Bulge Formation Research Articles

Morphology and star formation in IllustrisTNG: the build-up of spheroids and discs

ABSTRACT Using the IllustrisTNG simulations, we investigate the connection between galaxy morphology and star formation in central galaxies with stellar masses in the range 109–1011.5 M⊙. We quantify galaxy morphology by a kinematical decomposition of the stellar component into a spheroidal and a disc component (spheroid-to-total ratio, S/T) and by the concentration of the stellar mass density profile (C82). S/T is correlated with stellar mass and star formation activity, while C82 correlates only with stellar mass. Overall, we find good agreement with observational estimates for both S/T and C82. Low- and high-mass galaxies are dominated by random stellar motion, while only intermediate-mass galaxies (M⋆ ≈ 1010–1010.5 M⊙) are dominated by ordered rotation. Whereas higher mass galaxies are typical spheroids with high concentrations, lower mass galaxies have low concentration, pointing to different formation channels. Although we find a correlation between S/T and star formation activity, in the TNG model galaxies do not necessarily change their morphology when they transition through the green valley or when they cease their star formation, this depending on galaxy stellar mass and morphological estimator. Instead, the morphology (S/T and C82) is generally set during the star-forming phase of galaxies. The apparent correlation between S/T and star formation arises because earlier forming galaxies had, on average, a higher S/T at a given stellar mass. Furthermore, we show that mergers drive in situ bulge formation in intermediate-mass galaxies and are responsible for the recent spheroidal mass assembly in the massive galaxies with M⋆ > 1011 M⊙. In particular, these massive galaxies assemble about half of the spheroidal mass while star-forming and the other half through mergers while quiescent.

PADDLE SHAPE OPTIMIZATION FOR HOLE-FLANGING BY PADDLE FORMING THROUGH THE USE OF A PREDEFINED STRAIN PATH IN FINITE ELEMENT ANALYSIS

This research investigates a novel hole-flanging process by paddle forming through the use of finite element (FE) simulations. Paddles of different shapes rotating at high speeds were used to deform clamped sheets with pre-drilled holes at their centers. The results of the simulations show that the paddle shape determines the geometry and principal strains of the formed flanges. A convex-shaped paddle forms flanges with predominant strains in the left quadrant of the forming limit diagram (FLD). However, the convex paddle promotes unwanted bulge formation at the clamped end of the flange. A concave paddle forms flanges with no bulge but the principal strains of elements in the middle section of the flange are in the right quadrant of the FLD which indicates an increased probability for crack occurrence. An optimization of the paddle shape was conducted to prevent bulging at the clamped end while avoiding crack occurrence. The paddle shape was optimized by mapping the deformation of some elements along the flange length to a pre-defined strain path on the FLD while maintaining the bulge height within the desired geometric tolerance. The radii and lengths of the paddle edge were varied to obtain an optimum paddle shape.

Features of the fossil tidal bulge formation for the early moon

The limitations imposed on the orbit and the distribution of the density of the early Moon by present-day measurements of its fossil tidal bulge are studied. A semi-analytical method has been developed for calculating gravitational potentials, which makes it possible to investigate the equi-potential surfaces of a self gravitating inhomogeneous mass in an external field. Universal expressions are obtained for the two-layer mantle-crust model of the early Moon, which makes it possible to make general estimates of the density of the upper crust and semiaxes of its orbit in the case of tidal capture by the Earth.

Assessment of acid-base status and calcification risk after hemodialysis session

Arabia Terra is a region of Mars where signs of past-water occurrence are recorded in several landforms. Broad and local scale geomorphological, compositional and hydrological analyses point towards pervasive fluid circulation through time. In this work we focus on mound fields located in the interior of three casters larger than 40 km (Firsoff, Kotido and unnamed crater 20 km to the east) and showing strong morphological and textural resemblance to terrestrial mud volcanoes and spring-related features. We infer that these landforms likely testify the presence of a pressurized fluid reservoir at depth and past fluid upwelling. We have performed morphometric analyses to characterize the mound morphologies and consequently retrieve an accurate automated mapping of the mounds within the craters for spatial distribution and fractal clustering analysis. The outcome of the fractal clustering yields information about the possible extent of the percolating fracture network at depth below the craters. We have been able to constrain the depth of the pressurized fluid reservoir between ∼2.5 and 3.2 km of depth and hence, we propose that mounds and mounds alignments are most likely associated to the presence of fissure ridges and fluid outflow. Their process of formation is genetically linked to the formation of large intra-crater bulges previously interpreted as large scale spring deposits. The overburden removal caused by the impact crater formation is the inferred triggering mechanism for fluid pressurization and upwelling, that through time led to the formation of the intra-crater bulges and, after compaction and sealing, to the widespread mound fields in their surroundings.

