Although the spatial patterns of cultural ecosystem services (CES) are often considered in land use management, there is a noticeable disparity in research coverage compared to biophysical ecosystem services (BES). Moreover, there is a lack of research focusing on human perceptions of CES. To address this gap, this study proposed a CES-BES framework that integrates spatial patterns, driving factors of CES, and their interactions with BES, based on the general framework of social and ecological systems. To alleviate the dual pressures of ecological degradation and cultural preservation, this study utilized the constructed CES-BES framework to offer land use recommendations aimed at promoting sustainable development in the Horqin Sandy Land. CES and BES were quantified through a combination of questionnaire surveys, SolVES model and process modeling, including aesthetic, biodiversity, cultural, economic, future, and historical values, as well as net primary productivity, crop production, wind protection, and sand fixation. The results revealed that CES in the Horqin Sandy Land exhibited a discernible pattern of "high in the west and low in the east." Notably, the factors perceived by respondents exerted a more substantial influence on CES than non-perceptual factors. Female respondents showed relatively lower sensitivity to CES overall, but higher sensitivity to biodiversity. Han respondents tended to prioritize biodiversity, while Mongolian respondents were more sensitive to cultural and historical values. Herders exhibited higher sensitivity to biodiversity, while respondents from other occupations showed higher sensitivity to cultural and future values. The influence of land use, topography, and accessibility on different CES was generally similar. All CES showed a positive correlation with elevation, slope, and distance to water, while they showed a negative correlation with distance to roads. Based on the results, the Horqin Sandy Land has been divided into five regions, with development recommendations provided for each region to ensure sustainable development. This study provides a novel perspective and methodological framework for CES supporting territorial spatial governance and land use management, contributing to a more comprehensive understanding of CES.