Frontal Alpha Research Articles

Emotion Regulation Choice in Internet Addiction: Less Reappraisal, Lower Frontal Alpha Asymmetry.

Individuals with internet addiction (IA) show difficulties in emotion regulation. However, they could effectively employ emotion regulation strategies when instructed. We speculate that this discrepancy might be caused by maladaptive emotion regulation choices. Recent studies indicated that decreased activity of the left frontal cortex could be a neural marker of reappraisal use. To address this problem, individuals with IA (n = 17, IA group) and healthy individuals (n = 23, healthy control [HC] group) were required to choose an emotion regulation strategy between reappraisal and distraction to regulate their emotions varying in emotional intensity and valence. We also compared the resting state frontal alpha asymmetry (FAA) of these 2 groups. The results replicated more choices of reappraisal in low- versus high-intensity emotional contexts across groups. More importantly, the IA group chose reappraisal less frequently compared with the HC group, irrespective of emotional intensity. Furthermore, we found individuals with IA have lower FAA than healthy controls, and FAA shows a positive correlation with the use of reappraisal. These findings suggest that IA alters individuals' patterns of emotion regulation choice and impairs frontal activities, causing difficulties in emotion regulation.

Alpha desynchronization during Stroop test unmasks cognitively healthy individuals with abnormal CSF Amyloid/Tau

Synaptic dysfunctions precede cognitive decline in Alzheimer's disease by decades, affect executive functions, and can be detected by quantitative electroencephalography (qEEG). We used quantitative electroencephalography combined with Stroop testing to identify changes of inhibitory controls in cognitively healthy individuals with an abnormal versus normal ratio of cerebrospinal fluid (CSF) amyloid/total-tau. We studied two groups of participants (60–94 years) with either normal (CH-NAT or controls, n = 20) or abnormal (CH-PAT, n = 21) CSF amyloid/tau ratio. We compared: alpha event-related desynchronization (ERD), alpha spectral entropy (SE), and their relationships with estimated cognitive reserve. CH-PATs had more negative occipital alpha ERD, and higher frontal and occipital alpha SE during low load congruent trials, indicating hyperactivity. CH-PATs demonstrated fewer frontal SE changes with higher load, incongruent Stroop testing. Correlations of alpha ERD with estimated cognitive reserve were significant in CH-PATs but not in CH-NATs. These results suggested compensatory hyperactivity in CH-PATs compared to CH-NATs. We did not find differences in alpha ERD comparisons with individual CSF amyloid(A), p-tau(T), total-tau(N) biomarkers.

Oxytocin enhances neural approach towards social and non-social stimuli of high personal relevance

Oxytocin (OT) plays a pivotal role in a variety of complex social behaviors by modulating approach-avoidance motivational tendencies, but recently, its social specificity has been challenged. Here, a randomized, double-blind, placebo-controlled study was conducted with forty young adult men, investigating the effect of a single-dose of OT (24 IU) on behavioral and neural approach-avoidance. Frontal alpha asymmetry, indexing neurophysiological approach-avoidance, was obtained from electroencephalographic recordings while participants were presented with a series of pictures, individually rated in terms of personal relevance (i.e., high versus low positive/negative emotional evocativeness) and categorized as social or non-social. Additionally, participants could prolong (approach) or shorten (avoid) the viewing-time of each picture, providing a measure of behavioral approach-avoidance. Intranasal OT enhanced both behavioral and neural approach (increased viewing-time), particularly towards negatively valenced pictures of both social and non-social nature, thus challenging the notion that OT’s effects are specific to social stimuli. Neurally, OT specifically amplified approach-related motivational salience of stimuli that were self-rated to have high personal relevance, but irrespective of their social nature or rated affective valence (positive/negative). Together, these findings provide support to the General Approach-Avoidance Hypothesis of OT, suggesting a role of OT in amplifying the motivational salience of environmental stimuli with high (personal) relevance, but irrespective of their social/non-social nature.Clinical Trial Number: The study design was registered at ClinicalTrials.gov (NCT04443647; 23/06/2020; https://clinicaltrials.gov/ct2/show/NCT04443647).

