish. It is made of acrylonitrile butadiene styrene by fused deposition modelling (an additive manufacturing technique). Measuring the vibration and cutting force is indirectly related to finish in product and tool wear rate. The stability of tool is improved greatly by the new compliant damper possessing displacement resistance. The effect of variation in cutting conditions on the performance of conventional rubber damper and plastic compliant damper was analyzed. The highest speed, feed rate, and depth of cut of 540 rpm, 0.02 mm/s, and 1.5 mm, respectively, found to be cutting condition at which imparted minimum surface roughness values of 2.80 μm and 0.52 μm with conventional rubber damper and plastic compliant damper, respectively. The speed and feed rate and depth of cut are found to be important parameters while studying surface roughness. The peak surface roughness is reduced by 48% by using the proposed compliant damper.

Comparative analysis of absorption capacity of Cr(VI) polyaniline and cellulose/polyaniline composites synthesized in aqueous solutions of organic acids

Samples of polyaniline (PAn) doped by different organic acids, namely PAn-FA, PAn-AA, PAn-OA, and PAn-CA, were synthesized by oxidation of aniline (An) with ammonium peroxydisulfate in the 0.5 M aqueous solutions of formic (FA), acetic (AC), oxalic (OA), and citric acids (CA) respectively. Samples of composites of cellulose (Cel) with doped polyaniline (Cel/PAn-FA, Cel/PAn-AA, Cel/PAn-OA, and Cel/PAn-CA)were produced by the same method under the presence of a suspension of microfibrillar bleached cellulose in the reaction mixture. The mass ratio of An : Cel was 1 : 1. The structure of obtained samples was studied using X-ray diffraction, FTIR spectral analysis, and scanning electron microscopy. Adsorption capacity as concerns Cr(VI) by produced samples of both individual polyanilines and composites and adsorption kinetics has been studied by electronic (UV) and fluorescence X-ray spectroscopy and also X-ray energy dispersion analysis methods. Practically full removal of Cr(VI) ions (98–100 %) of such investigated samples of PAns and its composites has been determined. The adsorption kinetics is well described by equations of pseudo first and second orders. According to the results, the Langmuir and Freundlich adsorption isotherms are plotted. It was found that the process of adsorption Cr(VI) ions by doped samples of PAn and Cel/PAn accords to adsorption model of Langmuir. It has been shown, that adsorbed chromium remains in the samples of adsorbents in the form of chromium (III). Keywords : polyaniline, cellulose, composites, structure, Cr(VI), adsorption.

Evaluation of Kinetic Pseudo-Order in the Photocatalytic Degradation of Ofloxacin

Ofloxacin is a highly efficient and widely used antibiotic drug. It is classified as a refractory pollutant due to its poor biodegradability. Consequently, it is commonly found in water sources, requiring efficient methods for its removal. Advanced oxidation processes (AOPs) offer efficient alternatives since those yield complete degradation not achieved in adsorption or membrane processes. Previous studies suggest ofloxacin degradation follows a pseudo-first or -second order processes, whereas for full removal of refractory pollutants—lower pseudo-orders are required. Monitoring the actual “pseudo-order” degradation kinetics of ofloxacin is needed to evaluate any proposed AOP process. This study presents a simple procedure to evaluate pseudo-orders of AOPs. Photolysis of 20 μM ofloxacin solutions follow pseudo-zero order kinetics, with half-life times (t1/2) of approx. 60 min. TiO2 heterogenous catalysts have been shown to have no influence at low concentrations (0.2 mg L−1), but a significant reduction of half-life time (t1/2 = 20 min) and increase in pseudo-order (0.8) is measured at 2.0 mg L−1. Similar results are obtained with homogenous catalysis by 2.0 mg L−1 H2O2. The combination of H2O2 and TiO2 catalysts shows additional reduction in half-time life with increase in the pseudo-order to 1.2. The conclusions are (1) heterogenous and homogenous photocatalysis can effectively degrade ofloxacin, (2) combined photocatalysis yields higher pseudo-order, being less prone to achieve full removal, and (3) analysis of specific pseudo-orders in AOPs of refractory pollutants helps to further elucidate the efficiency of the processes.

