A sirocco fan (forward-curved centrifugal fan), including impeller blades and volute, is designed, and the empirical value ranges of several significant design parameters are discussed and summarized fromthe perspective of both aerodynamics and practical structure. Unsteady-flow numerical simulation and radiated sound-field calculation by indirect boundary element method are combined to evaluate its aerodynamic and acoustic performances. Both the discrete noise source from the rotating impeller and broadband noise source from the volute are considered. Obvious flow separation occurs in the flow passage of impeller blades due to large angle of attack, and the tongue region is the major noise source area due to the small impeller-tongue gap. Therefore, parametric studies for blade installation angle and impeller-tongue gap are performed. Analyses of flow- and sound-field indicate that appropriate reduction of blade geometry incidence angle weakens the flow separation, thereby improving both the aerodynamic and acoustic performances, and reasonable increase of the impeller-tongue gap has a remarkable noise reduction effect for the major noise source area near the volute tongue. The optimized sirocco fan meets the requirement of the industrial project, i.e., the far-field A-weighted sound power level lower than 64.0 dB(A), and achieves larger volume flow rate and total pressure rise. The results also imply that fast steady-flow numerical simulation result is indicative of the acoustic performance to some extent if the acoustic evaluation is urgent. Furthermore, optimization of the key structural parameters in the stage of design is preferable in practical engineering, instead of taking follow-up noise reduction measures.