2D nanomaterials-infused electrochemical microfluidic sensors mark a paradigm shift in precision sensing technology. Leveraging the unique properties of materials like carbons, transition metal and molecularly imprinted polymers, these sensors redefine the benchmarks for electrochemical sensing with their extraordinary sensitivity, rapid response kinetics, and remarkably low detection limits. The integration of a microfluidic system further enhances their capabilities, providing meticulous control over sample volumes and reaction kinetics, ensuring unparalleled reliability and reproducibility in real-time monitoring applications. This amalgamation of advanced nanomaterials and microfluidic technology not only sets new standards for precision sensing but also opens avenues for transformative applications across diverse fields. In the realm of food safety, these sensors emerge as pioneering tools, offering exceptional specificity for the precise detection of contaminants, pathogens, and spoilage indicators. Their rapid, on-site analysis capabilities revolutionize traditional testing methods, enabling timely interventions and elevating the overall quality assurance in the food industry. Simultaneously, their impact extends to environmental ecology, where the sensors play a crucial role in monitoring pollutants, heavy metals, and environmental stressors in real-time. The compact design and portability of these sensors facilitate on-site environmental monitoring, transcending the limitations of conventional laboratory-based testing and contributing to more sustainable and resilient ecosystems. Beyond their technological prowess, these sensors carry significant societal and economic implications. Their compact and portable nature streamlines on-site analyses, minimizing logistical challenges associated with sample transportation and centralized laboratory facilities. This efficiency not only enhances monitoring processes but also holds the potential to revolutionize resource allocation in sectors reliant on rapid and reliable analytical insights. In essence, 2D nanomaterials-based electrochemical microfluidic sensors represent a transformative leap towards precision sensing, promising a future where safeguarding the integrity of our food supply and ecological systems is seamlessly intertwined with technological innovation. Figure 1
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