Relevance of the problem. Russia's military invasion in Ukraine induced the issue of logistics optimization at the national and regional level. Now, despite the fact of ongoing hostility in Ukraine, it is necessary to build new and optimized logistics system. It is an important component of the country's infrastructure, and its economy`s recovery, which will prevent a prolonged crisis and create the conditions for sustainable development. Problem statement. Conceptual principles of the updated logistics infrastructure building at the regional and national levels require the development of measures for their practical implementation in the process of state reconstruction. This necessitates the development and justification of the algorithm for its application in Ukraine in the future. Analysis of recent research. Analysis of the current position of logistics in Ukraine after the beginning of hostility and Russian aggression has been made. Given that the hostility continues, and there are temporarily occupied territories as well, characterized by the unrated damage and destruction of logistics infrastructure, the official data for the only region completely freed from invaders, namely Kyiv region, has been analyzed. Unsolved parts of the general problem. Thus, quick national logistics infrastructure recovery needs theoretical, methodological and practical justification of the renewed structure at the national and regional level. Study task and objective. The eventual model will be applied in the study to solve the practical task, namely to use the developed methodology and algorithm for selecting potential locations of regional distribution logistics centers to determine their location as the basis of a new logistics map of Ukraine. The main material (study results). Practical adaptation of the developed model for the renewed logistics infrastructure system of Ukraine has been described in the study. Expertise research method has been used to make the territorial binding of the location of regional distribution logistics centers network. On the basis of an expert survey, not only Kyiv, but four other potential locations of regional distribution logistics centers have been identified. It is advisable to redistribute freight flows across the territory of Ukraine through them. They are Odesa, Lviv, Dnipro, and Kharkiv. These centers are the main transport routes connecting Western and Eastern Europe, and Asia. Thus, the distribution model of trade flows and logistics load throughout Ukraine could be forecasted as follows: Central region -> the city of Dnipro; Eastern region the city of Kharkiv; Western region -> the city of Lviv; Southern region -> the city of Odesa; Northern region -> the city of Kyiv. Conclusions. The developed practical algorithm of the renewed system of logistics infrastructure of Ukraine considering its regional features will allow to modernize national economy and its warehouse logistics taking into account foreign experience of similar structural institutions and country`s social-economic characteristics. The proposed and substantiated model with cluster approach has practical topological relationship to specific regions and country in general.