We thank Dr. Sethi for the interest in our article.1 We agree the management of status epilepticus (SE) should be progressive using successive lines of antiseizure drugs (ASD), as recommended by the European and American guidelines.2,3 Therapeutic coma (TC) is sometimes needed; however, since the benefits of TC are not yet clear,4 we strongly believe that a “shotgun” approach should be avoided because it might harm the patient.5 We demonstrated that a more conservative approach was not associated with increased mortality, but avoiding TC correlated with a shorter length of hospital stay and a trend towards a better functional outcome.1 The best approach, as Dr. Sethi suggests, is probably to strictly adhere to the proposed treatment algorithms,3 using correctly dosed benzodiazepines followed by one nonsedating ASD. Eventually, after a careful case-by-case risk–benefit assessment, a decision to start TC may be taken. TC is often designated for patients with refractory generalized convulsive SE (awaiting further studies); nevertheless, in patients with focal SE and partly preserved consciousness, subsequent trials of nonsedating ASD before considering TC appears more appropriate.4