Vortex competition in coastal outflows

Experiments and field observations have shown that there are at least two modes of behavior for river plumes. In many cases, the plume turns to the right (in the Northern Hemisphere) on leaving the river mouth and follows the direction of Kelvin-wave propagation. Alternatively, a “bulge” can form in the plume and a fraction of the outflow volume becomes trapped near the mouth. This paper discusses how bulge formation can be affected by the vorticity profile at the river mouth. Due to the image effect, regions of cyclonic vorticity tend to propagate rightwards, whereas regions of anticyclonic vorticity propagate leftward upon exit from the source. If an outflow consists of regions of cyclonic vorticity to the left of regions of anticyclonic vorticity, the two image effects are in competition. We explore this phenomenon using a quasi-geostrophic model with piecewise-constant potential vorticity, which allows the vorticity profile at the source to be set as part of the problem. We present analytic solutions valid in the source region and at the head of the plume and show that all of the outflow travels rightwards if and only if the region of cyclonic vorticity is dominant. The initial-value problem for the model is integrated numerically using the method of contour dynamics, and the full parameter space is explored. We find that if the cyclonic and anticyclonic contributions cancel, as in the experiments of Avicola and Huq (2003), then steady solutions are unstable and a bulge can form downstream of the river mouth.

ROCK1 but not LIMK1 or PAK2 is a key regulator of apoptotic membrane blebbing and cell disassembly.

Many cell types are known to undergo a series of morphological changes during the progression of apoptosis, leading to their disassembly into smaller membrane-bound vesicles known as apoptotic bodies (ApoBDs). In particular, the formation of circular bulges called membrane blebs on the surface of apoptotic cells is a key morphological step required for a number of cell types to generate ApoBDs. Although apoptotic membrane blebbing is thought to be regulated by kinases including ROCK1, PAK2 and LIMK1, it is unclear whether these kinases exhibit overlapping roles in the disassembly of apoptotic cells. Utilising both pharmacological and CRISPR/Cas9 gene editing based approaches, we identified ROCK1 but not PAK2 or LIMK1 as a key non-redundant positive regulator of apoptotic membrane blebbing as well as ApoBD formation. Functionally, we have established an experimental system to either inhibit or enhance ApoBD formation and demonstrated the importance of apoptotic cell disassembly in the efficient uptake of apoptotic materials by various phagocytes. Unexpectedly, we also noted that ROCK1 could play a role in regulating the onset of secondary necrosis. Together, these data shed light on both the mechanism and function of cell disassembly during apoptosis.

Abundances of disk and bulge giants from high-resolution optical spectra

Context. The formation and evolution of the Galactic bulge and the Milky Way is still a debated subject. Observations of the X-shaped bulge, cylindrical stellar motions, and the presumed existence of a fraction of young stars in the bulge have suggested that it formed through secular evolution of the disk and not through gas dissipation and/or mergers, as thought previously. Aims. Our goal was to measure the abundances of six iron-peak elements (Sc, V, Cr, Mn, Co, and Ni) in the local thin and thick disks and in the bulge. These abundances can provide additional observational constraints for Galaxy formation and chemical evolution models, and help us to understand whether the bulge has emerged from the thick disk or not. Methods. We use high-resolution optical spectra of 291 K giants in the local disk mostly obtained by the FIES at NOT (signal-to-noise ratio (S/N) of 80–100) and 45 K giants in the bulge obtained by the UVES/FLAMES at VLT (S/N of 10–80). The abundances are measured using Spectroscopy Made Easy (SME). Additionally, we apply non-local thermodynamic equilibrium corrections to the ratios [Mn/Fe] and [Co/Fe]. The thin and thick disks were separated according to their metallicity, [Ti/Fe], as well as proper motions and the radial velocities from Gaia DR2. Results. The trend of [V/Fe] vs. [Fe/H] shows a separation between the disk components, being more enhanced in the thick disk. Similarly, the [Co/Fe] vs. [Fe/H] trend shows a hint of an enhancement in the local thick disk. The trends of V and Co in the bulge appear to be even more enhanced, although within the uncertainties. The decreasing value of [Sc/Fe] with increasing metallicity is observed in all the components, while our [Mn/Fe] value steadily increases with increasing metallicity in the local disk and the bulge instead. For Cr and Ni we find a flat trend following iron for the whole metallicity range in the disk and the bulge. The ratio of [Ni/Fe] appears slightly overabundant in the thick disk and the bulge compared to the thin disk, although the difference is minor. Conclusions. The somewhat enhanced ratios of [V/Fe] and [Co/Fe] observed in the bulge suggest that the local thick disk and the bulge might have experienced different chemical enrichment and evolutionary paths. However, we are unable to predict the exact evolutionary path of the bulge solely based on these observations. Galactic chemical evolution models could, on the other hand, allow us to predict them using these results.

