Form Of Refractive Error Research Articles

Patterns of Refractive Errors among Medical Students at the University of Zambia School of Medicine

Background: Uncorrected refractive error is one of the leading causes of visual impairment and blindness world-over. The distribution and pattern of presentation is variable depending on various factors. Regardless of the type, refractive errors are easily correctable with spectacles if diagnosed early.
 Objective: The objective of this study was to evaluate the pattern of refractive errors among medical students at University of Zambia - School of Medicine.
 Methodology: This was a cross-sectional study conducted at the University Teaching Hospitals-Eye Hospital involving Master of Medicine, Master of Surgery (MBChB) students from third to seventh year of study at University of Zambia - School of Medicine, Ridgeway campus between October 2021 and March 2022. A total of 210 participants were recruited in the study. Subjects had non-cycloplegic autorefraction combined with a researcher administered questionnaire. Spherical equivalents (SE) ≥ - 0.50D were determined as myopia; SE of ≥ + 0.50D hyperopia and ≥ -0.50D cylinder as astigmatism. Statistical analysis was carried out using Stata version 13.0.
 Results: One hundred and forty-one (67.1%) subjects had a form of refractive error; 56.0%, 31.2% and 12.8% of them were astigmats, myopes or hyperopes, respectively. The prevalence of ametropia was 65.0 % in females and 69.0 % in males. Minus spherical errors ranged from -0.25 to -5.00D and plus spherical errors ranged from +0.25 to +3.00D. The mean spherical equivalent for the group was -0.45D. Parental history of refractive error was significantly associated with diagnosis of refractive error (p=0.001) while age and gender were not (p = 0.428 and 0.530, respectively). The majority (68.6%) of participants were not aware of their refractive error.
 Conclusion: The prevalence of refractive errors among medical students was high, with astigmatism being the most common type. The majority of those found with refractive error were not aware of the diagnosis.

Ocular pathology in patients referred to ophthalmology outpatient clinic at tertiary care hospital with headache

Introduction: Headache has multi-factorial causes; many primary or secondary headache disorders have ocular manifestations and benefit from the systematic ocular examination. Physicians at the point of the first contact should therefore be familiar with common ocular pathologies associated with a headache for appropriate referral.
 Method: This hospital-based descriptive cross-sectional study was conducted in the Ophthalmology Department of Patan Hospital. All patients with headache as primary symptom and were referred to an ophthalmology clinic for ocular evaluation by other departments were included. The study was done for 15 mo and 354 patients were evaluated for the cause of headache. Findings and diagnoses of consenting participants were recorded and analyzed.
 Result: All enrolled patients completed all the study procedures and were analyzed. The majority 61% were in 14-40 years. Homemaker was commonly affected 30.2% followed by students 25.4%. Any form of ocular pathology was detected in 76 % of patients. The majority of patients had no refractive errors (67.8%). Although any form of refractive error was more common in the presbyopia age group there was no statistically significant difference between different age groups. Most patients were orthophoric and only 11% of patients had vergence insufficiency. Among the ocular pathology dry eye, glaucoma suspects were more common.
 Conclusion: This study supports the ocular morbidities and headache symptoms are linked very frequently. Good ocular history is needed for appropriate patient referral to a specialist. Correction of a minor degree of refractive error and lubricating eye drop may relieve worrisome headaches for many patients.

AKSHADI TAILA NASYA AND VIDDHAKARMA IN THE MANAGEMENT OF PRATH-AMAPATALAGATATIMIRA - A PILOT STUDY

The eye is the prime sense organ among all sense organs, thus the word Drushti indicates the function of vision. Sushruta has described 12 Drishtigat rogas in Uttartantra. The anatomical consideration of Patalas & symptoms of the vitiated Doshas situated in these Patalas reveals that the word Timira which is described as an ocular pathol- ogy in Ayurveda is nothing but errors of refraction. Myopia, a form of refractive error where the distant vision is compromised, embraces a large section of the present-day population. In today's world, the pace of life has become fast, irregular and stressful, due to which the visual acuity gets impeded, which can be correlated with Timira de- scribed in Ayurvedic classics. Prathama Patalagata Timira is explained by all Acharyasas a Sadhya Drishtigata Roga. When vitiated Doshas reaches the Pratham Patala of the eye, the patients have blurred vision; this stage is characterized by Avyaktasdarshana (Sushruta) & Animitta Avyakata Rupa Darshana (Vagbhata). Vagbhata has described Nasya as a treatment modality for Urdhwajatrugata Vikaras Sushruta has described Viddhakarma as a treatment modality for Timira in Sutrasthana. Akshadi Taila Nasya Yoga is explained in Ashtang Hrudaya. In the present trial, 30 patients of Prathama Patalagata Timira were selected and Nasya of Akshadi Taila was done along with Viddhakarma. Keywords: Timira, Nasya, Akshadi Taila, Simple myopia, Viddhakarma