Alpha oscillations predict paroxetine response to low sexual desire in depression

• Low sexual desire in depression has QEEG markers. • Greater frontal alpha power is related with libidinal unresponsiveness to paroxetine. • Impaired attention is also related with low sexual desire in depression. Decreased sexual desire (libido) is one of the most common sexual complaints in patients with depression. It is known that antidepressants have certain effects on sexual life. Paroxetine is one of those antidepressants. However, the sexual adverse effects of paroxetine are unpredictable. This retrospective study aimed at determining the electrophysiological markers of paroxetine treatment effect on sexual desire in patients with depression ( N = 56). Quantitative electroencephalography (QEEG) spectral power across all frequency bands were examined in depressed patients with decreased or normal sexual desire. Analysis of covariance was conducted on baseline qEEG, taking attention condition and severity of depression (Hamilton Depression Rating Scale -HDRS) as covariates. Patients whose sexual desire did not improve had higher frontal alpha power and impaired attention function at baseline examination. The results could be taken as preliminary due to the modest sample size. Based on the present findings, it can be concluded that frontal alpha power can be a biomarker of lack of libido improvement after treatment with paroxetine.

Context matters: Cortical rhythms in infants across baseline and play

This study uses electroencephalography (EEG) to examine infants’ cortical activity during baseline while they watched a dynamic audiovisual display and while engaged in play with an object and parent. Fifty-five 6- to 12-month-old infants participated in both baseline and play with their mother. We hypothesized that the baseline task recruits relatively more exogenous attention due to the dynamic audiovisual task, while the play task recruits relatively more endogenous attention when exploring the toy. We expected higher frontal theta and alpha power during play, reflecting higher endogenous control of attention compared to the baseline task. We expected the faster rhythms, beta and gamma, to have higher power during baseline at frontal locations, reflecting the salient attention-grabbing (exogenous) attributes of the baseline task in comparison to play. We also examined changes in parietal power between contexts. Our results were consistent with the expectations. Theta (3–6 Hz) and alpha (6–9 Hz) power were higher at frontal sites (Fp1/Fp2) during play relative to baseline. Beta (9–30 Hz) and gamma (30–50 Hz) power were higher at frontal (Fp1/Fp2) and frontal medial sites (F3/F4) during baseline relative to play. Alpha power was higher during baseline at frontal medial sites (F3/F4) relative to play. Beta and gamma power was higher during play at parietal sites (P3/P4). The results are discussed in terms of the potential role of different cortical rhythms over the scalp as they respond to relative endogenous and exogenous attentional demands.

Behavioural effects of task-relevant neuromodulation by rTMS on giving-up

Recent studies suggest that online repetitive transcranial magnetic stimulation (rTMS) can induce local entrainment of ongoing endogenous oscillatory activity during a task. This effect may impact cognitive performance, depending on the function of the oscillation. In this study, we aimed to investigate the effects of stimulation frequency and target location that are relevant to the cognitive processes of giving-up. We first investigated the correlations between the EEG oscillations and cognitive giving-up processes during problem-solving tasks (Experiment 1). We then conducted online rTMS to examine the frequency-dependent stimulation effects of rTMS on the performance of problem-solving tasks and ongoing oscillations (Experiment 2). The results of Experiment 1 suggested that the frontal theta rhythm is associated with the giving-up processes and that the frontal alpha rhythm is associated with problem-solving behaviour. Accordingly, we hypothesised that rTMS at the theta frequency would induce ongoing theta activity and accelerate the giving-up behaviour, while rTMS at the alpha frequency would induce ongoing alpha activity and slow down the giving-up behaviour in Experiment 2. The results showed that theta-frequency rTMS application induced an increase in theta amplitudes and shortened the giving-up response. Alpha-frequency rTMS application induced an increase in alpha amplitudes, but did not change giving-up responses. Considering the close resemblance between giving-up behaviour and rumination in depression, neuromodulation of cognitive giving-up processes may lead to a new intervention to treat depression by rTMS. Furthermore, this study strengthens the hypothesis that modulating task-relevant oscillations by rTMS could induce behavioural changes related to cognitive performance.