Comparing galaxy morphology in hydrodynamical simulation and in semi-analytic model

We compare galaxy morphology predicted by the Illustris hydrodynamical simulation and a semi-analytic model (SAM) grafted in the halo merger trees from the Illustris-Dark matter simulation. Morphology is classified according to the luminous profile and the kinematic bulge-to-total ratio for Illustris galaxy, and the bulge-to-total stellar mass ratio for SAM galaxy. For late-type galaxies in the Illustris catalogue, most of their counterparts in the SAM model have the same type, and the consistency between two models is higher for lower mass galaxies. For early-type (ET) galaxies in Illustris, the consistency is quite low for the counterparts except for most massive galaxies. By comparing in detail the growth histories of some matched galaxy pairs of Milky Way mass in Illustris and the SAM model, we notice two aspects of differences in determining galaxy morphology between the two galaxy formation implementations. First, in the SAM, major merger and frequent minor mergers result in the growth of bulges and turn the galaxy into ET, while bulge formation is not connected to mergers as tightly as in SAM for the Illustris galaxies. In addition, the satellite stellar mass can decrease significantly due to tidal stripping before merging into the central galaxy in Illustris, while it does not decrease in the SAM model. This results in less mergers with large (stellar) mass ratios in the Illustris simulation, and less effect of mergers on shaping galaxy morphology.

Distribution of Mechanical Stress in the Escherichia Coli Cell Envelope

The cell envelope in Gram-negative bacteria comprises two distinct membranes with a cell wall between them. There has been a growing interest in the mechanical adaptation of this cell envelope to the osmotic pressure (or turgor pressure), which is generated by the difference in the concentration of solutes between the cytoplasm and the external environment. However, it remains unexplored how the cell wall, the inner membrane (IM), and the outer membrane (OM) effectively protect the cell from this pressure by bearing the resulting surface tension, thus preventing the formation of inner membrane bulges, abnormal cell morphology, spheroplasts and cell lysis.In this study, we have used molecular dynamics (MD) simulations combined with experiments to resolve how and to what extent models of the IM, OM, and cell wall respond to changes in surface tension. We calculated the area compressibility modulus of all three components in simulations from tension-area isotherms. Experiments on monolayers mimicking individual leaflets of the IM and OM were also used to characterize their compressibility.While the membranes become softer as they expand, the cell wall exhibits significant strain stiffening at moderate to high tensions. We integrate these results into a model of the cell envelope in which the OM and cell wall share the tension at low turgor pressure (0.3 atm) but the tension in the cell wall dominates at high values ( > 1 atm).

Features of the Fossil Tidal Bulge Formation for the Early Moon

The limitations imposed on the orbit and the distribution of the density of the early Moon by present-day measurements of its fossil tidal bulge are studied. A semi-analytical method has been developed for calculating gravitational potentials, which makes it possible to investigate the equi-potential surfaces of a self gravitating inhomogeneous mass in an external field. Universal expressions are obtained for the two-layer mantle-crust model of the early Moon, which makes it possible to make general estimates of the density of the upper crust and semiaxes of its orbit in the case of tidal capture by the Earth.

Slt, MltD, and MltG of Pseudomonas aeruginosa as Targets of Bulgecin A in Potentiation of β-Lactam Antibiotics.

