For a degree sequence, we define the set of edges that appear in every labeled realization of that sequence as forced, while the edges that appear in none are define as forbidden. We examine the structure of graphs in which the degree sequences contain either forced or forbidden edges. The results include the determination of the structure of the forced or forbidden edge sets, the relationship between the sizes of forced and forbidden sets for a sequence, and the structural consequences to their realizations. This includes showing that the diameter of every realization of a degree sequence containing forced or forbidden edges is no greater than 3, and that these graphs are maximally edge-connected.