EFFICACY AND SAFETY OF LOW DOSE ATROPINE 0.01% IN SLOWING OF PROGRESSION OF MYOPIA

Background: Myopia, commonly referred to as short sightedness is a form of refractive error and is a very common cause of visual disability throughout the world.
 Methods: Hospital based prospective study conducted on 100 patients of Myopia attending to Department of Opthalmolgy.
 Results: There was no significant difference in the age, gender distribution, baseline myopia progression or follow-up duration between patients who used night application compared with daytime atropine. Effectiveness was better with daytime application.
 Conclusion: 1% atropine eye drops were well tolerated and efficacious for the retardation of progressive myopia in Indian eyes. Effectiveness was better with daytime application. Further studies are necessary to assess the role of 1% atropine in the rapid progressors and patients poorly responding to low-dose atropine.
 Keywords: Myopia, Atropine, low dose.

Novel truncation mutations in MYRF cause autosomal dominant high hyperopia mapped to 11p12\u2013q13.3

High hyperopia is a common and severe form of refractive error. Genetic factors play important roles in the development of high hyperopia but the exact gene responsible for this condition is mostly unknown. We identified a large Chinese family with autosomal dominant high hyperopia. A genome-wide linkage scan mapped the high hyperopia to chromosome 11p12–q13.3, with maximum log of the odds scores of 4.68 at theta = 0 for D11S987. Parallel whole-exome sequencing detected a novel c.3377delG (p.Gly1126Valfs*31) heterozygous mutation in the MYRF gene within the linkage interval. Whole-exome sequencing in other 121 probands with high hyperopia identified additional novel mutations in MYRF within two other families: a de novo c.3274_3275delAG (p.Leu1093Profs*22) heterozygous mutation and a c.3194+2T>C heterozygous mutation. All three mutations are located in the C-terminal region of MYRF and are predicted to result in truncation of that portion. Two patients from two of the three families developed angle-closure glaucoma. These three mutations were present in neither the ExAC database nor our in-house whole-exome sequencing data from 3280 individuals. No other truncation mutations in MYRF were detected in the 3280 individuals. Knockdown of myrf resulted in small eye size in zebrafish. These evidence all support that truncation mutations in the C-terminal region of MYRF are responsible for autosomal dominant high hyperopia in these families. Our results may provide useful clues for further understanding the functional role of the C-terminal region of this critical myelin regulatory factor, as well as the molecular pathogenesis of high hyperopia and its associated angle-closure glaucoma.

An idea of intuitive mobile diopter calculator for myopia patient

The diopter is the unit of measurement for the refractive power of a lens. Myopia is a form of refractive error which is a leading cause of visual disability throughout the world. The prevailing treatment of refractive errors which are commonly used in daily life are glasses and contact lenses. Although those methods can overcome myopia, many myopia patients still don’t really know how to measure their current refractive error in diopter. This condition may retard the progression of refractive treatment in the myopic individual. The common methods to measure refractive error are phoropter with Snellen chart and retinoscopy, but those expensive tools need expertise to operate. This paper presents the concept of measure the face to smartphone screen distance to provide the possibility to implement a mobile application as a low-cost alternative refractive measurement tool. The main objective is to investigate the feasibility of mobile application to help patients with myopia measuring their blur line distances and evaluate their diopter levels independently. The experimental results reveal that, with 80.5 usability score the overall functionality of proposed application can be categorized as usable to users and feasible for future implementation.

