Formulary Lists Research Articles

Formulary lists of Meshcheryaks of the Bashkir-Meshcheryak army of 1843–1844 as a source on the military history of the Tatars

Formulary lists of Meshcheryaks of the Bashkir-Meshcheryak army of 1843–1844 as a source on the military history of the Tatars

Министерская канцелярия С. С. Уварова как инструмент управления просвещением в 1830–1840-е годы

The article examines the administrative functions of Sergey Uvarov's ministerial chancellery based on the materials of the clerical office of the Department of Public Education of the 1830-1840s. The functional features of the “special chancellery” of Alexander Golitsyn and the Chancellery of the Minister of Public Education in the studied period are compared. The author demonstrates the results of a statistical study of the reports of the Ministry of Public Education for 1833–1849, from which it follows that the highest burden on the ministerial chancellery took place in the years of crisis for the institution (1839 and 1849). For the first time, information about Uvarov clerks, their career trajectories and social appearance is introduced into academic sphere. On the basis of formulary lists and other sources, an attempt is made to prosopographically study the persons who served in the Office of the Minister of Public Education (1833–1849). The author also presents the results of a content analysis of the materials of the archival fund of the Office of the Minister (RSHA, fund No. 735), on the basis of which conclusions can be drawn about the main areas of work of this institution, fixed not legally, but de facto.

«Нашу семью называли в городе “благословенной семьей”…» (к биографии Александра Николаевича Пыпина)

The work deals with the questions of the biography of the outstanding Russian scientist-humanitarian, academician of the Imperial Academy of Sciences A. N. Pypin (1833–1904). The purpose of the study is to identify and summarize materials about the Saratov period of the scientist’s life, to present the history of his family, to reveal the role of his father and mother in intellectual and spiritual development. The study of a wide range of memoirs, documentary and epistolary sources resulted in establishing that the history of the noble family of the Pypins dates back to 1791. The ancestors on the father’s side, N. D. Pypin, were clerical workers, on the side of the mother A.E. Golubeva they were priests. It is shown that A. N. Pypin was brought up in a religious family, with high moral ideals, in the atmosphere of love and care. The role of parents in the formation of his humanitarian interests is significant. It is noted that the love of books and reading that distinguished Alexander Nikolaevich from an early age came from his family, from his mother, and was a natural necessity for all younger family members. Parents formed a picture of the world of their son by various means. If the mother did so through literature, primary educational knowledge, then the father formed it by means of contact with real life. He introduced his son to the world of peasant life, of serfdom. According to the scientist, N. D. and A. E. Pypins had a significant impact on the formation of his personality, influenced the choice of life priorities. The paper publishes for the first time the primary source about the birth of A. N. Pypin, the record in the metrical book of Saratov Church of the Holy Saviour, the formulary lists of his great-grandfather, grandfather and father.

The role of medicines and therapeutics committees structure in supporting optimal antibacterial use in hospitals in Uganda: A mixed method study.

Although the roles of Medicines and therapeutic committees (MTCs) have been expanding, there is limited information on the role of their structure in optimal antibacterial use in hospitals, especially in low-and-middle-income countries. Our study explored the structure and role of MTC in supporting antibacterial use in regional referral, general hospitals and tertiary private not-for-profit (PNFP) hospitals in Uganda. We conducted an explanatory sequential mixed-method approach with triangulation to explore the structure and functional role of MTCs from August 2019 to February 2020 in hospitals in Uganda. Quantitative data was collected using an interviewer-administered questionnaire among chairpersons or secretaries of MTCs and was analysed using descriptive statistics. We conducted key informant interviews using an interview guide among long-term serving members of MTCs to collect qualitative data which triangulated the quantitative data. The study revealed that sixteen hospitals had successfully established MTCs with an average duration of the MTCs' existence of 5.6 (+2.7) years. The membership of the MTCs varied between 7 and 14, with a median value of 10, and the majority of members in MTCs were pharmacists (15 out of 16) and clinical specialists (13 out of 16). The most frequent subcommittees of the 16 hospitals MTC were supply chain (n = 14), antimicrobial stewardship (n = 13), and infection control (n = 12). Majority (14 out of 16) of the MTCs supported availability and access of antibacterial use by selecting and evaluating antibacterials agents for their formulary lists using established criteria. Additionally, 15 out 16 MTCs conducted antimicrobial stewardship activities to support optimal antimicrobial use. In our study, MTC membership and subcommittees were critical structural components that aided the selection and evaluation antibacterials on hospital formulary lists and they supported optimal antibacterial use through implementing various antimicrobial stewardship activities. There is a need for the Ministry of Health to conduct more training on operationalising MTCs structures in all hospitals.