The interplay between the activities of lytic transglycosylases (LTs) and penicillin-binding proteins (PBPs) is critical for the health of the bacterial cell wall. Bulgecin A (a natural-product inhibitor of LTs) potentiates the activity of β-lactam antibiotics (inhibitors of PBPs), underscoring this intimate mechanistic interdependence. Bulgecin A in the presence of an appropriate β-lactam causes bulge deformation due to the formation of aberrant peptidoglycan at the division site of the bacterium. As Pseudomonas aeruginosa, a nefarious human pathogen, has 11 LT paralogs, the answer as to which LT activity correlates with β-lactam potentiation is important and is currently unknown. Growth of P. aeruginosa PAO1 strains harboring individual transposon-insertion mutants at each of the 11 genes for LTs, in the presence of the β-lactam antibiotic ceftazidime or meropenem, implicated the gene products of slt, mltD, and mltG (of the 11), in bulge formation and potentiation. Hence, the respective enzymes would be the targets of inhibition by bulgecin A, which was indeed documented. We further demonstrated by imaging in real time and by SEM that cell lysis occurs by the structural failure of this bulge. Upon removal of the β-lactam antibiotic prior to lysis, P. aeruginosa experiences delayed recovery from the elongation and bulge phenotype in the presence of bulgecin A. These observations argue for a collaborative role for the target LTs in the repair of the aberrant cell wall, the absence of activities of which in the presence of bulgecin A results in potentiation of the β-lactam antibiotic.

Bulging in incremental sheet forming of cold bonded multi-layered Cu clad sheet: Influence of forming conditions and bending

Abstract Bulge is a defect that causes geometrical inaccuracy and premature failure in the innovative incremental sheet forming (ISF) process. This study has two-fold objectives: (1) knowing the bulging behavior of a Cu clad tri-layered steel sheet as a function of forming conditions, and (2) analyzing the bending effect on bulging in an attempt to identify the associated mechanism. A series of ISF tests and bending analysis are performed to realize these objectives. From the cause-effect analysis, it is found that bulge formation in the layered sheet is sensitive to forming conditions in a way that bulging can be minimized utilizing annealed material and performing ISF with larger tool diameter and step size. The bending under tension analysis reveals that the formation of bulge is an outgrowth of bending moment that the forming tool applies on the sheet during ISF. Furthermore, the magnitude of bending moment depending upon the forming conditions varies from 0.046 to 10.24 N·m/m and causes a corresponding change in the mean bulge height from 0.07 to 0.91 mm. The bending moment governs bulging in layered sheet through a linear law. These findings lead to a conclusion that the bulge defect can be overcome by controlling the bending moment and the formula proposed can be helpful in this regards.

Modelling of surface formation mechanism during burnishing of aluminium

Burnishing is a finishing process which levels the roughness of machined surfaces and increases the hardness by micro-forming. In this paper, a novel two-dimensional finite element model for the diamond ball burnishing process on aluminium is presented, which allows a prediction of the surface structure. The force, step over distance, and tool geometry during the burnishing process are taken into account by the model and the results are verified by experimental investigations. The verification shows that the model is able to predict all geometrical surface aspects like roughness, sinking-in and bulge formation for reasonable process parameters.

Fluids mobilization in Arabia Terra, Mars: Depth of pressurized reservoir from mounds self-similar clustering

Arabia Terra is a region of Mars where signs of past-water occurrence are recorded in several landforms. Broad and local scale geomorphological, compositional and hydrological analyses point towards pervasive fluid circulation through time. In this work we focus on mound fields located in the interior of three casters larger than 40 km (Firsoff, Kotido and unnamed crater 20 km to the east) and showing strong morphological and textural resemblance to terrestrial mud volcanoes and spring-related features. We infer that these landforms likely testify the presence of a pressurized fluid reservoir at depth and past fluid upwelling. We have performed morphometric analyses to characterize the mound morphologies and consequently retrieve an accurate automated mapping of the mounds within the craters for spatial distribution and fractal clustering analysis. The outcome of the fractal clustering yields information about the possible extent of the percolating fracture network at depth below the craters. We have been able to constrain the depth of the pressurized fluid reservoir between ∼2.5 and 3.2 km of depth and hence, we propose that mounds and mounds alignments are most likely associated to the presence of fissure ridges and fluid outflow. Their process of formation is genetically linked to the formation of large intra-crater bulges previously interpreted as large scale spring deposits. The overburden removal caused by the impact crater formation is the inferred triggering mechanism for fluid pressurization and upwelling, that through time led to the formation of the intra-crater bulges and, after compaction and sealing, to the widespread mound fields in their surroundings.

