Formylation Of Aromatic Compounds Research Articles

Efficient preparation of dichloromethyl alkyl ethers and their application in the formylation of aromatic compounds: Scope and limitations

Practical preparations of dichloromethyl alkyl ethers are described, based on the reaction of alkyl formates with oxalyl chloride in the presence of N-methylformanilide. The method involves a simple procedure that does not require the use of harmful reagents. Dichloromethyl propyl and dichloromethyl butyl ethers represent secure synthetic equivalents to dichloromethyl methyl ether. Formylations of both electron-deficient and electron-rich aromatics with these dichloromethyl alkyl ethers in the presence of AlCl3, FeCl3, or TiCl4 have been systematically investigated. A plausible mechanism of formylation is discussed.

New One-Pot Synthesis of 4-Hydroxybenzaldehyde Derivatives and Picric Acid from 4-Hydroxyphenylglycine with HNO3/H2O

Since aromatic aldehydes are important intermediates in the chemical, pharmaceutical and cosmetic industries, easy and con-venient synthetic methods to synthesize them have been pur-sued. Among the most widely-used methods are formylation of aromatic compounds and oxidation of primary alcohols. Previ-ous reports describe a variety of formylation reagents, including formyl fluoride HCOF and BF

Orthoamides. Part 64. Formylation of Aromatic Compounds by Tris(dichloromethyl)amine and Oligoformylamine Derivatives in the Presence of Superacids.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

Orthoamide, LXIII [1]. Tris(dichlormethyl)amin, ein neues breit anwendbares Formylierungsmittel für Aromaten / Orthoamides, LXIII [1]. Tris(dichloromethyl)amine, a New Formylating Reagent for Aromatic Compounds of Wide Scope

The reagent system formed from tris(dichloromethyl)amine (5) and aluminium chloride allows the formylation of aromatic compounds. The scope of the method is comparable with that of the Olah formylation and the Groß-Rieche procedure, since benzene and even chlorobenzene can be formylated. One formyl group is transferred from 5 to the aromatic nucleus. In order to find optimal reaction conditions, the molar amounts of aromatic compounds, 5 and aluminum chloride were varied as well as reaction temperatures and solvents. The activation of 5 with other Lewis acids is also described

Orthoamide, LX [1]. N,N,N’,N’-Tetraformylhydrazin – ein breit anwendbares Formylierungsmittel für aromatische Verbindungen / Orthoamide, LX [1]. N,N,N’,N’-Tetraformylhydrazine – a Formylation Agent for Aromatic Compounds of Wide Scope

Keywords The reagent system formed from N,N,N’,N’-tetraformylhydrazine (3) and aluminum chloride allows the formylation of aromatic compounds. The scope of the method is comparable with the Olah formylation and the Groß-Rieche procedure, since benzene and fluorobenzene can be formylated. Two formyl groups are transferred from 3 to the aromatic nuclei when a molar ratio 4:1:4 (aluminum chloride/3/aromatic compound) is chosen.

ChemInform Abstract: Formylation of Aromatic Compounds in Superacidic Medium

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

ChemInform Abstract: Formylation of Aromatic Compounds with CO in HSO3F‐SbF5 Under Atmospheric Pressure.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Formylation of aromatic compounds with carbon monoxide in HSO3F-SbF5 uner atmospheric pressure

The formylation of aromatic compounds such as benzene, toluene, xylenes, mesitylene, indan, tetralin, fluorobenzene, chlorobenzene, and bromobenzene was carried out in HSO 3 F-SbF 5 under atmospheric CO pressure at 0 o C. In HS03F-SbF 5 , both formylation and sulfonation took place to give formyl and sulfonyl compounds. In the case of alkylbenzenes, including toluene, xylenes, mesitylene, and tetralin, formylalkylbenzenesulfonyl fluorides, new compounds, were obtained by a one-pot reaction as well as alkylbenzaldehydes, alkylbenzensulfonyl fluorides, and bis(alkylphenyl) sulfones

A new procedure for formylation of less active aromatics

The formylation of aromatic compounds with trifluoromethanesulphonic anhydride/dimethylformamide complex 2 takes place easily as compared to the normal Vilsmeier–Haack reaction.

Formylation of aromatic compounds with hexamethylenetetramine and trifluoroacetic acid

Formylation of aromatic compounds with hexamethylenetetramine and trifluoroacetic acid

The Formylation of Aromatic Compounds by 1 : 2 Adduct of Dimethylformamide with Cyanuric Chloride

ジメチルホルムアミドがつくる多種の付加物の一つとして.Goldは塩化シアヌルとの1:2付加物を得ている。この付加物がオキシ塩化リンとの付加物と同様に,種々の芳香族化合物をホルミル化するためのVilsmeier反応に用いて有効であることを見いだした。しかしこの付加物によるホルミル化の適用性は,本来のVils血eier反応の試剤とくらべてかなり限定されている