Fluorescent Chemosensor For Fe3 Research Articles

A novel selective fluorescent chemosensor for Fe 3+ ions based on phthalonitrile dimer: synthesis, analysis, and theoretical studies.

Phenyl-4,4-di(3,6-dibutoxyphthalonitrile) ( 3 ) was synthesized by the reaction of 1,4-phenylenebisboronic acid ( 1 ) and 4-bromo-3,6-dibutoxyphthalonitrile ( 2 ), using Suzuki cross-coupling reaction. The newly synthesized compound ( 3 ) was characterized by FT-IR, MALDI-MS, ESI-MS, 1 H-NMR, 13 C-NMR, and 13 C-DEPT-135-NMR. The fluorescence property of phenyl-4,4-di(3,6-dibutoxyphthalonitrile) ( 3 ) towards various metal ions was investigated by fluorescence spectroscopy, and it was observed thatthe compound ( 3 ) displayed a significantly ‘turn-off’ response to Fe 3+ , which was referred to 1:2 complex formation between ligand ( 3 ) and Fe 3+ . The compound was also studied via density functional theory calculations revealing the interaction mechanism of the molecule with Fe 3+ ions.

Fe3+-Sensitive Carbon Dots for Detection of Fe3+ in Aqueous Solution and Intracellular Imaging of Fe3+ Inside Fungal Cells.

In this article, the Fe3+-sensitive carbon dots were obtained by means of a microwave-assisted method using glutamic acid and ethylenediamine as reactants. The carbon dots exhibited selective response to Fe3+ ions in aqueous solution with a turn-off mode, and a good linear relationship was found between (F0-F)/F0 and the concentration of Fe3+ in the range of 8–80 μM. As a result, the as-synthesized carbon dots can be developed as a fluorescent chemosensor for Fe3+ in aqueous solution. Moreover, the carbon dots can be applied as a fluorescent agent for fungal bioimaging since the fungal cells stained by the carbon dots were brightly illuminated on a confocal microscopy excited at 405 nm. Furthermore, an increase in the concentration of intracellular Fe3+ could result in fluorescence quenching of the carbon dots in the fungal cells when incubated in the Tris-HCl buffer solution containing Fe3+. However, due to EDTA might hinder Fe(III) to enter the fungal cells, incubation in Fe(III)-EDTA complex solution exerted negligible effect on the fluorescence of fungal cells labeled by the carbon dots. Therefore, the carbon dots can serve as a potential probe for intracellular imaging of Fe3+ inside fungal cells.

Triazine-containing blue emitting Hyperbranched polyamide with donor-acceptor architecture: synthesis, characterization, optoelectronic properties, and sensing behaviors toward ferric ions

Two novel blue-emitting triazine-containing hyperbranched amides with donor-acceptor architecture were designed and synthesized via a one-pot polycondensation using 2,4,6-tris(4-carboxyphenyl)-1,3,5-triazine (H3TATB) and p-phenylenediamine as reaction materials. The prepared polymers were characterized using fourier transform infrared spectroscopy (FTIR), 1H–nuclear magnetic resonance (1H–NMR), and gel permeation chromatography (GPC) analyses. The two polymers are almost amorphous and are soluble in DMSO. Their solutions mainly emitted strong blue light (457–476 nm). The fluorescence quantum yields (QYs) in DMSO were calculated as 41% and 8% for P1–1 and P2–1, respectively. Density functional theory (DFT) calculations demonstrated that the highest occupied molecular orbit (HOMO) and lowest unoccupied molecular orbit (LUMO) were effectively separated with p-phenylenediamine as a donor unit and H3TATB as an acceptor unit. The effective HOMO−LUMO separation helps to induce intramolecular charge transfer from the HOMO to the LUMO. This results a relatively small energy gap between the singlet and triplet excited states, and as a consequence, these polymers are expected to harness both singlet and triplet excitons for light emission, leading to high external electroluminescence efficiency. The merits of the two polymers are organo-solubility and high fluorescence quantum yield. Both P1–1 and P2–1 are sensitive fluorescent indicators for Fe3+ ion. They are potential useful in the area of blue light emitting, display and fluorescent chemosensor for Fe3+ ion.

A new rhodamine fluorescent OFF-ON-OFF probe for selective sensing of Fe3+ and AcO- in aqueous media and living cells

A new fluorescent chemosensor for Fe3+ was developed based on a rhodamine platform. L displayed highly selective and sensitive “OFF-ON” fluorescence response and naked-eye color change to Fe3+ in aqueous solution. The resulting L-Fe3+ complex was found to act as a selective“ ON-OFF” fluorescence probe for AcO- against common anions and cations with a Fe3+ displacement approach. The detection limits of L to Fe3+ and L-Fe3+ complex to AcO- were estimated to be 6.04×10-8 mol/L and 7.51×10-8 mol/L, respectively. The good biocompatibility of L enabled the investigation of fluorescent response for Fe3+ and AcO- in living Ana-1 cells by confocal microscope.