Effects of the calorie content of visual food stimuli and simulated situations on event-related frontal alpha asymmetry and event-related potentials in the context of food choices

Approach and avoidance tendencies play an important role in everyday food choices when choosing between high-caloric, rather unhealthy, and low-caloric, rather healthy options. On a neuronal level, approach and avoidance motivation have been associated with asymmetrical activity of the frontal cortex, often quantified by alpha power averaged over several seconds of resting electroencephalogram (EEG). Going beyond the analysis of resting EEG, the present study aimed to investigate asymmetrical frontal activity in direct response to food stimuli in an event-related design and in combination with event-related potentials (ERPs). Therefore, a sample of 56 young and healthy participants completed a food choice task. They were asked to choose from a selection of high-caloric and low-caloric foods which they would want to eat on a normal day (baseline), when being on a diet, and in a reward situation. On the behavioural level, there was a clear preference for low-caloric foods. Well in line with that, time-frequency analyses of alpha asymmetry revealed relatively stronger temporary (950–1175 ms) left-hemispheric frontal activity, that is, a stronger approach tendency, in response to low-caloric as compared to high-caloric foods. Furthermore, larger P300 for low-caloric foods indicated an increased task relevance of low-caloric foods in the baseline and the reward situation. In contrast, the late positive potential (LPP), an index of subjective value, was larger for high-as compared to low-caloric foods, reflecting the intrinsic rewarding properties of high-caloric foods. ERPs, but not frontal alpha asymmetry, were influenced by the situational context.

Brain fragility among middle-aged and elderly patients from electroencephalogram during induction of anaesthesia.

Brain fragility among middle-aged and elderly patients from electroencephalogram during induction of anaesthesia.

DUPLICATE: Electroacupuncture plus moxibustion for major depressive disorder: A randomized, sham-controlled, pilot clinical trial

BackgroundThe first treatment option for major depressive disorder (MDD) is antidepressants, however, there is substantial demand for alternative therapies due to its low compliance and remission rates. This study was aimed to explore the effectiveness, safety, and feasibility of electroacupuncture plus moxibustion therapy for MDD.MethodsThirty adults with MDD were randomly assigned to the treatment group (TG) or control group (CG). The TG was treated with electroacupuncture plus moxibustion, and the CG received sham interventions at non-acupoints for 8 weeks. The primary outcome measure was the intergroup difference of the mean change of total score of the Hamilton rating scale for depression (HRSD) between baseline and week 9. Secondary outcome measures were Beck's depression inventory, insomnia severity index, the state-trait anxiety inventory, the EuroQol-5 dimension index, the measure yourself medical outcome profile version 2, and frontal alpha asymmetry measured by electroencephalography. Adverse events (AEs) were monitored for safety assessment.ResultsThe primary outcome measure was not significantly different between the two groups (p=0.2641), although the scores of HRSD in both groups improved significantly after treatment. No significant difference was identified between groups in secondary outcome measures. The incidence of AE was not significantly different between the two groups (p=0.1067).ConclusionA clinical trial using electroacupuncture plus moxibustion for MDD seems feasible. However, further studies with the larger size, adopting ideal controls are warranted to provide a confirmative conclusion to the efficacy and safety of electroacupuncture plus moxibustion for MDD.Trial registrationThe protocol was registered at Korean Clinical Trial Registry (CRIS-KCT0001810)

Predictive Feedback, Early Sensory Representations, and Fast Responses to Predicted Stimuli Depend on NMDA Receptors.

