You have accessJournal of UrologyBenign Prostatic Hyperplasia: Medical and Hormonal Therapy1 Apr 20111970 DOES THE QUALITY OF LIFE CONTINUE TO IMPROVE FOLLOWING MEDICAL TREATMENT OF LUTS? PROSPECTIVE STUDY WITH 17 YEARS FOLLOW-UP John Graham, Bhasker Smani, Thomas Lam, and Said Mishriki John GrahamJohn Graham Aberdeen, United Kingdom More articles by this author , Bhasker SmaniBhasker Smani Aberdeen, United Kingdom More articles by this author , Thomas LamThomas Lam Aberdeen, United Kingdom More articles by this author , and Said MishrikiSaid Mishriki Aberdeen, United Kingdom More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2011.02.2195AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES To assess the long-term clinical effectiveness, quality of life (QoL), bother and satisfaction for patients with lower urinary tract symptoms (LUTS) due to benign prostatic enlargement (BPE) receiving medical treatment. METHODS A prospective cohort study enrolled men referred to a tertiary university hospital for further evaluation and treatment of LUTS between January1993 and September 1994. 178 patients received medical treatment. They were recruited into this protocol based study using validated self-reported questionnaires. Assessment included AUA symptom score, flow rates, measurement of QoL symptom score, bother symptom score and satisfaction. Data were collected at baseline, 3 months, 6 months, 6 years and 12 years of follow-up. After 17 years, the final patient status was reviewed. RESULTS Fifty patients (28%) underwent TURP within the 17 year follow-up period. For the 128 patients that were maintained on medical treatment, there was a considerable improvement in all symptom scores as shown in table. The improvements in the AUA, QoL and bother scores were consistent. For the 12 years follow-up this was statistically significant as shown in table. At 17 years, none of the patients were attending secondary care follow-up. Baseline 6 months 6 years 12 years P value for the 12 years follow-up Follow-up Mean (range) Mean (range) Mean (range) Mean (range) AUA 13.6 (1–30 10.57 (1–20) 11.1 (1–25) 10.8 (1–34) 0.01 Bother 11.1 (1–31) 8.86 (6–22) 8.6 (0–20) 8.2 (1–26) QoL 6.3 (1–17) 5 (0–12) 3.8 (0–9) 3.8 (1–14) CONCLUSIONS Medical treatment not only proved to be clinically effective, but also improved QoL and bother symptoms. This was associated with long-term high patient-rated satisfaction. © 2011 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 185Issue 4SApril 2011Page: e788-e789 Advertisement Copyright & Permissions© 2011 by American Urological Association Education and Research, Inc.MetricsAuthor Information John Graham Aberdeen, United Kingdom More articles by this author Bhasker Smani Aberdeen, United Kingdom More articles by this author Thomas Lam Aberdeen, United Kingdom More articles by this author Said Mishriki Aberdeen, United Kingdom More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...