The presence of a large amount of quality-related but hard-to-measure variables usually makes effective monitoring of industrial processes difficult, and even impossible. Soft computing techniques and digital twins can revolutionize standard approaches to solve this issue, even though industrial data are frustrated by nonlinearity, disturbances, and dynamic behaviors. In this light, this paper proposes a data-driven soft sensor with the help of the Fourier amplitude sensitivity test (FAST) and improved probabilistic regularized echo state network (IPRESN), then to twin the quality hardware sensors. Within this framework, the initial step is to rely on the FAST method to measure the collaborated importance of multiple process variables with respect to each quality variable. This quantification facilitates the selection of auxiliary variables for the training of IPRESN. Furthermore, a probabilistic regularization method is learned to improve the robust performance of the echo state network (ESN) by re-designing a new objective function to minimize the mean and variance of the modeling error. Additionally, the whale optimization algorithm (WOA) is improved and then used to optimize the critical hyper-parameters of ESN, thus mitigating the risks associated with suboptimal hyperparameter selection. The effectiveness of the proposed method is verified through a Benchmark Simulation Model 2 (BSM2) and a full-scale wastewater treatment plant data set. The findings show the potential of the proposed method in facilitating digital twin implementations for hardware sensors.