Forty-seven compounds among synthetic phenolic and amino antioxidants and ultraviolet filters, three suites of widely used chemical additives, were measured in eighteen popular children's car seats (fabric, foam, and laminated composites of both layers) marketed in the United States in 2018. Significantly higher levels of target compounds were found in foam and composite samples than in fabric samples. Median total concentrations of phenolic antioxidants and their transformation products ranged from 8.11 μg/g in fabric to 213 μg/g in foam In general, isooctyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl) propionate (AO-1135) and 2,4-di-tert-butylphenol (24-DBP) were the most abundant among all target compounds with maximum levels of526 μg/g in composite and 13.7 μg/g, respectively. The total concentrations of amino antioxidants and their transformation products and of ultraviolet filters were at least one order of magnitude lower than those of phenolic antioxidants, with medians of 0.15–37.1 μg/g and 0.29–1.81 μg/g, respectively, in which the predominant congeners were 4-tert-butyl diphenylamine (BDPA), 4,4′-di-tert-butyl diphenylamine (DBDPA), 4-tert-octyl diphenylamine (ODPA), 2,4-dihydroxybenzophenone (BP-1), 2-hydroxy-4-methoxybenzophenone (BP-3), and 2-(2-benzotriazol-2-yl)-4-methylphenol (UV-P). Large variabilities in usage of these chemicals resulted in different compositional patterns among the car seats. These results suggest that these compounds are major polymeric additives in children's car seats as they are present at greater levels than previously measured groups of chemicals like brominated flame retardants and per- and polyfluoroalkyl substances. Given the documented toxic potentials of synthetic antioxidants and ultraviolet filters, their abundances in children products are a cause for concern.