Learned associations between stimuli allow us to model the world and make predictions, crucial for efficient behavior (e.g., hearing a siren, we expect to see an ambulance and quickly make way). While there are theoretical and computational frameworks for prediction, the circuit and receptor-level mechanisms are unclear. Using high-density EEG, Bayesian modeling, and machine learning, we show that inferred "causal" relationships between stimuli and frontal alpha activity account for reaction times (a proxy for predictions) on a trial-by-trial basis in an audiovisual delayed match-to-sample task which elicited predictions. Predictive β feedback activated sensory representations in advance of predicted stimuli. Low-dose ketamine, an NMDAR blocker, but not the control drug dexmedetomidine, perturbed behavioral indices of predictions, their representation in higher-order cortex, feedback to posterior cortex, and pre-activation of sensory templates in higher-order sensory cortex. This study suggests that predictions depend on alpha activity in higher-order cortex, β feedback, and NMDARs, and ketamine blocks access to learned predictive information.SIGNIFICANCE STATEMENT We learn the statistical regularities around us, creating associations between sensory stimuli. These associations can be exploited by generating predictions, which enable fast and efficient behavior. When predictions are perturbed, it can negatively influence perception and even contribute to psychiatric disorders, such as schizophrenia. Here we show that the frontal lobe generates predictions and sends them to posterior brain areas, to activate representations of predicted sensory stimuli before their appearance. Oscillations in neural activity (α and β waves) are vital for these predictive mechanisms. The drug ketamine blocks predictions and the underlying mechanisms. This suggests that the generation of predictions in the frontal lobe, and the feedback pre-activating sensory representations in advance of stimuli, depend on NMDARs.

Mirroring and brain connectivity of gesture observation

Non-verbal communication involves di rent channels, as gestures, to communicate different information. The present study aims investigating the electrophysiological (EEG) correlates underlying the use of affective, social, and informative gestures during gesture observation by an encoder (who observed to reproduce the gestures successively) and decoder (who simply observed the gestures). Mirroring mechanisms were considered for a gesture observation task. Results showed an increase of frontal alpha, delta, and theta brain responsiveness and intra-brain connectivity for affective and social gestures. and of posterior (temporo-parietal) alpha activity and alpha and delta intra-brain connectivity for informative ones. Concerning inter-agents' role, similar responses were found for all gestures. Regarding gesture valence, an increase of delta and theta activity was observed for positive gestures on the left cerebral side. This study, therefore, revealed the function of gestures' type and valence in influencing individuals' brain activity, showing the presence of mirroring mechanisms underlying gesture observation.

Frontal and parietal EEG alpha asymmetry: a large-scale investigation of short-term reliability on distinct EEG systems

EEG resting-state alpha asymmetry is one of the most widely investigated forms of functional hemispheric asymmetries in both basic and clinical neuroscience. However, studies yield inconsistent results. One crucial prerequisite to obtain reproducible results is the reliability of the index of interest. There is a body of research suggesting a moderate-to-good reliability of EEG resting-state alpha asymmetry, but unfortunately sample sizes in these studies are typically small. This study presents the first large-scale short-term reliability study of frontal and parietal EEG resting-state alpha asymmetry. We used the Dortmund Vital Study data set containing 370 participants. In each participant, EEG resting state was recorded eight times, twice with their eyes opened, twice with their eyes-closed, each on two different EEG systems. We found good reliability of EEG alpha power and alpha asymmetry on both systems for electrode pairs. We also found that alpha power asymmetry reliability is higher in the eyes-closed condition than in the eyes-open condition. The frontomedial electrode pair showed weaker reliability than the frontolateral and parietal electrode pairs. Interestingly, we found no population-level alpha asymmetry in frontal electrodes, one of the most investigated electrode sites in alpha asymmetry research. In conclusion, our results suggest that while EEG alpha asymmetry is an overall reliable measure, frontal alpha asymmetry should be assessed using multiple electrode pairs.