Pharmaceutical providing of the treatment of children with epilepsy in Ukraine and abroad

The aim: to investigate the pharmaceutical providing for the treatment of epilepsy in children in Ukraine and abroad and to conduct a marketing analysis of the domestic market of antiepileptic drugs.
 Materials and methods: domestic and foreign Internet sources, medical and technological documents on a specific research topic, the regulatory and legal base of Ukraine, materials of the State Formulary of Medicines, the State Register of Medicines of Ukraine were the objects of the study. The methods of marketing analysis, graphic, documentary and analytical generalization were used.
 Results: a comparative analysis of clinical protocols (France, Great Britain and Ukraine) for the treatment of epilepsy in children showed that there are only 12 INNs out of 37 INNs in the country. The analysis of the formulary lists of drugs of Great Britain and Ukraine showed that the BNFC has 32 INNs, and the domestic - 10 INNs. As of October 2022, 287 names of antiepileptic drugs are registered in Ukraine, and 164 of them are allowed in children's practice. The main producers of antiepileptic drugs are India and Ukraine. Children's drugs forms are mainly represented by tablets and capsules - more than 90%. A comparison of the lists of drugs for the treatment of epilepsy from the National List of Essential Medicines of Ukraine, BNFC, WHO Model List of Essential Medicines and WHO Model List of Essential Medicines for Children showed that out of 37 INNs, only 11 INNs are listed in all documents.
 Conclusions: the results prove the need of improvement of pharmaceutical providing of epilepsy treatment in Ukraine. The nomenclature and variety of dosage forms for children's practice need to be expanded. In order to increase the economic availability of epilepsy treatment, it is advisable to update the National List of the main drugs of Ukraine and include new drugs in it, which will make it possible to purchase them at the expense of the State Budget of Ukraine

История церковно-приходских школ Кольского Севера в конце XIX — первой трети XX века в архивных документах

The article presents an overview of archival materials from the collections of the State Archives of the Murmansk region and the National Archives of the Republic of Karelia, identified in the course of archival heuristics in the process of studying the history of the development of parochial schools in the Kola district of the Arkhangelsk province in the late 19th – first third of the 20th centuries. An analysis of the information potential of the following types of historical sources is given: statistical records, clerical records, formulary lists of priests who taught in schools.

Система признаний и поощрений Российской империей бурятской родовой элиты XVIII–XIX вв.

Introduction. The article examines the system of recognition and encouragements adopted by the Russian Empire for representatives of Buryat tribal elites in the 18th–19th centuries. The focus of the study makes it possible to trace key mechanisms to have facilitated the incorporation of Buryat tribal elites into Russia’s corresponding environment. The legalization of official powers of 18th– 19th century Buryat tribal elites was paralleled by that Imperial Russia developed a corresponding system of recognition and encouragements. The latter was not only to consolidate the high social status of the local nobility but rather to facilitate their further incorporation into the Russian power structures. Goals. The paper aims to investigate Imperial Russia’s system of recognition developed for representatives of Buryat tribal elites throughout the 18th and 19th centuries. Materials and methods. The study analyzes archival materials housed at the State Archive of Buryatia, such as employee and formulary lists of Buryat tribal executives, decrees and instructions of His Imperial Majesty on rewards granted to the latter. The research methods employed include the historical comparative and comparative typological ones that have proved instrumental in analyzing the mentioned Russian system, and compiling a content analysis of archival materials involved. Conclusions. The work reveals the special recognition and rewards system was developed to regulate relations with representatives of local Buryat elites and guarantee their integration into imperial structures. The system of awards and distinctions was used by the Russian government to encourage Buryat tribal and clan leaders for certain services rendered to the state, as well as for successfully fulfilled tasks assigned.