Angular momentum evolution of bulge stars in disc galaxies in NIHAO

We study the origin of bulge stars and their angular momentum (AM) evolution in 10 spiral galaxies with baryonic masses above $10^{10}$M$_\odot$ in the NIHAO galaxy formation simulations. The simulated galaxies are in good agreement with observations of the relation between specific AM and mass of the baryonic component and the stellar bulge-to-total ratio ($B/T$). We divide the star particles at $z=0$ into disc and bulge components using a hybrid photometric/kinematic decomposition method that identifies all central mass above an exponential disc profile as the `bulge'. By tracking the bulge star particles back in time, we find that on average 95\% of the bulge stars formed {\it in situ}, 3\% formed {\it ex situ} in satellites of the same halo, and only 2\% formed {\it ex situ} in external galaxies. The evolution of the AM distribution of the bulge stars paints an interesting picture: the higher the final $B/T$ ratio, the more the specific AM remains preserved during the bulge formation. In all cases, bulge stars migrate significantly towards the central region, reducing their average galactocentric radius by roughly a factor 2, independently of the final $B/T$ value. However, in the higher $B/T$ ($\gtrsim0.2$) objects, the velocity of the bulge stars increases and the AM of the bulge is almost conserved, whereas at lower $B/T$ values, the velocity of the bulge stars decreases and the AM of bulge reduces. The correlation between the evolution of the AM and $B/T$ suggests that bulge and disc formation are closely linked and cannot be treated as independent processes.

Inhibition of histone methyltransferase EZH2 in Schistosoma mansoni in vitro by GSK343 reduces egg laying and decreases the expression of genes implicated in DNA replication and noncoding RNA metabolism.

BackgroundThe possibility of emergence of praziquantel-resistant Schistosoma parasites and the lack of other effective drugs demand the discovery of new schistosomicidal agents. In this context the study of compounds that target histone-modifying enzymes is extremely promising. Our aim was to investigate the effect of inhibition of EZH2, a histone methyltransferase that is involved in chromatin remodeling processes and gene expression control; we tested different developmental forms of Schistosoma mansoni using GKS343, a selective inhibitor of EZH2 in human cells.Methodology/Principal findingsAdult male and female worms and schistosomula were treated with different concentrations of GSK343 for up to two days in vitro. Western blotting showed a decrease in the H3K27me3 histone mark in all three developmental forms. Motility, mortality, pairing and egg laying were employed as schistosomicidal parameters for adult worms. Schistosomula viability was evaluated with propidium iodide staining and ATP quantification. Adult worms showed decreased motility when exposed to GSK343. Also, an approximate 40% reduction of egg laying by GSK343-treated females was observed when compared with controls (0.1% DMSO). Scanning electron microscopy showed the formation of bulges and bubbles throughout the dorsal region of GSK343-treated adult worms. In schistosomula the body was extremely contracted with the presence of numerous folds, and growth was markedly slowed. RNA-seq was applied to identify the metabolic pathways affected by GSK343 sublethal doses. GSK343-treated adult worms showed significantly altered expression of genes related to transmembrane transport, cellular homeostasis and egg development. In females, genes related to DNA replication and noncoding RNA metabolism processes were downregulated. Schistosomula showed altered expression of genes related to cell adhesion and membrane synthesis pathways.Conclusions/SignificanceThe results indicated that GSK343 presents in vitro activities against S. mansoni, and the characterization of EZH2 as a new potential molecular target establishes EZH2 inhibitors as part of a promising new group of compounds that could be used for the development of schistosomicidal agents.

A diffuse interface model for the analysis of propagating bulges in cylindrical balloons

With the aim to characterize the formation and propagation of bulges in cylindrical rubber balloons, we carry out an expansion of the nonlinear axisymmetric membrane model assuming slow axial variations. We obtain a diffuse interface model similar to that introduced by van der Waals in the context of liquid–vapour phase transitions. This provides a quantitative basis to the well-known analogy between propagating bulges and phase transitions. The diffuse interface model is amenable to numerical as well as analytical solutions, including linear and nonlinear bifurcation analyses. Comparisons to the original membrane model reveal that the diffuse interface model captures the bulging phenomenon very accurately, even for well-localized phase boundaries.