Mycoplasma decontamination in Chlamydia trachomatis culture: a curative approach.

Mycoplasma contamination of cell culture represents a serious problem in research and decontamination from cell-propagated obligate intracellular bacteria has proven challenging. Here, we presented an optimized protocol to remove Mycoplasma from contaminated Chlamydia trachomatis culture. A stepwise procedure of Mycoplasma removal entails (i) incubation in nonionic detergent-containing solution and (ii) separation of viable chlamydial organisms by fluorescence-activated cell sorting (FACS), followed by subcloning using a focus-forming assay. We also adapted a polymerase chain reaction (PCR) assay using paired universal and Mycoplasma-specific primers, which are distinguishable from the C. trachomatis counterparts, in combination with Sanger sequencing to determine the presence of mycoplasmas' 16S rRNA genes. These integrated approaches allow for full removal of Mycoplasma, as verified by the improved PCR assay, without compromising the capacity of viable C. trachomatis to adapt to new infection in epithelial cells. Some pitfalls during the Mycoplasma decontamination process are discussed.

Oligonucleotide conjugated antibody strategies for cyclic immunostaining

A number of highly multiplexed immunostaining and imaging methods have advanced spatial proteomics of cancer for improved treatment strategies. While a variety of methods have been developed, the most widely used methods are limited by harmful signal removal techniques, difficulties with reagent production and antigen sensitivity. Multiplexed immunostaining employing oligonucleotide (oligos)-barcoded antibodies is an alternative approach that is growing in popularity. However, challenges remain in consistent conjugation of oligos to antibodies with maintained antigenicity as well as non-destructive, robust and cost-effective signal removal methods. Herein, a variety of oligo conjugation and signal removal methods were evaluated in the development of a robust oligo conjugated antibody cyclic immunofluorescence (Ab-oligo cyCIF) methodology. Both non- and site-specific conjugation strategies were assessed to label antibodies, where site-specific conjugation resulted in higher retained binding affinity and antigen-specific staining. A variety of fluorescence signal removal methods were also evaluated, where incorporation of a photocleavable link (PCL) resulted in full fluorescence signal removal with minimal tissue disruption. In summary, this work resulted in an optimized Ab-oligo cyCIF platform capable of generating high dimensional images to characterize the spatial proteomics of the hallmarks of cancer.

When fishing bites: Understanding angler responses to shark depredation

Shark depredation, the full or partial removal of a hooked fish by a shark before it is landed, is anecdotally increasing in the United States. Perceptions of depredation by anglers and fishing guides may influence their behavior and have cascading effects on sharks and recreational fisheries. However, to date, these perceptions have not been broadly quantified. To better understand how anglers and guides respond to shark depredation in recreational fisheries, we used an online survey open to saltwater anglers in North America, distributed electronically via social media and online platforms. Of the 541 respondents, 77% had experienced depredation in nearshore and pelagic fisheries in the last five years, with depredation more commonly reported in the southeastern United States. Emotional responses to depredation were significantly different between anglers and guides, with the latter feeling more intense negative emotions. Behavioral changes in response to depredation, such as targeting and harvesting sharks, were driven largely by negative emotional responses and perceptions of sharks as threats to target species, while changes to protect target species varied with positive emotional responses and angler demographics. Guides were predominantly concerned about increased mortality to their target species and loss of trophy fish from the population. In fact, 87% of guides experienced depredation when fishing with clients and overwhelmingly reported that depredation has a negative effect on their livelihood. Overall, these results can be used to help inform strategies to reduce depredation while accounting for the values of stakeholder groups, particularly anglers and those advocating for shark conservation.