How Neuroscience-Based Research Methodologies Can Deliver New Insights to Marketers

While traditional market research methods are focused on surveys and group discussions, consumers’ attitudes, the choices they make, and the behaviour they display are all driven by a complex set of factors, and much of what is happening takes place in the subconscious mind. Learning that a stimulus engages in a positive way and that memory formation is taking place does not tell the marketer anything about the quality and impact of these memories or the engagement. With the technological advances, the emergence of neuroscience-based methodologies offers a higher degree of reliability. In the recent years, a noticeable increase in the use of eye-tracking and EEG frontal asymmetry technique was observed to measure cognitive processes of consumers among which are attention and perception to gain insights into their decision-making processes, consumer preferences and/or motivations. Using a real-world use case, this study highlights the importance of using neuroscience-based methodologies to evaluate packaging design to identify how well the brand is positioning itself on the subconscious level. While results from our study suggest that subjects displayed avoidance behaviour according to the lower frontal alpha asymmetry score, the statistical analysis failed to show significant difference between left and right hemisphere. Regardless of the statistically insignificant EEG findings, relatively longer times to first fixation among the areas on the visual suggest that the visual is not optimally designed and that for obtaining insightful data in product packaging field, relying on eye-tracking techniques is sufficient for reliable insights.

Frontal Alpha Asymmetry in Posttraumatic Stress Disorder: Group Differences Among Individuals With and Without PTSD During an Inhibitory Control Task.

The current study examined frontal alpha asymmetry (FAA) as a marker of approach- and avoidance-related prefrontal activity in participants with and without trauma exposure and posttraumatic stress disorder (PTSD). We investigated FAA in an inhibitory control paradigm (threatening vs nonthreatening cues) under 2 levels of cognitive demand (baseline: images constant within a block of trials; vs filtering: images varied randomly within a block) in 3 groups of participants: individuals with PTSD (n = 16), exposed to trauma but without PTSD (n = 14), and a control group without PTSD or trauma exposure (n = 15). Under low demand (baseline), both PTSD and trauma-exposed participants exhibited significantly greater relative left than right frontal brain activity (approach) to threatening than to nonthreatening images. Under high demand (filtering), no FAA differences were found between threatening and nonthreatening images, but PTSD participants revealed more relative left than right FAA, whereas trauma-exposed participants showed reduced left relative right FAA. In all conditions, healthy controls exhibited reduced left relative to right FAA and no differences between threatening and nonthreatening images. Study findings suggest dysfunctional prefrontal mechanisms of emotion regulation in PTSD, but adaptive prefrontal regulation in trauma-exposed individuals without PTSD.

The relationship between habitual use and real-time emotion regulation strategies in adolescents: Evidence from frontal EEG asymmetry

Past research on emotion regulation has shown that cognitive reappraisal is a healthier and more effective emotion regulation strategy than expressive suppression. However, there are few studies in this field that combine real-time emotion regulation with the use of habitual emotion regulation strategies to observe the patterns of brain activity, and fewer studies focusing on adolescents. Frontal electroencephalography (EEG) asymmetry reflects the difference between brain activation in left and right frontal areas and is widely viewed as an effective biomarker of emotional reactivity and regulation. The present study investigated the asymmetry of the frontal EEG activity during adolescents' emotional regulation, and explored its relationship with adolescents’ habitual use of emotional regulation strategies. Habitual use of cognitive reappraisal and expressive suppression was measured with the emotion regulation questionnaire (ERQ). EEG was recorded from 54 adolescents (24 boys & 30 girls, Mage = 12.59), during the Reactivity and Regulation-Image Task. Results showed that adolescents who used cognitive reappraisal strategies more habitually exhibited greater left frontal asymmetry during real-time enhancement or reduction of negative emotions. In contrast, no significant correlation was found between habitual use of suppression and frontal alpha asymmetry. The results provide neurological evidence that, for adolescents, the use of habitual emotion regulation strategies may affect real-time emotion regulation, adolescents who use cognitive reappraisal more frequently are more capable or more prone to recruit appropriate brain regions in situations that need to regulate negative emotions. This reinforces the importance of the formation and use of correct emotion regulation habits for adolescents.

