Full Content Research Articles

The Role of Islam in Alleviating Poverty: An Analytical Study

Poverty is an undesirable social phenomenon whose existence and expansion in society lead to all-around miserable consequences in the short and long term. This ominous phenomenon is condemned in all human religions and cultures, and various ways and methods have been proposed to eradicate it from society. Islam considers a life with prosperity and peace as the natural right of human beings and confronts the obstacles to the realization of this goal. Therefore, it gives teachings to its followers that, by following them, they will enjoy a life of full joy and contention, and their physical and mental health will be guaranteed. Undoubtedly, poverty is one of the biggest concerns of all human societies and economic systems. Poverty is one of the negative phenomena that pose a threat to life. Economic schools of thought have presented different ways to deal with it, but so far, they have not yet succeeded in eliminating poverty from human lives. Its occurrence is called an unpleasant complication. Poverty is one of the most important long-standing issues in developed and developing countries, including Islamic countries. To solve the problem of poverty, many studies have studied the factors affecting poverty. The purpose of this research is to identify the role of Islam in reducing poverty. In the question of the research, it is stated that what is the role of Islam in reducing poverty, and what are its recommendations for reducing poverty? The research method in this study is descriptive-analytical, and the required information was collected from library sources and a combination of the Delphi method.

A Semantically Rich ‘Do’‐Support Verb in the Camuno Dialect of Northern Italy

AbstractIn the Camuno dialect of northern Italy, ‘do’‐support may be used to form the interrogative. In some varieties, this is optional, and it co‐exists with the alternative interrogative method of using the main verb alone. Through an elicitation experiment, participants produced their preferred version of a question based on a certain main verb with given context. The likelihood that ‘do’‐support was used varied according to the supported verb's semantics and the context pragmatics, specifically: (a) the degree to which the verb denotes activity (directly or indirectly); and (b) the role of the subject as an effector, or ‘do’‐er of that activity. Unlike for ‘do’‐support in English, a purely syntactic function does not seem relevant for Camuno ‘do’. The study shows that: (1) even if, syntactically, the support verb resembles an auxiliary, it may have full lexical content; and (2) that there exists a credible grammaticalisation pathway from a lexical ‘do’ verb to a semantically bleached, contentless ‘do’, seemingly motivated by a social preference for the ‘do’‐support construction and a desire to simplify the interrogative system.

TRALI and TACO syndrome. Pathophysiology, diagnosis and treatment: a review

INTRODUCTION: TRALI (transfusion-related acute lung injury) and TACO (transfusion-associated circulatory overload) are severe post-transfusion reactions with high hospital mortality, uncertainty in pathophysiologic mechanisms and a blurred clinical presentation often lead to these conditions being underdiagnosed or missed by clinicians. OBJECTIVE: To analyze and summarize the current understanding of the pathophysiology, differential diagnosis and treatment of TRALI and TACO syndrome. To highlight the best approaches and current practices to improve treatment efficacy and awareness among specialists. MATERIALS AND METHODS: Articles in the following databases were analyzed: PubMed, eLibrary. The main inclusion criteria were: free access to the full content of the publications, compliance with the review topics concerning pathophysiology, diagnosis and treatment of TRALI- and TACO-syndrome. Exclusion criteria: abstracts, conference proceedings and editorial letters, as well as publications not indexed in specialized abstract databases. RESULTS: This article presents the main reference points, thanks to which clinicians can make a differential diagnosis among posttransfusion complications and select the optimal treatment. Since TACO is a simulated cardiogenic pulmonary edema as a result of altered cytokine profile, and TRALI-syndrome is a consequence of specific immunologic conflict between donor and recipient after hemotransfusion, these conditions should be differentiated in the inpatient setting, and specialists should use the full range of modern laboratory and instrumental methods. CONCLUSIONS: Despite a large number of studies, the pathophysiologic mechanisms of TRALI and TACO remain somewhat unclear, and current approaches to diagnosis and treatment are not effective. Therefore, the existing gaps in the diagnostics of posttransfusion reactions should be clarified in further studies, and clinicians should be extra vigilant in their choice of diagnosis.

Overuse of computed tomography for mild head injury: A systematic review and meta-analysis.