Degradation of selected pharmaceuticals detected in wastewater systems using an enzyme-mediator system and identification of resulting transformation products

Pharmaceuticals are often found in municipal wastewater due to human excretion and disposal of drugs into sewerage systems. Conventional wastewater treatment plants were not designed for pharmaceutical removal and, hence, pharmaceutical concentrations ranging from ng L−1 to μg L−1 are often detected in treated wastewater, with additional treatment required for full removal. This study has investigated the potential of Trametes versicolour laccase enzyme and 2,2'-azino-bis-(3-ethyl-benzthiazoline-6-sulphonic acid) diammonium salt (ABTS) mediator system to degrade sulfamethoxazole, trimethoprim, metronidazole and phenytoin. The best degradation was observed at pH 5 for both sulfamethoxazole (97% in 12 hours) and trimethoprim (44% in 168 hours), using an initial micropollutant concentration of 100 µM, an enzymatic activity between 110–115 U L−1, and an ABTS concentration of 200 µM. Phenytoin and metronidazole were not degraded. Deamination followed by hydroxylation led to the formation of the two major sulfamethoxazole transformation products (TPs), whilst hydroxylation and hydroxylation/demethylation mechanisms formed the majority of the trimethoprim TPs. The sulfamethoxazole and trimethoprim TPs observed from the laccase-ABTS system were similar to the TPs obtained from degradation processes such as advanced oxidation or photodegradation. The laccase-ABTS system shows promise for control of emerging contaminants containing electron donating groups (such as amines and methoxy groups) on aromatic rings in wastewater systems.

3D Printing in Alginic Acid Bath of In-Situ Crosslinked Collagen Composite Scaffolds.

Bone-tissue regeneration is a growing field, where nanostructured-bioactive materials are designed to replicate the natural properties of the target tissue, and then are processed with technologies such as 3D printing, into constructs that mimic its natural architecture. Type I bovine collagen formulations, containing functional nanoparticles (enriched with therapeutic ions or biomolecules) or nanohydroxyapatite, are considered highly promising, and can be printed using support baths. These baths ensure an accurate deposition of the material, nonetheless their full removal post-printing can be difficult, in addition to undesired reactions with the crosslinking agents often used to improve the final structural integrity of the scaffolds. Such issues lead to partial collapse of the printed constructs and loss of geometrical definition. To overcome these limitations, this work presents a new alternative approach, which consists of adding a suitable concentration of crosslinking agent to the printing formulations to promote the in-situ crosslinking of the constructs prior to the removal of the support bath. To this aim, genipin, chosen as crosslinking agent, was added (0.1 wt.%) to collagen-based biomaterial inks (containing either 38 wt.% mesoporous bioactive glasses or 65 wt.% nanohydroxyapatite), to trigger the crosslinking of collagen and improve the stability of the 3D printed scaffolds in the post-processing step. Moreover, to support the material deposition, a 15 wt.% alginic acid solution was used as a bath, which proved to sustain the printed structures and was also easily removable, allowing for the stable processing of high-resolution geometries.

Retained intravascular catheter fragment at removal of implantable vascular access device: Incidence, risk factors, and outcomes

BackgroundRetained intravascular catheter fragments (RICF) are a rare complication of implantable vascular access device (IVAD) removal for which there is limited understanding of aetiology. There is a varied approach to management among the currently published literature. AimsThe aim of this study was to establish incidence, risk factors, and outcomes for RICF after attempted removal of IVADs. MethodsA single institution retrospective review was undertaken of individuals ≤ 25 years undergoing removal of IVADs from October 2014 to June 2019. Risk factors for RICF were explored using univariable logistic and Cox regression analysis. ResultsSix cases of RICF were identified among 654 line removal episodes (0.92% (95% CI 0.37–2%)) in patients aged 6–17 years (median 11, IQR 6–15 years). The main risk factor for RICF at removal was found to be line duration (OR 3.5/year, 95% CI 2.1–5.84, p < 0.0001). No RICFs occurred in lines indwelling for < 3 years. Five children with RICF ≤ 16 years were discussed with a paediatric cardiothoracic centre, and all were left in situ with 4 remaining asymptomatic. One had the fragment tip extruded through a wound, which required trimming. The other (17 years of age) developed an infected sinus for which partial removal with open excision followed by full removal with endovascular snare retrieval was performed by the adult vascular surgeons. ConclusionIVADs in-situ for longer than a three-year period are at greatest risk of RICF upon removal. Management with transfixion of line fragments to surrounding muscle seems prudent while invasive attempts at retrieval appear unwarranted.

