PurposeThis study aimed to determine the effect of a forced-air warming blanket placed on different body parts on the core temperature of patients undergoing elective open abdominal surgery. DesignProspective, single-center, randomized, controlled, single-blind trial. MethodsA total of 537 patients who underwent open abdominal surgery were randomized into groups A, B, and C and provided with different forced-air warming blankets. Group A was given an upper body blanket, group B a lower body blanket, and group C an underbody blanket. The incidence of intraoperative hypothermia, the time maintaining the core temperature over 36 ℃ before hypothermia, the duration of hypothermia, the rewarming rate, and relevant complications were compared among three groups. FindingsIntraoperative hypothermia occurred in 51.4% of patients in group B, 37.6% of patients in group A, and 34.1% of patients in group C (P = .002). Maintaining the core temperature above 36 ℃ was longer before hypothermia in groups A and C (log-rank P = .006). In groups A and C, the duration of hypothermia was shorter, the rewarming rate was higher, and the incidence of shivering and postoperative nausea and vomiting were lower, compared to group B. ConclusionsIn patients undergoing elective open abdominal surgery, a forced-air warming blanket on the upper body part or underbody area decreased intraoperative hypothermia, prolonged the time to maintain the core temperature above 36 ℃ before hypothermia, and could better prevent further hypothermia when the core temperature had decreased below 36 ℃. In addition, it was significantly superior in reducing shivering and postoperative nausea and vomiting in the postanesthesia care unit.