Башкирские фамильные антропонимы от названий социальных титулов, званий и чинов: историко-этимологический анализ

Introduction. Exploration of family anthroponyms associated with names of social titles and ranks on the basis of factual materials is of special significance, especially when it comes to examine the former in several essential perspectives. Goals. The study primarily aims at considering family names derived from social titles and ranks in historical /etymological and lexical/semantic perspectives. Restoration of some ancient names that have got completely excluded from the historical anthroponymic system is possible through analysis of surnames recorded in historical documents. The article seeks to determine the actual methods of deriving surnames from social titles and ranks, as well as to establish correspondences between historical facts and transformed (at certain stages of social life) concepts that had been once used to denote such titles and ranks further manifested in anthroponyms. Materials and Methods. The work analyzes surnames derived from titles and ranks registered in the scientific two-volume edition ‘Documents and Materials on Bashkir History, 1836–1842: Formulary Lists of Civil Servants Attached to the Bashkir-Mishar Tatar Host, 1836–1842’. The study employs a number of linguistic methods, such as the descriptive, etymological, comparative, and statistical ones. Results. Thus, the historical and etymological analysis of surnames derived from the onyms хан ~ ҡан ‘khan ~ qan’, бәк ~ бик ‘beg ~ b(e)ik’, бей ‘bey’, батыр ‘ba(gha)tur’, алп, алып ‘alp’, шаҡман ‘shaqman’ makes it possible conclude as to the significance of titles and ranks in the formation of Bashkir anthroponymy. For example, the insight into the onym хан ~ ҡан serving an anthroponymic basis reveals that the institution of khanate had existed in Bashkir society since ancient times, long before the Golden Horde, which resulted in that ҡан (хан) — stemmed family onyms (as well as related phonetic versions of the lexeme) were widespread enough. The paper also shows that surnames containing the title lexeme бик were much more common than those derived from the form бек. Another finding is that quite a share of discovered Bashkir surnames were derived from ranks bestowed to war heroes (батыр, алп, шаҡман, алдар).

Formulary Management Activities and Practice Implications Among Public Sector Hospital Pharmaceutical and Therapeutics Committees in a South African Province.

IntroductionThe World Health Organization identified Pharmaceutical and Therapeutics Committees (PTCs) at district and hospital levels as one of the pivotal models to promote rational use of medicines (RUM). This is endorsed by the Government in South Africa. Formulary development and management is one of the main functions of PTCs. This study aimed to describe the formulary management activities among PTCs in public hospitals in Gauteng Province, South Africa, following initiatives to promote RUM in South Africa.MethodsQualitative, nonparticipatory, observational study, observing 26 PTC meetings. Data were coded and categorized using NVivo9® qualitative data analysis software. Themes and sub-themes were developed. The themes and sub-themes on formulary management are the principal focus of this paper.ResultsMore than half of the observed PTCs reviewed their formulary lists. There was variation in the review process among institutions providing different levels of care. Various aspects were considered for formulary management especially requests for medicines to be added. These included cost considerations (mainly focusing on acquisition costs), evidence-based evaluation of clinical trials, patient safety, clinical experience and changes in the National Essential Medicines List (NEML). The tertiary PTCs mostly dealt with applications for new non-EML medicines, while PTCs in the other hospitals mainly requested removal or addition of EML medicines to the list.ConclusionThis is the first study from Gauteng Province, South Africa, reporting on how decisions are actually taken to include or exclude medicines onto formularies within public sector hospitals providing different levels of care. Various approaches are adopted at different levels of care when adding to- or removing medicines from the formulary lists. Future programs should strengthen PTCs in specialized aspects of formulary management. A more structured approach to formulary review at the local PTC level should be encouraged in line with the national approach when reviewing possible additions to the NEML.