Heat transfer evaluation of natural convection outside the condenser in Passive Residual Heat Removal System of Molten Salt Reactor

A full scale water-cooled Passive Residual Heat Removal System was designed and built for a 2 MW Molten Salt Reactor. In the process of heating the water tank, the heat transfer characteristics of the condenser in the system had an important impact on the temperature distribution and the development of thermal stratification in the water tank. Therefore, the heat transfer characteristics of the condenser at single-phase natural convection stage need to be experimentally researched and theoretically analyzed. Aiming at the condenser in the system, a series of experiments were carried out. Considering the influence of tube bundle effect on natural convection heat transfer, a set of theories using hydraulic diameter as characteristic length were put forward and applied to analyze the experimental results, which indicated the good agreement with the previous correlations consequently. This study can provide theoretical feasibility and experimental reference for the design of commercial molten salt reactor system in the future.

Reactive, Sparingly Soluble Calcined Magnesia, Tailor-Made as the Reactive Material for Heavy Metal Removal from Contaminated Groundwater Using Permeable Reactive Barrier

A laboratory method was designed and verified that allows for the testing of alkaline, magnesite-based reactive materials for permeable reactive barriers (PRBs) to remove heavy metals from contaminated groundwater. It was found that caustic calcined magnesia (CCM) with high reactivity and low solubility to remove Cu2+, Zn2+, Ni2+, and Mn2+ cations from mixed aqueous solutions can be prepared by calcination at a suitable temperature and residence time. Regarding the solubility of both the reactive material itself and the precipitates formed, the CCM should contain just a limited content of lime. One way is the calcination of a ferroan magnesite at temperatures above 1000 °C. However, the decrease in pH is accompanied by lower efficiency, attributed to the solid-phase reactions of free lime. A different way is the calcination of magnesite under the conditions when CaCO3 is not thermally decomposed. The virtually complete removal of the heavy metals from the model solution was achieved using the CCM characterised by the fraction of carbonates decomposed of approximately 80% and with the highest specific surface area. CCM calcined at higher temperatures could also be used, but this would be associated with higher consumption of crude magnesite. Under the conditions considered in the present work, the product obtained by the calcination at 750 °C for 3 h appeared to be optimal. The full heavy metal removal was observed in this case using less magnesite, and, moreover, at a lower temperature (resulting, therefore, in a lower consumption of energy for the calcination and material handling).

Estimation of countrywide N2O emissions from wastewater treatment in Switzerland using long-term monitoring data

Nitrous oxides (N2O) emissions contribute to climate change and stratospheric ozone depletion. Wastewater treatment is an important, yet likely underestimated, source of N2O emissions, as recent, long-term monitoring campaigns have demonstrated. However, the available data are insufficient to representatively estimate countrywide emission due to the brevity of most monitoring campaigns. This study showed that the emission estimates can be significantly improved using an advanced approach based on multiple continuous, long-term monitoring campaigns. In monitoring studies on 14 full-scale wastewater treatment plants (WWTPs), we found a strong variability in the yearly emission factors (EFs) (0.1 to 8% of the incoming nitrogen load) which exhibited a good correlation with effluent nitrite. But countrywide data on nitrite effluent concentrations is very limited and unavailable for emission estimation in many countries. Hence, we propose a countrywide emission factor calculated from the weighted EFs of three WWTP categories (carbon removal, EF: 0.1–8%, nitrification only: 1.8%, and full nitrogen removal: 0.9%). However, EF of carbon removal WWTPs are still highly uncertain given the expected variability in performance.The newly developed approach allows representative, country-specific estimations of the N2O emissions from WWTP. Applied to Switzerland, the estimations result in an average EF of 0.9 to 3.6% and total emissions of 410 to 1690 tN2O-N/year, which corresponds to 0.3–1.4% of the total greenhouse gas emissions in Switzerland. Our results demonstrate that better data availability and an improved understanding of long-term monitoring campaigns is crucial to improve current emission estimations. Finally, our results confirm several measures to mitigate N2O emissions from wastewater treatment; year-round denitrification, limiting nitrite accumulation, and stringent control of sludge age in carbon removal plants.