Computed tomography (CT) scan is a common imaging technique used to evaluate the severity of a head injury. The overuse of diagnostic interventions in the health system is a growing concern worldwide. Objectives: The aim of this systematic review is to investigate the rate of CT scan overuse in cases of mild head injury. Eligibility criteria: We encompassed observational studies-either designed as cohort, case-control, or cross-sectional investigations-that reported on CT scan overuse rates for mild head injuries. Studies had to be published in peer-reviewed, English-language sources and provide full content access Information sources: Web of Sciences, Scopus, Medline via PubMed, the Cochrane Library and Embase were searched from inception until April 1, 2023. Studies were included if reporting the overuse of CT scans for mild head injuries using validated criteria. Risk of bias: We used the Risk Of Bias In Non-randomised Studies - of Interventions (ROBINS-I) tool to evaluate the risk bias assessment of included studies. Two independent reviewers evaluated the eligibility of studies, extracted data, and assessed study quality by using the Newcastle-Ottawa Scale. Synthesis of results: Overuse estimates were calculated using a random-effects model. Subgroup analyses were performed to investigate any sources of heterogeneity. Point rate of overuse of CT scans for mild head injuries was the main outcome measured as percentage point estimates with corresponding 95% CIs. Included studies: Of the 913 potentially relevant studies identified, eight studies were selected for the final analysis. Synthesis of results: The pooled rate of CT scan overuse in patients with mild head injury was found to be 27% [95% CI: 16-43; I2 = 99%]. The rate of CT scan overuse in mild head injury cases varied depending on the criteria used. The rate of CT scan overuse was 37% [95% CI: 32-42; I2 = 0%] with the Glasgow Coma Scale (GCS), 30% [95% CI: 16-49; I2 = 99%] with the Canadian computed tomography head rule, and 10% [95% CI: 8-14; I2 = 0%] with the Pediatric Emergency Care Applied Research Network criterion (PERCAN). Based on subgroup analyses, the rate of CT scan overuse in mild head injury cases was observed to be 30% with the Canadian computed tomography head rule criterion, 43% with the National Institute for Health and Clinical Excellence criterion, and 18% with the New Orleans criterion. Limitations of evidence: The restricted number of included studies may impact generalizability. High heterogeneity was observed, leading to subgroup analyses based on age, assessment criteria, and study region. Absent data on overuse causes hinders drawing conclusions on contributing factors. Furthermore, this study solely addressed overuse rates, not associated harm or benefits. Interpretation: The overuse of CT scans in mild head injury patients is concerning, as it can result in unnecessary radiation exposure and higher healthcare costs. Clinicians and policymakers should prioritize the implementation of guidelines to reduce unnecessary radiation exposure, healthcare costs, and potential harm to patients. The study protocol of this review was registered in PROSPERO under the identification code CRD42023416080. https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023416080.

Exploring the application of PLS-SEM in construction management research: a bibliometric and meta-analysis approach

PurposeThe partial least squares structural equation modeling (PLS-SEM) approach for construction management (CM) scholars has become the preferred approach for its capability of assessing the complex relationship and relaxed normality and sample size assumptions. This paper systematically maps the structure of knowledge about PLS-SEM in CM using bibliometric analysis. Also, the study employs meta-analysis to explore how data and model characteristics, model evaluation and advanced modeling techniques have been utilized in the CM domain.Design/methodology/approachThis study integrated two methods: bibliometric analysis on a sample of 211 articles identified using the PRISMA framework and meta-analysis on 163 articles identified based on the availability of full-length articles and relevant information.FindingsThe results revealed the leading knowledge formation entities (countries, institutions, authors, sources and documents). Also, the study employs full content analysis to identify six research themes, and meta-analysis is used to explore the use of PLS-SEM based on the following criteria: (1) reasons for using PLS-SEM in CM, (2) data characteristics, (3) model characteristics and evaluation and (4) use of advanced modeling and analysis techniques. Further, the study uses regression analysis and identifies “advanced modeling and analysis techniques” as the critical feature responsible for the publication in a journal with high scientific prestige. Finally, the study presented the comprehensive guidelines to be used by construction management scholars who wish to use PLS-SEM in their research work.Originality/valueTo the author’s knowledge, it is the first study of this kind to use PLS-SEM in CM research. This study provides an extensive analysis of the Scopus database and an in-depth review of the data characteristics, model characteristics and use of advanced modeling techniques in CM research.

КӨРКӨМ КОТОРМОНУН ӨЗ АРА БӨЛҮНҮШТӨРҮ ЖАНА АЛАРДЫН СПЕЦИФИКАЛЫК ӨЗГӨЧӨЛҮКТӨРҮ

The article states that grammatical forms, syntactic constructions, sentence symmetry, syntactic figures, rhythmicity of poetic and prose speech, repetitions, parallelisms, etc. in the text have their own national and cultural specifics. Due to the absence or underdevelopment of fundamental works on translation studies, translation criticism, translation history and translation theory in the native language in the native language, we are not able to select and present to the general reader the best translations that clarify the qualitative characteristics, specific features and mutual differences of a true literary translation. Literary translation requires the highest level of equivalence, which can only be achieved by a creative, diligent, experienced translator, overflowing with translation skills. Indeed, in the history of literature there are poets and writers who became famous for their free translation. One of the main tasks of the translator is to provide the full content of the original, where the content of the original and the translation is identical, compatible and the correct translation is very important. Equivalence is the component that fulfills and implements this unity.

