Introduction Calcium trisilicate derivatives havewidely been used as dentin and enamel substitutes recently. These cements have excellent biological properties, but they do not show fluoride release. The release of fluoride from dental materials is a very important property of a material in restorative applications as fluoride confers antibacterial and anti-cariogenic properties. This study thus attempts to incorporate fluoride in the form of sodium fluorosilicate and hydrofluoric acid into Biodentine to assess its fluoride-releasing properties. Methods Biodentine was modified by adding 7% sodium fluorosilicate in the powder and 10% hydrofluoric acid to the liquid. Fluoride release was measured using a sodium 2-(parasulfophenylazo)-1,8-dihydroxy-3,6-naphthalenedisulfonate (SPADNS) spectrophotometer after 1, 3, 7, 14, 21, and 28 days. The compressive strength of the modified material was measured using a universal testing machine. Results Fluoride release was found to be higher in the group that had both powder and liquid modified than in groups in which either of the components were modified. The difference was found to be statistically significant(p<0.001). Conclusion Incorporation of fluoride in Biodentine is feasible with acceptable release of fluoride without adversely affecting the compressive strength of the Biodentine.