Abstract As complex safety-critical system software becomes more powerful, so does the complexity of its design requirements. Modeling and analyzing design requirements at an early stage has become an integral part of the entire development process for complex safety-critical system software. Simulink is a system modeling and simulation tool used in aviation and other fields. Its model is stored in the form of MDL files. ART (Avionics Requirement Tools) is a requirement modeling and analysis verification tool for the aviation field. It uses VRM (Variable Relation Model) as the theoretical model and can accept VRM and its extended subsets as input models and verify them in the tool. The work of this paper is oriented to the typical software requirements in the field of avionics systems and proposes a formal modeling and verification method for Simulink-MDL models. First, the composition form and structure of the MDL model are analyzed in the article. The functions and semantics of various elements in the model are given. Then a formal modeling method of the MDL model is given. Finally, a simplified version of the flight guidance control system is used for modeling and verification to demonstrate the usability and effectiveness of this method.