VOLUME 26, FULL CONTENTS

VOLUME 26, FULL CONTENTS

Virtual monitors vs. physical monitors: an empirical comparison for productivity work

Virtual monitors can display information through a head-worn display when a physical monitor is unavailable or provides insufficient space. Low resolution and restricted field of view are common issues of these displays. Such issues reduce readability and peripheral vision, leading to increased head movement when we increase the display size. This work evaluates the performance and user experience of a virtual monitor setup that combines software designed to minimize graphical transformations and a high-resolution virtual reality head-worn display. Participants performed productivity work across three approaches: Workstation, which is often used at office locations and consists of three side-by-side physical monitors; Laptop, which is often used in mobile locations and consists of a single physical monitor expanded with multiple desktops; and Virtual, our prototype with three side-by-side virtual monitors. Results show that participants deemed Virtual faster, easier to use, and more intuitive than Laptop, evidencing the advantages of head and eye glances over full content switches. They also confirm the existence of a gap between Workstation and Virtual, as Workstation achieved the highest user experience. We conclude with design guidelines obtained from the lessons learned in this study.

DOES THE SMALL PRINT REALLY MATTER? THE INFLUENCE OF EXPLICIT EXPOSURE TO DISCLAIMERS ON THE PERCEPTION OF TV COMMERCIALS

Disclaimers, which should prevent advertising audience from being falsely informed, are usually ignored by viewers. The present study demonstrates that when the viewers are exposed to the full content of commercials, including the small print disclaimers, their evaluation of the products and producers is, contrary to expectations, higher. However, the viewers fail to notice the manipulative discursive tactics applied by the advertisers, involving strategic use of disclaimers. This suggests that disclaimers do not perform their protective role effectively.

Sharp bounds in the latent index selection model

A fundamental question underlying the literature on partial identification is: what can we learn about parameters that are relevant for policy but not necessarily point-identified by the exogenous variation we observe? This paper provides an answer in terms of sharp, analytic characterizations and bounds for an important class of policy-relevant treatment effects, consisting of marginal treatment effects and linear functionals thereof, in the latent index selection model as formalized in Vytlacil (2002). The sharp bounds use the full content of identified marginal distributions, and analytic derivations rely on the theory of stochastic orders. The proposed methods also make it possible to sharply incorporate new auxiliary assumptions on distributions into the latent index selection framework. Empirically, I apply the methods to study the effects of Medicaid on emergency room utilization in the Oregon Health Insurance Experiment, showing that the predictions from extrapolations based on a distribution assumption (rank similarity) differ substantively and consistently from existing extrapolations based on a parametric mean assumption (linearity). This underscores the value of utilizing the model’s full empirical content in combination with auxiliary assumptions.

Multimode vibrational dynamics and orientational effects in fluorescence-encoded infrared spectroscopy. I. Response function theory.

Fluorescence-encoded infrared (FEIR) spectroscopy is an emerging technique for performing vibrational spectroscopy in solution with detection sensitivity down to single molecules. FEIR experiments use ultrashort pulses to excite a fluorescent molecule's vibrational and electronic transitions in a sequential, time-resolved manner, and are therefore sensitive to intervening vibrational dynamics on the ground state, vibronic coupling, and the relative orientation of vibrational and electronic transition dipole moments. This series of papers presents a theoretical treatment of FEIR spectroscopy that describes these phenomena and examines their manifestation in experimental data. This first paper develops a nonlinear response function description of Fourier-transform FEIR experiments for a two-level electronic system coupled to multiple vibrations, which is then applied to interpret experimental measurements in the second paper [L. Whaley-Mayda et al., J. Chem. Phys. 159, 194202 (2023)]. Vibrational coherence between pairs of modes produce oscillatory features that interfere with the vibrations' population response in a manner dependent on the relative signs of their respective Franck-Condon wavefunction overlaps, leading to time-dependent distortions in FEIR spectra. The orientational response of population and coherence contributions are analyzed and the ability of polarization-dependent experiments to extract relative transition dipole angles is discussed. Overall, this work presents a framework for understanding the full spectroscopic information content of FEIR measurements to aid data interpretation and inform optimal experimental design.