Awareness and Management of Breast Cancer in Women

Women have faced many challenges such as higher risk of breast cancer due to lack of awareness.The formation of hard mass or lump is a common sign. There are 4 stages of the breast cancer, and it is divided into two types, invasive and non-invasive. The common type is invasive ductal carcinoma which spread easily and also occur in men. The stage 3 cancer is known to be Inflammatory breast cancer and it can appear as metastatic cancer. Some risk factors can be controlled like breastfeeding can reduce chances of cancer. Different alternate options are selected for the treatment like full removal of breast or lump by the mastectomy or lumpectomy respectively. To destroy remaining cancerous cells, radiations are given, and chemotherapy reduces the size of tumor cell. In advance methods, gene therapy or immune system modulation is done to get rid of cancer.

Fish Assemblages Associated With Oil and Gas Platforms in the Gulf of Thailand

Decommissioning of offshore oil and gas structures is either occurring, or imminent in most regions of the world. Most jurisdictions require that offshore structures be removed for onshore disposal. However, there is growing interest in understanding the ecological and socio-economic benefits of leaving structures in the water. Descriptions of how fish utilize the vertical structure created by wellhead platform jackets (platforms) will provide insights into possible outcomes of decommissioning alternatives, such as full removal, leave in situ, or translocation to a designated reefing site. We surveyed fish assemblages associated with seven platforms and five reference sites located ∼150 km offshore in the central Gulf of Thailand. The platforms spanned the entire water column (∼75 m) and were a mix of three and four legged structures. We used a Remotely Operated Vehicle (ROV) fitted with an underwater stereo video system to quantify the abundance, size, biomass, and economic value of fish associated with the platforms. We recorded 43 species of fish on the platforms and five reference sites with most fishes on platforms categorized as coral-reef or coral-reef-associated species. We observed a strong vertical zonation in the fish assemblage on the platforms. The Regal demoiselle (Neopomacentrus cyanomos) was numerically dominant (75% of all fish observed). We measured 3,933 kg of fish on the platforms with Caranx sexfasciatus accounting for 76.12% of that. We conservatively estimate each platform had a scaled mean biomass of ∼2,927 kg and the fished species had scaled mean economic value of 175,500 Thai Baht per platform. We estimated that the biomass of fish associated with the seven platforms was at least four times higher per unit area than some of the world’s most productive coral reefs.

Break-even Analysis of Respirable Crystalline Silica (RCS) Exposure Interventions in the Construction Sector.

We investigated long-term economic impacts of respirable crystalline silica (RCS) removal interventions in the construction at the societal level. We estimated costs and benefits of two RCS exposure interventions, use of "respirators" and "wet method," over a 30-year time period. We identified economic impacts of the interventions under four different scenarios. Under current practices, we estimated that approximately 125 lung cancer cases attributable to RCS exposure would arise in 2060. Under the full exposure removal scenario, we estimated there would be 53 new cases. Over the 30-year time period, the estimated cumulative averted cases are 787 and 482 for respirators and wet method, respectively, which amount to net benefits of $422.13 and $394.92 million. Findings provide important information for policymakers seeking to reduce the economic burden of occupational lung cancer in society.

Laser-driven shocks to explore the effects of aging on the adhesion of silver sintered on copper substrate

The adhesion of thin silver joints sintered on metallic substrates is a major issue for their potential use in power electronics modules. Here, we explore how laser shock-induced spallation can provide a way to study this adhesion. Due to wave interactions inside the shock-loaded assembly, dynamic tensile stresses are induced near the copper-silver interface, resulting in partial or full removal of the silver layer. In order to investigate the effects of aging on the interface strength, experiments are performed on both as-sintered and aged samples. Time-resolved measurements of the free surface velocity provide information on wave dynamics and interface failure, but finite-element simulations show that inferring a quantitative value of the bonding strength from these data is still challenging. Nevertheless, post-recovery observations provide original insight into the debonding process, including some complex effects of aging, consistent with trends reported in the literature.

