The inherent anisotropy in shale is an attribute associated with its clay minerals platelets alignment and layering and very common with transversely isotropic (TI) medium. This implies that velocity is fastest along the horizontal axis and slowest along the vertical axis, which could affect velocity signature from sonic tools measurements in deviated wells. This may lead to wrong amplitude variation with offset (AVO) signature, inaccurate depth conversions, seismic-to-well tie difficulty etc. Nineteen (19) wells in Forties field andthirteen (13) in Huntington field were investigated and interpreted for the presence of anisotropy effect within the caprock over the reservoir Forties sands of the Sele (shales) Formation. In order to analyse the Thomsen weak anisotropy parameters (ϵ, γ and δ) per field, wells with closer Sele depth range were considered. The well inclinations ( θ ), average compressional (α) and shear (β) velocities per well were utilised for forward and inverse modelling of Thomsen anisotropy equations. The estimated anisotropy (VTI) parameters and the P-wave ( α o ) and S-wave velocities (βo ) at zero inclinations in Sele Formation for the studied wells are: α o = 2448 ± 15.9 m/s, β o = 1003 ± 34.8 m/s, ϵ = 0.15 ± 0.02, γ = 0.33 ± 0.10, δ = 0.030 ± 0.015 in the Forties field Sele, while α o = 2775 ± 23.6 m/s, β o = 1306 ± 47.9 m/s, ϵ = 0.22 ± 0.02, γ = 0.43 ± 0.14, δ = 0.022 ± 0.018 in the Huntington field. AVO responses were compared, assuming both isotropic and anisotropic P–P reflectivity models. Result shows an increase in AVO gradient for all anisotropic case in both fields. AVO signatures were either completely or averagely masked in both fields using the isotropic assumptions. There is also an increase in AVO gradient for all anisotropic cases in both fields. Velocity decreases of about 1.2% and 3.5% were observed in the Sele Formation for the Forties and Huntington fields respectively for anisotropy. The corrected two-way traveltime (TWT) should in principle allow for a better seismic-to-well tie estimation. Similarly, using the faster deviated velocity (i.e. uncorrected velocity) in any depth conversion would result in under estimation of the actual depth across the field.