The Awareness Of Implementing Building Information Modelling (Bim) For Educators In Malaysia Tvet Institutions: A Systematic Literature Review

BIM technology has become trending in the Malaysian construction industry recently; numerous research studies identify the lack of professional skills in BIM application as a primary reason for adopting BIM in industries. Facing professional skill issues, BIM education is related to cooperation with the industry, universities, technical colleges, and communities by practicing and specialising in training. This requires studying specific issues in BIM implementation among educators in TVET institutions, and coordination with industry professionals is necessary to unveil the present status of BIM in each of the professions. The Malaysian TVET Institutions are responding to these barriers by implementing BIM to the institution with the curriculum design, collaboration extending to multiple professionals in the industries at the same time, and providing adequate education and training to their educators. With this objective, a systematic literature review was carried out on WOS and SCOPUS guided by the ROSES methodology. Inclusion and exclusion criteria were selected based on keywords, abstracts, and the full content of the articles. In the end, 14 articles were thoroughly studied, the integration and evaluation methods analysed, and results obtained. The analysis shows the empirical evidence to identify the awareness and determine the barriers to implementing BIM among educators in Malaysia TVET Institutions. Finally, recommended strategies for mitigating barriers to implementing BIM for educators were identified

MULTIMEDIA SUMMARIZATION USING SPACY

The main objective of this paper is to propose a summarizing system based on natural language processing to summarize the data that can be in either video, audio or textual format. Video summarization is to generate a short summary of the content of a video by selecting and presenting the most informative or interesting materials for potential users. With the arrival of high-speed Internet and low-cost storage, the amount of data has been generated at a rocket pace, most of it is in the form of visual or video data. This makes them an important information dispensing tool. Searching and analyzing such a large number of videos is an extremely tedious task Unlike images, where information may be gathered from a single frame, videos need the user to watch the full content, regardless of duration, which presents a challenge to information extraction. Similarly, we save time by extracting crucial information from audio recordings and text. The system focuses on the development of a module using Natural Language Processing with python to summarize the YouTube videos, audio files and textual data. KEYWORDS - Multimedia, Natural Language Processing, Spacy, Summarization, Tokenization

Influence of the gene pool of the breed on the content and variability of copper in the liver of pigs

The average level and variability of copper in the liver of pigs of different breeds were studied. Samples of parenchymal organs from pigs were taken immediately after slaughter and analysed at the analytical centre for collective use of V.S. Sobolev Institute of Geology and Mineralogy of the Siberian Branch of the Russian Academy of Sciences using the method of atomic absorption spectrometry with flame and electrothermal atomisation on the SOLAAR M6 spectrometer (USA) by GOST 26929-94 Raw materials and food products— sample preparation Mineralization to determine the content of toxic elements. A normal distribution of the trait was found only in the Landrace breed (W = 0.94). In pig breeding areas, the content of heavy metals in soil, water and feed was studied, which did not exceed the maximum permissible concentration. The most significant variability of the microelement was observed in the Kemerovo breed, the least - in the Landrace breed. The full copper content was marked in the early ripening meat breed and the minimum in the Landrace breed. A smaller interquartile range about the Kemerovo and early meat breeds characterised the level of copper in the liver of Landrace pigs.

Machine Learning to Predict Rice Stock for Food Security: A Brief Study

The present study aims at shedding light on machine learning in agriculture by thoroughly reviewing the recent scholarly literature based on keywords’ combinations of “machine learning” and “rice”. Only journal papers were considered eligible that were published within 2020 – 2023. Approximately 49 articles from scopus and google scholar database. It was selected for full content review after the pre-screening process. The results indicated that this topic pertains to different disciplines that favor convergence research at the international level. Prediction criteria related to food security were found to be the most inputs of prediction models. Machine learning models such as Random forest result in high accuracy in predict rice stock on 98%. This study will constitute a beneficial guide to all stakeholders towards enhancing awareness of the potential advantages of using machine learning in predict rice stock and contributing to a more systematic research on this topic.

The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors.

The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (https://www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes almost 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.16177. G protein-coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2023, and supersedes data presented in the 2021/22, 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.

The Concise Guide to PHARMACOLOGY 2023/24: Transporters.

The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (https://www.guidetopharmacology.org/), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes almost 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.16182. Transporters are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ion channels, nuclear hormone receptors, catalytic receptors and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2023, and supersedes data presented in the 2021/22, 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.

The Concise Guide to PHARMACOLOGY 2023/24: Catalytic receptors.

The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and nearly 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (https://www.guidetopharmacology.org/), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes almost 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.16180. Catalytic receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ion channels, nuclear hormone receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2023, and supersedes data presented in the 2021/22, 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.

The Concise Guide to PHARMACOLOGY 2023/24: Enzymes.

The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes almost 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.16176. In addition to this overview, in which are identified 'Other protein targets' which fall outside of the subsequent categorisation, there are six areas of focus: G protein-coupled receptors, ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2023, and supersedes data presented in the 2021/22, 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.

The Concise Guide to PHARMACOLOGY 2023/24: Introduction and Other Protein Targets.

The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes almost 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.16176. In addition to this overview, in which are identified 'Other protein targets' which fall outside of the subsequent categorisation, there are six areas of focus: G protein-coupled receptors, ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2023, and supersedes data presented in the 2021/22, 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.