Management of Simple Myopia with Anantadi Ghrita: A Case Report

Ayurveda can serve better in many disease conditions, where conventional system face several limitations. Refractive errors are among such conditions, where effective management is becoming a challenge. Myopia or short sight, is that form of refractive error wherein parallel rays of light come to focus in front of sentient layer of the retina when the eye is at rest. Around 60% cases of blurred vision are due to simple myopia and this may present from simple eye strain to blurring of vision. The contemporary medicine advices optical correction and lasik surgery for managing this condition; whereas Ayurveda provides better care and prevent complications in initial stages. As many of the individuals may not prefer surgery; a great emphasise on the alternative measures for satisfactory management is the need of the hour. In this paper, a case of simple myopia managed with Ayurvedic protocol has been presented.

Refractive Errors and Spectacle Use Behavior among Medical Students in a Nigerian Medical School

Aim: To determine the prevalence of refractive errors and spectacle use behavior among medical students in University of Calabar Teaching Hospital, Nigeria. Study Design: Cross sectional study. Place and Duration of Study: Department of Ophthalmology, University of Calabar Teaching Hospital, Calabar, Cross River State, Nigeria, between April 2010 and July 2010. Methodology: The study population consisted of fifth year medical students. Subjects had cycloplegic auto refraction with Topcon auto refractor during their rotation in ophthalmology at the Ophthalmology department of the University of Calabar Teaching Hospital. A spherical equivalents (SE) ≥ +0.50D were determined as hyperopia; SE of >Original Research Article British Journal of Medicine & Medical Research, 4(13): 2581-2589, 2014 2582 0.50D myopia and >-0.50D cylinder as astigmatism. Statistical analysis, which included chi-square test was carried out with Statistical Package for Social Sciences (SPSS) version 20.0. Results: Sixty-six (79.5%) of subjects had a form of refractive error; 63.6%%, 16.7% and 19.7% were myope, hyperope or simple estigmat, respectively. The prevalence of ametropia was 82% in female and 78% in males. The association between refractive errors and gender was not statistically significant (p = 0.35, 95% Confidence Interval [CI], 0.34-0.36).Minus spherical errors ranged from -0.16 to -5.25 diopters (D) and plus spherical errors ranged from +0.25 to +1.00D, spherical equivalent between -0.25D and 2.75D being the most common type (85.5%). Eight students (12.1%) were wearing glasses at the time of the study corresponding with 10 (15.2%) who had eye pains while reading. Conclusion: The prevalence of refractive errors among fifth year medical students of the University of Calabar was high and eyeglasses were worn by students who were symptomatic.

Is myopia a public health problem in India?

Myopia, a form of refractive error is a leading cause of visual disability throughout the world. In India uncorrected refractive errors are the most common cause of visual impairment and second major cause of avoidable blindness. Due to this the public health and economic impact of myopia is enormous. Although school vision screening programme is very successful in many states, still a significant number of school going children remain unidentified and the unmet need for correcting refractive errors in children appears to be significant.

Distance refractive error among Aboriginal people attending eye clinics in remote South Australia

To determine the prevalence of distance refractive error among Aboriginal people attending eye clinics in remote South Australia. A clinic-based cross-sectional study was conducted that involved opportunistic sampling of Aboriginal people attending eye clinics in remote South Australia. There were 189 individuals who were invited to participate in the study all of whom underwent ophthalmic examination. This examination included measurement of pinhole-corrected visual acuity and non-cycloplegic autorefraction. Automated refractive error examinations were performed on 148 people within this sample. The mean age was 44.8 +/- 14.5 years and women comprised 57.7% of the sample. The overall mean refractive error was -0.01 +/- 1.8 D (SD). The prevalence of myopia (spherical equivalent (SE) < -0.5 D), high myopia (SE less than or equal to -6.0 D), hypermetropia (SE > 0.5 D), astigmatism (cylinder at least -0.5 D) and anisometropia (difference in SE of >0.5 D) was 31.1%, 0.7%, 33.1%, 55.8% and 45.9%, respectively. Further analyses revealed significant age-related trends with both myopia and hypermetropia. There were no gender associations with any form of refractive error. Of those people with clinically significant refractive error, 51/148 (34%), only four people owned distance spectacles. There continues to be a level of uncorrected distance refractive error within these patients. This represents a need to screen for refractive error among Aboriginal people in remote locations and to provide them with appropriate spectacle correction.