The anti-collision device has the effect of protecting both the ship and bridge. Two forms of corrugated-core infilling foam sandwich composite structure were developed to study their impact characteristics. The influence of structural geometric parameters on the peak force, failure modes, and energy absorption were analyzed via low-speed impact tests. The results show that the impact energy was almost absorbed by all specimens under impact velocity of 4 m/s. Compared with the dislocation corrugated core specimen (DC), the peak impact force of the parallel corrugated core specimen (PC) got a maximum of a 26.54% decline on the peak value. PC effectively improved the structural uniform compression deformation ability. Little influence on the interaction between wavelength and lattice thickness was proved. The impact peak force of PC was more sensitive to the change of lattice thickness, while the impact peak force of DC was more sensitive to the change of lattice wavelength. Numerical simulation predicted the impact peak force value and stress distribution of specimens. The effect of foam density on the peak force and the impact velocity on the energy absorption were investigated using the finite element (FE).