Distribution of mechanical stress in the Escherichia coli cell envelope

The cell envelope in Gram-negative bacteria comprises two distinct membranes with a cell wall between them. There has been a growing interest in understanding the mechanical adaptation of this cell envelope to the osmotic pressure (or turgor pressure), which is generated by the difference in the concentration of solutes between the cytoplasm and the external environment. However, it remains unexplored how the cell wall, the inner membrane (IM), and the outer membrane (OM) effectively protect the cell from this pressure by bearing the resulting surface tension, thus preventing the formation of inner membrane bulges, abnormal cell morphology, spheroplasts and cell lysis. In this study, we have used molecular dynamics (MD) simulations combined with experiments to resolve how and to what extent models of the IM, OM, and cell wall respond to changes in surface tension. We calculated the area compressibility modulus of all three components in simulations from tension-area isotherms. Experiments on monolayers mimicking individual leaflets of the IM and OM were also used to characterize their compressibility. While the membranes become softer as they expand, the cell wall exhibits significant strain stiffening at moderate to high tensions. We integrate these results into a model of the cell envelope in which the OM and cell wall share the tension at low turgor pressure (0.3 atm) but the tension in the cell wall dominates at high values (>1 atm).

Optical observation of the ballooning and burst of E110 and E110G cladding tubes

Abstract During the last decades several experiments revealed interesting details of the ballooning and burst of nuclear cladding tubes in accident conditions involving high temperature and high pressure. To further investigate this phenomenon, a new set of experiments was conducted at MTA EK. A large tube furnace was fitted with two optical telescopes on opposite sides to observe the ballooning and burst of Russian E110 and E110G (sponge based E110) fuel cladding samples. The experiments were recorded using regular and high-speed cameras. Based on the captured images we developed a method to separate the contours of the cladding tubes during the ballooning to measure the change in diameter. Two successive modes of ballooning were observed, the uniform growth of the samples was followed by an asymmetrical, local ballooning (bulge formation) 2 s before the burst. It was found that the samples have bent by approximately 5° relative to their original axis in the latter phase and this was not caused by the jet effect of the high pressure argon gas escaping after the burst. Every sample opened up on the convex side of the bend. Axial grooves have formed on the surface of the E110G samples under tension. The high-speed camera was used to capture the cracking and the burst. Prior to the burst, a high temperature spot was observed at the position where the crack would initiate. The timescale of the crack propagation was 0.2 ms, the crack tip was estimated to be at least 100 °C hotter than the rest of the sample. The burst pressure was determined between 700 °C and 900 °C at different pressurization rates.

The WFC3 Galactic Bulge Treasury Program: Relative Ages of Bulge Stars of High and Low Metallicity∗

Abstract The Hubble Space Telescope/WFC3 multiband photometry spanning from the UV to the near-IR of four fields in the Galactic bulge, together with that for six template globular and open clusters, are used to photometrically tag the metallicity [Fe/H] of stars in these fields after proper-motion rejecting most foreground disk contaminants. Color–magnitude diagrams and luminosity functions (LF) are then constructed, in particular for the most metal-rich and most metal-poor stars in each field. We do not find any significant difference between the I-band and H-band LFs, hence turnoff luminosity and age of the metal-rich and metal-poor components therefore appear essentially coeval. In particular, we find that no more than ∼3% of the metal-rich component can be ∼5 Gyr old, or younger. Conversely, theoretical LFs match well to the observed ones for an age of ∼10 Gyr. Assuming this age is representative for the bulk of bulge stars, we then recall the observed properties of star-forming galaxies at 10 Gyr lookback time, i.e., at z ∼ 2, and speculate about bulge formation in that context. We argue that bar formation and buckling instabilities leading to the observed boxy/peanut, X-shaped bulge may have arisen late in the history of the Milky Way Galaxy, once its gas fraction had decreased compared to the high values typical of high-redshift galaxies. This paper follows the public release of the photometric and astrometric catalogs of the measured stars in the four fields.