The motion of droplet on surface with discontinuous wetting gradient is of great importance for understanding lab-on-a-chip systems and other microfluidic devices. Different wetting gradients are known to be the main influencing factor in the droplet self-driven process, but the effect of different wall structures on the droplet migration process also deserves further investigation. In this paper, we analyze the self-driven process of liquid droplets on a local wetting gradient surface under microgravity conditions using front tracking method. The effects of different driving stripe lengths [Formula: see text], different restrictive stripe lengths [Formula: see text], and different surface wetting gradients Δcos θ on the droplet migration process and droplet morphology are analyzed. A theoretical formula that can predict the lateral spreading length of droplets is also proposed. The results show that different driving stripe length [Formula: see text] lengths and the wetting gradient Δcos θ have significant effects on the migration velocity of droplets, while different restrictive stripe length [Formula: see text] lengths have very significant effects on the final morphological characteristics of droplets. When restrictive stripe length [Formula: see text], the hindering effect generated by the restrictive region ΙΙΙ has more and more significant effects on the morphological structure of droplets in the migration process. When the correction factor ε = 0.735 in the prediction equation, the predicted value calculated by the theoretical equation has a good degree of similarity with the numerical simulation results.
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