Denitrification Process Enhancement and Diversity of the Denitrifying Community in the Full Scale Activated Sludge System after Adaptation to Fusel Oil

Implementation of anaerobic digestion of primary sludge in modern wastewater treatment plants (WWTPs) limits the availability of organic carbon for denitrification in conventional nitrification-denitrification (N/DN) systems. In order to ensure efficient denitrification, dosage of the external carbon source is commonly undertaken. However, application of commercial products, such us ethanol or acetate, greatly increases operational costs. As such, inexpensive and efficient alternative carbon sources are strongly desirable. In this study, the use of the fusel oil, a by-product from the distillery industry, was validated in terms of the denitrification process enhancement and impact on the activated sludge bacterial community structure. The experiment was conducted at a full scale biological nutrient removal facility (210,000 PE), in the set of the two technological lines: the experimental line (where fusel oil was introduced at 45 cm3/m3 dose) and the reference line (without an external carbon source addition). During the experimental period of 98 days, conventional nitrate utilization rate (NUR) measurements were carried out on a regular basis in order to assess the biomass adaptation to the fusel oil addition and denitrification process enhancement. While the NURs remained at a stable level in the reference line (1.4 ± 0.1 mg NO3-N/g VSS·h) throughout the entire duration of the experiment, the addition of fusel oil gradually enhanced the denitrification process rate up to 2.7 mg NO3-N/g VSS·h. Moreover, fusel oil contributed to the mitigation of the variability of NO3-N concentrations in the effluent from the anoxic zone. The bacterial community structure, characterized by 16S rRNA PCR—DGGE and the clone libraries of the genes involved in the denitrification process (nirS and nirK), was comparable between the reference and the experimental line during the entire experimental period. In both analyzed lines, the most frequent occurrence of denitrifiers belonging to the genera Acidovorax, Alcaligenes, Azoarcus, Paracoccus and Thauera was noticed. Our results proved that fusel oil would a valuable substrate for denitrification. The addition of fusel oil enhances the process rate and does not reflect a severe selection pressure on the bacterial community at applicable doses. Practical application of fusel oil generates opportunities for the WWTPs to meet effluent standards and reduce operational costs, as well as optimizing waste management for the distillery industry.

Identifying the causes of residual stress in polycrystalline diamond compact (PDC) cutters by X-Ray diffraction technique

An attempt was made to identify the sources of residual stress in polycrystalline diamond compact (PDC) cutters by X-ray diffraction (XRD) technique. PDC retains residual stress after sintering and this residual stress plays an important role for cutter performance. X-ray diffraction method of residual stress measurement is very common because it is nondestructive. Residual stress was measured in a finished 16 mm PDC cutter and changes in residual stress were observed as the substrate was removed by grinding. Residual stress was also measured after full removal of cobalt from the diamond table by leaching. Comparison was made between the as-pressed PDC cutter, after removing the substrate, and after removing the cobalt to understand the relative contribution of geometry and cobalt binder to overall residual stress. An additional measurement was made under High Pressure High Temperature (HPHT) compacted diamond powder in the absence of cobalt to evaluate the contribution of high temperature deformation of diamond particle on residual stress.

Method to improve the surface shape of BK7 glass in full-aperture polishing.

Full aperture polishing is a significant process to fabricate optical workpieces with nano figure precision. It has the characteristics of excellent full spectrum uniform removal ability, fast convergence speed, high machining accuracy, and low production cost, which makes it the first choice for the processing of large-aperture optical elements. However, with BK7 glass it is difficult to achieve deterministic processing due to its large thermal expansion coefficient and other factors, and the surface shape accuracy is difficult to improve. In this paper, the thermal deformation of BK7 glass is analyzed first, and then the temperature distribution in the element is measured during full-aperture polishing. The influence of the temperature field in the optics on the accuracy of the final surface shape is analyzed, and the quantitative relationship between the temperature difference and the surface shape is established. In addition, the methods of deterministically controlling the surface shape of optics such as polishing liquid temperature control and immersion polishing are proposed. Finally, the model of quantitative control of the surface shape of optics is verified by experiments, which improve the surface shape accuracy of 600 mm BK7 optics to 0.2λ.