Материалы Идинской степной думы в фондах Музея истории Бурятии им. М. Н. Хангалова

The article is devoted to the description of the fund of the Ida Steppe Duma, stored in the Museum of the History of Buryatia named after M. N. Khangalov. The fund was considered completely lost, therefore it was not used by researchers. The Ida Steppe Duma Foundation is represented by 12 cases, the rest of the materials have been irretrievably lost. The fund stores office documents in decrees, reports, statements, orders, personal and formulary lists, correspondence, etc. from 1787 to the end of the 19th century, from the opening of the Steppe Office to the closing of the Duma. In materials of a thought orders of higher are given organizations, reports of the founders, which contain information about the development of the economy, primarily agriculture, crop structure, number of yards, name lists, population for all 29 clans of the Ida department, statements, explanations of the founders on the waste of money from the Duma and other materials related to economic activities of the Ida Steppe Duma. The Foundation has information on the guard duty at the Tunkinsky distance by the Ida Buryats, the correspondence of the ancestors about the abolition of this duty. According to the materials of the fund, one can trace the appointment, then the election of the main secret. Part materials of the Duma published in the collection of documents «Ida Buryats». The article also describes the personal archive of the main Taisha of the Ida Steppe Duma I. I. Pirozhkov published by G. N. Rumyantsev discovered by him in the funds of the specified museum. Subsequently, the fund was transferred for permanent storage to the State Archive of the Republic of Buryatia.

Are entry year pharmacy students created equally? A comparison between New Zealand and Canada

An international strategy designed to promote access to primary care is the utilisation of community pharmacy to deliver structured minor ailment services (MASs). An understanding of key implementation features of MASs will support effective service delivery and implementation, promote MAS viability, sustainability and overall improvement.The aim of this study is to explore the views and experiences of a range of stakeholders concerning the implementation of MASs in the United Kingdom.A qualitative approach was used to obtain data. Participants were recruited using purposeful and snowball sampling. Stakeholders from five different regions were included. Using the digital recordings of the interviews, thematic content analysis was undertaken.Thirty-three participants agreed to be interviewed. Twenty-nine semi-structured interviews were conducted. Thematic content analysis yielded three major themes, including (1) benefits of MASs, (2) structural challenges associated with MAS design and (3) other implementation factors associated with MAS delivery. Stakeholders recognised the positive impact of the service to improve patient access and care, promote efficiencies, and promote the professional role of the pharmacist. Nevertheless barriers do exist to service delivery and implementation. Stakeholders identified the need to potentially increase the population groups served by MASs, increase the conditions treated and widen their formulary lists. Similarly, marketing strategies needed to be improved to enhance consumer awareness. Stakeholders presented mixed views about whether pharmacists needed to complete clinical training and the need to increase pharmacist's remuneration. In addition the level of healthcare collaboration needed to improve.Several concepts emerged from the investigation to facilitate service delivery. Barriers to service implementation had a variable impact on implementation. Service delivery should function to meet all stakeholder needs and can be achieved through stakeholder collaboration. However, improved marketing to promote consumer awareness together with better collaborative processes can potentially improve MAS implementation.

Социальный портрет подкомория Правобережной Украины (1797-1832 гг.)

The article states that after the division of the Polish–Lithuanian Commonwealth in the territories included in the Russian Empire, all-Russian judicial institutions were entered. After Pavel I came to power, certain elements of the Polish-Lithuanian Commonwealth's judicial tradition, one of which was the Pidcomorious court, headed by a pidcomoriy which was elected by the nobility and withholding on established revenues in accordance with local laws, were restored. The Supreme Council introduced a property, genealogical and official qualifications to the Polish gentry (the latter for young noblemen) during the aristocratic elections.
 The necessary information on the social portrait of the pidcomoriy can be obtained from the formulary lists. It was established that there were two categories of people in the positions: the minority consisted of those who were professionally engaged in jurisprudence and constantly worked in the judicial system (professional judges), the majority were noblemen who did not have the necessary knowledge, while the service did not allow earning (no funds were allocated for themaintenance of the premises, for office expenses, and the amounts earned were negligible). In addition, the Russian authorities constantly controlled their work and demanded a large amount of accountability.
 As a result, in most of the powiats the post for pidcomoriy was held every three years by new people (casual judges). The supreme authority was not interested in creating a permanent judge's corps and didn't form it from the young nobles who were in the service. If during the times of Polish-Lithuanian Commonwealth, candidates for positions held training and service at lower positions in the judicial system, then in the Right-bank Ukraine in the judicial authorities, basically at the posts of clerical servants landless Polish gentlemen served. In the Volhynia Main Court, according to preserved forms, only 16% of the clerks had the appropriate property qualification to apply for elective posts from the nobility. Simultaneously with the performance of the pidcomoriys' professional duties they also defended their material interests and tried to earn in other ways. After the suppression of the Polish uprising, the Russian authorities destroyed the Polish-Lithuanian Commonwealth's judicial system.

