AimToday Cone Beam Computed Tomography (CBCT) has become an important image technique for dento-maxilla facial applications. In the paper a new method to assess the geometric accuracy of these systems was proposed. It uses a free form benchmark model and a non-contact Reverse Engineering (RE) system. MethodThe test geometry chosen for this study was designed in such a way that it simulated human spongy bone, cortical bone, gingiva and teeth and it composed of removable free form parts. It was acquired with a high-resolution laser scanner (D700 Scanner – 3Shape, Denmark). The reference 3D surface models obtained with the laser scanner was compared with the 3D models that were created from a CBCT system (Scanora 3D – Soderex, Finland) and from a traditional Multi-Slice Computed Tomography (MSCT) scanner (LightSpeed VCT 64 Slice – General Electric, USA) at different reconstruction settings, using an iterative closest point algorithm (ICP) in Geomagic® software. ResultsThe comparison between the different pairs of CAD models clearly shows that there is a good overlap between the models. ConclusionsAlthough the results obtained in this study could lead to increase the use of CBCT for an increasing number of dental procedures, the publication of the European Commission guidelines represents a baseline on which the clinicians should rely heavily when considering the use of CBCT in their practice. Clinical SignificanceThe results of this research show that the accuracy of CBCT 3D models is comparable to MSCT 3D models.