Ketimine Formation Research Articles

Imino‐bridged heterocycles. II. Regiospecific synthesis of the 11H‐benzo[5,6]cyclohepta[1,2‐c]pyridin‐6,11‐imine and 5H‐benzo[4,5]cyclohepta[1,2‐b]pyridin‐5,10‐imine systems

AbstractRegiospecific synthetic pathways for two of the eight isomeric benzocycloheptapyridinimines have been developed based upon intramolecular acid catalyzed additions between an amine function and an internal olefin. The requisite amines were generated from known tricyclic ketones by ketimine formation followed by sodium borohydride reduction.

Iodination Reactions of Ketones in the Reversed Micellar Systems of Dodecylammonium Propionate in Hexane

Abstract The iodination reactions of ketones in the reversed micellar systems of dodecylammonium propionate (DAP) in hexane were studied at 25.0 °C in relation to the enzymatic function of aldolase or enolase. The reaction rate in the DAP reversed micellar system is 106–107 times greater than that in the system without DAP, 100 times greater even in comparison with that in DAP aqueous system at pH 6.8. As in the ammonium ion catalyzed reaction in aqueous media, the reaction in the presence of DAP proceeds via ketimine formation between ammonium groups of DAP and acetone and subsequent enolization of ketimine to enamine, which reacts very rapidly with iodine. The catalytic effect of DAP reversed micellar system in each reaction step was discussed. Further, this reversed micellar system shows a marked selectivity for acetone as compared with higher analogs.

The photochemical formation of ketimines from aromatic ketoximes

The photochemical formation of ketimines from aromatic ketoximes

Dehydrative Condensation of Ketones with Ammonia over Thoria -Selective Ketimine Formation with Benzophenone-

Dehydrative condensation of cyclohexanone and benzophenone with ammonia over thoria prepared from oxalate have been studied.In the case of cyclohexanone, various products such as cyclohexenylcyclohexanone and some nitrogen-containing compounds were obtained at 365-410C while a trace amount of cyclohexanoneimine was detected.Benzophenone condensed selectively with ammonia to form ketimine in high yield at 310v 4200C. Effects of temperature, feed rate, partial pressure of ketone and ammonia are shown in Figs.2-5. Yields of ketimine were reached, for example, 80.5% and 44.0% for O.3X10-2atm and 3.0X10-2 atm of ketone, respectively, in the presence of exess ammonia at 365C. A value of apParent equilibrium constant was estimated to be K=0, 035 0, 002 at 365C.The selective condensation behavior of benzophenone with ammonia was attributed to the lack of a-hydrogen which was necessary to form aldol-type condensation products.

Isonitrile complexes of chromium(0) and molybdenum(0): characterisation and reactivity

The preparation of a series of isonitrile complexes, [(CO)6 –xM(CNR)x](x= 1–3; M = Cr, Mo; R = Me, Et, Pri, C6H11, But, p-tolyl, Ph, p-ClC6H4) is reported. The results of spectroscopic (i.r., u.v., mass, and n.m.r.— particularly aromatic solvent induced shifts) and electrochemical measurements are employed to assess the nature of the bonding in these systems. It is shown that the contribution of (d→π*)π-bonding is negligible and that variations in the donor strength of the isonitrile ligand are principally responsible for the changes observed. The compounds (RNC)Cr(CO)5 do not react with weak nucleophiles (amines, alcohols). Ketimine formation does not result from the reaction between (RNC)Cr(CO)5 and a silane in the presence of pyridine. The reaction between (RNC)2Cr(CO)4 and (Me2PCH2)2(dmpe) affords cis-(RNC)2(dmpe)Cr(CO)2 as the principal product, together with (dmpe)2Cr(CO)3.

Studies on the Mechanism of Oxime and Ketimine Formation1

Studies on the Mechanism of Oxime and Ketimine Formation¹

Anomalous Mutarotation of Salts of Reychler's Acid. II. Ketimine Formation from Amine Salts of d-Camphor-10-sulfonic Acid

Anomalous Mutarotation of Salts of Reychler's Acid. II. Ketimine Formation from Amine Salts of d-Camphor-10-sulfonic Acid