Effects of system- and media-driven immersive capabilities on presence and affective experience

Virtual reality (VR) is receiving widespread attention as a delivery tool for exposure therapies. The advantage offered by VR over traditional technology is a greater sense of presence and immersion, which magnifies user effects and enhances the effectiveness of exposure-based interventions. The current study systematically examined the basic factors involved in generating presence in VR as compared to standard technology, namely (1) system-driven factors that are exclusive to VR devices while controlling general factors such as field of view and image quality; (2) media-driven factors of the virtual environment eliciting motivational salience through different levels of arousal and valence (relaxing, exciting and fear evoking stimuli); and (3) the effects of presence on magnifying affective response. Participants (N = 14) watched 3 different emotionally salient videos (1 × fear evoking, 1 × relaxing and 1 × exciting) in both viewing modes (VR and Projector). Subjective scores of user experience were collected as well as objective EEG markers of presence (frontal alpha power, theta/beta ratio). Subjective and objective presence was significantly greater in the VR condition. There was no difference in subjective or objective presence for stimulus type, suggesting presence is not moderated by arousal, but may be reliant on activation of motivational systems. Finally, presence did not magnify feelings of relaxation or excitement, but did significantly magnify users’ experience of fear when viewing fear evoking stimuli. This is in line with previous literature showing strong links between presence and generation of fear, which is vital in the efficacy of exposure therapies.

Kültürel Öğeler İçeren Reklamların Beğenisi Demografik Özelliklere Göre Farklılaşır Mı (Does, Likes of Advertisements Containing Cultural Elements, Different According to Demographic Characteristic )

Purpose – The aim of this study is to examine the differentiation of the sense of like (positive motivation- pleasantness) toward video advertisements containing cultural elements, according to the demographic characteristics of the participants, who were born and raised in Turkey and share the same culture. Design/methodology/approach– The experimental phase of the research was carried out with 77 (29F+48M) participants selected by convenient sampling. As a data collection tool in the experiment, the brain signals of the participants were collected by EEG (electroencephalography) against advertising stimuli and the level of like of the participants was measured using the frontal alpha (8-13 Hz) asymmetry method. The demographic information of the participants and the like scores they declared in line with the scale were collected with the form. Findings were obtained by performing independent T-test, Kruskal Wallis H-test and Pearson Correlation analyzes from the data using the SPSS program. Findings – As a result of the study, it was seen that video ads containing cultural elements left a positive impression on individuals who grew up in the same culture. It was observed that women's level of like score was higher than men's. The level of like of individuals raised as a matriarch differs significantly compared to those raised in a patriarchal manner. It was observed that the level of education, marital status and the place of childhood did not differ significantly in the level of like. By making use of the findings, it was seen that women and grew up in a matriarchal environment increased their like for cultural elements. The other finding is that there is no significant relationship between EEG like score and declaration like score. Discussion – In the research carried out, it was seen that the use of cultural elements in advertisements creates a sense of like. In addition, it has been observed that it creates a more effective affect on women and on grow up in a matriarchal environment. This study showed that the cultural elements to be used in advertisements should be emphasized according to the target consumer group for advertising designers and marketers. The other result is that it has been seen that the statements of people about their likes do not reflect the truth. This shows that neuromarketing tools are an effective marketing research tool when they do not objectively reveal the preferences and decisions of the individual.

A Randomized, Triple-Blind, Placebo-Controlled, Crossover Study to Investigate the Efficacy of a Single Dose of AlphaWave® l-Theanine on Stress in a Healthy Adult Population