Development of recommendations on creating local formulary drug list for children affected with gastritis and duodenitis

An urgent task is to carry out regular quality control and rational prescribing of drugs, changes to the drug formulary lists for the purpose of positive influence on the processes of pharmaceutical provision, especially children affected with gastritis and duodenitis.
 The aim of the work was to create a list of the recommended groups of drugs for further development of the local insurance and formulary drug lists used for treatment of children with gastritis and duodenitis using modern information technologies. Methods of peer reviews, questionnaires, direct observation, modeling, and information analysis were used in the process. The objects of study were regulatory and legislative documents, medication treatments sheets, price lists of wholesale pharmaceutical companies, forms of expert assessments.
 Science-based guidelines for the assessment of the economic costs for the inclusion of medicines in local formulary drug lists of health care institutions to help children with gastritis and duodenitis in the acute stage, in specialized hospitals, taking into account peculiarities of the disease under study at the regional level were formed.
 According to the results of a comprehensive study of pharmaceutical provision for treatment of children with gastritis and duodenitis, in addition to an expert evaluation of medicines, recommendations for the creation of a local formulary drug list were made and recommended list of drug groups was determined by 15 INN drugs to be used in the development of a local drug formulary list for pharmacotherapy of the pathology under study.

A qualitative study of stakeholder views and experiences of minor ailment services in the United Kingdom.

An international strategy designed to promote access to primary care is the utilisation of community pharmacy to deliver structured minor ailment services (MASs). An understanding of key implementation features of MASs will support effective service delivery and implementation, promote MAS viability, sustainability and overall improvement. The aim of this study is to explore the views and experiences of a range of stakeholders concerning the implementation of MASs in the United Kingdom. A qualitative approach was used to obtain data. Participants were recruited using purposeful and snowball sampling. Stakeholders from five different regions were included. Using the digital recordings of the interviews, thematic content analysis was undertaken. Thirty-three participants agreed to be interviewed. Twenty-nine semi-structured interviews were conducted. Thematic content analysis yielded three major themes, including (1) benefits of MASs, (2) structural challenges associated with MAS design and (3) other implementation factors associated with MAS delivery. Stakeholders recognised the positive impact of the service to improve patient access and care, promote efficiencies, and promote the professional role of the pharmacist. Nevertheless barriers do exist to service delivery and implementation. Stakeholders identified the need to potentially increase the population groups served by MASs, increase the conditions treated and widen their formulary lists. Similarly, marketing strategies needed to be improved to enhance consumer awareness. Stakeholders presented mixed views about whether pharmacists needed to complete clinical training and the need to increase pharmacist's remuneration. In addition the level of healthcare collaboration needed to improve. Several concepts emerged from the investigation to facilitate service delivery. Barriers to service implementation had a variable impact on implementation. Service delivery should function to meet all stakeholder needs and can be achieved through stakeholder collaboration. However, improved marketing to promote consumer awareness together with better collaborative processes can potentially improve MAS implementation.

«Зная порывы Его Высочества… я поставлю часовых и помещу Великого Князя в царских комнатах вокзала железной дороги». Неравный брак внука императора Николая I и дочери оренбургского полицеймейстера А. Г. Дрейера