A novel turn-on colorimetric and fluorescent sensor for Fe3+ and its application in living cells

Abstract A novel turn-on colorimetric and fluorescent sensor 1 based on rhodamine B was developed as a colorimetric and fluorescent chemosensor for Fe3+. Upon addition of Fe3+ in aqueous ethanol, the 1 displayed a distinct color change from colorless to pink and a significant fluorescence enhancement, which can be directly detected by the naked eye. The stoichiometry of 1 to Fe3+ complex was found to be 1:1 and the detection limit was determined as low as 7.68 × 10−7 M. The results suggest that the sensor 1 may provide a conveniently method for visual detection of Fe3+ with high sensitivity. Furthermore the sensor has been utilized for fluorescence imaging of Fe3+ in living cells.

A new rhodamine-based chemosensor for turn-on fluorescent detection of Fe3+

A new fluorescent probe RH-Fe was developed as a colorimetric and fluorescent chemosensor for Fe3+.

A new fluorescent chemosensor for Fe3+ based upon 2,5-diphenylfuran and 8-hydroxyquinoline

• A new 8-hydroxyquinoline-based fluorescent chemosensor 1 was synthesized. • The structure of the sensor 1 was confirmed by single crystal X-ray diffraction. • The sensor 1 can be used to determine Fe 3+ ion in aqueous DMF with high selectivity. A new fluorescent chemosensor based upon 2,5-diphenylfuran and 8-hydroxyquinoline was designed and synthesized. Its structure was confirmed by single crystal X-ray diffraction and its photophysical properties were studied by absorption and fluorescence spectra. This compound can be used to determine Fe 3+ ion with high selectivity among a series of cations in aqueous DMF. This sensor forms a 1:1 complex with Fe 3+ and displays fluorescent quenching.

Selective Chemosensor of Fe3+ Based on Fluorescence Quenching by 2,2′‐Bisbenzimidazole Derivative in Aqueous Media

Abstract2,2′‐Bisbenzimidazole derivative (L) was designed as a fluorescent chemosensor for Fe3+. This structurally simple chemosensor displays significant fluorescence quenching with increasing concentrations of Fe3+. L exhibited high selectivity and antidisturbance for Fe3+ among environmentally relevant metal ions in aqueous media. The method of Job's plot indicated the formation of 1:2 complex between L and Fe3+, and the possible binding mode of the system was also proposed. In addition, further study demonstrates the detection limit on fluorescence response of the sensor to Fe3+ is down to 10−7 mol·L−1 range. The binding mode was investigated by fluorescence spectra, ESI‐MS, IR data, 1H NMR, 13C NMR and crystal data.

Synthesis of an amphiphilic copolymer bearing rhodamine moieties and its self-assembly into micelles as chemosensors for Fe3+ in aqueous solution

We report on the fabrication of an amphiphilic random copolymer-based colorimetric and fluorescent chemosensor for Fe3+ ions that was prepared by free radical polymerization of a novel rhodamine-based Fe3+-recognizing monomer, R6GEM, with N-vinylpyrrolidone (NVP). Because of its amphiphilic property, the copolymer P(NVP-co-R6GEM) can self-assemble into micelles, which allows it to be used as a chemosensor in aqueous solution. Upon addition of Fe3+ ions to the micelle solution, visual color change and fluorescence enhancement were observed. Moreover, other metal ions did not induce obvious changes to the absorption and fluorescence spectra. The water dispersibility and biocompatibility of these polymer micelles could provide a new strategy for detecting analytes in environmental and biological systems.

Fluoranthene-based pyridine as fluorescent chemosensor for Fe3+

Abstract A fluoranthene based fluorescent chemosensor 2-(7,10-diphenyl-fluoranthen-8-yl)-pyridine ( B ) which shows excellent selectivity towards Fe 3+ is described. Upon addition of FeCl 3 into the ethanol solution of B , it exhibits a great decrease of emission intensity against environmental and biological samples. Further experiments demonstrate that Fe(NO 3 ) 3 has the similar influence as FeCl 3 on the emission spectra of B while Fe 2 (SO 4 ) 3 has no influence on that of B .

Aminoxy-linked rhodamine hydroxamate as fluorescent chemosensor for Fe3+ in aqueous media

Abstract A novel feric ion-selective rhodamine-based fluorescent chemosensor, which contains a bis-aminoxy chain moiety, has been developed. The multi-dentate binding site of rhodamine fluorophore shows selective detection of ferric iron over other biologically important metal ions in aqueous media and also shows 1:1 binding stoichiometry.