IntroductionStress is a complex life occurrence essential for survival and goal achievement but can be damaging in excess. Because of the high prevalence of stress in North America, a safe supplement that effectively reduces stress is in demand. The objective of this study was to investigate the efficacy and safety of AlphaWave® l-Theanine on whole-scalp and frontal alpha power, midline theta power, and salivary cortisol in healthy, moderately stressed adults.MethodsThis was a randomized, triple-blind, placebo-controlled, crossover study that consisted of two study periods with a 7-day washout. A single dose of AlphaWave® l-Theanine (200 mg) or placebo was administered. To induce stress, a mental arithmetic test (MAT) was administered before and after the dose. Electroencephalogram, salivary cortisol, blood pressure, heart rate, self-reported stress, adverse events, clinical chemistry, and hematology were assessed to evaluate efficacy and safety.ResultsIncreases in heart rate, blood pressure, and self-reported stress and state anxiety indicated that participants experienced stress during the MAT. AlphaWave® l-Theanine led to a greater increase in frontal region and whole-scalp alpha power 3 h post-dose compared to placebo (p ≤ 0.050). Within groups, there were increases in alpha power, at 3 h with AlphaWave® l-Theanine, over the whole recording and during the eyes-open portions (p ≤ 0.048) of the alpha task. The changes in alpha wave activity are supported by greater decreases in salivary cortisol 1 h post-dose (p < 0.001) with AlphaWave® l-Theanine compared to placebo.ConclusionThis study was conducted during the SARS-CoV-2 pandemic, which has had a rapid and significant effect on both physical and mental health around the world. A single dose of AlphaWave® l-Theanine significantly increased frontal region alpha power compared to placebo in response to an acute stress challenge. These changes are indicative of relaxation in the brain and suggest a calming response. AlphaWave® l-Theanine was found to be safe and well tolerated by participants.Trial RegistrationClinicalTrials.gov identifier NCT04706494.

Differences in the Gamma Interbrain Synchrony Between High and Low Social Anxiety Adolescent-Parent Dyads During Emotional Processing

Behavioral synchrony during social interactions is foundational for the development of social relationships. Behavioral inhibition (BI), characterized by wariness to social novelty and increased anxiety, may influence how children engage in moment-to-moment behavioral synchrony. EEG-derived frontal Alpha asymmetry and Delta-Beta coupling reflect approach-avoidance behavior and emotion regulation, respectively. We examined the relation between intradyadic behavioral synchrony in energy levels and peer gaze, BI, and EEG measures (N = 136, 68 dyads, MeanAge = 10.90 years) during unstructured and structured interactions. Energy levels were negatively synchronized when both children exhibited right Alpha asymmetry. If either child exhibited left Alpha asymmetry, the dyad exhibited more positive synchrony. Peer gaze was less synchronized during the unstructured task with left Alpha asymmetry. Greater positive Delta-Beta coupling in BI children was associated with more peer gaze synchrony. Peer gaze was asynchronous when BI children exhibited negative Delta-Beta coupling and their partner exhibited positive coupling.

The relationship between internalizing problems and acute exercise duration in children with attention-deficit/hyperactivity disorder: The role of frontal alpha asymmetry

BackgroundFrontal alpha asymmetry (FAA) has been associated with the regulation of certain types of internalizing psychopathologies, and is affected by acute aerobic exercise (AE). However, no previous studies have examined the association between FAA and internalizing problems or the effects of acute exercise on FAA in children with ADHD. AimsThis study had two objectives. First, it aimed to examine the relationship between FAA and internalizing behaviors in children with ADHD. Second, it sought to investigate the differential effects of acute AE (30 and 50 min) on FAA. MethodParticipants were assigned to one of the following three groups: 50 min of AE, 30 min of AE, and a control group. Resting electroencephalogram (EEG) data were recorded before and after their respective treatments. EEG data from 43 participants were analyzed to investigate the association between pre-test FAA and internalizing problems as assessed by Child Behavior Checklist scores. Additionally, EEG data from 46 participants were analyzed to examine the effects of acute AE on post-test FAA while controlling for pre-test FAA. ResultsPre-test FAA was found to be significantly negatively associated with internalizing problems, with both hemispheres contributing to this association. Regarding the effects of acute exercise, the 50-minute AE group had highest post-test FAA, reflected by the increased relative left-side frontal activity. ConclusionsThese findings suggest that FAA is a biological marker of internalizing symptoms in children with ADHD, and a 50-minute session of AE can effectively modulate FAA.