A large amount of course data has been accumulated in the long-term teaching activities of universities. It is of great research value to use the data resources to analyze the course teaching status and provide decision support for improving the course teaching quality. In this paper, we design and implement a course evaluation system based on association rules and cluster analysis, analyze the functional requirements of the course evaluation system, and pre-process the course evaluation data. Students’ performance data are analyzed by FP-growth association rules, and then clustered by K-means, which can improve the accuracy of data evaluation.The evaluation index system of university English teaching quality under the concept of “Thinking and Government” is established. With the results of the sample survey, the main problems of the evaluation method are summarized and analyzed, and corresponding suggestions are put forward, which provide an important reference for promoting the reform of college English course.