The article presents documents from archival fonds of the State Archive of the Orenburg Region that narrate little-known facts of the biography of Alexander Gustavovich Dreyer, head of the Orenburg police and public figure, whose life was closely intertwined with the fate of Imperial family offspring Nikolai Konstantinovich Romanov. The significance of the matter lies in the opportunity to make known to contemporaries the outstanding personality of the Orenburg Polizeimeister through a variety of situations - not only in the service, but in the everyday life as well. Alexander Dreyer made a significant contribution to the development of Orenburg and the Orenburg region. A competent, energetic, and non-partisan man, he was actively involved in the creation of the city branch of the Red Cross, the St. Olga orphanage, in the improvement of the boulevard on the bank of the Ural and in many other beneficial activities. In 1877 Grand Duke Nikolai Konstantinovich, the grandson of Nicholas I, was placed under the secret surveillance of the Orenburg police. He fell in love with Alexander Dreyer’s daughter Nadezhda and wed her secretly. In their article the authors attempt to cover the main periods in the life of A.G. Dreyer. Particular attention is paid to the period of 1878-1881, which was a hard time for the family. The documents of the Orenburg gubernia administration, the Orenburg city board (uprava), the Orenburg gendarmerie administration, the office of the Bishop of Orenburg and Ural, and the Orenburg assembly of the nobility from the State Archive of the Orenburg Region, that are presented in the article, have not previously been published. To recreate Dreyer’s biography, two formulary lists (for 1872 and 1878) were used, as well as documents on entering retired Major-General A.G. Dreyer into the genealogical book of the Orenburg gubernia noblity for 1888. In addition to the documents, Orenburg periodicals were studied. Obituaries published after the death of A.G. Dreier, indicate that the inhabitants of the steppe region were sincerely grieved and tried to honor his memory with kind words. In this case, the obituary, being a historical source, provides the researchers with valuable information. A.G. Dreyer's autographs were also discovered; they are dated 1875. Unfortunately, it was impossible to find photographs of A.G. Dreyer.

Development of one paediatric and one neonatal formulary list in hospital settings.

The aim of this study is to describe the stepwise process towards creating two formulary lists: one for paediatric and one for neonatal patients covering common diseases in hospital settings. This study presents the concept for developing a formulary list, namely how to: (1) organize the editorial board, (2) procure drug consumption data and database management, including information on labelling status, dosing options, excipients and problematic adverse events, current guidelines, evidence and price, (3) develop the first edition for the formulary list and formulary manual, and (4) to establish a paediatric sub-committee within the Regional Drug and Therapeutic Committee to maintain and continually develop the two formularies. The total number of drugs was 411 ATC level 5, which covers 1097 unique item numbers prior to the paediatric formulary list, of which 263 item numbers were included in the final list. In neonates, 201 drugs ATC level 5 were evaluated, covering 348 unique item numbers, of which 104 item numbers were included in the final neonatal formulary list. Eighty-eight percent of the included drugs in the paediatric formulary were licensed to children (not specified by age group), 2% were unlicensed in Denmark, and 7% were extemporaneous preparations. For neonates, the percentage was 48%, 4% and 16%, correspondingly. The process is time-consuming as studies are lacking and age-appropriate dosage forms and concentrations differ amongst countries. Nevertheless, the process should be somewhat similar between countries, albeit different drugs may be selected for the final formulary lists.

The study of "budget impact" of antiglaucoma medicines, recommended for inclusion in formulary and insurance lists

The study of "budget impact" of antiglaucoma medicines, recommended for inclusion in formulary and insurance lists

ЕКСПЕРТНА ОЦІНКА ЛІКАРСЬКИХ ЗАСОБІВ ГРУПИ S01E «ПРОТИГЛАУКОМНІ ПРЕПАРАТИ ТА МІОТИКИ»

Проведено анкетування 280 лікарів-спеціалістів (офтальмологів та лікарів загальної практики - сімейної медицини) з метою експертної оцінки препаратів групи S01E «Протиглаукомні препарати та міотики». Розраховано сумарні та середні оцінкові характеристики кожного з досліджуваних препаратів за показниками ефективності, наявності побічної дії, фактичної вірогідності призначення препарату на сьогодні, перспективності застосування препарату, наявності в аптечній мережі. Згідно з отриманими даними здійснено ранжування протиглаукомних препаратів на групи високої, середньої та низької доцільності включення у формулярні та страхові переліки

ВИКОРИСТАННЯ БАЗ ДАНИХ ДЛЯ ОБРАХУВАННЯ РЕЙТИНГУ ПЕРЕВАГ СЕРЕД ПРАПАРАТІВ-АНАЛОГІВ

<p>The proposed software system has several characteristics that allow it to be recommended for widespread use. Note the ability to quickly analyze the range of drugs and the formation of formulary lists at different levels of medical care, their regular review for timely adjustments in terms of pharmacological and economic efficiency, work with the proposed software requires no special training of medical and pharmaceutical workers on the theory and practice of pharmaco-economic studies.</p>

Analysis of organizational and medical documents and formulary lists regulating medical support of pregnant women

Analysis of organizational and medical documents and formulary lists regulating medical support of pregnant women