In the last fifty years, Latin America witnessed both a stark rise in violence between drug trafficking organizations and militarized police forces, as well as a significant expansion of social movements. Few movements, however, have explicitly mobilized against drug violence due to the extreme dangers of speaking out against armed and corrupt actors. In this paper, we extend our understanding of social movements and drug violence by analyzing the relationship between feminist movements against gender-based violence—or feminist anti-violence (FAV)—and drug violence. We conceive FAV as a “tangential movement” to drug-related violence, mobilizing around its root causes and consequences without directly targeting its perpetrators. The paper examines case studies of feminist anti-violence movements in three cities: Ciudad Juárez, Mexico; Caracas, Venezuela; and Medellín, Colombia. We show that as feminist movements mobilize against gender-based violence, they provide an alternative, and safer, avenue for citizens to mobilize against drug-related violence by working to (a) curb intimate forms of abuse and trauma that create intergenerational cycles of violence; (b) decrease impunity by demanding the state hold perpetrators of violence accountable; (c) strengthen government institutions and their relations with civic organizations, thereby helping enforce democracy and human rights; (d) challenge patriarchal notions of violent masculinity; and (e) organize against structural inequality that bolsters participation in the drug trade. By considering how feminist anti-violence movements help address the underlying causes of drug violence, we can identify new pathways for organizing around human security in contexts where direct channels of confrontation are too risky.